The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study
Open accessAbstract
Purpose Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed to determine the relationship between SARS-CoV-2 pneumonia, as compared to influenza pneumonia or no viral infection, and the incidence of VA-LRTI. Methods Multicenter retrospective European cohort performed in 36 ICUs. All adult patients receiving invasive mechanical ventilation > 48 h were eligible if they had: SARS-CoV-2 pneumonia, influenza pneumonia, or no viral infection at ICU admission. VA-LRTI, including ventilator-associated tracheobronchitis (VAT) and ventilator-associated pneumonia (VAP), were diagnosed using clinical, radiological and quantitative microbiological criteria. All VA-LRTI were prospectively identified, and chest-X rays were analyzed by at least two physicians. Cumulative incidence of first episodes of VA-LRTI was estimated using the Kalbfleisch and Prentice method, and compared using Fine-and Gray models. Results 1576 patients were included (568 in SARS-CoV-2, 482 in influenza, and 526 in no viral infection groups). VA-LRTI incidence was significantly higher in SARS-CoV-2 patients (287, 50.5%), as compared to influenza patients (146, 30.3%, adjusted sub hazard ratio (sHR) 1.60 (95% confidence interval (CI) 1.26 to 2.04)) or patients with no viral infection (133, 25.3%, adjusted sHR 1.7 (95% CI 1.2 to 2.39)). Gram-negative bacilli were responsible for a large proportion (82% to 89.7%) of VA-LRTI, mainly Pseudomonas aeruginosa , Enterobacter spp., and Klebsiella spp. Conclusions The incidence of VA-LRTI is significantly higher in patients with SARS-CoV-2 infection, as compared to patients with influenza pneumonia, or no viral infection after statistical adjustment, but residual confounding may still play a role in the effect estimates.
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Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
Ackermann, M., Verleden, S. E., Kuehnel, M., Haverich, A., Welte, T., Laenger, F., Vanstapel, A., Werlein, C., Stark, H., Tzankov, A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2015432 · Cited by 5,613
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Ventilator-associated Pneumonia
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Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization
Zuo, T., Zhang, F., Lui, G. C. Y., Yeoh, Y. K., Li, A. Y. L., Zhan, H., Wan, Y., Chung, A. C. K., Cheung, C. P., Chen, N., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.05.048 · Cited by 1,537
The Analysis of Failure Times in the Presence of Competing Risks
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Ventilator-associated pneumonia in adults: a narrative review
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Badulak, J., Antonini, M. V., Stead, C. M., Shekerdemian, L., Raman, L., Paden, M. L., Agerstrand, C., Bartlett, R. H., Barrett, N., Combes, A., et al. (2021) · ASAIO Journal · doi:10.1097/mat.0000000000001422 · Cited by 404
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Metadata
- Authors
- Rouzé, A., Martin-Loeches, I., Povoa, P., Makris, D., Artigas, A., Bouchereau, M., Lambiotte, F., Metzelard, M., Cuchet, P., Boulle Geronimi, C., Labruyere, M., Tamion, F., Nyunga, M., Luyt, C.-E., Labreuche, J., Pouly, O., Bardin, J., Saade, A., Asfar, P., Baudel, J.-L., Beurton, A., Garot, D., Ioannidou, I., Kreitmann, L., Llitjos, J.-F., Magira, E., Mégarbane, B., Meguerditchian, D., Moglia, E., Mekontso-Dessap, A., Reignier, J., Turpin, M., Pierre, A., Plantefeve, G., Vinsonneau, C., Floch, P.-E., Weiss, N., Ceccato, A., Torres, A., Duhamel, A., Nseir, S., on behalf of the coVAPid study Group, Favory, R., Preau, S., Jourdain, M., Poissy, J., Bouras, C., Saint Leger, P., Fodil, H., Aptel, F., Van Der Linden, T., Thille, A. W., Azoulay, E., Pène, F., Razazi, K., Bagate, F., Contou, D., Voiriot, G., Thevenin, D., Guidet, B., Le Guennec, L., Kouatchet, A., Ehrmann, S., Brunin, G., Morawiec, E., Boyer, A., Argaud, L., Voicu, S., Nieszkowska, A., Kowalski, B., Goma, G., Diaz, E., Morales, L., Tsolaki, V., Gtavriilidis, G., Mentzelopoulos, S. D., Nora, D., Boyd, S., Coelho, L., Maizel, J., Du Cheyron, D., Imouloudene, M., Quenot, J.-P., Guilbert, A., & Cilloniz, C.
- Venue
- Intensive Care Medicine
- Published
- 2021-01-03
- Volume
- 47
- Issue
- 2
- Pages
- 188-198
- ISSN
- 0342-4642 (ISSN-L)
- 1432-1238
- OpenAlex
- W3118419263
- Cited by
- 382
- References
- 28
- FWCI
- 55.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rouzé, A., Martin-Loeches, I., Povoa, P., Makris, D., Artigas, A., Bouchereau, M., Lambiotte, F., Metzelard, M., Cuchet, P., Boulle Geronimi, C., Labruyere, M., Tamion, F., Nyunga, M., Luyt, C.-E., Labreuche, J., Pouly, O., Bardin, J., Saade, A., Asfar, P., . . . Cilloniz, C. (2021). Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study. Intensive Care Medicine. https://doi.org/10.1007/s00134-020-06323-9
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