Review of the pathological results of 2660 appendicectomy specimens
Abstract
Purpose Appendicitis is the most commonly performed emergency abdominal surgery. The appendix can also be the site of a variety of neoplasms and unusual inflammatory conditions. A retrospective review was performed to determine the pathological diagnoses in appendicectomy specimens. Methods This study is a retrospective analysis of 2660 appendicectomies performed from 1997 to 2003. The reports were analyzed for the following parameters: age-related incidence of acute appendicitis, seasonal variation in presentation, perforation rate, rate of negative and incidental appendicectomy, and the incidence of other pathologies encountered. Results Of the 2660 appendicectomy specimens, acute appendicitis was seen in 1718 patients (64.58%), with a peak in patients in their second decade (35.09% of cases of acute appendicitis). The perforation rate was 13.9% and was significantly higher in patients aged 70 years or more (P Conclusions The high rate of negative appendicectomy among female patients and the increased incidence of perforation in elderly patients reinforce the validity of the judicious use of laparoscopy in these populations. There are still a number of unusual histologies found in appendicectomy specimens supporting the continued use of routine histology.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Negative appendectomy (histologically normal appendix despite clinical suspicion of appendicitis) has been reported in 10% to 20% of cases, and up to 30% in specific populations such as young women and children.
“This phenomenon, often referred to as a “negative appendectomy,” has been reported in 10% to 20% of cases, and up to 30% in specific populations such as young women and children [33,34].”
From Selective Appendectomy in Patients Undergoing Minimally Invasive Surgery for Endometriosis: A Retrospective Cohort Study (2025) · cites this paper as [34]
Cites
Chapman, C. B. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92882-2 · Cited by 338 · see citing works
Imaging for Suspected Appendicitis: Negative Appendectomy and Perforation Rates
Bendeck, S. E., Nino‐Murcia, M., Berry, G. J., & Jeffrey, R. B. (2002) · Radiology · doi:10.1148/radiol.2251011780 · Cited by 217 · see citing works
High negative appendectomy rates are no longer acceptable
Colson, M., Skinner, K. A., & Dunnington, G. L. (1997) · The American Journal of Surgery · doi:10.1016/s0002-9610(97)00183-9 · Cited by 146 · see citing works
Review of the pathologic diagnoses of 2,216 appendectomy specimens
Blair, N. P., Bugis, S. P., Turner, L. J., & MacLeod, M. M. (1993) · The American Journal of Surgery · doi:10.1016/s0002-9610(05)80446-5 · Cited by 115 · see citing works
Laparoscopic appendectomy—is it worthwhile?
Laine, S., Rantala, A., Gullichsen, R., & Ovaska, J. T. (1997) · Surgical Endoscopy · doi:10.1007/s004649900305 · Cited by 109 · see citing works
Pathology of tropical appendicitis.
Gupta, S. C., Gupta, A. K., Keswani, N. K., Singh, P. A., Tripathi, A. K., & Krishna, V. (1989) · Journal of Clinical Pathology · doi:10.1136/jcp.42.11.1169 · Cited by 95 · see citing works
Acute appendicitis—a clear-cut case in men, a guessing game in young women
Borgstein, P. J., Gordijn, R. V., Eijsbouts, Q. A. J., & Cuesta, M. A. (1997) · Surgical Endoscopy · doi:10.1007/s004649900488 · Cited by 88 · see citing works
YERSINIA INFECTION AND ACUTE ABDOMINAL PAIN
Attwood, S., Cafferkey, M., West, A., Healy, E., Mealy, K., Buckley, T. F., Boyle, N., & Keane, F. B. V. (1987) · The Lancet · doi:10.1016/s0140-6736(87)90175-9 · Cited by 76 · see citing works
Is the incidence of acute appendicitis really falling?
Williams, N. M., Jackson, D., Everson, N. W., & Johnstone, J. M. (1998) · PubMed Central · Cited by 59 · see citing works
Review of the histopathological findings in appendices removed for acute appendicitis in Nigerians.
Ojo, O. S., Udeh, S. C., & Odesanmi, W. O. (1991) · PubMed · Cited by 57 · see citing works
Acute appendicitis. A 5-year review.
Ricci, M. A., Trevisani, M. F., & Beck, W. C. (1991) · PubMed · Cited by 52 · see citing works
Diverticulosis of the vermiform appendix
Wetzig, N. R. (1986) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1986.tb113876.x · Cited by 52 · see citing works
Appendicitis is a place for clinical judgement
Bergeron, É., Richer, B., Gharib, R., & Giard, A. (1999) · The American Journal of Surgery · doi:10.1016/s0002-9610(99)00092-6 · Cited by 47 · see citing works
Abdominal pain as a cause of acute admission to hospital.
