Fluvoxamine, melatonin and COVID-19
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Fluvoxamine stimulates the sigma-1 receptor to reduce inflammatory response and nearly triples nocturnal plasma melatonin levels.
“Fluvoxamine stimulates the sigma-1 receptor to reduce inflammatory response, but it also nearly triples nocturnal plasma levels of melatonin [53].”
From Overview of sleep management during COVID-19. (2022) · cites this paper as [53]
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Cites
Lenze, E. J., Mattar, C., Zorumski, C. F., Stevens, A., Schweiger, J., Nicol, G. E., Miller, J. P., Yang, L., Yingling, M., Avidan, M. S., et al. (2020) · JAMA · doi:10.1001/jama.2020.22760 · Cited by 495 · see citing works
von Bahr, C., Ursing, C., Yasui, N., Tybring, G., Bertilsson, L., & Röjdmark, S. (2000) · European Journal of Clinical Pharmacology · doi:10.1007/s002280050729 · Cited by 107 · see citing works
Cardinali, D. P., Brown, G. M., Reiter, R. J., & Pandi-Perumal, S. R. (2020) · Sleep and Vigilance · doi:10.1007/s41782-020-00111-7 · Cited by 79 · see citing works
Noise and Light Pollution in the Hospital: A Call for Action
Kamdar, B. B., Martin, J. L., & Needham, D. M. (2017) · Journal of Hospital Medicine · doi:10.12788/jhm.2838 · Cited by 23 · see citing works
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Overview of sleep management during COVID-19.
Becker, P. M. (2022) · Sleep Medicine · doi:10.1016/j.sleep.2021.04.024 · Cited by 51 · see citing works
“Fluvoxamine stimulates the sigma-1 receptor to reduce inflammatory response, but it also nearly triples nocturnal plasma levels of melatonin [53].”
Background
- Authors
- Anderson, G. M.
- Affiliations
- Yale University (US)
- Corresponding author
- Anderson, George M.
- ORCID
- Anderson, George M.
- Venue
- Psychopharmacology
- Published
- 2021-01-04
- Volume
- 238
- Issue
- 2
- Pages
- 611-611
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- PMC
- PMC7779245
- OpenAlex
- W3120231206
- Cited by
- 21
- References
- 4
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 6 · 2021: 11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychopharmacology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- fluvoxamine, melatonin, COVID-19 pandemic, SARS-CoV-2, selective serotonin reuptake inhibitors, antiviral activity
- MeSH terms
- Clinical Deterioration, COVID-19, SARS-CoV-2, Humans, Melatonin, Outpatients, Fluvoxamine
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