Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial
Open accessAbstract
Purpose: There is growing interest to enhance symptom monitoring during routine cancer care using patient-reported outcomes, but evidence of impact on clinical outcomes is limited. Methods: We randomly assigned patients receiving routine outpatient chemotherapy for advanced solid tumors at Memorial Sloan Kettering Cancer Center to report 12 common symptoms via tablet computers or to receive usual care consisting of symptom monitoring at the discretion of clinicians. Those with home computers received weekly e-mail prompts to report between visits. Treating physicians received symptom printouts at visits, and nurses received e-mail alerts when participants reported severe or worsening symptoms. The primary outcome was change in health-related quality of life (HRQL) at 6 months compared with baseline, measured by the EuroQol EQ-5D Index. Secondary endpoints included emergency room (ER) visits, hospitalizations, and survival. Results: Among 766 patients allocated, HRQL improved among more participants in the intervention group than usual care (34% v 18%) and worsened among fewer (38% v 53%; P < .001). Overall, mean HRQL declined by less in the intervention group than usual care (1.4- v 7.1-point drop; P < .001). Patients receiving intervention were less frequently admitted to the ER (34% v 41%; P = .02) or hospitalized (45% v 49%; P = .08) and remained on chemotherapy longer (mean, 8.2 v 6.3 months; P = .002). Although 75% of the intervention group was alive at 1 year, 69% with usual care survived the year (P = .05), with differences also seen in quality-adjusted survival (mean of 8.7 v. 8.0 months; P = .004). Benefits were greater for participants lacking prior computer experience. Most patients receiving intervention (63%) reported severe symptoms during the study. Nurses frequently initiated clinical actions in response to e-mail alerts. Conclusion: Clinical benefits were associated with symptom self-reporting during cancer care.
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The alert thresholds were based on prior research.
“generate a real-time alert notification sent to the patient's cancer care team, based on prior research.25”
From Implementation of a remote symptom monitoring pathway in oncology care: analysis of real-world experience across 33 cancer centres in France and Belgium (2024) · cites this paper as [25]
The Methods section (page unavailable) states that STAR sent e-mail alerts to nurses when a symptom worsened by at least two points or reached grade 3. It does not say those alert thresholds were based on prior research; its explicit reference to prior work concerns the projected proportion of computer-inexperienced participants, not the thresholds. (LLM, conf=0.82)
Experimental — accuracy not yet measuredPrior trials of ePRO monitoring have demonstrated improved symptom control, quality of life, and survival when structured symptom reporting is coupled with clinician response.
“which have demonstrated improved symptom control, quality of life, and survival when structured symptom reporting is coupled with clinician response [3,4,7]”
From Implementing UK Oncology Nursing Society–Informed Digital Symptom Triage With Episode-Based Review in Routine NHS Acute Oncology: Service Evaluation (2026) · cites this paper as [3]
ePRO systems have demonstrated that symptom monitoring with clinician response improves symptom control and survival.
“Electronic patient-reported outcome (ePRO) systems have demonstrated that symptom monitoring with clinician response improves symptom control and survival [3,4].”
From Implementing UK Oncology Nursing Society–Informed Digital Symptom Triage With Episode-Based Review in Routine NHS Acute Oncology: Service Evaluation (2026) · cites this paper as [3]
The findings of this evaluation are consistent with prior trials of ePRO monitoring.
“The findings of this evaluation are consistent with prior trials of ePRO monitoring”
From Implementing UK Oncology Nursing Society–Informed Digital Symptom Triage With Episode-Based Review in Routine NHS Acute Oncology: Service Evaluation (2026) · cites this paper as [3]
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Cites
EuroQol: a new facility for the measurement of health-related quality of life
(1990) · Health Policy · doi:10.1016/0168-8510(90)90421-9 · Cited by 15,736 · see citing works
A Class of $K$-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk
Gray, R. J. (1988) · The Annals of Statistics · doi:10.1214/aos/1176350951 · Cited by 4,957 · see citing works
Velikova, G., Booth, L., Smith, A. B., Brown, P. M., Lynch, P., Brown, J. M., & Selby, P. J. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.06.078 · Cited by 1,382 · see citing works
