Intratumoral and peritumoral radiomics for preoperative prediction of neoadjuvant chemotherapy effect in breast cancer based on contrast-enhanced spectral mammography
Abstract
Objective To investigative the performance of intratumoral and peritumoral radiomics based on contrast-enhanced spectral mammography (CESM) to preoperatively predict the effect of the neoadjuvant chemotherapy (NAC) of breast cancers.Materials and methods A total of 118 patients with breast cancer who underwent preoperative CESM and NAC from July 2017 to June 2020 were retrospectively analyzed, and the patients were grouped into training (n = 81) and test sets (n = 37) according to the CESM examination time. NAC effect for each patient was assessed by pathology. Intratumoral and peritumoral radiomics features were extracted from CESM images, and feature selection was performed through the Mann-Whitney U test and least absolute shrinkage and selection operator regression (LASSO). Five radiomics signatures based on intratumoral regions, 5-mm peritumoral regions, 10-mm peritumoral regions, intratumoral regions + 5-mm peritumoral regions, and intratumoral regions + 10-mm peritumoral regions were calculated through a linear combination of selected features weighted by their respective coefficients. The prediction performance of radiomics signatures was assessed by the area under the receiver operator characteristic (ROC) curve, the precision-recall (P-R) curve, the calibration curve, and decision curve analysis (DCA).Results Ten radiomics features were selected to establish the radiomics signature of intratumoral regions + 5-mm peritumoral regions, which yielded a maximum AUC of 0.85 (95% CI, 0.72-0.98) in the test set. The calibration curves, P-R curves, and DCA showed favorable predictive performance of the five radiomics signatures.Conclusion The intratumoral and peritumoral radiomics based on CESM exhibited potential for predicting the NAC effect in breast cancer, which could guide treatment decisions.Key points • The intratumoral and peritumoral CESM-based radiomics signatures show good performance in predicting the NAC effect in breast cancer.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Radiomics shows promising outcomes in predicting NAC response in patients with breast cancer using medical images.
“We previously reported that radiomics shows promising outcomes in predicting NAC response in patients with breast cancer by using medical images (10).”
From A multimodal and fully automated system for prediction of pathological complete response to neoadjuvant chemotherapy in breast cancer (2025) · cites this paper as [10]
Cites
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21660 · Cited by 108,699 · see citing works
A guideline of selecting and reporting intraclass correlation coefficients for reliability research
Koo, T. K., & Li, M. Y. (2016) · Journal of Chiropractic Medicine · doi:10.1016/j.jcm.2016.02.012 · Cited by 29,639 · see citing works
Decision curve analysis: a novel method for evaluating prediction models
Vickers, A. J., & Elkin, E. B. (2006) · Medical Decision Making · doi:10.1177/0272989x06295361 · Cited by 6,341 · see citing works
Radiomics: extracting more information from medical images using advanced feature analysis
Lambin, P., Rios-Velazquez, E., Leijenaar, R., Carvalho, S., van Stiphout, R. G. P. M., Granton, P., Zegers, C. M. L., Gillies, R., Boellard, R., Dekker, A., et al. (2012) · European Journal of Cancer · doi:10.1016/j.ejca.2011.11.036 · Cited by 6,084 · see citing works
Saito, T., & Rehmsmeier, M. (2015) · PLOS ONE · doi:10.1371/journal.pone.0118432 · Cited by 5,309 · see citing works
Harbeck, N., & Gnant, M. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31891-8 · Cited by 2,316 · see citing works
Brierley, J. D., Gospodarowicz, M. K., & Wittekind, C. (2017) · TNM Online · doi:10.1002/9780471420194.tnmc26.pub3 · Cited by 1,231 · see citing works
Braman, N. M., Etesami, M., Prasanna, P., Dubchuk, C., Gilmore, H. L., Tiwari, P., Plecha, D. M., & Madabhushi, A. (2017) · Breast Cancer Research · doi:10.1186/s13058-017-0846-1 · Cited by 634 · see citing works
