Type 2 diabetes among persons with schizophrenia and other psychotic disorders in a general population survey
Abstract
Schizophrenia and other psychotic disorders are associated with increased risk of developing type 2 diabetes. However, previous studies are mainly based on clinical samples where the comorbidity may be stronger. We investigated in a general population survey the prevalence of type 2 diabetes in persons with psychotic disorders and in users of antipsychotic medication. The study was based on a nationally representative two-stage cluster sample of 8,028 persons aged 30 or over from Finland. Diagnostic assessment of psychotic disorders combined SCID-I interview and case note data. Prevalences of type 2 diabetes, adjusting for age and sex, were estimated by calculating predicted marginals. The prevalence estimate of type 2 diabetes was 22.0% among subjects with schizophrenia, 13.4% among subjects with other nonaffective psychosis and 6.1% in subjects without psychotic disorders. Only two subjects (3.4%) with affective psychosis had type 2 diabetes. Users of all types of antipsychotic medication had increased prevalence of type 2 diabetes. Our results suggest that type 2 diabetes is a major health concern among persons with schizophrenia and other nonaffective psychotic disorders and also in users of antipsychotic medication, but persons with affective psychosis in the general population may not have increased prevalence of type 2 diabetes.
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Individuals with severe mental illness, especially schizophrenia and related thought disorders, have markedly higher rates of type 2 diabetes.
“Studies of people with serious mental illness, particularly schizophrenia and other thought disorders, show significantly increased rates of type 2 diabetes (87).”
From Psychosocial care for people with diabetes: a position statement of the American Diabetes Association (2016) · cites this paper as [87]
Studies of individuals with serious mental illness, particularly schizophrenia and other thought disorders, show significantly increased rates of type 2 diabetes.
“Studies of individuals with serious mental illness, particularly schizophrenia and other thought disorders, show significantly increased rates of type 2 diabetes (415).”
From 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:<i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [415]
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Viertiö, S., Tuulio-Henriksson, A., Perälä, J., Saarni, S. I., Koskinen, S., Sihvonen, M., Lönnqvist, J., & Suvisaari, J. (2012) · European Psychiatry · doi:10.1016/j.eurpsy.2010.12.005 · Cited by 58 · see citing works
Self-citation
- Authors
- Suvisaari, J., Perälä, J., Saarni, S. I., Härkänen, T., Pirkola, S., Joukamaa, M., Koskinen, S., Lönnqvist, J., & Reunanen, A.
- Affiliations
- Helsinki University Hospital (FI)
- Tampere University (FI)
- University of Helsinki (FI)
- Corresponding author
- Suvisaari, Jaana
- Venue
- European Archives of Psychiatry and Clinical Neuroscience
- Published
- 2007-11-07
- Volume
- 258
- Issue
- 3
- Pages
- 129-136
- ISSN
- 0003-9373 (ISSN-L)
- 0940-1334
- 1433-8491
- OpenAlex
- W1991479744
- Cited by
- 68
- References
- 1
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 6 · 2015: 5 · 2014: 2 · 2013: 3 · 2012: 3
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Archives of Psychiatry and Clinical Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Keywords
- type 2 diabetes, schizophrenia, psychosis, antipsychotic drugs, diabetes prevalence, affective psychosis, non-affective psychosis, comorbidities, general population
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Type 2, Female, Finland, Health Surveys, Humans, Insulin, Male, Middle Aged, Psychotic Disorders, Schizophrenia, Antipsychotic Agents, Comorbidity, Prevalence, Chi-Square Distribution, Age Distribution, Mood Disorders
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