Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: The LUNG SAFE study.

Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome

(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Chen, Y., Wang, L., Kang, Q., Zhang, X., Yu, G., Wan, X., Wang, J., & Zhu, K. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000477308 · Cited by 10,730

Acute Respiratory Distress Syndrome

Ards Definition Task Force (2012) · JAMA · doi:10.1001/jama.2012.5669 · Cited by 9,066

Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries.

Bellani, G., Laffey, J. G., Pham, T., Fan, E., Brochard, L., Esteban, A., Gattinoni, L., van Haren, F., Larsson, A., McAuley, D. F., et al. (2016) · JAMA · doi:10.1001/jama.2016.0291 · Cited by 5,766

Prone positioning in severe acute respiratory distress syndrome.

Guérin, C., Reignier, J., Richard, J.-C., Beuret, P., Gacouin, A., Boulain, T., Mercier, E., Badet, M., Mercat, A., Baudin, O., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1214103 · Cited by 4,040

Incidence and Outcomes of Acute Lung Injury

Rubenfeld, G. D., Caldwell, E., Peabody, E., Weaver, J., Martin, D. P., Neff, M., Stern, E. J., & Hudson, L. D. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050333 · Cited by 3,684

Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome.

Amato, M. B. P., Barbas, C. S. V., Medeiros, D. M., Magaldi, R. B., Schettino, G. P., Lorenzi-Filho, G., Kairalla, R. A., Deheinzelin, D., Munoz, C., Oliveira, R., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802053380602 · Cited by 3,654

Driving pressure and survival in the acute respiratory distress syndrome.

Amato, M. B. P., Meade, M. O., Slutsky, A. S., Brochard, L., Costa, E. L. V., Schoenfeld, D. A., Stewart, T. E., Briel, M., Talmor, D., Mercat, A., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmsa1410639 · Cited by 2,801

Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome

Papazian, L., Forel, J.-M., Gacouin, A., Penot-Ragon, C., Perrin, G., Loundou, A., Jaber, S., Arnal, J.-M., Perez, D., Seghboyan, J.-M., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1005372 · Cited by 2,432

Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome: Systematic Review and Meta-analysis

Briel, M., Meade, M., Mercat, A., Brower, R. G., Talmor, D., Walter, S. D., Slutsky, A. S., Pullenayegum, E., Zhou, Q., Cook, D., et al. (2010) · JAMA · doi:10.1001/jama.2010.218 · Cited by 1,467

ARDS clinical practice guideline 2021

Tasaka, S., Ohshimo, S., Takeuchi, M., Yasuda, H., Ichikado, K., Tsushima, K., Egi, M., Hashimoto, S., Shime, N., Saitô, O., et al. (2022) · Respiratory Investigation · doi:10.1016/j.resinv.2022.05.003 · Cited by 30

Driving Pressure for Ventilation of Patients with Acute Respiratory Distress Syndrome

Meier, A., Sell, R., & Malhotra, A. (2020) · Anesthesiology · doi:10.1097/aln.0000000000003195 · Cited by 30

Management of the patient with the open abdomen

Einav, S., Zimmerman, F. S., Tankel, J., & Léone, M. (2021) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000879 · Cited by 25

First Stabilize and then Gradually Recruit: A Paradigm Shift in Protective Mechanical Ventilation for Acute Lung Injury

Nieman, G. F., Kaczka, D. W., Andrews, P. L., Ghosh, A., Al-Khalisy, H., Camporota, L., Satalin, J. M., Herrmann, J., & Habashi, N. M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12144633 · Cited by 25

Low flow extracorporeal CO2 removal in ARDS patients: a prospective short-term crossover pilot study

Peperstraete, H., Eloot, S., Depuydt, P. O., Somer, F. M. J. J. D., Roosens, C. D. V. K., & Hoste, E. A. J. (2017) · BMC Anesthesiology · doi:10.1186/s12871-017-0445-9 · Cited by 25

Recent advances in understanding acute respiratory distress syndrome

Wohlrab, P., Kraft, F., Tretter, V. E., Ullrich, R., Markstaller, K., & Klein, K. U. (2018) · F1000Research · doi:10.12688/f1000research.11148.1 · Cited by 26

Continued under-recognition of acute respiratory distress syndrome after the Berlin definition: what is the solution?