Hawthorn, I. E. (1992) · PubMed · Cited by 43 · see citing works
Rypins, E. B., Kipper, S. L., Weiland, F. L., Neal, C., Line, B. R., McDonald, R., Klonecke, A. S., Barron, B. J., Palestro, C. J., Waxman, A. D., et al. (2002) · Annals of Surgery · doi:10.1097/00000658-200202000-00011 · Cited by 37 · see citing works
Stability in Incidence of Acute Appendicitis
Kørner, H., Søreide, J. A., Pedersen, E. J., Bru, T., Søndenaa, K., & VATTEN, L. J. (2001) · Digestive Surgery · doi:10.1159/000050099 · Cited by 37 · see citing works
Improving diagnosis of acute appendicitis with atypical findings by Tc-99m HMPAO leukocyte scan
Shung-Shung, S., Yu-Chien, S., Mei-Due, Y., Hwei-Chung, W., & Kao, A. (2002) · Nuklearmedizin - NuclearMedicine · doi:10.1055/s-0038-1623994 · Cited by 4 · see citing works
[Acute appendicitis in advanced age].
Hr, Z., & Hj, M. (1998) · PubMed · Cited by 4 · see citing works
[Acute appendicitis in advanced age].
De Sanctis, C. (1950) · PubMed · Cited by 2 · see citing works
Buchholz, J., Mayer, M., Krawzak, H.-W., & Kruse, F. H. (1991) · PubMed · Cited by 2 · see citing works
[Characteristics of appendicitis in patients over 70 years of age].
Klinnert, J., Boese-Landgraf, J., & Lc, T. (1998) · PubMed · Cited by 2 · see citing works
Flagged first, then by citations
1 of the 22 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Appendiceal neoplasms and pseudomyxoma peritonei: A population based study
Smeenk, R. M., van Velthuysen, M. F., Verwaal, V. J., & Zoetmulder, F. A. N. (2007) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2007.04.002 · Cited by 557 · see citing works
Diagnosis and management of acute appendicitis. EAES consensus development conference 2015
Gorter, R. R., Eker, H. H., Gorter-Stam, M., Abis, G. S. A., Acharya, A., Ankersmit, M., Antoniou, S. A., Arolfo, S., Babic, B., Boni, L., et al. (2016) · Surgical Endoscopy · doi:10.1007/s00464-016-5245-7 · Cited by 493 · see citing works
Baird, D. L. H., Simillis, C., Kontovounisios, C., Rasheed, S., & Tekkis, P. P. (2017) · BMJ · doi:10.1136/bmj.j1703 · Cited by 191 · see citing works
Akbulut, S. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i15.1961 · Cited by 179 · see citing works
Diverticulosis and Diverticulitis of the Appendix
AbdullGaffar, B. (2009) · International Journal of Surgical Pathology · doi:10.1177/1066896909332728 · Cited by 152 · see citing works
Evaluation of the Appendicitis Inflammatory Response Score for Patients with Acute Appendicitis
de Castro, S. M. M., Ünlü, Ç., Steller, E. P., van Wagensveld, B. A., & Vrouenraets, B. C. (2012) · World Journal of Surgery · doi:10.1007/s00268-012-1521-4 · Cited by 147 · see citing works
Fugazzola, P., Ceresoli, M., Agnoletti, V., Agresta, F., Amato, B., Carcoforo, P., Catena, F., Chiara, O., Chiarugi, M., Cobianchi, L., et al. (2020) · World Journal of Emergency Surgery · doi:10.1186/s13017-020-00298-0 · Cited by 141 · see citing works
Role of the faecolith in modern-day appendicitis
Singh, J., & Mariadason, J. G. (2012) · Annals of The Royal College of Surgeons of England · doi:10.1308/003588413x13511609954851 · Cited by 124 · see citing works
Histopathological findings in appendectomy specimens: a study of 24,697 cases
Charfi, S., Sellami, A., Affes, A., Yaïch, K., Mzali, R., & Boudawara, T. S. (2014) · International Journal of Colorectal Disease · doi:10.1007/s00384-014-1934-7 · Cited by 111 · see citing works
Chamisa, I. (2009) · Annals of The Royal College of Surgeons of England · doi:10.1308/003588409x12486167521677 · Cited by 110 · see citing works
The value of routine histopathological examination of appendicectomy specimens