Detmar, S. B., Muller, M. J., Schornagel, J. H., Wever, L. D. V., & Aaronson, N. K. (2002) · JAMA · doi:10.1001/jama.288.23.3027 · Cited by 1,011 · see citing works
Kotronoulas, G., Kearney, N., Maguire, R., Harrow, A., Domenico, D. D., Croy, S., & MacGillivray, S. A. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2013.53.5948 · Cited by 953 · see citing works
Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer
Pickard, A. S., Neary, M. P., & Cella, D. F. (2007) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-5-70 · Cited by 932 · see citing works
Snyder, C. F., Aaronson, N. K., Choucair, A. K., Elliott, T. E., Greenhalgh, J., Halyard, M. Y., Hess, R., Miller, D. M., Reeve, B. B., & Santana, M. (2011) · Quality of Life Research · doi:10.1007/s11136-011-0054-x · Cited by 910 · see citing works
Chen, J., Ou, L., & Hollis, S. J. (2013) · BMC Health Services Research · doi:10.1186/1472-6963-13-211 · Cited by 796 · see citing works
Valderas, J. M., Kotzeva, A., Espallargues, M., Guyatt, G., Ferrans, C. E., Halyard, M. Y., Revicki, D. A., Symonds, T., Parada, A., & Alonso, J. (2008) · Quality of Life Research · doi:10.1007/s11136-007-9295-0 · Cited by 775 · see citing works
Adverse Symptom Event Reporting by Patients vs Clinicians: Relationships With Clinical Outcomes
Basch, E., Jia, X., Heller, G., Leahy, A. B., Sit, L., Fruscione, M., Appawu, M., Iasonos, A. E., Atkinson, T. M., Goldfarb, S. B., et al. (2009) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djp386 · Cited by 622 · see citing works
Self-citationFromme, E. K., Eilers, K. M., Mori, M., Hsieh, Y.-C., & Beer, T. M. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.03.025 · Cited by 555 · see citing works
Basch, E., Abernethy, A. P., Mullins, C. D., Reeve, B. B., Smith, M. L., Coons, S. J., Sloan, J., Wenzel, K., Chauhan, C., Eppard, W., et al. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.42.5967 · Cited by 476 · see citing works
Self-citationHenry, D. H., Viswanathan, H. N., Elkin, E. P., Traina, S., Wade, S. M., & Cella, D. F. (2008) · Supportive Care in Cancer · doi:10.1007/s00520-007-0380-2 · Cited by 384 · see citing works
Laugsand, E. A., Sprangers, M. A. G., Bjordal, K., Skorpen, F., Kaasa, S., & Klepstad, P. (2010) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-8-104 · Cited by 375 · see citing works
Mayer, D. K., Travers, D. A., Wyss, A. B., Leak, A., & Waller, A. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.34.2816 · Cited by 371 · see citing works
Berry, D. L., Blumenstein, B. A., Halpenny, B., Wolpin, S. E., Fann, J. R., Austin-Seymour, M., Bush, N. E., Karras, B. T., Lober, W. B., & McCorkle, R. C. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.30.3909 · Cited by 359 · see citing works
Electronic patient‐reported outcome systems in oncology clinical practice
Bennett, A. V., Jensen, R. E., & Basch, E. (2012) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21150 · Cited by 356 · see citing works
Self-citationCleeland, C. S., Wang, X. S., Shi, Q., Mendoza, T. R., Wright, S. L., Berry, M. D., Malveaux, D., Shah, P. K., Gning, I., Hofstetter, W. L., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.29.8315 · Cited by 341 · see citing works
Patient Online Self-Reporting of Toxicity Symptoms During Chemotherapy
Basch, E., Artz, D. R., Dulko, D., Scher, K. S., Sabbatini, P. J., Hensley, M. L., Mitra, N., Speakman, J., McCabe, M. S., & Schrag, D. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.04.275 · Cited by 308 · see citing works
Self-citationReilly, C. M., Bruner, D. W., Mitchell, S. A., Minasian, L. M., Basch, E., Dueck, A. C., Cella, D. F., & Reeve, B. B. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-012-1688-0 · Cited by 299 · see citing works
Self-citationReview of Electronic Patient-Reported Outcomes Systems Used in Cancer Clinical Care
Jensen, R. E., Snyder, C. F., Abernethy, A. P., Basch, E., Potosky, A. L., Roberts, A. C., Loeffler, D. R., & Reeve, B. B. (2014) · Journal of Oncology Practice · doi:10.1200/jop.2013.001067 · Cited by 296 · see citing works
Self-citationFisch, M. J., Lee, J., Weiss, M., Wagner, L. I., Chang, V. T.-S., Cella, D. F., Manola, J. B., Minasian, L. M., McCaskill‐Stevens, W., Mendoza, T. R., et al. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.39.2381 · Cited by 271 · see citing works
Sullivan, P. W., & Ghushchyan, V. (2006) · Medical Decision Making · doi:10.1177/0272989x06290496 · Cited by 249 · see citing works
Reliability of adverse symptom event reporting by clinicians