Laffey, J. G., Pham, T. O., & Bellani, G. (2016) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000381 · Cited by 24

The Association Between Mechanical Power Within the First 24 Hours and ICU Mortality in Mechanically Ventilated Adult Patients With Acute Hypoxemic Respiratory Failure

von Düring, S., Liu, K., Munshi, L., Kim, S. J., Urner, M., Adhikari, N. K. J., Parhar, K. K. S., & Fan, E. (2025) · CHEST Journal · doi:10.1016/j.chest.2025.03.012 · Cited by 23

Diagnosis of acute respiratory distress syndrome (DARTS) by bedside exhaled breath octane measurements in invasively ventilated patients: protocol of a multicentre observational cohort study

Hagens, L. A., Heijnen, N. F. L., Smit, M. R., Verschueren, A. R. M., Nijsen, T. M. E., Geven, I., Schultz, M. J., Bergmans, D. C. J. J., Schnabel, R. M., & Bos, L. D. J. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-1384 · Cited by 23

Driving pressure of respiratory system and lung stress in mechanically ventilated patients with active breathing

Stamatopoulou, V., Akoumianaki, E., Vaporidi, K., Stamatopoulos, E., Kondili, Ε., & Georgopoulos, D. (2024) · Critical Care · doi:10.1186/s13054-024-04797-3 · Cited by 25

In vitro characterization of PrismaLung+: a novel ECCO2R device

Hospach, I., GOLDSTEIN, J. P., Harenski, K., Laffey, J. G., Pouchoulin, D., Raible, M., Votteler, S., & Storr, M. (2020) · Intensive Care Medicine Experimental · doi:10.1186/s40635-020-00301-7 · Cited by 23

Associations between changes in oxygenation, dead space and driving pressure induced by the first prone position session and mortality in patients with acute respiratory distress syndrome

van Meenen, D. M. P., Roozeman, J.-P., Neto, A. S., Pelosi, P. P., de Abreu, M. G., Horn, J., Cremer, O. L., Paulus, F., & Schultz, M. J. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.12.38 · Cited by 21

Tidal Volume Lowering by Instrumental Dead Space Reduction in Brain-Injured ARDS Patients: Effects on Respiratory Mechanics, Gas Exchange, and Cerebral Hemodynamics

Pitoni, S., D’Arrigo, S., Grieco, D. L., Idone, F. A., Santantonio, M. T., Giannatale, P. D., Ferrieri, A., Natalini, D., Eleuteri, D., Jonson, B., et al. (2020) · Neurocritical Care · doi:10.1007/s12028-020-00969-5 · Cited by 22

Clinical care for severe acute respiratory infection: toolkit: COVID-19 adaptation

Paraguassu, É. C., & Lacerda, J. D. P. (2022) · Brazilian Journal of Implantology and Health Sciences · doi:10.36557/2674-8169.2022v4n3p48-330 · Cited by 24

Low Tidal Volume Ventilation for Emergency Department Patients: A Systematic Review and Meta-Analysis on Practice Patterns and Clinical Impact*

Monnin, K. D., Terian, E., Yaegar, L. H., Pappal, R. D., Mohr, N. M., Roberts, B. W., Kollef, M. H., Palmer, C., Ablordeppey, E., & Fuller, B. M. (2022) · Critical Care Medicine · doi:10.1097/ccm.0000000000005459 · Cited by 22

Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts

the SOAP and ICON Investigators, Sakr, Y. L., François, B., Solé‐Violán, J., Kotfis, K., Jaschinski, U., Estella, Á., Léone, M., Jakob, S. M., Wittebole, X., et al. (2021) · Critical Care · doi:10.1186/s13054-020-03455-8 · Cited by 20

Death in hospital following ICU discharge: insights from the LUNG SAFE study

Madotto, F., McNicholas, B., Rezoagli, E., Pham, T. O., Laffey, J. G., Bellani, G., the LUNG SAFE Investigators, Pesenti, A., Laffey, J. G., Brochard, L. J., et al. (2021) · Critical Care · doi:10.1186/s13054-021-03465-0 · Cited by 20

Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?

Zochios, V., Yusuff, H. O., Antonini, M. V., Schmidt, M., Shekar, K., & for Protecting the Right Ventricle Network (PRORVnet) (2023) · ASAIO Journal · doi:10.1097/mat.0000000000001930 · Cited by 20

Personalized Positive End-Expiratory Pressure and Tidal Volume in Acute Respiratory Distress Syndrome: Bedside Physiology-Based Approach

Mauri, T. (2021) · Critical Care Explorations · doi:10.1097/cce.0000000000000486 · Cited by 20

Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials

Harrington, J. S., Schenck, E. J., Oromendia, C., Choi, A. M. K., & Siempos, I. Ι. (2018) · Journal of Critical Care · doi:10.1016/j.jcrc.2018.06.002 · Cited by 19

The handling oxygenation targets in the intensive care unit (HOT‐ICU) trial: Detailed statistical analysis plan

Schjørring, O. L., Klitgaard, T. L., Perner, A., Wetterslev, J., Lange, T., Keus, F., Laake, J. H., Morgan, M., Bäcklund, M., Siegemund, M., et al. (2020) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.13569 · Cited by 19