Liu, Z., Li, Z., Qu, J., Zhang, R., Zhou, X., Li, L., Sun, K., Tang, Z., Jiang, H., Li, H., et al. (2019) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-3190 · Cited by 494 · see citing works
Jochelson, M. S., Dershaw, D. D., Sung, J. S., Heerdt, A. S., Thornton, C. M., Moskowitz, C. S., Ferrara, J., & Morris, E. A. (2012) · Radiology · doi:10.1148/radiol.12121084 · Cited by 424 · see citing works
TNM classification of malignant tumours
Brierley, J., Gospodarowicz, M. K., Wittekind, C., & Câncer, U. I. C. L. (2017) · Cited by 360 · see citing works
Braman, N. M., Prasanna, P., Whitney, J. R., Singh, S., Beig, N. G., Etesami, M., Bates, . D. B., Gallagher, K. M., Bloch, B., Vulchi, M., et al. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.2561 · Cited by 327 · see citing works
Lobbes, M. B. I., Lalji, U. C., Houwers, J. B., Nijssen, E. C., Nelemans, P. J., van Roozendaal, L. M., Smidt, M. L., Heuts, E. M., & Wildberger, J. E. (2014) · European Radiology · doi:10.1007/s00330-014-3154-5 · Cited by 211 · see citing works
Cheung, Y., Lin, Y., Wan, Y., Yeow, K., Huang, P.-C., Lo, Y., Tsai, H.-P., Ueng, S., & Chang, C. (2014) · European Radiology · doi:10.1007/s00330-014-3271-1 · Cited by 198 · see citing works
Goetz, M. P., Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C. T., ELIAS, A. D., et al. (2019) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2019.0009 · Cited by 195 · see citing works
Lee‐Felker, S., Tekchandani, L., Thomas, M., Gupta, E., Andrews-Tang, D., Roth, A. R., Sayre, J. W., & Rahbar, G. (2017) · Radiology · doi:10.1148/radiol.2017161592 · Cited by 155 · see citing works
Approaches to Regularized Regression – A Comparison between Gradient Boosting and the Lasso
Schmid, M. C., Gefeller, O., Waldmann, E., Mayr, A. J., & Hepp, T. (2016) · Methods of Information in Medicine · doi:10.3414/me16-01-0033 · Cited by 132 · see citing works
Mammography: an update of the EUSOBI recommendations on information for women
for the European Society of Breast Imaging (EUSOBI), W. L. R. B. E. D. E. B. C. C., Sardanelli, F., Fallenberg, E. M., Clauser, P., Trimboli, R. M., Herrero, J. C., Helbich, T. H., & Forrai, G. (2016) · Insights into Imaging · doi:10.1007/s13244-016-0531-4 · Cited by 127 · see citing works
Phillips, J., Miller, M. M., Mehta, T. S., Fein-Zachary, V. J., Nathanson, A., Hori, W., Monahan-Earley, R. A., & Slanetz, P. J. (2016) · Clinical Imaging · doi:10.1016/j.clinimag.2016.12.011 · Cited by 118 · see citing works
Łuczyńska, E., Heinze, S., Dyczek, S., Blecharz, P., Ryś, J., & Reinfuss, M. (2014) · Korean Journal of Radiology · doi:10.3348/kjr.2014.15.6.689 · Cited by 110 · see citing works
Romeo, V., Cuocolo, R., Apolito, R., Stanzione, A., Ventimiglia, A., Vitale, A., Verde, F., Accurso, A., Amitrano, M., Insabato, L., et al. (2021) · European Radiology · doi:10.1007/s00330-021-08009-2 · Cited by 103 · see citing works
Contrast-enhanced spectral mammography (CESM)
James, J. J., & Tennant, S. L. (2018) · Clinical Radiology · doi:10.1016/j.crad.2018.05.005 · Cited by 102 · see citing works
Qu, Y., Zhu, H., Cao, K., Li, X., Ye, M., & Sun, Y. (2020) · Thoracic Cancer · doi:10.1111/1759-7714.13309 · Cited by 96 · see citing works
Forgia, D. L., Fanizzi, A., Campobasso, F., Bellotti, R., Didonna, V., Lorusso, V., Moschetta, M., Massafra, R., Tamborra, P., Tangaro, S., et al. (2020) · Diagnostics · doi:10.3390/diagnostics10090708 · Cited by 92 · see citing works
Added Value of Radiomics on Mammography for Breast Cancer Diagnosis: A Feasibility Study
Mao, N., Yin, P., Wang, Q., Liu, M., Dong, J., Zhang, X., Xie, H., & Hong, N. (2018) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2018.09.041 · Cited by 90 · see citing works
Self-citationKatayama, A., Miligy, I. M., Shiino, S., Toss, M. S., Eldib, K., Kurozumi, S., Quinn, C., Badr, N. M., Murray, C. A., Provenzano, E., et al. (2021) · Modern Pathology · doi:10.1038/s41379-021-00738-5 · Cited by 88 · see citing works
Adoui, M. E., Drisis, S., & Benjelloun, M. (2020) · International Journal of Computer Assisted Radiology and Surgery · doi:10.1007/s11548-020-02209-9 · Cited by 82 · see citing works
Gullo, R. L., Eskreis‐Winkler, S., Morris, E. A., & Pinker, K. (2019) · The Breast · doi:10.1016/j.breast.2019.11.009 · Cited by 79 · see citing works