Atkinson, T. M., Li, Y., Coffey, C. W., Sit, L., Shaw, M., Lavene, D., Bennett, A. V., Fruscione, M., Rogak, L. J., Hay, J. L., et al. (2011) · Quality of Life Research · doi:10.1007/s11136-011-0031-4 · Cited by 234 · see citing works
Self-citationTelecare Collaborative Management of Chronic Pain in Primary Care: A Randomized Clinical Trial
Kroenke, K., Krebs, E. E., Wu, J., Yu, Z., Chumbler, N. R., & Bair, M. J. (2014) · JAMA · doi:10.1001/jama.2014.7689 · Cited by 206 · see citing works
Basch, E., Iasonos, A. E., Leahy, A. B., Culkin, A., Kris, M. G., Artz, D. R., Fearn, P., Speakman, J., Farquhar, R., Scher, H. I., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.11.2243 · Cited by 201 · see citing works
Self-citationProspects and challenges in using patient-reported outcomes in clinical practice
Fung, C. H., & Hays, R. D. (2008) · Quality of Life Research · doi:10.1007/s11136-008-9379-5 · Cited by 196 · see citing works
Use of information resources by patients with cancer and their companions
Basch, E., Thaler, H. T., Shi, W., Yakren, S., & Schrag, D. (2004) · Cancer · doi:10.1002/cncr.20261 · Cited by 179 · see citing works
Self-citationA consistent estimator for the distribution of quality adjusted survival time
Zhao, H. (1997) · Biometrika · doi:10.1093/biomet/84.2.339 · Cited by 163 · see citing works
Judson, T. J., Bennett, A. V., Rogak, L. J., Sit, L., Leahy, A. B., Kris, M. G., Hudis, C. A., Scher, H. I., Sabbatini, P. J., Schrag, D., et al. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.47.6804 · Cited by 150 · see citing works
Self-citationTrajkovic, M., de Graeff, A., Voest, E. E., & Teunissen, S. C. C. M. (2012) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2012.02.011 · Cited by 126 · see citing works
Seow, H. Y., SUSSMAN, J. S., Martelli-Reid, L., Pond, G. R., & Bainbridge, D. B. (2012) · Journal of Oncology Practice · doi:10.1200/jop.2011.000525 · Cited by 121 · see citing works
Evaluation of an Online Platform for Cancer Patient Self-reporting of Chemotherapy Toxicities
Basch, E., Artz, D. R., Iasonos, A. E., Speakman, J., Shannon, K., Lin, K., Pun, C. D., Yong, H., Fearn, P., Leahy, A. B., et al. (2007) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2177 · Cited by 120 · see citing works
Self-citationGilbert, J. E., Howell, D., King, S., Sawka, C. A., Hughes, E. E., Angus, H. B., & Dudgeon, D. J. (2012) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2011.04.028 · Cited by 99 · see citing works
Santana, M., Feeny, D. H., Johnson, J. A., McAlister, F. A., Kim, D., Weinkauf, J. G., & Lien, D. C. (2010) · Quality of Life Research · doi:10.1007/s11136-010-9599-3 · Cited by 96 · see citing works
Ratcliffe, J., Young, T. A., Longworth, L., & Buxton, M. J. (2005) · Value in Health · doi:10.1111/j.1524-4733.2005.03068.x · Cited by 17 · see citing works
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Basch, E., Deal, A. M., Dueck, A. C., Scher, H. I., Kris, M. G., Hudis, C., & Schrag, D. (2017) · JAMA · doi:10.1001/jama.2017.7156 · Cited by 2,302 · see citing works
Self-citationLheureux, S., Gourley, C., Vergote, I. B., & Oza, A. M. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32552-2 · Cited by 1,954 · see citing works
Integration of oncology and palliative care: a Lancet Oncology Commission
Kaasa, S., Loge, J. H., Aapro, M., Albreht, T., Anderson, R., Bruera, E. D., Brunelli, C., Caraceni, A. T., Cervantes, A. M. R., Currow, D. C., et al. (2018) · The Lancet Oncology · doi:10.1016/s1470-2045(18)30415-7 · Cited by 834 · see citing works
Şanlı, Ö., Dobruch, J. T., Knowles, M. A., Burger, M., Mehrdad Alemozaffar, A., Nielsen, M. E., & Lotan, Y. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.22 · Cited by 819 · see citing works
Management of Cancer Cachexia: ASCO Guideline
Roeland, E. J., Bohlke, K., Baracos, V. E., Bruera, E. D., Fabbro, E. D., Dixon, S., Fallon, M., Herrstedt, J., Lau, H., Platek, M., et al. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.00611 · Cited by 667 · see citing works
Patient-Reported Outcomes — Harnessing Patients’ Voices to Improve Clinical Care
Basch, E. (2017) · New England Journal of Medicine · doi:10.1056/nejmp1611252 · Cited by 637 · see citing works
Self-citationPatient-clinician communication: American Society of Clinical Oncology consensus guideline
Gilligan, T., Coyle, N., Frankel, R. M., Berry, D. L., Bohlke, K., Epstein, R. M., Finlay, E., Jackson, V. A., Lathan, C. S., Loprinzi, C. L., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.75.2311 · Cited by 610 · see citing works
Burstein, H. J., Krilov, L., Aragon‐Ching, J. B., Baxter, N. N., Chiorean, E. G., Chow, W. A., Groot, J. F. D., Devine, S. M., DuBois, S. G., El‐Deiry, W. S., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.71.5292 · Cited by 601 · see citing works