Epidemiology, ventilation management and outcomes of COVID–19 ARDS patients versus patients with ARDS due to pneumonia in the Pre–COVID era

van der Ven, F. L. I. M., Blok, S. G., Azevedo, L. C. P., Bellani, G., Botta, M., Estenssoro, E., Fan, E., Ferreira, J. C., Laffey, J. G., Martín‐Loeches, I., et al. (2024) · Respiratory Research · doi:10.1186/s12931-024-02910-2 · Cited by 18

The respiratory pressure—abdominal volume curve in a porcine model

Regli, A., Keulenaer, B. L. D., Singh, B., Hockings, L. E., Noffsinger, B., & van Heerden, P. V. (2017) · Intensive Care Medicine Experimental · doi:10.1186/s40635-017-0124-7 · Cited by 18

Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study

Laffey, C. M., Sheerin, R., Khazaei, O., McNicholas, B., Pham, T. O., Heunks, L. M. A., Bellani, G., Brochard, L. J., Tomescu, D. R., Simpkin, A. J., et al. (2025) · Annals of Intensive Care · doi:10.1186/s13613-025-01435-1 · Cited by 17

Stress, strain y potencia mecánica. ¿Es la ingeniería de materiales la respuesta para prevenir la lesión inducida por el ventilador?

Alapont, V. M. I., Aguar, M., & Villanueva, A. M. (2018) · Medicina Intensiva · doi:10.1016/j.medin.2018.06.008 · Cited by 17

Mechanical Ventilation during Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: A Narrative Review

Chiu, L., & Kao, K. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10214953 · Cited by 17

Expert perspectives on ECCO2R for acute hypoxemic respiratory failure: consensus of a 2022 European roundtable meeting

Combes, A., Auzinger, G. M., Camporota, L., Capellier, G., Consales, G., Couto, A. G., Dąbrowski, W., Davies, R., Demirkıran, O., Gómez, C. F., et al. (2024) · Annals of Intensive Care · doi:10.1186/s13613-024-01353-8 · Cited by 16

Effect of Automated Closed-loop ventilation versus convenTional VEntilation on duration and quality of ventilation in critically ill patients (ACTiVE) – study protocol of a randomized clinical trial

Botta, M., Tsonas, A. M., Sinnige, J. S., Dekker, A. D. B., Bindels, A. J. G. H., Ball, L., Battaglini, D., Brunetti, I., Buiteman‐Kruizinga, L. A., van der Heiden, P. L. J., et al. (2022) · Trials · doi:10.1186/s13063-022-06286-w · Cited by 17

Extracorporeal membrane oxygenation in patients with hematologic malignancies: a systematic review and meta-analysis

Sim, J. J. L., Mitra, S., Ling, R. R., Tan, C. S., Fan, B. E., MacLaren, G., & Ramanathan, K. R. (2022) · Annals of Hematology · doi:10.1007/s00277-022-04855-2 · Cited by 16

Mechanical ventilation in patients with acute respiratory distress syndrome: current status and future perspectives

Battaglini, D., Iavarone, I. G., Robba, C., Ball, L., Silva, P. L., & Rocco, P. R. M. (2023) · Expert Review of Medical Devices · doi:10.1080/17434440.2023.2255521 · Cited by 17

Donor ventilation parameters as predictors for length of mechanical ventilation after lung transplantation: Results of a prospective multicenter study

Benazzo, A., Schwarz, S., Frommlet, F., Sinn, K., Schweiger, T., Klikovits, T., Hoda, A. M., Moser, B., Matilla, J. R., Vámos, F. R., et al. (2020) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2020.10.008 · Cited by 16

Ultraprotective ventilation allowed by extracorporeal CO2 removal improves the right ventricular function in acute respiratory distress syndrome patients: a quasi-experimental pilot study

Goursaud, S., Valette, X., Dupeyrat, J., Daubin, C., & du Cheyron, D. (2021) · Annals of Intensive Care · doi:10.1186/s13613-020-00784-3 · Cited by 15

Prognostic value of disease severity and mechanical ventilation intensity in acute respiratory distress syndrome: analysis of the LUNG SAFE cohort

Rezoagli, E., Laffey, J. G., Madotto, F., Protti, A., Pham, T. O., Pesenti, A., Bellani, G., & Brochard, L. J. (2025) · European Respiratory Journal · doi:10.1183/13993003.00742-2025 · Cited by 16

Driving airway and transpulmonary pressure are correlated to VILI determinants during controlled ventilation

Pistillo, N., & Farina, O. H. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5092-1 · Cited by 16

Positive end-expiratory pressure adjusted for intra-abdominal pressure – A pilot study

Regli, A., Keulenaer, B. L. D., Palermo, A., & van Heerden, P. V. (2017) · Journal of Critical Care · doi:10.1016/j.jcrc.2017.10.012 · Cited by 15

Respiratory rate and peak inspiratory pressure, new targets from the LUNG SAFE study analysis or physiopathological artifacts?