Suter, M. B., Pesapane, F., Agazzi, G. M., Gagliardi, T., Nigro, O., Bozzini, A. C., Priolo, F., Penco, S., Cassano, E., Chini, C., et al. (2020) · The Breast · doi:10.1016/j.breast.2020.06.005 · Cited by 76 · see citing works
Zhou, Q. M., Zhe, L., Brooke, R. J., Hudson, M. M., & Yuan, Y. (2021) · Diagnostic and Prognostic Research · doi:10.1186/s41512-021-00102-w · Cited by 64 · see citing works
Mao, N., Yin, P., Li, Q., Wang, Q., Liu, M., Ma, H., Dong, J., Che, K., Wang, Z., Duan, S., et al. (2019) · European Radiology · doi:10.1007/s00330-020-07016-z · Cited by 59 · see citing works
Self-citationZhang, X., Yang, Z., Cui, W., Zheng, C., Li, H., Li, Y., Lu, L., Mao, J., Zeng, W., Yang, X., et al. (2021) · European Radiology · doi:10.1007/s00330-020-07674-z · Cited by 55 · see citing works
Tang, S., Xiang, C., & Yang, Q. (2020) · British Journal of Radiology · doi:10.1259/bjr.20200301 · Cited by 52 · see citing works
Losurdo, L., Fanizzi, A., Basile, T. M. A., Bellotti, R., Bottigli, U., Dentamaro, R., Didonna, V., Lorusso, V., Massafra, R., Tamborra, P., et al. (2019) · Entropy · doi:10.3390/e21111110 · Cited by 50 · see citing works
Comes, M. C., Forgia, D. L., Didonna, V., Fanizzi, A., Giotta, F., Latorre, A. C., Martinelli, E., Mencattini, A., Paradiso, A., Tamborra, P., et al. (2021) · Cancers · doi:10.3390/cancers13102298 · Cited by 50 · see citing works
Bian, T., Wu, Z., Lin, Q., Wang, H., Ge, Y., Duan, S., Fu, G., Cui, C., & Su, X. (2020) · British Journal of Radiology · doi:10.1259/bjr.20200287 · Cited by 49 · see citing works
Radiomics Nomogram of DCE-MRI for the Prediction of Axillary Lymph Node Metastasis in Breast Cancer
Mao, N., Dai, Y., Lin, F., Ma, H., Duan, S., Xie, H., Zhao, W., & Hong, N. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.541849 · Cited by 42 · see citing works
Self-citationLin, F., Wang, Z., Zhang, K., Yang, P., Ma, H., Shi, Y., Liu, M., Wang, Q., Cui, J., Mao, N., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.573630 · Cited by 39 · see citing works
Self-citationWang, Z., Lin, F., Ma, H., Shi, Y., Dong, J., Yang, P., Zhang, K., Guo, N., Zhang, R., Cui, J., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.605230 · Cited by 39 · see citing works
Self-citationChen, S., Liu, Y., Ouyang, Q.-W., Huang, L., Luo, R.-C., & Shao, Z. (2014) · Annals of Surgical Oncology · doi:10.1245/s10434-014-3894-0 · Cited by 29 · see citing works
Pötsch, N., Dietzel, M., Kapetas, P., Clauser, P., Pinker, K., Ellmann, S., Uder, M., Helbich, T. H., & Baltzer, P. (2021) · European Radiology · doi:10.1007/s00330-021-07787-z · Cited by 26 · see citing works
Mao, N., Wang, Q., Liu, M., Dong, J., Xiao, C., Sun, N., Zhang, X., Xie, H., Yin, P., & Hong, N. (2018) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0000000000000793 · Cited by 14 · see citing works
Self-citationCortina, C. S., Gottschalk, N., Kulkarni, S., & Karst, I. (2020) · Journal of Surgical Research · doi:10.1016/j.jss.2020.07.025 · Cited by 8 · see citing works
Murphy, L. C., Quinn, E. M., Razzaq, Z., Brady, C., Livingstone, V., Duddy, L., Barry, J. E., Redmond, H. P., & Corrigan, M. A. (2020) · The Breast Journal · doi:10.1111/tbj.14065 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 45 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Radiomics in breast cancer: Current advances and future directions
Qi, Y.-J., Su, G.-H., You, C., Zhang, X., Xiao, Y., Jiang, Y.-Z., & Shao, Z. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101719 · Cited by 195 · see citing works
Zhang, J., Wu, Q., Yin, W., Yang, L., Xiao, B., Wang, J., & Yao, X. (2023) · BMC Cancer · doi:10.1186/s12885-023-10817-2 · Cited by 60 · see citing works
Li, Y., Fan, Y., Xu, D., Li, Y., Zhong, Z., Pan, H., Huang, B., Xie, X., Yang, Y., & Liu, B. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2022.1041142 · Cited by 48 · see citing works
Mao, N., Dai, Y., Zhou, H., Lin, F., Zheng, T., Li, Z., Yang, P., Zhao, F., Li, Q., Wang, W., et al. (2025) · Science Advances · doi:10.1126/sciadv.adr1576 · Cited by 51 · see citing works
“Moreover, 10 to 50 % of patients with breast cancer reach pathological complete response (pCR), which is associated with favorable outcomes ( 4 ).”
