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Cited by 22

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Genetic structure of the early Hungarian conquerors inferred from mtDNA haplotypes and Y-chromosome haplogroups in a small cemetery

Neparáczki, Endre, Juhász, Zoltán, Pamjav, Horolma, Fehér, Tibor, Csányi, Bernadett, Zink, Albert, Maixner, Frank, Pálfi, György, Molnár, Erika, Pap, Ildikó, Kustár, Ágnes, Révész, László, Raskó, István, Török, Tibor·2017·Molecular Genetics and Genomics
DOI 10.1007/s00438-016-1267-z
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Abstract

We applied ancient DNA methods to shed light on the origin of ancient Hungarians and their relation to modern populations. Hungarians moved into the Carpathian Basin from the Eurasian Pontic steppes in the year 895 AD as a confederation of seven tribes, but their further origin remains obscure. Here, we present 17 mtDNA haplotypes and four Y-chromosome haplogroups, which portray the genetic composition of an entire small cemetery of the first generation Hungarians. Using novel algorithms to compare these mitochondrial DNA haplogroups with other ancient and modern Eurasian data, we revealed that a significant portion of the Hungarians probably originated from a long ago consolidated gene pool in Central Asia-South Siberia, which still persists in modern Hungarians. Another genetic layer of the early Hungarians was obtained during their westward migrations by admixing with various populations of European origin, and an important component of these was derived from the Caucasus region. Most of the modern populations, which are genetically closest relatives of ancient Hungarians, today speak non-Indo-European languages. Our results contribute to our understanding of the peopling of Europe by providing ancient DNA data from a still genetically poorly studied period of medieval human migrations.

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Research works printed but not linked: 29

