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Predictors for moderate to severe acute postoperative pain after total hip and knee replacement
Open accessAbstract
Purpose The ability to identify and focus care to patients at higher risk of moderate to severe postoperative pain should improve analgesia and patient satisfaction, and may affect reimbursement. We undertook this multi-centre cross-sectional study to identify preoperative risk factors for moderate to severe pain after total hip (THR) and knee (TKR) replacement. Methods A total of 897 patients were identified from electronic medical records. Preoperative information and anaesthetic technique was gained by retrospective chart review. The primary outcomes were moderate to severe pain (pain score ≥ 4/10) at rest and with activity on postoperative day one. Logistic regression was performed to identify predictors for moderate to severe pain. Results Moderate to severe pain was reported by 20 % at rest and 33 % with activity. Predictors for pain at rest were female gender (OR 1.10 with 95 % CI 1.01-1.20), younger age (0.96, 0.94-0.99), increased BMI (1.02, 1.01-1.03), TKR vs. THR (3.21, 2.73-3.78), increased severity of preoperative pain at the surgical site (1.15, 1.03-1.30), preoperative use of opioids (1.63, 1.32-2.01), and general anaesthesia (8.51, 2.13-33.98). Predictors for pain with activity were TKR vs. THR (1.42, 1.28-1.57), increased severity of preoperative pain at the surgical site (1.11, 1.04-1.19), general anaesthesia (9.02, 3.68-22.07), preoperative use of anti-convulsants (1.78, 1.32-2.40) and anti-depressants (1.50, 1.08-2.80), and prior surgery at the surgical site (1.28, 1.05-1.57). Conclusions Our findings provide clinical guidance for preoperative stratification of patients for more intensive management potentially including education, nursing staffing, and referral to specialised pain management.
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“Since its publication was nearly a decade ago, many additional studies have been published with improved methodological rigour;21–24 thus, providing a new opportunity to provide an updated summary of the literature and to generate pooled estimates of risk.”
From Preoperative predictors of poor acute postoperative pain control: a systematic review and meta-analysis (2019) · cites this paper as [23]
In the citing paper
“The use of preoperative analgesia, especially opioid therapy, has been linked to poor postoperative pain control in numerous studies.23 68”
From Preoperative predictors of poor acute postoperative pain control: a systematic review and meta-analysis (2019) · cites this paper as [23]
In the citing paper
“This may be due to greater preoperative severity of pain, opioid-induced hyperalgesia and central or peripheral sensitisation to pre-existing nociception.23 69”
From Preoperative predictors of poor acute postoperative pain control: a systematic review and meta-analysis (2019) · cites this paper as [23]
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Cites
Projections of Primary and Revision Hip and Knee Arthroplasty in the United States from 2005 to 2030
Kurtz, S. M., Ong, K. L., Lau, E., Mowat, F. S., & Halpern, M. T. (2007) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.f.00222 · Cited by 8,714
Aiken, L. H., Sermeus, W., den Heede, K. V., Sloane, D. M., Busse, R., McKee, M., Bruyneel, L., Rafferty, A. M., Griffiths, P., Moreno‐Casbas, T., et al. (2012) · BMJ · doi:10.1136/bmj.e1717 · Cited by 2,279
Opioid-induced Hyperalgesia: A Qualitative Systematic Review
Angst, M. S., & Clark, J. D. (2006) · Anesthesiology · doi:10.1097/00000542-200603000-00025 · Cited by 1,188
Predictors of Postoperative Pain and Analgesic Consumption: A Qualitative Systematic Review
Ip, H. Y. V., Abrishami, A., Peng, P. W. H., Wong, J., & Chung, F. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181aae87a · Cited by 1,055
Gerbershagen, H. J., Rothaug, J., Kalkman, C. J., & Meissner, W. (2011) · British Journal of Anaesthesia · doi:10.1093/bja/aer195 · Cited by 527
Chronic pain following total hip arthroplasty: a nationwide questionnaire study
Nikolajsen, L., Brandsborg, B., Lucht, U., Jensen, T. S., & Kehlet, H. (2006) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2006.00976.x · Cited by 279
Liu, S. S., & Wu, C. L. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000278089.16848.1e · Cited by 276
Self-citationDoes Regional Anesthesia Improve Outcome After Total Knee Arthroplasty?
