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Cited by 29Head and Neck Cancer StudiesOral health in cancer treatmentCancer survivorship and care

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Clinical and sociodemographic factors that affect the quality of life of survivors of head and neck cancer

Bonzanini, Laura Izabel Lampert, Soldera, Eloisa Barbieri, Ortigara, Gabriela Barbieri, Schulz, Riéli Elis, Antoniazzi, Raquel Pippi, Ardenghi, Thiago Machado, Ferrazzo, Kívia Linhares·2020·Supportive Care in Cancer
DOI 10.1007/s00520-019-05008-4
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Abstract

Objective The present cross-sectional study evaluated the quality of life of patients treated with 3-D conformal radiotherapy for cancer of the mouth, oropharynx, hypopharynx, or larynx and investigated possible associations with clinical and sociodemographic variables using multivariate analysis.Methods The sample was composed of 90 patients who had completed treatment at least 3 months earlier. Data were collected from April 2016 to May 2017. The patients were clinically evaluated with regard to stimulated salivary flow, trismus, and radiation caries. Sociodemographic data and data related to the disease (stage, location of primary tumor, and radiation dose) were collected from the patient charts. Quality of life was assessed using the Brazilian version of the University of Washington Quality of Life (UW-QOL) questionnaire. Poisson logistic regression was performed to determine the mean ratio and test associations with the clinical and sociodemographic variables.Results The mean total of the UW-QOL was 814.88 (± 224.58). Patient age, staging of cancer, hyposalivation, and trismus were associated with quality of life. Patients with tumors in the advanced stage, those with hyposalivation and those with trismus respectively had 11% (CI 0.80-0.98), 12% (CI 0.79-0.99), and 15% (CI 0.77-0.94) lower UW-QOL scores, indicating poorer quality of life.Conclusion Survivors of head and neck cancer experience a negative impact on quality of life associated with trismus, hyposalivation, advanced stage tumors, and a younger patient age. The present findings underscore the importance of a specific approach focused on these aspects to ensure better quality of life in the long term.

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Crossref · 10.1007/s00520-019-05008-4

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Metadata

Authors
Bonzanini, L. I. L., Soldera, E. B., Ortigara, G. B., Schulz, R. E., Antoniazzi, R. P., Ardenghi, T. M., & Ferrazzo, K. L.
Affiliations
Universidade Federal de Santa Maria (BR)
Corresponding author
Bonzanini, Laura Izabel Lampert
ORCID
Venue
Supportive Care in Cancer
Publisher
Springer Science and Business Media LLC
Published
2019-08-02
Volume
28
Issue
4
Pages
1941-1950
ISSN
  • 0941-4355 (ISSN-L)
  • 1433-7339
DOI
10.1007/s00520-019-05008-4
OpenAlex
W2966259289
Cited by
29
References
39
Citations by year
2026: 4 · 2025: 3 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 4 · 2020: 6
FWCI
3.17
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Supportive Care in Cancer (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
  • Health Sciences › Dentistry › General Dentistry › Oral health in cancer treatment
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
head and neck cancer survivors, quality of life, 3D conformal radiotherapy, hyposalivation, trismus, radiation caries, stimulated salivary flow, tumor stage, patient age, sociodemographic factors, oropharyngeal cancer, laryngeal cancer, hypopharyngeal cancer, oral cancer
MeSH terms
Cancer Survivors, Squamous Cell Carcinoma of Head and Neck, Adult, Aged, Brazil, Cross-Sectional Studies, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Radiation Injuries, Socioeconomic Factors, Trismus, Xerostomia

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