Jones, A. E., Phillips, A. W., Jarvis, J. R., & Sargen, K. (2007) · BMC Surgery · doi:10.1186/1471-2482-7-17 · Cited by 106 · see citing works
Mucocele of the Appendix: Case Report and Review of Literature
Demetrashvili, Z., Chkhaidze, M., Khutsishvili, K., Topchishvili, G., Javakhishvili, T., Pipia, I., & Qerqadze, V. (2012) · International Surgery · doi:10.9738/cc139.1 · Cited by 94 · see citing works
Predicting appendiceal tumors among patients with appendicitis
Loftus, T. J., Raymond, S. L., Sarosi, G. A., Croft, C. A., Smith, R. S., Efron, P. A., Moore, F. A., Brakenridge, S. C., Mohr, A. M., & Jordan, J. R. (2017) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000001378 · Cited by 91 · see citing works
Multiple regression model to analyze the total LOS for patients undergoing laparoscopic appendectomy
Trunfio, T. A., Scala, A., Giglio, C., Rossi, G., Borrelli, A., Romano, M., & Improta, G. (2022) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-022-01884-9 · Cited by 89 · see citing works
Pathologies of the appendix: a 10‐year review of 4670 appendicectomy specimens
Chandrasegaram, M. D., Rothwell, L. A., An, E. I., & Miller, R. J. (2012) · ANZ Journal of Surgery · doi:10.1111/j.1445-2197.2012.06185.x · Cited by 86 · see citing works
Nielsen, J. W., Boomer, L. A., Kurtovic, K. J., Lee, E., Kupzyk, K. A., Mallory, R., Adler, B. H., Bates, D. G., & Kenney, B. D. (2014) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2014.10.033 · Cited by 85 · see citing works
Emre, A., Akbulut, S., Bozdağ, Z., Yilmaz, M., Kanlıöz, M., Emre, R., & Şahin, N. (2013) · International Surgery · doi:10.9738/intsurg-d-13-00098.1 · Cited by 81 · see citing works
Stein, G. Y., Rath‐Wolfson, L., Zeidman, A., Atar, E., Marcus, O., Joubran, S., & Ram, E. (2012) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-012-0958-0 · Cited by 78 · see citing works
Yeh, C.-C., Wu, S., Liao, C., Su, L.-T., Hsieh, C.-H., & Li, T. (2011) · Surgical Endoscopy · doi:10.1007/s00464-011-1645-x · Cited by 75 · see citing works
Adenocarcinoma of the Appendix Is Rarely Detected by Colonoscopy
Trivedi, A. N., Levine, E. A., & Mishra, G. (2008) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-008-0774-6 · Cited by 74 · see citing works
Volante, M., Daniele, L., Asioli, S., Cassoni, P., Comino, A., Coverlizza, S., Giuli, P. D., Fava, C., Manini, C., Berruti, A., et al. (2013) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e318275d1d7 · Cited by 68 · see citing works
Evaluation of scoring systems in predicting acute appendicitis in children
Macco, S., Vrouenraets, B. C., & de Castro, S. M. M. (2016) · Surgery · doi:10.1016/j.surg.2016.06.023 · Cited by 68 · see citing works
Review Article: Granulomatous Diseases and Granulomas of the Appendix
AbdullGaffar, B. (2010) · International Journal of Surgical Pathology · doi:10.1177/1066896909349246 · Cited by 67 · see citing works
Peltrini, R., Cantoni, V., Green, R., Lionetti, R., D’Ambra, M., Bartolini, C., Luca, M. D., Bracale, U. M., Cuocolo, A., & Corcione, F. (2021) · The Surgeon · doi:10.1016/j.surge.2021.01.010 · Cited by 64 · see citing works
Incidence and outcomes of unexpected pathology findings after appendectomy
Alemayehu, H., Snyder, C. L., Peter, S. D. S., & Ostlie, D. J. (2014) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2014.01.005 · Cited by 55 · see citing works
Swank, H. A., Eshuis, E. J., Ubbink, D. T., & Bemelman, W. A. (2010) · Colorectal Disease · doi:10.1111/j.1463-1318.2010.02457.x · Cited by 54 · see citing works
Safety and feasibility of laparoscopic surgery for appendiceal mucocele: a multicenter study
Kim, T. K., Park, J. H., Kim, J. Y., Kim, B. C., Kang, B. M., Min, S. K., & Kim, J. W. (2018) · Surgical Endoscopy · doi:10.1007/s00464-018-6182-4 · Cited by 51 · see citing works