Self-citationZhang, S., Shao, H., Li, W., Zhang, H., Lin, F., Zhang, Q., Zhang, H., Wang, Z., Gao, J., Zhang, R., et al. (2023) · European Radiology · doi:10.1007/s00330-023-09513-3 · Cited by 31 · see citing works
Self-citationXie, N., Fan, X., Chen, D., Chen, J., Yu, H., He, M., Liu, H., Yin, X., Li, B., & Wang, H. (2023) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.28538 · Cited by 29 · see citing works
Liu, W., Li, L., Deng, J., & Li, W. (2024) · Computerized Medical Imaging and Graphics · doi:10.1016/j.compmedimag.2024.102415 · Cited by 25 · see citing works
Zhong, L., Shi, L., Zhou, L., Liu, X., Gu, L., & Bai, W. (2023) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims-23-283 · Cited by 25 · see citing works
Zhang, H.-W., Wang, Y., Hu, B., Song, B., Wen, Z.-J., Su, L., Chen, X.-M., Wang, X., Zhou, P., Zhong, X.-M., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-80210-x · Cited by 24 · see citing works
Self-citationChen, K., Wang, J., Li, S., Zhou, W., & Xu, W.-G. (2023) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-023-06150-2 · Cited by 23 · see citing works
Wang, Z., Zhang, H., Lin, F., Zhang, R., Ma, H., Shi, Y., Yang, P., Zhang, K., Zhao, F., Mao, N., et al. (2023) · Academic Radiology · doi:10.1016/j.acra.2023.02.005 · Cited by 24 · see citing works
Self-citationWang, S., Cao, C., Du, T., Wang, J., Li, J., Li, W., & Chen, M. (2024) · Journal of Ultrasound in Medicine · doi:10.1002/jum.16483 · Cited by 23 · see citing works
Cai, L., Sidey-Gibbons, C. J., Nees, J., Riedel, F., Schäfgen, B., Togawa, R., Killinger, K., Heil, J., Pfob, A., & Golatta, M. (2023) · European Radiology · doi:10.1007/s00330-023-10238-6 · Cited by 22 · see citing works
Zhu, S., Wang, S., Guo, S., Wu, R., Zhang, J., Kong, M., Pan, L., Gu, Y., & Yu, S. (2023) · Academic Radiology · doi:10.1016/j.acra.2023.12.005 · Cited by 21 · see citing works
Zhou, J., Bai, Y., Zhang, Y., Wang, Z., Sun, S., Lin, L., Gu, Y., & You, C. (2024) · Cancer Imaging · doi:10.1186/s40644-024-00746-z · Cited by 21 · see citing works
Self-citationLin, Y., Yu, Y., Wang, Q., Huang, K., Guo, S., Zhang, J., He, Y., Yu, X., Zhang, J., Meng, F., et al. (2025) · npj Precision Oncology · doi:10.1038/s41698-025-01012-6 · Cited by 20 · see citing works
Yao, J., Jia, X., Zhou, W., Zhu, Y., Chen, X., Zhan, W. W., & Zhou, J. (2024) · iScience · doi:10.1016/j.isci.2024.110716 · Cited by 18 · see citing works
Xiong, L., Tang, X., Jiang, X., Chen, H., Qian, B., Chen, B., Lin, X., Zhou, J., & Li, L. (2024) · Breast Cancer Research · doi:10.1186/s13058-024-01909-3 · Cited by 17 · see citing works
ELSayed, B. B., Alksas, A., Shehata, M., Mahmoud, A. H., Zaky, M. M., Alghandour, R., Abdelwahab, K. M., Abdelkhalek, M., Ghazal, M. A., Contractor, S. G., et al. (2023) · Cancers · doi:10.3390/cancers15215288 · Cited by 16 · see citing works
Chen, X., Zhuang, Z., Pen, L., Xue, J., Zhu, H., Zhang, L., & Wang, D. (2024) · Abdominal Radiology · doi:10.1007/s00261-023-04165-9 · Cited by 16 · see citing works
Fan, X., Yu, H., Xie, N., Chen, G., Li, T., Chen, J., He, M., Liu, H., Wang, H., & Yin, X. (2023) · British Journal of Radiology · doi:10.1259/bjr.20221086 · Cited by 15 · see citing works
Wang, J., Gao, W., Lu, M., Yao, X., & Yang, D. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1290313 · Cited by 15 · see citing works
Xu, M., Yang, H.-M., Sun, J., Hao, H., Li, X., & Liu, G. (2023) · Academic Radiology · doi:10.1016/j.acra.2023.11.010 · Cited by 15 · see citing works
