The DOI matches its Crossref record; 180 of the 181 references it cites were found in a registry or an index.
An insight into gut microbiota and its functionalities
Open accessAbstract
Gut microbiota has evolved along with their hosts and is an integral part of the human body. Microbiota acquired at birth develops in parallel as the host develops and maintains its temporal stability and diversity through adulthood until death. Recent developments in genome sequencing technologies, bioinformatics and culturomics have enabled researchers to explore the microbiota and in particular their functions at more detailed level than before. The accumulated evidences suggest that though a part of the microbiota is conserved, the dynamic members vary along the gastrointestinal tract, from infants to elderly, primitive tribes to modern societies and in different health conditions. Though the gut microbiota is dynamic, it performs some basic functions in the immunological, metabolic, structural and neurological landscapes of the human body. Gut microbiota also exerts significant influence on both physical and mental health of an individual. An in-depth understanding of the functioning of gut microbiota has led to some very exciting developments in therapeutics, such as prebiotics, probiotics, drugs and faecal transplantation leading to improved health.
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“Supported by a body of studies (19, 32, 41–43), psychobiotics have been shown to modulate the gut microbiota, stimulate the development of beneficial bacteria, and alleviate conditions linked to gut dysbiosis, such as depression and anxiety.”
From Unveiling the therapeutic symphony of probiotics, prebiotics, and postbiotics in gut-immune harmony (2024) · cites this paper as [41]
In the citing paper
“Through the synthesis of neurotransmitters like serotonin, gamma-aminobutyric acid, and dopamine, psychobiotics contribute to mood regulation and stress response, potentially alleviating depressive and anxious feelings.”
From Unveiling the therapeutic symphony of probiotics, prebiotics, and postbiotics in gut-immune harmony (2024) · cites this paper as [41]
In the citing paper
“Psychobiotics impact the hypothalamic–pituitary–adrenal (HPA) axis, reducing stress hormone levels and promoting mental well-being.”
From Unveiling the therapeutic symphony of probiotics, prebiotics, and postbiotics in gut-immune harmony (2024) · cites this paper as [41]
In the citing paper
“Psychobiotics may enhance synaptic plasticity, neurotrophic factor production, and maintain the blood–brain barrier’s integrity, positively impacting learning, memory retention, and brain health.”
From Unveiling the therapeutic symphony of probiotics, prebiotics, and postbiotics in gut-immune harmony (2024) · cites this paper as [41]
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Effect of Diet and Dietary Components on the Composition of the Gut Microbiota
Beam, A., Clinger, E., & Hao, L. (2021) · Nutrients · doi:10.3390/nu13082795 · Cited by 576
Intestinal Barrier in Human Health and Disease
Tommaso, N. D., Gasbarrini, A., & Ponziani, F. R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312836 · Cited by 577
Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders
Chopyk, D. M., & Grakoui, A. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.04.077 · Cited by 504
Montero, C. G., Fraile‐Μartinez, O., Gomez-Lahoz, A. M., Pekarek, L., Castellanos, A. J., Noguerales-Fraguas, F., Coca, S., Guijarro, L. G., García‐Honduvilla, N., Asúnsolo, Á., et al. (2021) · Nutrients · doi:10.3390/nu13020699 · Cited by 487
The interaction among gut microbes, the intestinal barrier and short chain fatty acids
Ma, J., Piao, X., Mahfuz, S. U., Long, S., & Wang, J. (2021) · Animal nutrition · doi:10.1016/j.aninu.2021.09.012 · Cited by 432
Metadata
- Authors
- Adak, A., & Khan, M. R.
- Affiliations
- Institute of Advanced Study in Science and Technology (IN)
- Corresponding author
- Khan, Mojibur R.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2018-10-13
- Volume
- 76
- Issue
- 3
- Pages
- 473-493
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- PMC
- PMC11105460
- OpenAlex
- W2896269751
- Cited by
- 1,485
- References
- 181
- Citations by year
- 2026: 191 · 2025: 393 · 2024: 372 · 2023: 232 · 2022: 176 · 2021: 90 · 2020: 22 · 2019: 8
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cellular and Molecular Life Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Department of Science and Technology, India (under Unit of Excellence Project (BT/550/NE/U-Excel/2014))
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- gut microbiota, microbiome diversity, microbiota dynamics, gastrointestinal tract, host immunity, host metabolism, prebiotics, probiotics, microbiota-based therapy, fecal microbiota transplantation, culturomics
- MeSH terms
- Gastrointestinal Microbiome, Humans, Symbiosis, Computational Biology, Gastrointestinal Tract
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