Guervilly, C., Forel, J. M., & Papazian, L. (2017) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.02.45 · Cited by 15

Effect of Automated Closed-Loop Ventilation vs Protocolized Conventional Ventilation on Ventilator-Free Days in Critically Ill Adults

Sinnige, J. S., Buiteman‐Kruizinga, L. A., Horn, J., Paulus, F., Schultz, M. J., Neto, A. S., ACTiVE Investigators and the Protective Ventilation Network, Appel, R., Dekker, A. D. B., Bindels, A. J. G. H., et al. (2025) · JAMA · doi:10.1001/jama.2025.24384 · Cited by 14

Higher versus lower positive end-expiratory pressure in patients without acute respiratory distress syndrome: a meta-analysis of randomized controlled trials

Pettenuzzo, T., Boscolo, A., CASSAI, A. D., Sella, N., Zarantonello, F., Persona, P., Pasin, L., Landoni, G., & Navalesi, P. (2021) · Critical Care · doi:10.1186/s13054-021-03669-4 · Cited by 15

Future directions of lung‐protective ventilation strategies in acute respiratory distress syndrome

Hoshino, T., & Yoshida, T. (2024) · Acute Medicine & Surgery · doi:10.1002/ams2.918 · Cited by 15

Optimal plateau pressure for patients with acute respiratory distress syndrome: a protocol for a systematic review and meta-analysis with meta-regression

Yasuda, H., Nishimura, T., Kamo, T., Sanui, M., Nango, E., Abe, T., Takebayashi, T., Lefor, A. K., & Hashimoto, S. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-015091 · Cited by 15

COVID-19 pandemic: overview of protective-ventilation strategy in ARDS patients

Higny, J., Feye, F., & Forêt, F. (2020) · Acta Clinica Belgica · doi:10.1080/17843286.2020.1761162 · Cited by 15

Driving Pressure Is a Risk Factor for ARDS in Mechanically Ventilated Subjects Without ARDS

Roca, O., Peñuelas, Ó., Muriel, A., García-de-Acilu, M., Laborda, C., Sacanell, J., Riera, J., Raymondos, K., Du, B., Thille, A. W., et al. (2021) · Respiratory Care · doi:10.4187/respcare.08587 · Cited by 14

Lung failure after polytrauma with concomitant thoracic trauma in the elderly: an analysis from the TraumaRegister DGU®

Vollrath, J. T., Schindler, C. R., Marzi, İ., Lefering, R. L., Störmann, P., & the TraumaRegister, D. G. U. (2022) · World Journal of Emergency Surgery · doi:10.1186/s13017-022-00416-0 · Cited by 14

Invasive mechanical ventilation in patients with acute respiratory distress syndrome receiving extracorporeal support: a narrative review of strategies to mitigate lung injury

Zochios, V., Brodie, D., Shekar, K., Schultz, M. J., & Parhar, K. K. S. (2022) · Anaesthesia · doi:10.1111/anae.15806 · Cited by 16

Optimal Upper Limits of Plateau Pressure for Patients With Acute Respiratory Distress Syndrome During the First Seven Days: A Meta-Regression Analysis

Yasuda, H., Sanui, M., Nishimura, T., Kamo, T., Nango, E., Abe, T., Roberts, R., Takebayashi, T., Hashimoto, S., & Lefor, A. K. (2021) · Journal of Clinical Medicine Research · doi:10.14740/jocmr4390 · Cited by 12

ARDS and aging: TYMS emerges as a promising biomarker and therapeutic target

Li, G., Yan, K., Zhang, W., Pan, H., & Guo, P. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1365206 · Cited by 14

Sepsis 2019 – New Trends and Their Implications for Multiple Trauma Patients

Dickmann, P., & Bauer, M. W. (2019) · Zeitschrift für Orthopädie und Unfallchirurgie · doi:10.1055/a-0853-2054 · Cited by 14

Survival of COVID-19 Patients With Respiratory Failure is Related to Temporal Changes in Gas Exchange and Mechanical Ventilation

Ende, V., Singh, G. K., Babatsikos, I., Hou, W., Li, H., Thode, H. C., Singer, A. J., Duong, T. Q., & Richman, P. S. (2021) · Journal of Intensive Care Medicine · doi:10.1177/08850666211033836 · Cited by 13

Development and validation of a clinical risk model to predict the hospital mortality in ventilated patients with acute respiratory distress syndrome: a population-based study