Greenhalgh, J., Gooding, K., Gibbons, E. J., Dalkin, S. M., Wright, J. M., Valderas, J. M., & Black, N. A. (2018) · Journal of Patient-Reported Outcomes · doi:10.1186/s41687-018-0061-6 · Cited by 597 · see citing works
Di Maio, M., Basch, E., Denis, F., Fallowfield, L. J., Ganz, P. A., Howell, D., Kowalski, C., Perrone, F., Stover, A. M., Sundaresan, P., et al. (2022) · Annals of Oncology · doi:10.1016/j.annonc.2022.04.007 · Cited by 509 · see citing works
Self-citationDenis, F., Lethrosne, C., Pourel, N., Molinier, O., Pointreau, Y., Domont, J., Bourgeois, H., Senellart, H., Trémolières, P., Lizée, T., et al. (2017) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/djx029 · Cited by 482 · see citing works
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Grossberg, A. J., Chu, L. C. H., Deig, C. R., Fishman, E. K., Hwang, W. L., Maitra, A., Marks, D. L., Mehta, A., Nabavizadeh, N., Simeone, D. M., et al. (2020) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21626 · Cited by 491 · see citing works
Hui, D., Hannon, B. L., Zimmermann, C., & Bruera, E. D. (2018) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21490 · Cited by 441 · see citing works
Basch, E., Schrag, D., Henson, S., Jansen, J., Ginos, B., Stover, A. M., Carr, P., Spears, P. A., Jonsson, M., Deal, A. M., et al. (2022) · JAMA · doi:10.1001/jama.2022.9265 · Cited by 413 · see citing works
Self-citationImplementation of Patient-Reported Outcomes in Routine Medical Care
Basch, E., Barbera, L. C., Kerrigan, C. L., & Velikova, G. (2018) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_200383 · Cited by 415 · see citing works
Self-citationGaertner, J., Siemens, W., Meerpohl, J. J., Antes, G., Meffert, C., Xander, C. J., Stock, S., Müeller, D., Schwarzer, G., & Becker, G. (2017) · BMJ · doi:10.1136/bmj.j2925 · Cited by 395 · see citing works
Henson, L. A., Maddocks, M. M., Evans, C., Davidson, M., Hicks, S., & Higginson, I. J. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.19.00470 · Cited by 381 · see citing works
Klopp, A. H., Yeung, A. R., Deshmukh, S., Gil, K. M., Wenzel, L. B., Westin, S. N., Gifford, K. A., Gaffney, D. K., Small, W. C., Thompson, S., et al. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2017.77.4273 · Cited by 368 · see citing works
Optimal pain management for patients with cancer in the modern era
Scarborough, B. M., & Smith, C. B. (2018) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21453 · Cited by 367 · see citing works
Nguyen, H., Butow, P., Dhillon, H., & Sundaresan, P. (2021) · Journal of Medical Radiation Sciences · doi:10.1002/jmrs.421 · Cited by 351 · see citing works
Financial toxicity in cancer care: Prevalence, causes, consequences, and reduction strategies
Lentz, R. W., Benson, A. B., & Kircher, S. M. (2019) · Journal of Surgical Oncology · doi:10.1002/jso.25374 · Cited by 337 · see citing works
Maximising the impact of patient reported outcome assessment for patients and society
Calvert, M., Kyte, D., Price, G., Valderas, J. M., & Hjollund, N. H. (2019) · BMJ · doi:10.1136/bmj.k5267 · Cited by 328 · see citing works
Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy
Absolom, K., Warrington, L., Hudson, E., Hewison, J., Morris, C., Holch, P., Carter, R., Gibson, A., Holmes, M., Clayton, B., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.02015 · Cited by 311 · see citing works
Guo, C., Ashrafian, H., Ghafur, S., Fontana, G., Gardner, C., & Prime, M. S. (2020) · npj Digital Medicine · doi:10.1038/s41746-020-00314-2 · Cited by 322 · see citing works
Digital health for optimal supportive care in oncology: benefits, limits, and future perspectives
Aapro, M., Bossi, P., Dasari, A. N., Fallowfield, L. J., Gascón, P., Geller, M. A., Jordan, K., Kim, J. W., Martin, K., & Porzig, S. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05539-1 · Cited by 318 · see citing works
Clinical trial design in the era of precision medicine
Fountzilas, E., Tsimberidou, A. M., Vo, H. H., & Kurzrock, R. (2022) · Genome Medicine · doi:10.1186/s13073-022-01102-1 · Cited by 326 · see citing works
Stover, A. M., Haverman, L., van Oers, H. A., Greenhalgh, J., Potter, C., Ahmed, S., Greenhalgh, J., Gibbons, E. J., Haverman, L., Manalili, K., et al. (2020) · Quality of Life Research · doi:10.1007/s11136-020-02564-9 · Cited by 313 · see citing works
Communication With Older Patients With Cancer Using Geriatric Assessment
Mohile, S. G., Epstein, R. M., Hurria, A., Heckler, C. E., Canin, B. E., Culakova, E., Duberstein, P. R., Gilmore, N. J., Xu, H., Plumb, S., et al. (2019) · JAMA Oncology · doi:10.1001/jamaoncol.2019.4728 · Cited by 302 · see citing works