Macfarlane, A. J. R., Prasad, G. A., Chan, V. W. S., & Brull, R. (2009) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-008-0666-9 · Cited by 203
Does regional anaesthesia improve outcome after total hip arthroplasty? A systematic review
Macfarlane, A. J. R., Prasad, G. A., Chan, V. W. S., & Brull, R. (2009) · British Journal of Anaesthesia · doi:10.1093/bja/aep208 · Cited by 197
Liu, S. S., Buvanendran, A., Rathmell, J. P., Sawhney, M., Bae, J. J., Moric, M. M., Perros, S., Pope, A. J., Poultsides, L. A., Valle, C. J. D., et al. (2012) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0b013e318251b688 · Cited by 162
Self-citationEasily adoptable total joint arthroplasty program allows discharge home in two days
Raphael, M. J., Jaeger, M. T., & van Vlymen, J. (2011) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-011-9565-8 · Cited by 136
Clarke, H. A., PEREIRA, S., Kennedy, D. M., Andrion, J. J., Mitsakakis, N., Gollish, J. D., Katz, J. D., & Kay, J. C. (2009) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2009.02039.x · Cited by 122
Recent Advances in Multimodal Analgesia
Young, A., & Buvanendran, A. (2012) · Anesthesiology Clinics · doi:10.1016/j.anclin.2011.12.002 · Cited by 116
Self-citationMei, W., Seeling, M., Franck, M., Radtke, F. M., Brantner, B., Wernecke, K., & Spies, C. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2009.03.009 · Cited by 96
Prediction of postoperative pain using path analysis in older patients
Kinjo, S., Sands, L. P., Lim, E., Paul, S., & Leung, J. M. (2011) · Journal of Anesthesia · doi:10.1007/s00540-011-1249-6 · Cited by 62
Lee, A. S. Y., Chan, S. K. C., Chen, P. P., Gin, T., Lau, A. S. C., & Chiu, C. H. (2010) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181ed1317 · Cited by 51
Yen, C.-R., Tsou, M., Mandell, M. S., Chan, C.-T., Chan, K.-H., Chen, T. H.-H., & Chang, K.-Y. (2010) · Anesthesiology · doi:10.1097/aln.0b013e3181cbd1f3 · Cited by 43
The World Health Organization Paves the Way for Action to Free People from the Shackles of Pain
Scholten, W., Nygren-Krug, H., & Zucker, H. A. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000267542.72315.34 · Cited by 40
The Effectiveness of Warfarin Dosing from a Nomogram Compared with House Staff Dosing
Asnis, P. D., Gardner, M. J., Ranawat, A. S., Leitzes, A. H., Peterson, M. G. E., & Bass, A. R. (2007) · The Journal of Arthroplasty · doi:10.1016/j.arth.2006.03.006 · Cited by 34
Philips, B. D., Liu, S. S., Wukovits, B., Boettner, F., Waldman, S. A., Liguori, G. A., Goldberg, S., Goldstein, L., Melia, J., Hare, M. E., et al. (2009) · HSS Journal® The Musculoskeletal Journal of Hospital for Special Surgery · doi:10.1007/s11420-009-9135-6 · Cited by 15
Self-citationBinhas, M., Roudot‐Thoraval, F., Thominet, D., Maison, P., & Marty, J. (2008) · European Journal of Anaesthesiology · doi:10.1017/s0265021508004857 · Cited by 14
Park, M. H., & Hiller, E. A. (2011) · PubMed · Cited by 8
Using Evidence to Enhance the Recovery of Patients Undergoing Colorectal Surgery: Part 1
Maxson, P. M., Lovely, J. K., Wrobleski, D. M., & Isaacson, E. C. (2011) · The Journal of Continuing Education in Nursing · doi:10.3928/00220124-20110324-04 · Cited by 2
Using Evidence to Enhance the Recovery of Patients Undergoing Colorectal Surgery: Part 2
Maxson, P. M., Lovely, J. K., Wrobleski, D. M., & Isaacson, E. C. (2011) · The Journal of Continuing Education in Nursing · doi:10.3928/00220124-20110421-03 · Cited by 2
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Yang, M. M. H., Hartley, R. L., Leung, A. A., Ronksley, P. E., Jetté, N., Casha, S., & Riva-Cambrin, J. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-025091 · Cited by 414
“68 This may be due to greater preoperative severity of pain, opioid-induced hyperalgesia and central or peripheral sensitisation to pre-existing nociception.(23) 69 Further research on the impact of modifying these risk factors in the preoperative Figure 2 Assessment of study quality.”
