Cited by 305biodegradable polymer synthesis and propertiesMicrobial bioremediation and biosurfactantsBiopolymer Synthesis and Applications

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Production of polyhydroxyalkanoates by mixed microbial cultures

Reis, M. A. M., Serafim, L. S., Lemos, P. C., Ramos, A. M., Aguiar, F. R., Van Loosdrecht, M. C. M.·2003·Bioprocess and Biosystems Engineering

DOI 10.1007/s00449-003-0322-4

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Abstract

Polyhydroxyalkanoates (PHAs) are biodegradable bioplastics formed from renewable resources, like sugars, with similar characteristics of polypropylene. These bioplastics are industrially produced by pure cultures using expensive pure substrates. These factors lead to a much higher selling price of PHAs compared to petroleum-based plastics, like polypropylene. The use of mixed cultures and cheap substrates (waste materials) can reduce costs of PHA production by more than 50%. Storage of PHAs by mixed populations occurs under transient conditions mainly caused by discontinuous feeding and variation in the electron donor/acceptor presence. In the last years the mechanisms of storage, metabolism and kinetics of mixed cultures have been studied. The maximum capacity of PHA storage and production rate is dependent on the substrate and on the operating conditions used. In this paper an overview and discussion of various mechanisms and processes for PHA production by mixed cultures is presented.

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Smolders, G. J. F., van der Meij, J., van Loosdrecht, M. C. M., & Heijnen, J. J. (1994) · Biotechnology and Bioengineering · doi:10.1002/bit.260430605 · Cited by 835
A model for light distribution and average solar irradiance inside outdoor tubular photobioreactors for the microalgal mass culture
Acién, F. G., García-Camacho, F., Pérez, J. A. S., Fernández-Sevilla, J. M., & Grima, E. M. (1997) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19970905)55:5 · Cited by 250
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ATR-FTIR sensor development for continuous on-line monitoring of chlorinated aliphatic hydrocarbons in a fixed-bed bioreactor
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Use of flow field-flow fractionation for the rapid quantitation of ribosome and ribosomal subunits inEscherichia coli at different protein production conditions
Nilsson, M. G., Bülow, L., & Wahlund, K. (1997) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19970605)54:5 · Cited by 33
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Authors: Reis, M. A. M., Serafim, L. S., Lemos, P. C., Ramos, A. M., Aguiar, F. R., & Van Loosdrecht, M. C. M.
Affiliations: Rede de Química e Tecnologia (PT)
Corresponding author: Reis, M. A. M.
ORCID: Reis, M. A. M.
Serafim, L. S.
Lemos, P. C.
Ramos, A. M.
Venue: Bioprocess and Biosystems Engineering
Publisher: Springer Science and Business Media LLC
Published: 2003-04-12
Volume: 25
Issue: 6
Pages: 377-385
ISSN: 1615-7591 (ISSN-L)
1615-7605
DOI: 10.1007/s00449-003-0322-4
OpenAlex: W2032420027
Cited by: 301
References: 9
Citations by year: 2026: 6 · 2025: 16 · 2024: 15 · 2023: 12 · 2022: 23 · 2021: 23 · 2020: 16 · 2019: 14 · 2018: 16 · 2017: 14 · 2016: 21 · 2015: 14 · 2014: 16 · 2013: 18 · 2012: 16
FWCI: 2.22
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Bioprocess and Biosystems Engineering (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Biopolymer Synthesis and Applications
Keywords: polyhydroxyalkanoates, mixed culture, biodegradable bioplastics, waste substrates, electron donors and acceptors

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Production of polyhydroxyalkanoates by mixed microbial cultures

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