Yang, L. Y., Manhas, D. S., Howard, A. F., & Olson, R. A. (2017) · Supportive Care in Cancer · doi:10.1007/s00520-017-3865-7 · Cited by 270 · see citing works
Maguire, R., McCann, L., Kotronoulas, G., Kearney, N., Ream, E., Armes, J., Patiraki, E., Furlong, E., Fox, P., Gaiger, A., et al. (2021) · BMJ · doi:10.1136/bmj.n1647 · Cited by 243 · see citing works
Nausea and vomiting of pregnancy and hyperemesis gravidarum
Fejzo, M. S., Trovik, J., Grooten, I. J., Sridharan, K., Roseboom, T. J., Vikanes, Å., Painter, R. C., & Mullin, P. M. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0110-3 · Cited by 306 · see citing works
The increasing value of eHealth in the delivery of patient-centred cancer care
Penedo, F. J., Oswald, L. B., Kronenfeld, J. P., Garcia, S. F., Cella, D., & Yanez, B. (2020) · The Lancet Oncology · doi:10.1016/s1470-2045(20)30021-8 · Cited by 252 · see citing works
Husson, O., de Rooij, B. H., Kieffer, J. M., Oerlemans, S., Mols, F., Aaronson, N. K., van der Graaf, W. T. A., & van de Poll-Franse, L. V. (2019) · The Oncologist · doi:10.1634/theoncologist.2019-0348 · Cited by 251 · see citing works
Patient-reported outcomes in cancer care — hearing the patient voice at greater volume
LeBlanc, T. W., & Abernethy, A. P. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2017.153 · Cited by 246 · see citing works
A Standard Set of Value-Based Patient-Centered Outcomes for Breast Cancer
Ong, W. L., Schouwenburg, M. G., van Bommel, A. C. M., Stowell, C. J., Allison, K. H., Benn, K., Browne, J. P., Cooter, R. D., Delaney, G. P., Duhoux, F. P., et al. (2016) · JAMA Oncology · doi:10.1001/jamaoncol.2016.4851 · Cited by 243 · see citing works
S3-Leitlinie – Kolorektales Karzinom
Schmiegel, W., Buchberger, B., Follmann, M., Graeven, U., Heinemann, V., Langer, T. G., Nothacker, M., Porschen, R., Rödel, C. M., Rösch, T., et al. (2017) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0043-121106 · Cited by 242 · see citing works
Patient reported outcome measures in rare diseases: a narrative review
Slade, A. L., Isa, F., Kyte, D. G., Pankhurst, T., Kerecuk, L., Ferguson, J., Lipkin, G. W., & Calvert, M. (2018) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-018-0810-x · Cited by 240 · see citing works
Health-Related Quality of Life
Sitlinger, A. P., & Zafar, S. Y. (2018) · Surgical Oncology Clinics of North America · doi:10.1016/j.soc.2018.05.008 · Cited by 248 · see citing works
Nipp, R. D., El‐Jawahri, A., Moran, S. M., D'Arpino, S. M., Johnson, P. C., Lage, D. E., Wong, R. L., Pirl, W. F., Traeger, L., Lennes, I. T., et al. (2017) · Cancer · doi:10.1002/cncr.30912 · Cited by 230 · see citing works
Identifying the most prevalent unmet needs of cancer survivors in Australia: A systematic review
Lisy, K., Langdon, L., Piper, A., & Jefford, M. (2019) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/ajco.13176 · Cited by 215 · see citing works
Reck, M., Schenker, M., Lee, K. H., Provencio, M., Nishio, M., Leśniewski-Kmak, K., Sangha, R. S., Ahmed, S. I., Raimbourg, J., Feeney, K., et al. (2019) · European Journal of Cancer · doi:10.1016/j.ejca.2019.05.008 · Cited by 215 · see citing works
Mooney, K. H., Beck, S. L., Wong, B. G., Dunson, W., Wujcik, D. M., Whisenant, M., & Donaldson, G. W. (2017) · Cancer Medicine · doi:10.1002/cam4.1002 · Cited by 210 · see citing works
Sidey-Gibbons, C. J., Porter, I. H., Gonçalves, D. C., Stoilov, S., Ricci‐Cabello, I., Tsangaris, E., Gangannagaripalli, J., Davey, A. F., Gibbons, E. J., Kotzeva, A., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011589.pub2 · Cited by 209 · see citing works
Basch, E., Stover, A. M., Schrag, D., Chung, A., Jansen, J., Henson, S., Carr, P., Ginos, B., Deal, A., Spears, P. A., et al. (2020) · JCO Clinical Cancer Informatics · doi:10.1200/cci.20.00081 · Cited by 194 · see citing works
Self-citationTimely Palliative Care: Personalizing the Process of Referral
Hui, D., Heung, Y. J., & Bruera, E. D. (2022) · Cancers · doi:10.3390/cancers14041047 · Cited by 213 · see citing works
Incorporating the patient experience into regulatory decision making in the USA, Europe, and Canada
Kluetz, P. G., O’Connor, D. J., & Soltys, K. M. (2018) · The Lancet Oncology · doi:10.1016/s1470-2045(18)30097-4 · Cited by 199 · see citing works
Graupner, C., Kimman, M., Mul, S., Slok, A. H. M., Claessens, D., Kleijnen, J., Dirksen, C. D., & Breukink, S. O. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05695-4 · Cited by 195 · see citing works
Development and validation of an interpretive guide for PROMIS scores
Rothrock, N. E., Amtmann, D., & Cook, K. F. (2020) · Journal of Patient-Reported Outcomes · doi:10.1186/s41687-020-0181-7 · Cited by 194 · see citing works
