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Cited by 275

The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.

Estrogen receptors and human disease: an update

Open access
Burns, Katherine A., Korach, Kenneth S.·2012·Archives of Toxicology

Abstract

A myriad of physiological processes in mammals are influenced by estrogens and the estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread role for estrogen in normal human physiology, it is not surprising that estrogen is implicated in the development or progression of a number of diseases. In this review, we are giving a 5-year update of the literature regarding the influence of estrogens on a number of human cancers (breast, ovarian, colorectal, prostate, and endometrial), endometriosis, fibroids, and cardiovascular disease. A large number of sophisticated experimental studies have provided insights into human disease, but for this review, the literature citations were limited to articles published after our previous review (Deroo and Korach in J Clin Invest 116(3):561–570, 2006) and will focus in most cases on human data and clinical trials. We will describe the influence in which estrogen’s action, through one of or both of the ERs, mediates the aforementioned human disease states.

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Metadata

Authors
Burns, K. A., & Korach, K. S.
Venue
Archives of Toxicology
Published
2012-05-31
Volume
86
Issue
10
Pages
1491-1504
ISSN
  • 0340-5761 (ISSN-L)
  • 1432-0738
OpenAlex
W2038933398
Cited by
275
References
154
FWCI
12.05
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Estrogen receptors and human disease: an update. https://app.cochat.ai/papers/10.1007/s00204-012-0868-5
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Burns, K. A., & Korach, K. S. (2012). Estrogen receptors and human disease: an update. Archives of Toxicology. https://doi.org/10.1007/s00204-012-0868-5

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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