BackgroundMethodInfluentialEnhanced recovery after surgery for primary hip and knee arthroplasty: a review of the evidence.
Soffin, E., & Yadeau, J. (2016) · British Journal of Anaesthesia · doi:10.1093/bja/aew362 · Cited by 331
Johnson, R. L., Kopp, S. L., Burkle, C. M., Duncan, C. M., Jacob, A. K., Erwin, P. J., Murad, M. H., & Mantilla, C. B. (2016) · British Journal of Anaesthesia · doi:10.1093/bja/aev455 · Cited by 265
Anterior knee pain after total knee arthroplasty: a narrative review
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“If factors are analysed which may be responsible for anterior knee pain after TKA, it is important to know the natural course of pain after uncomplicated TKA [37].”
BackgroundBrummett, C. M., Janda, A. M., Schueller, C. M., Tsodikov, A. D., Morris, M., Williams, D. A., & Clauw, D. J. (2013) · Anesthesiology · doi:10.1097/aln.0b013e3182a8eb1f · Cited by 210
Metadata
- Authors
- Liu, S. S., Buvanendran, A., Rathmell, J. P., Sawhney, M., Bae, J. J., Moric, M., Perros, S., Pope, A. J., Poultsides, L., Valle, C. J. D., Shin, N. S., McCartney, C. J. L., Ma, Y., Shah, M., Wood, M. J., Manion, S. C., & Sculco, T. P.
- Affiliations
- Hospital for Special Surgery (US)
- Rush University Medical Center (US)
- Harvard University (US)
- Sunnybrook Health Science Centre (CA)
- Cornell University (US)
- Corresponding author
- Liu, Spencer S.
- ORCID
- Venue
- International Orthopaedics
- Published
- 2012-07-29
- Volume
- 36
- Issue
- 11
- Pages
- 2261-2267
- ISSN
- 0341-2695 (ISSN-L)
- 1432-5195
- PMC
- PMC3479283
- OpenAlex
- W1979180225
- Cited by
- 167
- References
- 24
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 13 · 2023: 10 · 2022: 11 · 2021: 17 · 2020: 13 · 2019: 14 · 2018: 9 · 2017: 18 · 2016: 20 · 2015: 8 · 2014: 15 · 2013: 6 · 2012: 1
- FWCI
- 9.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Orthopaedics (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hospital for Special Surgery
- National Institutes of Health (RR024996)
- National Center for Research Resources (UL1RR024996)
- Topics
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Health Sciences › Medicine › Surgery › Total Knee Arthroplasty Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- postoperative pain, total hip arthroplasty, total knee arthroplasty, preoperative risk factors, general anesthesia, opioid use, antiepileptic drugs, body mass index, preoperative pain, patient stratification, analgesia
- MeSH terms
- Activities of Daily Living, Aged, Cross-Sectional Studies, Female, Hip Joint, Humans, Knee Joint, Male, Middle Aged, Pain Measurement, Pain, Postoperative, Postoperative Pain, Predictive Value of Tests, Prognosis, Retrospective Studies, Risk Factors, Sex Factors, Triage, Treatment Outcome, Practice Guidelines as Topic, Patient Selection, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Pain Management
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