Warrington, L., Absolom, K. L., Conner, M. T., Kellar, I., Clayton, B., Ayres, M., & Velikova, G. (2018) · Journal of Medical Internet Research · doi:10.2196/10875 · Cited by 200 · see citing works
Symptom Burden in the First Year After Cancer Diagnosis: An Analysis of Patient-Reported Outcomes
Bubis, L. D., Davis, L., Mahar, A., Barbera, L., Li, Q., Moody, L., Karanicolas, P., Sutradhar, R., & Coburn, N. G. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2017.76.0876 · Cited by 187 · see citing works
Content validity of the EORTC quality of life questionnaire QLQ-C30 for use in cancer
Cocks, K., Wells, J. R., Johnson, C. A., Schmidt, H., Koller, M. T., Oerlemans, S., Velikova, G., Pinto, M., Tomaszewski, K. A., Aaronson, N. K., et al. (2022) · European Journal of Cancer · doi:10.1016/j.ejca.2022.10.026 · Cited by 195 · see citing works
The Lancet Breast Cancer Commission
Coles, C. E., Earl, H. M., Anderson, B. O., Barrios, C. H., Bienz, M., Bliss, J. M., Cameron, D., Cardoso, F., Cui, W., Francis, P. A., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)00747-5 · Cited by 198 · see citing works
Alfano, C. M., Leach, C. R., Smith, T. G., Miller, K. D., Alcaraz, K. I., Cannady, R. S., Wender, R. C., & Brawley, O. W. (2019) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21548 · Cited by 179 · see citing works
Mack, J. W., McFatrich, M., Withycombe, J. S., Maurer, S. H., Jacobs, S. S., Lin, L., Lucas, N. R., Baker, J. N., Mann, C. M., Sung, L., et al. (2020) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2020.2861 · Cited by 188 · see citing works
Ishaque, S., Karnon, J. D., Chen, G., Nair, R., & Salter, A. B. (2018) · Quality of Life Research · doi:10.1007/s11136-018-2016-z · Cited by 181 · see citing works
The Future of Wearable Technologies and Remote Monitoring in Health Care
Liao, Y., Thompson, C. A., Peterson, S. K., Mandrola, J. M., & Beg, M. S. (2019) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_238919 · Cited by 180 · see citing works
Maguire, R., Fox, P. A., McCann, L., Miaskowski, C. A., Kotronoulas, G., Miller, M., Furlong, E., Ream, E., Armes, J., Patiraki, E. I., et al. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-015016 · Cited by 172 · see citing works
Scotté, F., Bossi, P., Carola, É., Cudennec, T., Dielenseger, P., Gomes, F., Knox, S., & Strasser, F. (2018) · Annals of Oncology · doi:10.1093/annonc/mdy228 · Cited by 171 · see citing works
The Value and Future Developments of Multidisciplinary Team Cancer Care
Selby, P. J., Popescu, R. A., Lawler, M., Butcher, H., & Costa, A. (2019) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_236857 · Cited by 176 · see citing works
Mitigating acute chemotherapy-associated adverse events in patients with cancer
Kuderer, N. M., Desai, A. P., Lustberg, M. B., & Lyman, G. H. (2022) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-022-00685-3 · Cited by 173 · see citing works
Thomas, M. B., Jones, P. G., Arnold, S. V., & Spertus, J. A. (2021) · JAMA Cardiology · doi:10.1001/jamacardio.2020.7478 · Cited by 166 · see citing works
Benefits of mobile apps in pain management: Systematic review
Thurnheer, S. E., Gravestock, I., Pichierri, G., Steurer, J., & Burgstaller, J. M. (2018) · JMIR mHealth and uHealth · doi:10.2196/11231 · Cited by 160 · see citing works
Efficace, F., Collins, P. G. S., Cottone, F., Giesinger, J. M., Sommer, K., Anota, A., Schlüssel, M. M., Fazi, P., & Vignetti, M. (2021) · Value in Health · doi:10.1016/j.jval.2020.10.017 · Cited by 156 · see citing works
Mir, O., Ferrua, M., Fourcade, A., Mathivon, D., Duflot-Boukobza, A., Dumont, S., Baudin, É., Delaloge, S., Malka, D., Albiges, L. K., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01788-1 · Cited by 153 · see citing works
Garg, S., Williams, N. L., Ip, A., & Dicker, A. P. (2018) · JCO Clinical Cancer Informatics · doi:10.1200/cci.17.00159 · Cited by 154 · see citing works
Implementing Patient-Reported Outcome Measures in Clinical Breast Cancer Care: A Systematic Review
van Egdom, L. S. E., Oemrawsingh, A., Verweij, L. M., Lingsma, H. F., Koppert, L. B., Verhoef, C. K., Klazinga, N., & Hazelzet, J. A. (2019) · Value in Health · doi:10.1016/j.jval.2019.04.1927 · Cited by 151 · see citing works
Cheville, A. L., Moynihan, T., Herrin, J., Loprinzi, C., & Kroenke, K. (2019) · JAMA Oncology · doi:10.1001/jamaoncol.2019.0011 · Cited by 143 · see citing works
Cost-Effectiveness of Web-Based Patient-Reported Outcome Surveillance in Patients With Lung Cancer
Lizee, T., Basch, E., Tremolieres, P., Voog, É., Dômont, J., Peyraga, G., Urban, T., Bennouna, J., Septans, A.-L., Balavoine, M., et al. (2019) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2019.02.005 · Cited by 142 · see citing works