Ye, W., Li, R., Liang, H., Huang, Y., Xu, Y., Li, Y., Ou, L., Mao, P., Liu, X., & Li, Y. (2022) · BMC Pulmonary Medicine · doi:10.1186/s12890-022-02057-0 · Cited by 12

Racial disparities in critical care: experience from the USA

Chertoff, J. (2017) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(17)30009-7 · Cited by 12

Case 19-2020: A 74-Year-Old Man with Acute Respiratory Failure and Unclear Goals of Care

Jacobsen, J. C., Tran, K. M., Jackson, V. A., & Rubin, E. B. (2020) · New England Journal of Medicine · doi:10.1056/nejmcpc2002419 · Cited by 12

Changes in ventilator settings and ventilation–induced lung injury in burn patients—A systematic review

Glas, G. J., Horn, J., van der Hoeven, S. M., Hollmann, M. W., Cleffken, B. I., Colpaert, K. E., Juffermans, N. P., Knape, P., Loef, B. G., Mackie, D. P., et al. (2019) · Burns · doi:10.1016/j.burns.2019.05.015 · Cited by 12

Incidence and Outcomes of Acute Respiratory Distress Syndrome in Brain-Injured Patients Receiving Invasive Ventilation: A Secondary Analysis of the ENIO Study

Taran, S., Stevens, R. D., Perrot, B., McCREDIE, V. A., Cinotti, R., Asehnoune, K., Pelosi, P. P., & Robba, C. (2023) · Journal of Intensive Care Medicine · doi:10.1177/08850666231194532 · Cited by 12

Guide to Lung-Protective Ventilation in Cardiac Patients

Rali, A. S., Tran, L. E., Balakrishna, A., Senussi, M. H., Kapur, N. K., Metkus, T. S., Tedford, R. J., & Lindenfeld, J. M. (2024) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2024.01.018 · Cited by 13

Reclassifying severity after 48 hours could better predict mortality in acute respiratory distress syndrome

Chiu, L., Lin, S., Liu, P., Chuang, L., Chang, C.-H., Hung, C., Li, S., Lee, C.-S., Wu, H.-P., Huang, C.-C., et al. (2020) · Therapeutic Advances in Respiratory Disease · doi:10.1177/1753466620936877 · Cited by 12

Severity of illness affecting the length of stay and outcomes in patients admitted to intensive care units, Iran, 2019

Setareh, M., Alavi, N. M., & Atoof, F. (2021) · Journal of Education and Health Promotion · doi:10.4103/jehp.jehp_780_20 · Cited by 11

Using real-time visualization system for data-driven decision support to achieve lung protective strategy: a retrospective observational study

Tseng, H.-Y., Chen, C., Lin, Y.-C., Chuang, M., Hsu, W., Hsiao, W. Y., Chen, T.-M., Wang, M.-T., Huang, W., Chen, C., et al. (2022) · Critical Care · doi:10.1186/s13054-022-04091-0 · Cited by 11

Clinical implications of the rheological theory in the prevention of ventilator-induced lung injury. Is mechanical power the solution?

Alapont, V. M. I., Carrascosa, M. A., & Villanueva, A. M. (2018) · Medicina Intensiva (English Edition) · doi:10.1016/j.medine.2018.06.005 · Cited by 11

Higher vs. Lower DP for Ventilated Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis

Chen, Z., Wei, X., Liu, G., Tai, Q., Zheng, D., Xie, W., Chen, L., Wang, G., Sun, J., Wang, S., et al. (2019) · Emergency Medicine International · doi:10.1155/2019/4654705 · Cited by 11

Echocardiographic Assessment of the Right Ventricle and Its Correlation with Patient Outcome in Acute Respiratory Distress Syndrome

Taha, A., Zaytoun, T., Eid, H., Baess, A. I., & Reweny, E. M. E. (2020) · Advances in respiratory medicine · doi:10.5603/arm.a2020.0153 · Cited by 11

Outcomes and risk factors for delayed-onset postoperative respiratory failure: a multi-center case-control study by the University of California Critical Care Research Collaborative (UC3RC)

Stocking, J. C., Drake, C., Aldrich, J. M., Ong, M. K., Amin, A., Marmor, R. A., Godat, L. N., Cannesson, M. P., Gropper, M. A., Romano, P. S., et al. (2022) · BMC Anesthesiology · doi:10.1186/s12871-022-01681-x · Cited by 11

Acute Kidney Injury Associated with Severe Leptospirosis: Fatal Re-Emerging Disease in Latin America

