The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Current challenges in compound-specific stable isotope analysis of environmental organic contaminants
Open accessAbstract
AbstractCompound-specific stable-isotope analysis (CSIA) has greatly facilitated assessment of sources and transformation processes of organic pollutants. Multielement isotope analysis is one of the most promising applications of CSIA because it even enables distinction of different transformation pathways. This review introduces the essential features of continuous-flow isotope-ratio mass spectrometry (IRMS) and highlights current challenges in environmental analysis as exemplified for the isotopes of nitrogen, hydrogen, chlorine, and oxygen. Strategies and recent advances to enable isotopic measurements of polar contaminants, for example pesticides or pharmaceuticals, are discussed with special emphasis on possible solutions for analysis of low concentrations of contaminants in environmental matrices. Finally, we discuss different levels of calibration and referencing and point out the urgent need for compound-specific isotope standards for gas chromatography–isotope-ratio mass spectrometry (GC–IRMS) of organic pollutants. FigureCompound-specific isotope analysis of environmental contaminants: chromatographic separation is followed by online conversion to a suitable measurement gas (M) and subsequent isotope ratio mass spectrometry. Current challenges in the field concern the analysis of multiple elements (C, H, N, O, Cl) in polar compounds, at low concentrations and in the presence of matrix interferences. An urgent need exists for contaminant-specific reference materials.
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Cites
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Referencing strategies and techniques in stable isotope ratio analysis
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New Guidelines for δ 13 C Measurements
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Self-citationNormalization of measured stable isotopic compositions to isotope reference scales – a review
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Cited by
Huntscha, S., Hofstetter, T. B., Schymanski, E. L., Spahr, S., & Hollender, J. (2014) · Environmental Science & Technology · doi:10.1021/es405694z · Cited by 140
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Metadata
- Authors
- Elsner, M., Jochmann, M. A., Hofstetter, T. B., Hunkeler, D., Bernstein, A., Schmidt, T. C., & Schimmelmann, A.
- Venue
- Analytical and Bioanalytical Chemistry
- Published
- 2012-02-03
- Volume
- 403
- Issue
- 9
- Pages
- 2471-2491
- ISSN
- 1618-2642 (ISSN-L)
- 1618-2650
- OpenAlex
- W1994146779
- Cited by
- 276
- References
- 108
- FWCI
- 21.98
- Type
- journal article
- Language
- en
- Open access
- green
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