Self-citationHughes, S., Haroon, S., Subramanian, A., McMullan, C., Aiyegbusi, O. L., Turner, G. M., Jackson, L., Davies, E. H., Frost, C., McNamara, G., et al. (2022) · BMJ · doi:10.1136/bmj-2022-070230 · Cited by 142 · see citing works
Rugo, H. S., O’Shaughnessy, J., Boyle, F. M., Toi, M., Broom, R. J., Blancas, I., Gümüş, M., Yamashita, T., Im, Y.-H., Rastogi, P., et al. (2022) · Annals of Oncology · doi:10.1016/j.annonc.2022.03.006 · Cited by 142 · see citing works
Aiyegbusi, O. L., Kyte, D. G., Cockwell, P., Marshall, T. P., Gheorghe, A., Keeley, T., Slade, A. L., & Calvert, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179733 · Cited by 139 · see citing works
Innovations in research and clinical care using patient‐generated health data
Jim, H., Hoogland, A. I., Brownstein, N. C., Barata, A., Dicker, A. P., Knoop, H., Gonzalez, B. D., Perkins, R. M., Rollison, D. E. M., Gilbert, S. M., et al. (2020) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21608 · Cited by 141 · see citing works
Thanarajasingam, G., Minasian, L. M., Baron, F., Cavalli, F., de Claro, R. A., Dueck, A. C., El‐Galaly, T. C., Everest, N., Geißler, J., Gisselbrecht, C., et al. (2018) · The Lancet Haematology · doi:10.1016/s2352-3026(18)30051-6 · Cited by 138 · see citing works
Self-citationMobile health technology: a novel tool in chronic disease management
Fan, K., & Zhao, Y. (2021) · Intelligent Medicine · doi:10.1016/j.imed.2021.06.003 · Cited by 144 · see citing works
Patient-Reported Outcomes for Breast Cancer
Tevis, S. E. A., James, T. A., Kuerer, H. M., Pusic, A. L., Yao, K. A., Merlino, J. I., & Dietz, J. R. (2018) · Annals of Surgical Oncology · doi:10.1245/s10434-018-6616-1 · Cited by 136 · see citing works
Lu, Z., Fang, Y., Liu, C. X., Zhang, X., Xin, X., He, Y., Cao, Y., Jiao, X., Sun, T., Pang, Y. K., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.01254 · Cited by 136 · see citing works
Best Practices for Reducing Unplanned Acute Care for Patients With Cancer
Handley, N. R., Schuchter, L. M., & Bekelman, J. E. (2018) · Journal of Oncology Practice · doi:10.1200/jop.17.00081 · Cited by 137 · see citing works
Mehrotra, R., Davison, S. N., Farrington, K., Flythe, J. E., Foo, M., Madero, M., Morton, R. L., Tsukamoto, Y., Unruh, M. L., Cheung, M., et al. (2023) · Kidney International · doi:10.1016/j.kint.2023.05.019 · Cited by 135 · see citing works
Patient-reported outcome measures (PROMs) in the management of lung cancer: A systematic review
Bouazza, Y. B., Chiairi, I., Kharbouchi, O. E., Backer, L. D., Vanhoutte, G., Janssens, A., & van Meerbeeck, J. P. (2017) · Lung Cancer · doi:10.1016/j.lungcan.2017.09.011 · Cited by 134 · see citing works
Zerillo, J. A., Schouwenburg, M. G., van Bommel, A. C. M., Stowell, C. J., Lippa, J., Bauer, D., Berger, A. M., Boland, G., Borràs, J. M., Buss, M. K., et al. (2017) · JAMA Oncology · doi:10.1001/jamaoncol.2017.0417 · Cited by 133 · see citing works
Fred Saad, C., Cella, D. F., Basch, E., Hadaschik, B. A., Mainwaring, P. N., Oudard, S. M., Graff, J. N., McQuarrie, K., Li, S., Hudgens, S. A., et al. (2018) · The Lancet Oncology · doi:10.1016/s1470-2045(18)30456-x · Cited by 130 · see citing works
Self-citationCarfora, L., Foley, C. M., Hagi-Diakou, P., Lesty, P. J., Sandstrom, M. L., Ramsey, I., & Kumar, S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267030 · Cited by 131 · see citing works
Addressing the needs of cancer survivors during the COVID-19 pandemic.
Nekhlyudov, L., Duijts, S., Hudson, S. V., Jones, J. M., Keogh, J., Love, B., Lustberg, M., Smith, K. C., Tevaarwerk, A., Yu, X., et al. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-020-00884-w · Cited by 130 · see citing works
Sullivan, D. R., Iyer, A. S., Enguidanos, S. M., Cox, C. E., Farquhar, M. C., Janssen, D. J. A., Lindell, K. O., Mularski, R. A., Smallwood, N., Turnbull, A. E., et al. (2022) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202207-1262st · Cited by 134 · see citing works
Patient-Reported Outcome Measures in Cancer Care
Balitsky, A. K., Rayner, D. G., Britto, J., Lionel, A. C., Ginsberg, L., Cho, W., Wilfred, A. M., Sardar, H., Cantor, N., Mian, H. S., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.24793 · Cited by 134 · see citing works
Bonsel, J. M., Itiola, A. J., Huberts, A. S., Bonsel, G. J., & Penton, H. (2024) · Health and Quality of Life Outcomes · doi:10.1186/s12955-024-02312-4 · Cited by 128 · see citing works
Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments
Dupuis, L. L., Johnston, D. L., Baggott, C., Hyslop, S., Tomlinson, D., Gibson, P. J., Orsey, A. D., Dix, D. B., Price, V., Vanan, M., et al. (2017) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djx250 · Cited by 127 · see citing works
