The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Comfort and patient-centred care without excessive sedation: the eCASH concept
Open accessAbstract
We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care. This strategy, which may be regarded as an evolution of the Pain, Agitation and Delirium guidelines, is conveyed in the mnemonic eCASH-early Comfort using Analgesia, minimal Sedatives and maximal Humane care. eCASH aims to establish optimal patient comfort with minimal sedation as the default presumption for intensive care unit (ICU) patients in the absence of recognised medical requirements for deeper sedation. Effective pain relief is the first priority for implementation of eCASH: we advocate flexible multimodal analgesia designed to minimise use of opioids. Sedation is secondary to pain relief and where possible should be based on agents that can be titrated to a prespecified target level that is subject to regular review and adjustment; routine use of benzodiazepines should be minimised. From the outset, the objective of sedation strategy is to eliminate the use of sedatives at the earliest medically justifiable opportunity. Effective analgesia and minimal sedation contribute to the larger aims of eCASH by facilitating promotion of sleep, early mobilization strategies and improved communication of patients with staff and relatives, all of which may be expected to assist rehabilitation and avoid isolation, confusion and possible long-term psychological complications of an ICU stay. eCASH represents a new paradigm for patient-centred care in the ICU. Some organizational challenges to the implementation of eCASH are identified.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Barr, J., Fraser, G. L., Puntillo, K., Ely, E. W., Gélinas, C., Dasta, J. F., Davidson, J. E., Devlin, J. W., Kress, J. P., Joffe, A. M., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182783b72 · Cited by 3,765
Schweickert, W. D., Pohlman, M. C., Pohlman, A. S., Nigos, C., Pawlik, A. J., Esbrook, C. L., Spears, L., Miller, M., Franczyk, M., Deprizio, D., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60658-9 · Cited by 3,339
Kress, J. P., Pohlman, A. S., O'Connor, M. F., & Hall, J. B. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005183422002 · Cited by 2,981
Ely, E. W., Margolin, R., Francis, J., May, L., Truman, B., Dittus, R., Speroff, T., Gautam, S., Bernard, G. R., & Inouye, S. K. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107000-00012 · Cited by 2,422
Girard, T. D., Kress, J. P., Fuchs, B. D., Thomason, J. W., Schweickert, W. D., Pun, B. T., Taichman, D. B., Dunn, J. G., Pohlman, A. S., Kinniry, P. A., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60105-1 · Cited by 2,055
Ely, E. W., Truman, B., Shintani, A., Thomason, J. W. W., Wheeler, A. P., Gordon, S., Francis, J., Speroff, T., Gautam, S., Margolin, R., et al. (2003) · JAMA · doi:10.1001/jama.289.22.2983 · Cited by 1,707
Riker, R. R. (2009) · JAMA · doi:10.1001/jama.2009.56 · Cited by 1,672
Pandharipande, P. P., Pun, B. T., Herr, D. L., Maze, M., Girard, T. D., Miller, R. R., Shintani, A. K., Thompson, J. L., Jackson, J. C., Deppen, S. A., et al. (2007) · JAMA · doi:10.1001/jama.298.22.2644 · Cited by 1,451
Self-citationGeneral Anesthesia, Sleep, and Coma
Brown, E. N., Lydic, R., & Schiff, N. D. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0808281 · Cited by 1,350
Jakob, S. M. (2012) · JAMA · doi:10.1001/jama.2012.304 · Cited by 980
Cited by
The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families
Ely, E. W. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002175 · Cited by 514
COVID-19: ICU delirium management during SARS-CoV-2 pandemic
Kotfis, K., Williams Roberson, S., Wilson, J. E., Dabrowski, W., Pun, B. T., & Ely, E. W. (2020) · Critical Care · doi:10.1186/s13054-020-02882-x · Cited by 506
Analgesia and sedation in patients with ARDS
Chanques, G., Constantin, J.-M., Devlin, J. W., Ely, E. W., Fraser, G. L., Gélinas, C., Girard, T. D., Guérin, C., Jabaudon, M., Jaber, S., et al. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-06307-9 · Cited by 313
Self-citationNeurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms
Berger, M., Terrando, N., Smith, S. K., Browndyke, J. N., Newman, M. F., & Mathew, J. P. (2018) · Anesthesiology · doi:10.1097/aln.0000000000002194 · Cited by 256
Metadata
- Authors
- Vincent, J.-L., Shehabi, Y., Walsh, T. S., Pandharipande, P. P., Ball, J. A., Spronk, P., Longrois, D., Strøm, T., Conti, G., Funk, G.-C., Badenes, R., Mantz, J., Spies, C., & Takala, J.
- Venue
- Intensive Care Medicine
- Published
- 2016-04-13
- Volume
- 42
- Issue
- 6
- Pages
- 962-971
- ISSN
- 0342-4642 (ISSN-L)
- 1432-1238
- OpenAlex
- W2340638706
- Cited by
- 440
- References
- 70
- FWCI
- 33.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Comfort and patient-centred care without excessive sedation: the eCASH concept. https://app.cochat.ai/papers/10.1007/s00134-016-4297-4
- The paper
- Vincent, J.-L., Shehabi, Y., Walsh, T. S., Pandharipande, P. P., Ball, J. A., Spronk, P., Longrois, D., Strøm, T., Conti, G., Funk, G.-C., Badenes, R., Mantz, J., Spies, C., & Takala, J. (2016). Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive Care Medicine. https://doi.org/10.1007/s00134-016-4297-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