Gan, Y., Hu, Q., Shen, Q., Peng, L., Qian, Q., Zhuo, M., Xue, E., & Chen, Z. (2024) · Annals of Surgical Oncology · doi:10.1245/s10434-024-16697-5 · Cited by 14 · see citing works
Sevgili, S. A., & Şenol, S. (2022) · Pediatric Research · doi:10.1038/s41390-022-02356-6 · Cited by 16 · see citing works
Deng, T., Liang, J., Yan, C., Ni, M., Xiang, H., Li, C., Ou, J., Lin, Q., Liu, L., Tang, G., et al. (2024) · Cancer Imaging · doi:10.1186/s40644-024-00676-w · Cited by 11 · see citing works
Hou, X., Chen, K., Wan, X., Luo, H., Li, X., & Xu, W. (2024) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-024-05987-w · Cited by 11 · see citing works
Shang, F., Tan, Z., Gong, T., Tang, X., Sun, H., & Liu, S. (2023) · NMR in Biomedicine · doi:10.1002/nbm.4945 · Cited by 10 · see citing works
Li, G., Huang, X., Wu, H., Tian, H., Huang, Z., Wang, M., Liu, Q., Xu, J., Cui, L., & Dong, F. (2024) · Clinical Breast Cancer · doi:10.1016/j.clbc.2024.11.011 · Cited by 10 · see citing works
Zhu, Z., Wu, K., Lu, J., Dai, S., Xu, D., Fang, W., Yu, Y., & Gu, W. (2025) · BMC Medical Imaging · doi:10.1186/s12880-025-01646-9 · Cited by 10 · see citing works
Wang, J., Tian, C., Zheng, B., Zhang, J., Jiao, D., Qu, J., & Liu, Z. (2024) · BMC Cancer · doi:10.1186/s12885-024-12257-y · Cited by 9 · see citing works
Zhang, M.-Q., Du, Y. L., Zha, H., Liu, X., Cai, M.-J., Chen, Z., Chen, R., Wang, J., Wang, S.-J., Zhang, J., et al. (2022) · British Journal of Radiology · doi:10.1259/bjr.20220626 · Cited by 9 · see citing works
Jiang, W., Deng, X., Zhu, T., Fang, J., & Li, J. (2023) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s418376 · Cited by 8 · see citing works
Zhu, Y., Zhang, S., Wei, W., Li, Y., Wang, L., Wang, Y., Fan, Y., Sun, H., & Xie, Z. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1561599 · Cited by 8 · see citing works
Zhang, K., Lin, J., Lin, F., Wang, Z., Zhang, H., Zhang, S., Mao, N., & Qiao, G. (2023) · Journal of X-Ray Science and Technology · doi:10.3233/xst-221349 · Cited by 8 · see citing works
Self-citationGao, Y., Ding, D., & Zeng, H. (2024) · Engineering Applications of Artificial Intelligence · doi:10.1016/j.engappai.2024.109431 · Cited by 9 · see citing works
Cao, M., Liu, X., Yang, A., Xu, Y. H., Zhang, Q., & Cao, Y. (2025) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2025.110434 · Cited by 7 · see citing works
Jiang, Z., Li, Q., Ruan, J., Li, Y., Zhang, D., Xu, Y., Liao, Y., Zhang, X., Gao, D., & Li, Z. (2024) · Clinical Lung Cancer · doi:10.1016/j.cllc.2024.04.006 · Cited by 7 · see citing works
Jin, Y., Zhao, M., Su, T., Fan, Y., Ouyang, Z., & Lv, F. (2025) · Journal of Medical Internet Research · doi:10.2196/69864 · Cited by 6 · see citing works
Wang, Y., Shang, Y., Guo, Y., Hai, M., Gao, Y., Wu, Q., Li, S., Liao, J., Sun, X., Wu, Y., et al. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1357145 · Cited by 6 · see citing works
Wang, X., Deng, C. L., Kong, R., Gong, Z., Dai, H., Song, Y., Wu, Y., Bi, G., Ai, C., & Bi, Q. (2024) · Academic Radiology · doi:10.1016/j.acra.2024.09.039 · Cited by 5 · see citing works
Xu, R., Wang, K., Peng, B., Zhou, X., Wang, C., Lu, T., Shi, J., Zhao, J., & Zhang, L. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1427743 · Cited by 5 · see citing works
Zhang, X., Qiu, X., Zhang, Y., Lai, Q., Zhang, G., & Zhang, G. (2025) · Cancer Imaging · doi:10.1186/s40644-025-00824-w · Cited by 5 · see citing works
Mo, S., Nan, Y., Qin, F., Zhao, H., Wang, Y., Qin, H., Wei, H., Jiang, H., & Qin, S. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1442209 · Cited by 5 · see citing works
Contrast-enhanced mammography: better with AI?
