The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.
MicroRNA—implications for cancer
Open accessAbstract
MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression post-transcriptionally. After the discovery of the first miRNA in the roundworm Caenorhabditis elegans, these short regulatory RNAs have been found to be an abundant class of RNAs in plants, animals, and DNA viruses. About 3% of human genes encode for miRNAs, and up to 30% of human protein coding genes may be regulated by miRNAs. MicroRNAs play a key role in diverse biological processes, including development, cell proliferation, differentiation, and apoptosis. Accordingly, altered miRNA expression is likely to contribute to human disease, including cancer. This review will summarize the emerging knowledge of the connections between human miRNA biology and different aspects of carcinogenesis. Various techniques available to investigate miRNAs will also be discussed.
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Self-citationMicroRNA signatures in human cancers
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Cited by
Bernardo, B. C., Weeks, K. L., Pretorius, L., & McMullen, J. R. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.04.005 · Cited by 894
TarPmiR: a new approach for microRNA target site prediction
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Kanagaraj, N., Beiping, H., Dheen, S. T., & Tay, S. S. W. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.04.039 · Cited by 130
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miR‐338‐3p suppresses neuroblastoma proliferation, invasion and migration through targeting PREX2a
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Metadata
- Authors
- Sassen, S., Miska, E. A., & Caldas, C.
- Venue
- Virchows Archiv
- Published
- 2007-11-27
- Volume
- 452
- Issue
- 1
- Pages
- 1-10
- ISSN
- 0945-6317 (ISSN-L)
- 1432-2307
- OpenAlex
- W2037631027
- Cited by
- 441
- References
- 87
- FWCI
- 7.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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