Adverse effects of antipsychotic drugs: survey of doctors’ versus patients’ perspective.
Abstract
Aims Almost no data are available on whether patients and doctors have similar or dissimilar opinions on the presence and level of distress due to antipsychotic adverse effects. The aim of this survey is to compare doctors' versus patients' perspective on the presence and level of distress due to antipsychotic adverse effects in a sample of patients under the care of the South-Verona mental health services.Methods All patients exposed to antipsychotic drugs during a census period of 6 months were identified. For each included subject, socio-demographic, clinical and treatment data were extracted. Patients' perspective on antipsychotic adverse effects was measured by means of the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS). The LUNSERS was similarly employed to measure doctors' perspective on antipsychotic adverse effects.Results During the recruitment period, 243 patients taking antipsychotic drugs were enrolled. The correlation between the total LUNSERS score reported by patients and doctors was very low (correlation coefficient 0.22, 95% confidence interval 0.15-0.30). On average, patients perceived more adverse effects and with a significant higher distress than doctors. Multivariate analyses found no factors simultaneously associated with both patient and doctor ratings of adverse effects.Conclusion Our study suggests that doctors, researchers and health care providers should increasingly consider patient and doctor perspectives as two complementary dimensions that may provide different insights in the evaluation of antipsychotic drugs. Integrating different points of view may represent a way to develop a better therapeutic alliance that might decrease the likelihood of nonadherence.
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Psychiatric patients often view pharmacological interventions more negatively than the doctors who prescribe them.
“Psychiatric patients often view pharmacological interventions more negatively than by the doctors who prescribe them (Nosè et al., 2012)”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Nosè et al., 2012
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“Psychiatric patients often view pharmacological interventions more negatively than by the doctors who prescribe them (Nosè et al., 2012) and it is possible that patients may perceive a non-pharmacological adjunctive approach more favorably.”
- Authors
- Nosè, M., Mazzi, M. A., Esposito, E., Bianchini, M., Petrosemolo, P., Ostuzzi, G., Tansella, M., & Barbui, C.
- Affiliations
- University of Verona (IT)
- Corresponding author
- Nosè, Michela
- Venue
- Social Psychiatry and Psychiatric Epidemiology
- Published
- 2010-11-28
- Volume
- 47
- Issue
- 1
- Pages
- 157-164
- ISSN
- 0933-7954 (ISSN-L)
- 1433-9285
- OpenAlex
- W2034105736
- Cited by
- 16
- References
- 31
- Citations by year
- 2024: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 3 · 2014: 3 · 2013: 1 · 2012: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Social Psychiatry and Psychiatric Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Health Professions › General Health Professions › Mental Health and Patient Involvement
- Keywords
- antipsychotic adverse effects, patient perspectives, patient distress, therapeutic relationship, medication adherence, schizophrenia, mental health services
- MeSH terms
- Adult, Attitude of Health Personnel, Attitude to Health, Community Mental Health Services, Data Collection, Female, Humans, Italy, Male, Middle Aged, Physician-Patient Relations, Physicians, Antipsychotic Agents, Young Adult
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