Zhang, T., & Mann, R. M. (2023) · European Radiology · doi:10.1007/s00330-023-10190-5 · Cited by 5 · see citing works
Yao, J., Zhou, W. Z., Jia, X., Zhu, Y., Chen, X., Zhan, W., & Zhou, J. (2025) · Breast Cancer Research and Treatment · doi:10.1007/s10549-025-07727-1 · Cited by 4 · see citing works
Liang, Y., Xu, H., Lin, J., Tang, W., Liu, X., Gan, K., Wan, Q., & Du, X. (2025) · BMC Cancer · doi:10.1186/s12885-025-14407-2 · Cited by 4 · see citing works
Liu, J., Leng, X., Yuan, Z., Li, Y., Luo, H., Chen, J., Li, R., Li, X., He, Z., Zou, Q., et al. (2025) · BMC Cancer · doi:10.1186/s12885-025-15148-y · Cited by 4 · see citing works
Zhang, X., Zhang, G., Qiu, X., Yin, J., Tan, W., Yin, X., Yang, H., Wang, K., & Zhang, Y. (2023) · Lecture notes in computer science · doi:10.1007/978-981-99-7108-4_26 · Cited by 4 · see citing works
Zhang, S., Hou, J., Xia, W., Zhao, Z., Xu, M., Li, S., Xu, C., Zhang, T., & Liu, W. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1389177 · Cited by 4 · see citing works
Self-citationZhang, H., Miao, Q., Fu, Y., Pan, R., Jin, Q., Gu, C., & Ni, X. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1556317 · Cited by 4 · see citing works
Self-citationZhang, M., Liu, X., Du, Y. L., Zha, H., Zha, X., Wang, J., Liu, X., Wang, S.-J., Zou, Q., Zhang, J., et al. (2023) · British Journal of Radiology · doi:10.1093/bjr/tqad014 · Cited by 4 · see citing works
Liao, T., Yang, Y., Lin, X. S., Ouyang, R., Deng, Y., & Ma, J. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1479565 · Cited by 4 · see citing works
Li, G., Li, Q., Wu, H., Huang, Z., Tian, H., Yang, K., Chen, J., Xu, J., Yuan, L., & Dong, F. (2025) · Discover Oncology · doi:10.1007/s12672-025-02406-5 · Cited by 4 · see citing works
Yang, W., Wu, W., Wang, L., Zhang, S., Zhao, J.-J., & Qiang, Y. (2023) · Comput. Biol. Medicine · doi:10.1016/j.compbiomed.2023.107371 · Cited by 4 · see citing works
Cheng, Q., Zhang, J., Hu, M., Wang, S., Liu, Y., Li, J., & Wei, W. (2024) · Bioengineering · doi:10.3390/bioengineering11121257 · Cited by 3 · see citing works
Liang, G., Zhang, S., Zheng, Y., Chen, W., Liang, Y., Dong, Y., Li, L., Li, J., Yang, C., Jiang, Z., et al. (2025) · BMC Medical Imaging · doi:10.1186/s12880-025-01607-2 · Cited by 3 · see citing works
Singh, S., & Healy, N. A. (2024) · Insights into Imaging · doi:10.1186/s13244-024-01869-4 · Cited by 3 · see citing works
Shen, Q., Xiang, C., Han, Y., Li, Y., & Huang, K. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1566555 · Cited by 3 · see citing works
Wang, M., Chen, W., Ren, R., Lin, Y., Tang, J., & Wu, M. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1586715 · Cited by 3 · see citing works
Yang, D., & Gong, F. (2023) · Medical Science Monitor · doi:10.12659/msm.941880 · Cited by 3 · see citing works
Xiang, Y., Hu, Y., Chen, C., Zhi, H., Zhang, Z., Lu, M., Chen, X., Luo, Z., Chen, S., Dias‐Neto, E., et al. (2023) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-23-627 · Cited by 3 · see citing works
Guo, Y., Liao, J., Li, S., Shang, Y., Wang, Y., Wu, Q., Wu, Y., Wang, M., Yan, F., & Tan, H. (2024) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s487988 · Cited by 3 · see citing works
Peters, J., van Leeuwen, M. M., Moriakov, N., van Dijck, J. A. A. M., Mann, R. M., Teuwen, J., Lips, E. H., van den Belt‐Dusebout, A. W., Wesseling, J., de Vries, B. B. L. P., et al. (2025) · British Journal of Cancer · doi:10.1038/s41416-025-02995-6 · Cited by 3 · see citing works
