Cited by 743Pesticide Residue Analysis and SafetyMass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry Studies

LC–high resolution MS in environmental analysis: from target screening to the identification of unknowns

Open access
Krauss, Martin, Singer, Heinz, Hollender, Juliane·2010·Analytical and Bioanalytical Chemistry

Abstract

This article provides an overview of the state-of-the-art and future trends of the application of LC-high resolution mass spectrometry to the environmental analysis of polar micropollutants. Highly resolved and accurate hybrid tandem mass spectrometry such as quadrupole/time-of-flight and linear ion trap/orbitrap technology allows for a more reliable target analysis with reference standards, a screening for suspected analytes without reference standards, and a screening for unknowns. A reliable identification requires both high resolving power and high mass spectral accuracy to increase selectivity against the matrix background and for a correct molecular formula assignment to unknown compounds. For the identification and structure elucidation of unknown compounds within a reasonable time frame and with a reasonable soundness, advanced automated software solutions as well as improved prediction systems for theoretical fragmentation patterns, retention times, and ionization behavior are needed.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s00216-010-3608-9

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. Hollender J, Singer H, Hernando D, Kosjek T, Heath E (2009) In: Kassinos D, Kümmerer K, Bester K (eds) Xenobiotics in the urban water cycle: mass flows, environmental processes, mitiga- tion and treatment strategies, Springer, Dordrecht, pp 195-211

Cited by

Sorted by citations

Authors
Krauss, M., Singer, H., & Hollender, J.
Affiliations
Swiss Federal Institute of Aquatic Science and Technology (CH)
Corresponding author
Singer, Heinz
Venue
Analytical and Bioanalytical Chemistry
Published
2010-03-16
Volume
397
Issue
3
Pages
943-951
ISSN
  • 1618-2642 (ISSN-L)
  • 1618-2650
OpenAlex
W2021828609
Cited by
743
References
35
Citations by year
2026: 22 · 2025: 32 · 2024: 38 · 2023: 44 · 2022: 61 · 2021: 55 · 2020: 50 · 2019: 51 · 2018: 72 · 2017: 59 · 2016: 57 · 2015: 71 · 2014: 40 · 2013: 36 · 2012: 22
FWCI
42.62
Type
journal article
Language
en
Open access
Locations
  • Analytical and Bioanalytical Chemistry (publishedVersion)
  • PubMed (publishedVersion)
  • reroDoc Digital Library (submittedVersion)
  • DORA Eawag (Swiss Federal Institute of Aquatic Science and Technology (Eawag)) (submittedVersion, other-oa)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Pesticide Residue Analysis and Safety
  • Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
Keywords
environmental analysis, target screening, unknown compound identification, quadrupole time-of-flight, molecular formula assignment, structure elucidation, retention time prediction, herbicides, linuron, soil extracts

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review