Autonomic dysfunctions in idiopathic Parkinson's disease
Abstract
Most patients with Parkinson's disease experience autonomic dysfunction at some point in the course of their disease. In contrast to autonomic dysregulation in multisystem atrophy, they are less severe, and they frequently cause troublesome symptoms only in advanced stages of the disease. The quality of life is nevertheless substantially restricted. Cardiovascular, gastrointestinal and urogenital autonomic dysfunction is predominant. Appropriate diagnosis and treatment can greatly benefit the patient. An interdisciplinary approach is desirable in most cases.
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In Parkinson's disease, the blood pressure drop may last several minutes.
“In PD, the blood pressure drop may last several minutes (Jost 2003).”
From The clinical symptoms of Parkinson's disease. (2016) · cites this paper as Jost 2003
All areas of autonomic function may be affected in Parkinson's disease and this has been reported to affect daily life of over 50% of patients.
“All areas of autonomic function may be affected and this has been reported to affect daily life of over 50% of patients (Jost 2003).”
From The clinical symptoms of Parkinson's disease. (2016) · cites this paper as Jost 2003
Autonomic dysfunction in Parkinson's disease is considered because of involvement of both the central and peripheral postganglionic autonomic nervous system.
“The autonomic dysfunction is considered because of involvement of both the central and peripheral postganglionic autonomic nervous system (Jost 2003).”
From The clinical symptoms of Parkinson's disease. (2016) · cites this paper as Jost 2003
Urinary control disturbances in Parkinson's disease include urinary frequency, urgency and incontinence.
“Urinary control disturbances include urinary frequency, urgency and incontinence (Jost 2003).”
From The clinical symptoms of Parkinson's disease. (2016) · cites this paper as Jost 2003
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The clinical symptoms of Parkinson's disease.
Sveinbjornsdottir, S. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13691 · Cited by 1,410 · see citing works
Parkinson's disease: a dual‐hit hypothesis
Hawkes, C. H., Del Tredici, K., & Braak, H. (2007) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2007.00874.x · Cited by 1,021 · see citing works
Parkinson's Disease: The Dual Hit Theory Revisited
Hawkes, C. H., Del Tredici, K., & Braak, H. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04365.x · Cited by 303 · see citing works
Ohtsuka, C., Sasaki, M., Konno, K., Koide, M., Kato, K., Takahashi, J., Takahashi, S., Kudo, K., Yamashita, F., & Terayama, Y. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.02.012 · Cited by 171 · see citing works
- Authors
- Jost, W. H.
- Affiliations
- Deutsche Klinik für Diagnostik (DE)
- Corresponding author
- Jost, Wolfgang H.
- ORCID
- Jost, Wolfgang H.
- Venue
- Journal of Neurology
- Published
- 2003-02
- Volume
- 250
- Issue
- S1
- Pages
- i28-i30
- ISSN
- 0012-1037 (ISSN-L)
- 0340-5354
- 1432-1459
- OpenAlex
- W2034284770
- Cited by
- 90
- References
- 0
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 2 · 2023: 3 · 2022: 6 · 2021: 1 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 6 · 2015: 4 · 2014: 3 · 2013: 3 · 2012: 5
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- Parkinson's disease, autonomic dysfunction, cardiac autonomic dysfunction, quality of life, diagnosis, treatment, multidisciplinary care
- MeSH terms
- Autonomic Nervous System Diseases, Cardiovascular Diseases, Gastrointestinal Diseases, Humans, Parkinson Disease, Female Urogenital Diseases, Male Urogenital Diseases
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