Osorio-Rodríguez, E., Rodelo-Barrios, D., Rebolledo-Maldonado, C., Polo-Barranco, A., Patiño-Patiño, J., Aldana-Roa, M., Sánchez-Daza, V., Sierra-Ordoñez, E., & Bettin-Martínez, A. (2024) · Kidney and Dialysis · doi:10.3390/kidneydial4020006 · Cited by 10

A preliminary cost-effectiveness analysis of lung protective ventilation with extra corporeal carbon dioxide removal (ECCO2R) in the management of acute respiratory distress syndrome (ARDS)

Ethgen, O., GOLDSTEIN, J. P., Harenski, K., Dessap, A. M., Morimont, P., Quintel, M., & Combes, A. (2021) · Journal of Critical Care · doi:10.1016/j.jcrc.2021.01.014 · Cited by 10

Establishment of a risk prediction model for prolonged mechanical ventilation after lung transplantation: a retrospective cohort study

Gao, P., Li, C., Wu, J., Zhang, P., Liu, X., Li, Y., Ding, J., Su, Y., Zhu, Y., He, W., et al. (2023) · BMC Pulmonary Medicine · doi:10.1186/s12890-023-02307-9 · Cited by 13

Bridging the critically ill patient with acute to chronic liver failure to liver transplantation

Fernández, J., Blasi, A., Hidalgo, E. L., & Karvellas, C. J. (2024) · American Journal of Transplantation · doi:10.1016/j.ajt.2024.03.026 · Cited by 12

Definitions, Epidemiology, Clinical Risk Factors, and Health Disparities in Acute Respiratory Distress Syndrome

Kang, M., & Kempker, J. A. (2019) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0039-1683884 · Cited by 10

Utilization and outcomes of extracorporeal CO 2 removal (ECCO 2 R): Systematic review and meta‐analysis of arterio‐venous and veno‐venous ECCO 2 R approaches

Yu, T. Z., Tatum, R. T., Saxena, A., Ahmad, D., Yost, C. C., Maynes, E. J., O’Malley, T. J., Massey, H. T., Swol, J., Whitson, B. A., et al. (2021) · Artificial Organs · doi:10.1111/aor.14130 · Cited by 10

Predictive value of computed tomography for short-term mortality in patients with acute respiratory distress syndrome: a systematic review

Hashimoto, H., Yamamoto, S., Nakagawa, H., Suido, Y., Sato, S., Tabata, E., Okamori, S., Yoshida, T., Andō, K., Yoshitake, S., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-13972-x · Cited by 10

Long term feasibility of ultraprotective lung ventilation with low-flow extracorporeal carbon dioxide removal in ARDS patients

Chiumello, D., Pozzi, T., Mereto, E., Fratti, I., Chiodaroli, E., Gattinoni, L., & Coppola, S. (2022) · Journal of Critical Care · doi:10.1016/j.jcrc.2022.154092 · Cited by 10

Acute Respiratory Failure and Pulmonary Complications in End-Stage Liver Disease

Wang, T. S., Barjaktarević, I., Chang, S. Y., & Qadir, N. (2018) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0038-1673638 · Cited by 12

Vaping-Induced Lung Disease — A Look Forward by Looking Back

Stanbrook, M. B., & Drazen, J. M. (2020) · New England Journal of Medicine · doi:10.1056/nejme2004876 · Cited by 10

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Sreedharan, J. K., & Alqahtani, J. S. (2018) · Indian Journal of Respiratory Care · doi:10.4103/ijrc.ijrc_12_18 · Cited by 9

Recruitment-to-inflation ratio for bedside PEEP selection in acute respiratory distress syndrome

Rosà, T., Bongiovanni, F., Michi, T., Mastropietro, C., Menga, L. S., PASCALE, G. D., Antonelli, M. M., & Grieco, D. L. (2024) · Minerva Anestesiologica · doi:10.23736/s0375-9393.24.17982-5 · Cited by 9

Predictive validity of the sequential organ failure assessment score for mortality in patients with acute respiratory distress syndrome in Vietnam

Co, D. X., Dang, T. Q., Luong, C. Q., Manabe, T., Nguyen, M. H., Pham, D. T., Pham, Q. T., Vu, T. T., Truong, H. T., Nguyen, H. H., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-92199-y · Cited by 11

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Alapont, V. M. I., Carrascosa, M. A., & Villanueva, A. M. (2018) · Medicina Intensiva (English Edition) · doi:10.1016/j.medine.2018.06.004 · Cited by 9

Treatment for acute respiratory distress syndrome in adults: a narrative review of phase 2 and 3 trials

Battaglini, D., Robba, C., Pelosi, P. P., & Rocco, P. R. M. (2022) · Expert Opinion on Emerging Drugs · doi:10.1080/14728214.2022.2105833 · Cited by 9