Liu, L., He, S., Niu, Z., Yin, R., Guo, Y., Dou, Z., Ma, W., Ye, Z., & Lu, H. S. (2024) · Gland Surgery · doi:10.21037/gs-23-509 · Cited by 2 · see citing works
Li, X., Xing, L., Zhuo, L., Xue, L., Duan, J., Dong, J., Zhang, Y., Wang, X., Kang, B., Yin, X., et al. (2025) · BMC Medical Imaging · doi:10.1186/s12880-025-02062-9 · Cited by 2 · see citing works
Huang, J.-L., Liu, Q., Wang, C., Lang, X., Zeng, Y.-X., & Zhou, D.-Q. (2026) · Insights into Imaging · doi:10.1186/s13244-026-02226-3 · Cited by 2 · see citing works
Mottola, M., Golfieri, R., & Bevilacqua, A. (2024) · Sensors · doi:10.3390/s24041156 · Cited by 2 · see citing works
Fan, W., Sun, W., Xu, M. Z., Pan, J., & Man, F. Y. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1307907 · Cited by 2 · see citing works
Lv, X., Li, Y., Ding, C., Qin, L., Xu, X., Zheng, Z., & Hou, D. (2025) · European Radiology Experimental · doi:10.1186/s41747-025-00581-2 · Cited by 2 · see citing works
Li, J., Ma, D., Chen, X., Wei, J., Xu, J., Zhao, Y., & Gao, Z. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1569729 · Cited by 1 · see citing works
Chen, X., Huang, Y., Cai, M., Tang, S., Wang, Z., Li, S., Shen, F., & Xiang, Z. (2025) · British Journal of Radiology · doi:10.1093/bjr/tqaf100 · Cited by 1 · see citing works
Self-citationLi, C., Liao, H., Jian, L. I. U., & Gao, J. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2025.1699632 · Cited by 1 · see citing works
Suleymanova, M. M., Karmazanovsky, G. G., Kondratyev, E. V., Popov, A. Y., Nechaev, V. A., Ermoshchenkova, M. S., & Kuzmina, E. S. (2025) · Digital Diagnostics · doi:10.17816/dd634972 · Cited by 1 · see citing works
Wang, Y., Ma, Y., Wang, F., Liu, A., Zhao, M., Bian, K., Zhu, Y., Yin, L., & Ye, Z. (2025) · Academic Radiology · doi:10.1016/j.acra.2025.01.016 · Cited by 1 · see citing works
de Mello, J. M. D. R. B., Sarvacinski, F., Schaefer, F. C., Ercolani, D. S., Lobato, N. R., Martins, Y. C., Zwetsch, G., Bittelbrunn, F. P., Ferreira, C. F., & Damin, A. P. S. (2022) · Cureus · doi:10.7759/cureus.29960 · Cited by 1 · see citing works
SALES PREDICTING TELEMEDICINE SERVICES DURING COVID-19 USING MACHINE LEARNING TECHNIQUES
CUNHA, A. L. M. D., ZUCHETTI, M. F., Oliveira, S., CHIBA, V. I. Z., & Gonçalves, M. C. (2023) · Anais ... Encontro Nacional de Engenharia de Produção/Anais do Encontro Nacional de Engenharia de Produção · doi:10.14488/enegep2023_tn_st_399_1956_46011
Cui, W. (2024) · American Journal of Cancer Research · doi:10.62347/ilij7959
Liu, X., Yang, A., Cao, M., Zhang, Q., & Cao, Y. (2025) · Journal of Radiation Research and Applied Sciences · doi:10.1016/j.jrras.2025.101769
Yao, G., Chen, L., Wu, T., Liu, Y., Wan, Y., Xia, Z., Liu, B., & Zheng, M. (2025) · International Journal of Women s Health · doi:10.2147/ijwh.s539131
Contrast-Enhanced Mammography: A Comprehensive Overview of Current Status and Future Directions
Renganathan, R., Palanisamy, S., Kini, D. V., Subramaniam, P., Krishnappa, L., & Chang, J. M. (2025) · Journal of the Korean Society of Radiology · doi:10.3348/jksr.2025.0053
Zheng, Y., Cai, H., Huang, H., Wu, G., Ren, A., Su, J., Bao, J., & Wu, F. (2025) · Discover Oncology · doi:10.1007/s12672-025-04146-y
Guo, Z., Li, Y., Hao, Y., Lv, Y., Shen, Y., Zhang, Y., Zhang, N., Zhao, T., Xu, X., & Guo, D. (2025) · Cancer Imaging · doi:10.1186/s40644-025-00968-9
