Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 332

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo guidelines

Open access
Kiriyama, Seiki, Takada, Tadahiro, Strasberg, Steven M., Solomkin, Joseph S., Mayumi, Toshihiko, Pitt, Henry A., Gouma, Dirk J., Garden, O. James, Büchler, Markus W., Yokoe, Masamichi, Kimura, Yasutoshi, Tsuyuguchi, Toshio, Itoi, Takao, Yoshida, Masahiro, Miura, Fumihiko, Yamashita, Yuichi, Okamoto, Kohji, Gabata, Toshifumi, Hata, Jiro, Higuchi, Ryota, Windsor, John A., Bornman, Philippus C., Fan, Sheung‐Tat, Singh, Harijt, de Santibanes, Eduardo, Gomi, Harumi, Kusachi, Shinya, Murata, Atsuhiko, Chen, Xiao‐Ping, Jagannath, Palepu, Lee, Sung Gyu, Padbury, Robert, Chen, Miin‐Fu·2012·Journal of Hepato-Biliary-Pancreatic Sciences
DOI 10.1007/s00534-012-0537-3
Open this paper in CoChat — free account

Abstract

Background: The Tokyo Guidelines for the management of acute cholangitis and cholecystitis were published in 2007 (TG07) and have been widely cited in the world literature. Because of new information that has been published since 2007, we organized the Tokyo Guidelines Revision Committee to conduct a multicenter analysis to develop the updated Tokyo Guidelines (TG13). Methods/materials: We retrospectively analyzed 1,432 biliary disease cases where acute cholangitis was suspected. The cases were collected from multiple tertiary care centers in Japan. The ‘gold standard’ for acute cholangitis in this study was that one of the three following conditions was present: (1) purulent bile was observed; (2) clinical remission following bile duct drainage; or (3) remission was achieved by antibacterial therapy alone, in patients in whom the only site of infection was the biliary tree. Comparisons were made for the validity of each diagnostic criterion among TG13, TG07 and Charcot's triad. Results: The major changes in diagnostic criteria of TG07 were re‐arrangement of the diagnostic items and exclusion of abdominal pain from the diagnostic list. The sensitivity improved from 82.8 % (TG07) to 91.8 % (TG13). While the specificity was similar to TG07, the false positive rate in cases of acute cholecystitis was reduced from 15.5 to 5.9 %. The sensitivity of Charcot's triad was only 26.4 % but the specificity was 95.6 %. However, the false positive rate in cases of acute cholecystitis was 11.9 % and not negligible. As for severity grading, Grade II (moderate) acute cholangitis is defined as being associated with any two of the significant prognostic factors which were derived from evidence presented recently in the literature. The factors chosen allow severity assessment to be performed soon after diagnosis of acute cholangitis. Conclusion: TG13 present a new standard for the diagnosis, severity grading, and management of acute cholangitis.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s00534-012-0537-3

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 25 references

Cited by

See all 332

Metadata

Authors
Kiriyama, S., Takada, T., Strasberg, S. M., Solomkin, J. S., Mayumi, T., Pitt, H. A., Gouma, D. J., Garden, O. J., Büchler, M. W., Yokoe, M., Kimura, Y., Tsuyuguchi, T., Itoi, T., Yoshida, M., Miura, F., Yamashita, Y., Okamoto, K., Gabata, T., Hata, J., Higuchi, R., Windsor, J. A., Bornman, P. C., Fan, S., Singh, H., de Santibanes, E., Gomi, H., Kusachi, S., Murata, A., Chen, X., Jagannath, P., Lee, S. G., Padbury, R., & Chen, M.
Venue
Journal of Hepato-Biliary-Pancreatic Sciences
Publisher
Wiley
Published
2012-07-24
Volume
19
Issue
5
Pages
548-556
ISSN
  • 1868-6974 (ISSN-L)
  • 1868-6982
DOI
10.1007/s00534-012-0537-3
OpenAlex
W2127121625
Cited by
332
References
25
FWCI
22.77
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo guidelines. https://app.cochat.ai/papers/10.1007/s00534-012-0537-3
The paper
Kiriyama, S., Takada, T., Strasberg, S. M., Solomkin, J. S., Mayumi, T., Pitt, H. A., Gouma, D. J., Garden, O. J., Büchler, M. W., Yokoe, M., Kimura, Y., Tsuyuguchi, T., Itoi, T., Yoshida, M., Miura, F., Yamashita, Y., Okamoto, K., Gabata, T., Hata, J., . . . Chen, M. (2012). New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo guidelines. Journal of Hepato-Biliary-Pancreatic Sciences. https://doi.org/10.1007/s00534-012-0537-3

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.