Generalized joint hypermobility and voiding dysfunction in children: is there any relationship?
Abstract
Unlabelled Voiding dysfunction is a common entity in pediatric urology. It is believed to have a multifactorial etiology. The aim of this study was to investigate whether there is an increased prevalence of generalized joint hypermobility (GJH) in children with voiding dysfunction compared to normal children. Moreover, the prevalence of voiding complaints in patients with and without GJH was assessed. A total of 226 children--aged 5 to 14 years--including 113 patients diagnosed with voiding dysfunction and 113 sex/age/body mass index-matched normal children were recruited. GJH was evaluated in both groups using the Beighton score (4 or more= hypermobile). In the patient’s group, GJH was significantly more frequent than in controls: 51/113 (45 %) versus 19/113 (17 %) (P=0.001). In addition, in both groups, GJH was more prominent in girls than boys (P Conclusion Our findings suggest that children with voiding dysfunction have significantly higher prevalence of GJH compared to normal children. Further studies are needed to determine the cause and effect of these two common presentations and will help to develop a multidisciplinary approach in understanding and management of voiding dysfunction in children.
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There is increasing evidence for lower urinary tract dysfunction as part of the clinical presentation of symptomatic hypermobility.
“There is increasing evidence for the presence of lower urinary tract dysfunction, defined using the NDDIK criteria [39], as part of the clinical presentation of symptomatic hypermobility”
From Pediatric joint hypermobility: a diagnostic framework and narrative review (2023) · cites this paper as [48]
Several studies have identified an increased prevalence of urinary incontinence in hypermobile pediatric case-controlled studies.
“Several studies have identified an increased prevalence of urinary incontinence in hypermobile pediatric case-controlled studies [22, 48, 49].”
From Pediatric joint hypermobility: a diagnostic framework and narrative review (2023) · cites this paper as [48]
Cites
Beighton Score: A Valid Measure for Generalized Hypermobility in Children
Smits-Engelsman, B., Klerks, M., & Kirby, A. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.07.021 · Cited by 389 · see citing works
Joint hypermobility and genetic collagen disorders: are they related?
Grahame, R. (1999) · Archives of Disease in Childhood · doi:10.1136/adc.80.2.188 · Cited by 344 · see citing works
Juul-Kristensen, B., Rogind, H., Jensen, D. V., & Remvig, L. (2007) · Rheumatology · doi:10.1093/rheumatology/kem290 · Cited by 299 · see citing works
Engelbert, R. H. H., Bank, R. A., Sakkers, R. J. B., Helders, P. J. M., Beemer, F. A., & Uiterwaal, C. S. P. M. (2003) · PEDIATRICS · doi:10.1542/peds.111.3.e248 · Cited by 109 · see citing works
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Tinkle, B., Castori, M., Berglund, B., Cohen, H., Grahame, R., Kazkaz, H., & Levy, H. (2017) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31538 · Cited by 499 · see citing works
Castori, M., Morlino, S., Pascolini, G., Blundo, C., & Grammatico, P. (2015) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31431 · Cited by 98 · see citing works
Pediatric joint hypermobility: a diagnostic framework and narrative review
Tofts, L. J., Simmonds, J., Schwartz, S. B., Richheimer, R. M., O’Connor, C., Elias, E., Engelbert, R., Cleary, K., Tinkle, B. T., Kline, A. D., et al. (2023) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-023-02717-2 · Cited by 74 · see citing works
“Several studies have identified an increased prevalence of urinary incontinence in hypermobile pediatric case-controlled studies [22, 48, 49].”
Background
- Authors
- Kajbafzadeh, A.-M., Sharifi-Rad, L., Ladi Seyedian, S. S., Mozafarpour, S., & Paydary, K.
- Affiliations
- Children's Medical Center (IR)
- Corresponding author
- Kajbafzadeh, Abdol-Mohammad
- Venue
- European Journal of Pediatrics
- Published
- 2013-08-20
- Volume
- 173
- Issue
- 2
- Pages
- 197-201
- ISSN
- 0340-6199 (ISSN-L)
- 1432-1076
- OpenAlex
- W2089921069
- Cited by
- 22
- References
- 4
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 1 · 2017: 2 · 2015: 1 · 2014: 1
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Urology and Nephrology Studies
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Keywords
- generalized joint hypermobility, voiding dysfunction, pediatric urology, Beighton score, urinary tract infection, constipation, sex differences, prevalence, children
- MeSH terms
- Adolescent, Child, Child, Preschool, Constipation, Enuresis, Female, Health Surveys, Humans, Iran, Joint Instability, Male, Risk Factors, Statistics as Topic, Urinary Incontinence, Urinary Tract Infections, Urination Disorders, Vesico-Ureteral Reflux, Comorbidity
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