Cited by 43Estrogen and related hormone effectsNerve injury and regenerationHypothalamic control of reproductive hormones

Remodeling of uterine innervation.

Latini, C., Frontini, A., Morroni, M., Marzioni, D., Castellucci, M., Smith, P. G.·2008·Cell and Tissue Research

Abstract

This minireview reports current hypotheses concerning the remodeling of sympathetic innervation in rodent and human uterus during the estrous cycle and gestation. Neural modulation in this organ is related to sexual hormone concentrations, and a reduction in nerve density is observed when estrogen levels are high during the estrous cycle. Estrogen receptor alpha is considered to be the major receptor mediating the action of estrogen. In the uterus, the expression of neurotrophins, such as nerve growth factor, which are involved in the survival and growth of nerve fibers, changes in response to steroid levels. Despite much research, further studies are necessary to clarify various aspects of nerve growth control under diverse physiological conditions. These studies could be of importance, since alterations of the biological mechanisms of uterus innervation may play significant roles in various pathologies, such as infertility and spontaneous abortion.

Integrity signals

Registry

Crossref · 10.1007/s00441-008-0657-x

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

1 of the 53 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Latini, C., Frontini, A., Morroni, M., Marzioni, D., Castellucci, M., & Smith, P. G.
Affiliations
  • Marche Polytechnic University (IT)
  • University of Kansas Medical Center (US)
Corresponding author
Castellucci, M.
Venue
Cell and Tissue Research
Published
2008-08-02
Volume
334
Issue
1
Pages
1-6
ISSN
  • 0302-766X (ISSN-L)
  • 1432-0878
OpenAlex
W2061718936
Cited by
43
References
53
Citations by year
2025: 2 · 2024: 3 · 2023: 3 · 2022: 2 · 2020: 1 · 2019: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 5 · 2013: 5 · 2012: 9
FWCI
0.26
Type
journal article
Language
en
Open access
closed
Locations
  • Cell and Tissue Research (publishedVersion)
  • PubMed (publishedVersion)
  • Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
  • Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Keywords
uterine innervation, sympathetic innervation, estrous cycle, pregnancy, estrogen, estrogen receptor alpha, nerve growth factor, neurotrophins, nerve fiber density, infertility, miscarriage
MeSH terms
Animals, Estrogens, Estrus, Female, Humans, Receptors, Estrogen, Uterus, Receptor, Nerve Growth Factor, Receptor, trkA, Nerve Growth Factor, Estrous Cycle, Mice, Neurogenesis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review