Immunocompromised Children With Acute Respiratory Distress Syndrome Possess a Distinct Circulating Inflammatory Profile

Nguyen, J., Thompson, J. M., Balcarcel, D. R., Alder, M. N., McKeone, D. J., Halstead, E. S., Rowan, C. M., Lindell, R. B., & Yehya, N. (2023) · Critical Care Explorations · doi:10.1097/cce.0000000000000844 · Cited by 9

Factors influencing the transition phase in acute respiratory distress syndrome: an observational cohort study

Haudebourg, A.-F., Chantelot, L., Nemlaghi, S., Haudebourg, L., Labedade, P., Boujelben, M. A., Voiriot, G., Dessap, A. M., Fartoukh, M. S., & Carteaux, G. (2025) · Annals of Intensive Care · doi:10.1186/s13613-025-01484-6 · Cited by 8

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Tetaj, N., Capecchi, G., Rubino, D., Stazi, G. V., Cingolani, E., Lesci, A., Segreti, A., Grigioni, F., & Bocci, M. G. (2026) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd13010054 · Cited by 8

Driving pressure-guided ventilation versus protective lung ventilation in ARDS patients: A prospective randomized controlled study

Hamama, K., Fathy, S. M., AbdAlrahman, R. S., Alsherif, S. E.-D. I., & Ahmed, S. A. (2021) · Egyptian Journal of Anaesthesia · doi:10.1080/11101849.2021.1930401 · Cited by 8

Taraxasterol Inhibits Hyperactivation of Macrophages to Alleviate the Sepsis-induced Inflammatory Response of ARDS Rats

Bu, C., Wang, R., Wang, Y., Lu, B., He, S., & Zhao, X. (2022) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-022-01092-2 · Cited by 8

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Grieco, D. L., Costa, E. L. V., & Nolan, J. P. (2022) · Intensive Care Medicine · doi:10.1007/s00134-022-06779-x · Cited by 8

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Barakat, C., Fritsch, S. J., Riedel, M., & Brynjólfsson, S. (2021) · International Convention on Information and Communication Technology, Electronics and Microelectronics · doi:10.23919/mipro52101.2021.9596840 · Cited by 8

A reduced glycine-to-taurine ratio of conjugated serum bile acids signifies an adaptive mechanism and is an early marker of outcome in acute respiratory distress syndrome

Harnisch, L.-O., Mihaylov, D., Bein, T., Apfelbacher, C., Moerer, O., & Quintel, M. (2022) · Internal and Emergency Medicine · doi:10.1007/s11739-022-03152-0 · Cited by 7

The Safety and Efficiency of Addressing ARDS Using Stem Cell Therapies in Clinical Trials

Rezoagli, E., Murphy, E. J., Laffey, J. G., & O’Toole, D. P. (2019) · Springer eBooks · doi:10.1007/978-3-030-29403-8_12 · Cited by 7

Tidal volume according to the 4-point sealing forces of a bag-valve-mask: an adult respiratory arrest simulator-based prospective, descriptive study

Uhm, D.-C., & Kim, A. (2021) · BMC Emergency Medicine · doi:10.1186/s12873-021-00451-1 · Cited by 7

Extracorporeal Membrane Oxygenation in Immunocompromised Patients With Acute Respiratory Distress Syndrome—A Retrospective Cohort Study

Cheng, C.-F., Chen, Y.-Y., Shih, M.-C., Huang, Y.-M., Tseng, L.-J., Lai, C., Lan, T.-Y., Lu, C.-H., Hsieh, S.-C., Li, K.-J., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.755147 · Cited by 9

Ventilation practices in burn patients—an international prospective observational cohort study

Glas, G. J., Horn, J., Hollmann, M. W., Preckel, B., Colpaert, K. E., Malbrain, M. L. N. G., Neto, A. S., Asehnoune, K., de Abreu, M. G., Martín‐Loeches, I., et al. (2021) · Burns & Trauma · doi:10.1093/burnst/tkab034 · Cited by 10

Extracorporeal membrane oxygenation in immunocompromised patients with acute respiratory failure: A retrospective cohort study

Tian, Y., Gu, S., Huang, X., Li, C., Zhang, Y., Xia, J., Feng, Y., Yu, X., Cai, Y., Wu, X., et al. (2023) · The Clinical Respiratory Journal · doi:10.1111/crj.13674 · Cited by 7

Effect of decreasing respiratory rate on the mechanical power of ventilation and lung injury biomarkers: a randomized cross-over clinical study in COVID-19 ARDS patients

Damiani, L. F., Basoalto, R., Oviedo, V., Alegría, L., Soto, D., Bachmann, M. C., Jalil, Y., Santis, C., Carpio, D., Ulloa, R., et al. (2025) · Intensive Care Medicine Experimental · doi:10.1186/s40635-025-00782-4 · Cited by 6

Patient characteristics, management and outcomes in a Nordic subset of the “large observational study to understand the global impact of severe acute respiratory failure” ( LUNG SAFE ) study

Laake, J. H., Småstuen, M. C., Møller, M. H., Larsson, A., Aslam, T. N., Hofsø, K., Pham, T. O., Fan, E., Bellani, G., Laffey, J. G., et al. (2022) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.14069 · Cited by 5

Implicaciones clínicas de la teoría reológica en la prevención de la lesión pulmonar inducida por el ventilador. ¿Es la potencia mecánica la solución?

