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Cited by 56Telemedicine and Telehealth ImplementationCancer survivorship and careMobile Health and mHealth Applications

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Nurse-led telehealth interventions for symptom management in patients with cancer receiving systemic or radiation therapy: a systematic review and meta-analysis

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Kwok, Chanel, Degen, Charlena, Moradi, Narges, Stacey, Dawn·2022·Supportive Care in Cancer
DOI 10.1007/s00520-022-07052-zPMC PMC9008678
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Abstract

Purpose Patients receiving cancer treatments experience many treatment-related symptoms. Telehealth is increasingly being used to support symptom management. The overall aim was to determine the effectiveness of nurse-led telehealth symptom management interventions for patients with cancer receiving systemic or radiation therapy compared to usual care on health service use, quality of life, and symptom severity. Methods A systematic review was conducted following the Cochrane Handbook and PRISMA reporting guidelines. Five electronic databases were searched. Two independent reviewers screened articles and extracted data. Meta-analysis was performed if data were clinically and methodologically homogeneous. Subanalysis was conducted on reactive and scheduled telehealth interventions. Results Of 7749 citations screened, 10 studies were included (8 randomized control trials, 2 quasi-experimental). Five were reactive telehealth interventions with patient-initiated contact and five evaluated scheduled telehealth interventions initiated by nurses. Compared to usual care (typically patient-initiated calls), nurse-led telehealth interventions for symptom management showed no statistically significant difference in hospitalizations, emergency department visits, or unscheduled clinic visits. Two of three studies of reactive telehealth interventions showed improved quality of life. All telehealth interventions showed reduction in the severity of most symptoms. Pain severity was significantly reduced (standard mean difference - 0.54; 95% CI - 0.88, - 0.19). Significant heterogeneity prevented meta-analysis for most outcomes. Conclusion Few studies evaluated nurse-led telehealth interventions for cancer symptom management. Compared to usual care, patients exposed to telehealth interventions had reduced symptom severity and no difference in health services use. Future research should focus on better reporting intervention characteristics and consistently measuring outcomes.

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  • Systematic reviews have consistently shown that virtual care and remote symptom monitoring can improve access, patient satisfaction, symptom management, and continuity of care, particularly for rural and underserved populations.

    “Systematic reviews have consistently shown that virtual care and remote symptom monitoring can improve access, patient satisfaction, symptom management, and continuity of care, particularly for rural and underserved populations”

    From A Scoping Review of Implemented Innovations in Cancer Care: Implications for Pan-Canadian Scaling (2026) · cites this paper as [32]

    The Discussion reports reduced symptom severity in several telehealth studies and says telehealth can shorten time to access care; the Introduction says patient-reported symptom alerts have been shown to improve satisfaction. The review does not establish improved continuity of care or particular benefits for rural and underserved populations, and its Discussion notes methodological limitations and mixed results rather than consistently demonstrated benefits. Page numbers were not supplied in our copy. (LLM, conf=0.88)

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Metadata

Authors
Kwok, C., Degen, C., Moradi, N., & Stacey, D.
Affiliations
University of Ottawa (CA)
Corresponding author
Stacey, Dawn
ORCID
Venue
Supportive Care in Cancer
Publisher
Springer Science and Business Media LLC
Published
2022-04-14
Volume
30
Issue
9
Pages
7119-7132
ISSN
  • 0941-4355 (ISSN-L)
  • 1433-7339
DOI
10.1007/s00520-022-07052-z
PMC
PMC9008678
OpenAlex
W4223917247
Cited by
56
References
10
Citations by year
2026: 12 · 2025: 20 · 2024: 12 · 2023: 9 · 2022: 3
FWCI
2.19
Type
journal article
Language
en
Open access
Licence
Locations
  • Supportive Care in Cancer (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
University of Ottawa
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords
cancer symptom management, systemic therapy, radiotherapy, health care utilization, quality of life, symptom severity, pain intensity, hospitalization, emergency department visits
MeSH terms
Humans, Neoplasms, Quality of Life, Self Care, Telemedicine, Nurse's Role

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