The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism
Open accessAbstract
Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the corresponding genotype. The analysis can decompose the intricate metabolic network comprised of highly interconnected reactions into uniquely organized pathways. These pathways consisting of a minimal set of enzymes that can support steady state operation of cellular metabolism represent independent cellular physiological states. Such pathway definition provides a rigorous basis to systematically characterize cellular phenotypes, metabolic network regulation, robustness, and fragility that facilitate understanding of cell physiology and implementation of metabolic engineering strategies. This mini-review aims to overview the development and application of elementary mode analysis as a metabolic pathway analysis tool in studying cell physiology and as a basis of metabolic engineering.
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Cited by
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Metabolic network modeling of microbial communities
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Advances in metabolic modeling of oleaginous microalgae
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Metadata
- Authors
- Trinh, C. T., Wlaschin, A., & Srienc, F.
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2009-01
- Volume
- 81
- Issue
- 5
- Pages
- 813-826
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2093241068
- Cited by
- 294
- References
- 89
- FWCI
- 7.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Trinh, C. T., Wlaschin, A., & Srienc, F. (2009). Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-008-1770-1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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