Alapont, V. M. I., Aguar, M., & Villanueva, A. M. (2018) · Medicina Intensiva · doi:10.1016/j.medin.2018.06.005 · Cited by 6

Assessment of respiratory support decision and the outcome of invasive mechanical ventilation in severe COVID-19 with ARDS

Cai, S., Zhu, F., Hu, H., Xiang, H., Wang, D., Wang, J., Li, L., Yang, X., Qin, A., Rao, X., et al. (2022) · Journal of Intensive Medicine · doi:10.1016/j.jointm.2021.12.003 · Cited by 6

Klug-entscheiden-Empfehlungen in der internistischen Intensivmedizin

Rießen, R., Kluge, S., Janssens, U., Kierdorf, H., Bodmann, K. ‐., Busch, H.-J., John, S., & Möckel, M. (2017) · Der Internist · doi:10.1007/s00108-017-0250-z · Cited by 6

Acute life-threatening hypoxemia during mechanical ventilation

Piraino, T., & Fan, E. (2017) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000459 · Cited by 6

Rheological Theory Applied to Mechanical Ventilation in Acute Respiratory Distress Syndrome: A New Paradigm for Understanding and Preventing Ventilator-Induced Lung Injury

Medina, A., Guerra, P. D. V., Ortiz, J. R. V., & Alapont, V. M. I. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14186544 · Cited by 5

Impact of Alcohol Misuse on Requirements for Critical Care Services and Development of Hospital Delirium in Patients With COVID-19 pneumonia

Jolley, S. E., Mowry, C. J., Erlandson, K. M., Wilson, M. P., & Burnham, E. L. (2023) · Critical Care Explorations · doi:10.1097/cce.0000000000000829 · Cited by 5

Perioperative Ventilation in Neurosurgical Patients: Considerations and Challenges

Iavarone, I. G., Rocco, P. R. M., Silva, P. L., Taran, S., Wahlster, S., Schultz, M. J., Patroniti, N. A., & Robba, C. (2024) · Current anesthesiology reports · doi:10.1007/s40140-024-00644-x · Cited by 5

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome: Propensity Score Matching

Chiu, L., Chuang, L., Leu, S., Lin, Y., Chang, C., Li, H.-H., Tsai, F., Chang, C., Hung, C., Lin, S., et al. (2021) · Membranes · doi:10.3390/membranes11060393 · Cited by 5

High-Fidelity Intelligence Ventilator to Help Infect with COVID-19 Based on Artificial Intelligence

Mabrouki, J., Azrour, M., Dhiba, D., & Hajjaji, S. E. (2021) · Algorithms for intelligent systems · doi:10.1007/978-981-16-1574-0_4 · Cited by 5

Modifiable risk factors and the role of driving pressure in acute respiratory distress syndrome

Keeley, J. A., & Kim, D. Y. (2017) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.03.140

Potentially modifiable ventilatory factors contributing to outcome in patients with pulmonary and extrapulmonary ARDS — An individual patient data analysis

Dorland, G. A., Blok, S. G., Swart, P., van der Ven, F. L. I. M., Hollmann, M. W., Azevedo, L. C. P., Bellani, G., Botta, M., Estenssoro, E., Fan, E., et al. (2026) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2025.112120 · Cited by 1

Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT

Simonis, F. D., Barbas, C. S. V., Artigas, A., Canet, J., Determann, R. M., Anstey, J. R., Hedenstierna, G., Hemmes, S. N. T., Hermans, G., Hiesmayr, M., et al. (2018) · Annals of Intensive Care · doi:10.1186/s13613-018-0385-7 · Cited by 40

ARDS: Risikofaktoren für die Sterblichkeit sind teilweise modifizierbar

(2017) · Journal Club AINS · doi:10.1055/s-0042-122697

Reduced mortality in association with the acute respiratory distress syndrome (ARDS)

Abel, S. J. C., Finney, S. J., Brett, S. J., Keogh, B. F., Morgan, C., & Evans, T. W. (1998) · Thorax · doi:10.1136/thx.53.4.292 · Cited by 231