  1. Bartram AK, Poon C, Neufeld JD (2009) Nucleic acid contamination of glycogen used in nucleic acid precipitation and assessment of linear polyacryl amide as an alternative co-precipitant. Biotechniques 47:1019–1022 · DOI
  2. Bandelt HJ, Forster P, Röhl A (1999) Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol 16:37–48 · DOI · Paper page
  3. Benoit J-N, Quatrehomme GF, Carle G, Pognonec P (2013) An alternative procedure for extraction of DNA from ancient and weathered bone fragments. Med Sci Law 53:100–106 · DOI
  4. Bíró A, Fehér T, Bárány G, Pamjav H (2015) Testing Central and Inner Asian admixture among contemporary Hungarians. Forensic Sci Int Genet 15:121–126 · DOI
  5. Brandstatter A, Egyed B, Zimmermann B, Duftner N, Padar Z, Parson W (2007) Migration rates and genetic structure of two Hungarian ethnic groups in Transylvania Romania. Ann Hum Genet 71:791–803 · DOI
  6. Brandt G, Szécsényi-Nagy A, Roth C, Alt KW, Haak W (2015) Human paleogenetics of Europe : the known knowns and the known unknowns. J Hum Evol 79:73–92 · DOI
  7. Champlot S, Berthelot C, Pruvost M, Andrew Bennett E, Grange T, Geigl EM (2010) An efficient multistrategy DNA decontamination procedure of PCR reagents for hypersensitive PCR applications. PLoS One. doi: 10.1371/journalpone0013042 · DOI
  8. Damgaard PB, Margaryan A, Schroeder H, Orlando L, Willerslev E, Allentoft ME (2015) Improving access to endogenous DNA in ancient bones and teeth. Sci Rep 5:11184. doi: 10.1038/srep11184 · DOI · Paper page
  9. Haak W, Brandt G, Jong HND, Meyer C, Ganslmeier R, Heyd V, Hawkesworth C, Pike AWG, Meller H, Alt KW (2008) Ancient DNA Strontium isotopes and osteological analyses shed light on social and kinship organization of the Later Stone Age. PNAS 105:18226–18231 · DOI
  10. Haak W, Balanovsky O, Sanchez JJ, Koshel S, Zaporozhchenko V, Adler CJ, der Sarkissian CSI, Brandt G, Schwarz C, Nicklisch N, Dresely V, Fritsch B, Balanovska E, Villems R, Meller H, Alt KW, Cooper A (2010) Ancient DNA from European early Neolithic farmers reveals their near eastern affinities. PLoS Biol. doi: 10.1371/journalpbio1000536 · DOI
  11. Haber M, Mezzavilla M, Xue Y, Tyler-Smith C (2016) Ancient DNA and the rewriting of human history: be sparing with Occam’s razor. Genome Biol 17:1. doi: 10.1186/s13059-015-0866-z · DOI · Paper page
  12. Juhász Z, Fehér T, Bárány G, Zalán A, Németh E, Pádár Z, Pamjav H (2015) New clustering methods for population comparison on paternal lineages. Mol Genet Genomics 290:767–784 · DOI
  13. Juhász Z, Fehér T, Németh E, Pamjav H (2016) mtDNA analysis of 174 Eurasian populations using a new iterative rank correlation method. Mol Genet Genomics 291:493–509 · DOI
  14. Knapp M, Clarke AC, Horsburgh KA, Matisoo-Smith EA (2012) Setting the stage: Building and working in an ancient DNA laboratory. Ann Anat 194:3–6 · DOI
  15. Lahermo P, Laitinen V, Sistonen P, Béres J, Karcagi V, Savontaus ML (2000) mtDNA polymorphism in the Hungarians: comparison to three other Finno-Ugric-speaking populations. Hereditas 132:35–42 · DOI
  16. Molodin VI, Pilipenko AS, Romaschenko AG, Zhuravlev AA, Trapezov RO, Chikisheva TA (2012) Human migrations in the southern region of the West Siberian Plain during the Bronze Age: Archaeological palaeogenetic and anthropological data in: Population Dynamics in Prehistory and Early History: New Approaches Using Stable Isotopes and Genetics pp 93–112 (Eds: Kaiser E, Burger J and Schier W.) doi: 10.1515/978311026630693 · DOI
  17. Myres NM, Rootsi S, Lin A, Järve M, King RJ, Kutuev I, Cabrera VM, Khusnutdinova EK, Pshenichnov A, Yunusbayev B, Balanovsky O, Balanovska E, Rudan P, Baldovic M, Herrera RJ, Chiaroni J, Di Cristofaro J, Villems R, Kivisild T, Underhill P (2011) A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe. Eur J Hum Genet 19:95–101 · DOI · Paper page
  18. Novembre J (2015) Ancient DNA steps into the language debate. Nature 522:164–165 · DOI
  19. Pamjav H, Juhász Z, Zalán A, Németh E, Damdin B (2012) A comparative phylogenetic study of genetics and folk music. Mol Genet Genomics 287:337–349 · DOI
  20. Pamjav H, Juhász Z, Fehér T, Bárány G, Németh E (2013) Classification of the Y-haplogroup distributions of Western Eurasian populations using a self-learning algorithm Forensic Sci Int Genet Suppl Ser 4 doi: 10.1016/jfsigss201310101 · DOI
  21. Reidla M, Kivisild T, Metspalu E, Kaldma K, Tambets K, Tolk H, Parik J, Loogväli E-L, Derenko M, Malyarchuk B (2003) Origin and Diffusion of mtDNA Haplogroup X. Am J Hum Genet 73:1178–1190 · DOI
  22. Rohland N, Hofreiter M (2007) Ancient DNA extraction from bones and teeth. Nat Protoc 2:1756–1762 · DOI
  23. Róna-Tas A (1999) Hungarians and Europe in the early middle ages: an introduction to early hungarian history. CEU Press · DOI
  24. Roostalu U, Kutuev I, Loogvali EL, Metspalu E, Tambets K, Reidla M, Khusnutdinova EK, Usanga E, Kivisild T, Villems R (2007) Origin and expansion of haplogroup H the dominant human mitochondrial DNA lineage in west Eurasia: the Near Eastern and Caucasian perspective. Mol Biol Evol 24:436–448 · DOI
  25. Rootsi S, Magri C, Kivisild T, Benuzzi G, Help H, Bermisheva M, Kutuev I, Barać L, Pericić M, Balanovsky O, Pshenichnov A, Dion D, Grobei M, Zhivotovsky LA, Battaglia V, Achilli A, Al-Zahery N, Parik J, King R, Cinnioğlu C, Khusnutdinova E, Rudan P, Balanovska E, Scheffrahn W, Simonescu M, Brehm A, Goncalves R, Rosa A, Moisan J-P, Chaventre A, Ferak V, Füredi S, Oefner PJ, Shen P, Beckman L, Mikerezi I, Terzić R, Primorac D, Cambon-Thomsen A, Krumina A, Torroni A, Underhill PA, Santachiara-Benerecetti AS, Villems R, Semino O (2004) Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in europe. Am J Hum Genet 75:128–137 · DOI
  26. Szécsényi-Nagy A, Brandt G, Haak W, Keerl V, Möller-Rieker S, Köhler K, Mende BG, Oross K, Marton T, Osztás A, Kiss V, Fecher M, Pálfi G, Molnár E, Sebők K, Czene A, Paluch T, Šlaus M, Novak M, Pećina-Šlaus N, Ősz B, Voicsek V, Somogyi K, Tóth G, Kromer B, Bánffy E, Alt KW (2015) Tracing the genetic origin of Europe’s first farmers reveals insights into their social organization. Philos Trans R Soc B Biol Sci 282:20150339. doi: 10.1098/rspb20150339 · DOI
  27. Tömöry G, Csányi B, Bogácsi-Szabó E, Kalmár T, Czibula Á, Csősz A, Priskin K, Mende B, Langó P, Downes CS, Raskó I (2007) Comparison of maternal lineage and biogeographic analyses of ancient and modern Hungarian populations. Am J Phys Anthropol 134:354–368 · DOI
  28. Vinogradov VB (1983) Altungarische Parallelen zu einigen Gräbern des alanischen Gräberfeldes bei Martan-Ču. Acta Archaeol Hungarica 35:211–220
  29. Wang CC, Wang LX, Shrestha R, Wen S, Zhang M, Tong X, Jin L, Li H (2015) Convergence of Y Chromosome STR haplotypes from different SNP haplogroups compromises accuracy of haplogroup prediction. J Genet Genomics 47:403–407 · DOI

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Metadata

Authors
Neparáczki, E., Juhász, Z., Pamjav, H., Fehér, T., Csányi, B., Zink, A., Maixner, F., Pálfi, G., Molnár, E., Pap, I., Kustár, Á., Révész, L., Raskó, I., & Török, T.
Venue
Molecular Genetics and Genomics
Publisher
Springer Science and Business Media LLC
Published
2016-11-01
Volume
292
Issue
1
Pages
201-214
ISSN
  • 1617-4615
  • 1617-4623
DOI
10.1007/s00438-016-1267-z
Cited by
22
References
2
Language
en
Licence
www.springer.com/tdm (tdm)
Funders
  • Avicenna Foundation (GF/JSZF/814/9/2015)
  • OTKA (NN 78696, K78555)
  • Hungary-Romania Cross-Border Co-operation Programme (HURO/1101/173/2.2.1)
  • Campus Hungary Fellowship (B2/1SZ/18826)

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