Catechol-modified hyaluronic acid: In situ-forming hydrogels by auto-oxidation of catechol or photo-oxidation using visible light
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Sato and coworkers showed that in a weakly alkaline environment (pH 7.4), HA-CA with a high molar mass and catechol content was capable of self-assembly into a crosslinked network within about three hours without the addition of additional enzymes or oxidizing agents; this gelation process was mainly due to the oxidation-induced coupling of the catechol groups.
“They showed that in a weakly alkaline environment (pH 7.4), HA-CA, with a high molar mass and catechol content, was capable of self-assembly into a crosslinked network within about three hours without the addition of additional enzymes or oxidizing agents. This gelation process was mainly due to the oxidation-induced coupling of the catechol groups [66].”
From Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications (2024) · cites this paper as [66]
Cites
Cross-Linking in Adhesive Quinoproteins: Studies with Model Decapeptides
Burzio, L. A., & Waite, J. H. (2000) · Biochemistry · doi:10.1021/bi0002434 · Cited by 485 · see citing works
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Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications
Dou, W., Zeng, X., Zhu, S., Zhu, Y., Liu, H., & Li, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25169100 · Cited by 52 · see citing works
“This gelation process was mainly due to the oxidation-induced coupling of the catechol groups [66].”
Background
- Authors
- Sato, T., Aoyagi, T., Ebara, M., & Auzély-Velty, R.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Nihon University (JP)
- University of Tsukuba (JP)
- Venue
- Polymer Bulletin
- Published
- 2017-02-17
- Volume
- 74
- Issue
- 10
- Pages
- 4069-4085
- ISSN
- 0170-0839 (ISSN-L)
- 1436-2449
- OpenAlex
- W2588238013
- Cited by
- 30
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 3
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymer Bulletin (publishedVersion)
- Funders
- JSPS Fellows KAKENHI (265612)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Keywords
- in situ forming hydrogels, self-crosslinking, autoxidation, photooxidation, visible light, injectable hydrogel, gelation kinetics, degree of substitution, wound closure, drug delivery
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