Solassol, I., Pinguet, F., & Quantin, X. (2019) · Biomolecules · doi:10.3390/biom9110668 · Cited by 123 · see citing works
Henneghan, A. M., Dyk, K. V., Kaufmann, T. L., Harrison, R. A., Sidey-Gibbons, C. J., Heijnen, C. J., & Kesler, S. R. (2021) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djab027 · Cited by 122 · see citing works
Holch, P., Warrington, L., Bamforth, L., Keding, A., Ziegler, L. E., Absolom, K. L., Hector, C., Harley, C., Johnson, O. A., Hall, G. D., et al. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx317 · Cited by 121 · see citing works
Relevance of randomised controlled trials in oncology
Tannock, I. F., Amir, E., Booth, C. M., Niraula, S., Ocaña, A., Šeruga, B., Templeton, A. J., & Vera-Badillo, F. (2016) · The Lancet Oncology · doi:10.1016/s1470-2045(16)30572-1 · Cited by 119 · see citing works
A Systematic Review of Clinical Decision Support Systems for Clinical Oncology Practice
Pawloski, P. A., Brooks, G. A., Nielsen, M. E., & Olson‐Bullis, B. A. (2019) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.7104 · Cited by 119 · see citing works
Alfano, C. M., Jefford, M., Maher, J., Birken, S. A., & Mayer, D. K. (2019) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_238267 · Cited by 120 · see citing works
Muscaritoli, M., Arends, J., & Aapro, M. (2019) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758835919880084 · Cited by 140 · see citing works
Fjell, M., Langius‐Eklöf, A., Nilsson, M. I., Wengström, Y., & Sundberg, K. K. (2020) · The Breast · doi:10.1016/j.breast.2020.03.004 · Cited by 119 · see citing works
Barbera, L., Sutradhar, R., Seow, H., Mittmann, N., Howell, D., Earle, C. C., Li, Q., & Thiruchelvam, D. (2020) · Cancer Medicine · doi:10.1002/cam4.3374 · Cited by 111 · see citing works
Dai, W., Feng, W., Zhang, Y., Wang, X. S., Liu, Y., Pompili, C., Xu, W., Xie, S.-H., Wang, Y., Liao, J. X., et al. (2022) · Journal of Clinical Oncology · doi:10.1200/jco.21.01344 · Cited by 120 · see citing works
Bunevičienė, I., Mekary, R. A., Smith, T. R., Onnela, J.-P. “., & Bunevičius, A. (2020) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2020.103123 · Cited by 115 · see citing works
Anatchkova, M., Donelson, S. M., Skalicky, A. M., McHorney, C. A., Jagun, D., & Whiteley, J. (2018) · Journal of Patient-Reported Outcomes · doi:10.1186/s41687-018-0091-0 · Cited by 111 · see citing works
Crafoord, M.-T., Fjell, M., Sundberg, K. K., Nilsson, M. I., & Langius‐Eklöf, A. (2020) · Journal of Medical Internet Research · doi:10.2196/17058 · Cited by 112 · see citing works
- Authors
- Basch, E., Deal, A. M., Kris, M. G., Scher, H. I., Hudis, C. A., Sabbatini, P., Rogak, L., Bennett, A. V., Dueck, A. C., Atkinson, T. M., Chou, J. F., Dulko, D., Sit, L., Barz, A., Novotny, P., Fruscione, M., Sloan, J. A., & Schrag, D.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Ethan Basch, Mark G. Kris, Howard I. Scher, Clifford A. Hudis, Paul Sabbatini, Lauren Rogak, Thomas M. Atkinson, Joanne F. Chou, Dorothy Dulko, Laura Sit, Michael Fruscione, and Deborah Schrag, Memorial Sloan Kettering Cancer Center, New York, NY; Ethan Basch, Allison M. Deal, and Antonia V. Bennett, University of North Carolina, Chapel Hill, NC; Amylou C. Dueck, Mayo Clinic, Scottsdale, AZ; Allison Barz, Children’s Hospital of Philadelphia, Philadelphia, PA; Paul Novotny and Jeff A. Sloan, Mayo Clinic,...
- ORCID
- Venue
- Journal of Clinical Oncology
- Published
- 2016-02-20
- Volume
- 34
- Issue
- 6
- Pages
- 557-565
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- PMC
- PMC4872028
- OpenAlex
- W2195040438
- Cited by
- 2,593
- References
- 36
- Citations by year
- 2026: 252 · 2025: 263 · 2024: 321 · 2023: 288 · 2022: 316 · 2021: 299 · 2020: 292 · 2019: 191 · 2018: 180 · 2017: 143 · 2016: 44 · 2015: 3
- FWCI
- 53.87
- Type
- journal article
- Language
- en
- Update notices
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Memorial Sloan-Kettering Cancer Center
- Society of Memorial Sloan Kettering
- National Cancer Institute (P30CA008748, P30CA015083, P30CA016086)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- patient-reported outcomes, symptom monitoring, cancer chemotherapy, health-related quality of life, advanced solid tumors, e-mail alerts, emergency department visits, hospitalization, survival, quality-adjusted survival, computer literacy, outpatient oncology
- MeSH terms
- Adult, Aged, Aged, 80 and over, Ambulatory Care, Antineoplastic Agents, Emergency Service, Hospital, Female, Hospitalization, Humans, Male, Middle Aged, Neoplasms, Quality of Life, Survival Rate, Internet, Nurse's Role, Electronic Mail, Self Report, Symptom Assessment
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