Deng, T., Liang, J., Yan, C., Ni, M., Xiang, H., Li, C., Ou, J., Lin, Q., Liu, L., Tang, G., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25322821
Zhang, J., Wu, Q., Yin, W., Yang, L., Xiao, B., Wang, J.-Z., & Yao, X. (2023) · Figshare · doi:10.6084/m9.figshare.22814919
Zhou, J., Bai, Y., Zhang, Y., Wang, Z., Sun, S., Lin, L., Gu, Y., & You, C. (2024) · Figshare · doi:10.6084/m9.figshare.26409955
Self-citationLi, X., Huang, L., Sun, Y. Y., Yang, C., Li, W., Song, H., & Yan, M. (2026) · Research Square · doi:10.21203/rs.3.rs-8217137/v1
Yao, Y., Zhan, P., Yuan, M., Chen, Y., Fan, Y., & Gao, J. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1763646
Lei, X., Qian, G., Sun, Z.-G., Tang, Z.-Q., Liu, Y.-C., Du, R., & Li, Y. (2026) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v18.i4.115635
Shen, Q., Liu, Y., Xu, F., Han, Y., Liu, X. Q., & Huang, K. (2026) · Scientific Reports · doi:10.1038/s41598-026-46970-4
Monkam, P., Duan, X., Zhao, B., Zhao, D., Qi, S., & Qian, W. (2026) · Archives of Computational Methods in Engineering · doi:10.1007/s11831-026-10577-9
Zhang, S., Shi, Z., Siyao, D. U., Zhu, T., Li, P., Zhao, R., Zhu, X., Wu, S., Tan, Y., Xu, W., et al. (2026) · Cancer Letters · doi:10.1016/j.canlet.2026.218508
Peters, J., de Vries, B. B. L. P., van Dijck, J. A. A. M., Mann, R. M., Moriakov, N., Teuwen, J., Karssemeijer, N., Lips, E. H., Wesseling, J., van Leeuwen, M. M., et al. (2026) · npj Breast Cancer · doi:10.1038/s41523-026-00946-9
Xu, C., Qiu, J., Zhang, S., Chen, Y., Wang, X., Zhang, H., Wang, Q., Chu, T., Li, Z. J., Lu, P., et al. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1807530
Self-citationGündoğdu, A., Ozdemir, N. B. U., Wetherilt, C. S., Aktaş, M., Gentile, D., Çomçalı, B., & Yilmaz, O. C. (2026) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-026-04116-0
He, M., Zhu, F., Jiang, F., Liu, Y., Guo, Y., Yang, Y., Jiang, H., Xiong, F., Cheng, W., Xu, Z., et al. (2026) · Oncology Research and Treatment · doi:10.1159/000553438
Zhou, P., Yang, L., He, Y., Wang, L., Zhao, R., Gu, M., Zhu, P., Luo, X., Kong, X., & Du, P. (2026) · Academic Radiology · doi:10.1016/j.acra.2026.09.038
Wei, C., Pan, T., Li, T., Zheng, C., Duan, Y., & Nie, F. (2026) · Cancers · doi:10.3390/cancers18203326
- Authors
- Mao, N., Shi, Y., Lian, C., Wang, Z., Zhang, K., Xie, H., Zhang, H., Chen, Q., Cheng, G., Xu, C., & Dai, Y.
- Affiliations
- Qingdao University (CN)
- Peking University Shenzhen Hospital (CN)
- Corresponding author
- Xu, Cong
- Dai, Yi
- ORCID
- Venue
- European Radiology
- Published
- 2022-01-23
- Volume
- 32
- Issue
- 5
- Pages
- 3207-3219
- ISSN
- 0938-7994 (ISSN-L)
- 1432-1084
- OpenAlex
- W4206941699
- Cited by
- 99
- References
- 45
- Citations by year
- 2026: 14 · 2025: 29 · 2024: 29 · 2023: 23 · 2022: 4
- FWCI
- 12.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Radiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (82001775, 61773244)
- Taishan Scholar Foundation of Shandong Province (tsqn202103197)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Digital Radiography and Breast Imaging
- Keywords
- breast cancer, neoadjuvant chemotherapy response, radiomics, contrast-enhanced mammography, intratumoral region, peritumoral region, radiomics signature, preoperative prediction, treatment response prediction
- MeSH terms
- Breast Neoplasms, Female, Humans, Mammography, Retrospective Studies, Neoadjuvant Therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review