Comparison of Open Appendectomy and Laparoscopic Appendectomy in Perforated Appendicitis
Nazir, A., Farooqi, S. A., Chaudhary, N. A., Bhatti, H. W., Waqar, M., & Sadiq, A. (2019) · Cureus · doi:10.7759/cureus.5105 · Cited by 51 · see citing works
Mabrouk, M., Raimondo, D., Mastronardi, M., Raimondo, I., Del Forno, S., Arena, A., Sutherland, N., Borgia, A., Mattioli, G., Terzano, P., et al. (2020) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2019.02.015 · Cited by 49 · see citing works
Risk factors for appendiceal neoplasm and malignancy among patients with acute appendicitis
Brunner, M., Lapins, P., Langheinrich, M. C., Baecker, J., Krautz, C., Kersting, S., Weber, G. F., Grützmann, R., & Maak, M. (2019) · International Journal of Colorectal Disease · doi:10.1007/s00384-019-03453-5 · Cited by 48 · see citing works
How good are surgeons at identifying appendicitis? Results from a multi-centre cohort study
Strong, S., Blencowe, N., & Bhangu, A. A. (2015) · International Journal of Surgery · doi:10.1016/j.ijsu.2015.01.032 · Cited by 46 · see citing works
Roberts, J. K., Behravesh, M., & Dmitrewski, J. (2008) · International Journal of Surgical Pathology · doi:10.1177/1066896908315746 · Cited by 46 · see citing works
Brockman, S., Scott, S., Guest, G. D., Stupart, D. A., Ryan, S., & Watters, D. A. (2013) · ANZ Journal of Surgery · doi:10.1111/ans.12211 · Cited by 44 · see citing works
Ilves, I., Paajanen, H., Herzig, K., Fagerström, A., & Miettinen, P. J. R. (2011) · World Journal of Surgery · doi:10.1007/s00268-011-0988-8 · Cited by 43 · see citing works
Saar, S., Talving, P., Laos, J., Põdramägi, T., Sokirjanski, M., Lustenberger, T., Lam, L., & Lepner, U. (2016) · World Journal of Surgery · doi:10.1007/s00268-016-3416-2 · Cited by 43 · see citing works
Clinicopathological Features and Management of Appendiceal Mucoceles: A Systematic Review
Morano, W. F., Gleeson, E., Sullivan, S. H., Padmanaban, V., Mapow, B. L., Shewokis, P. A., Esquivel, J., & Bowne, W. B. (2018) · The American Surgeon · doi:10.1177/000313481808400237 · Cited by 41 · see citing works
Saleem, A., Navarro, P. A., Munson, J. L., & Hall, J. F. (2010) · International Journal of Surgery Case Reports · doi:10.1016/j.ijscr.2010.11.001 · Cited by 41 · see citing works
Histopathologic analysis of appendectomy specimens
Shrestha, R., Ranabhat, S., & Tiwari, M. (1970) · Journal of Pathology of Nepal · doi:10.3126/jpn.v2i3.6025 · Cited by 37 · see citing works
Pathology of Gastrointestinal Disorders
Rindi, G., Inzani, F. S., & Solcia, E. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.08.009 · Cited by 36 · see citing works
Diagnosis and Treatment of Mucinous Appendiceal Neoplasm Presented as Acute Appendicitis
Kehagias, I., Zygomalas, A., Markopoulos, G., Papandreou, T., & Kraniotis, P. (2016) · Case Reports in Oncological Medicine · doi:10.1155/2016/2161952 · Cited by 35 · see citing works
One year negative appendicectomy rates at a district general hospital: A Retrospective Cohort Study
Lim, J., Pang, Q., & Alexander, R. J. (2016) · International Journal of Surgery · doi:10.1016/j.ijsu.2016.05.030 · Cited by 34 · see citing works
Khan, M. R., Ahmed, R., & Saleem, T. (2010) · Journal of Medical Case Reports · doi:10.1186/1752-1947-4-129 · Cited by 33 · see citing works
The Investigation of 14 Appendiceal Mucocele Cases Encountered in 4850 Appendectomy Patients
Şentürk, M., Yavuz, Y., Alkan, S., & Kafadar, M. T. (2020) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-020-00462-4 · Cited by 32 · see citing works
The Unacceptable Morbidity of Negative Laparoscopic Appendicectomy
Allaway, M. G. R., Eslick, G. D., & Cox, M. R. (2018) · World Journal of Surgery · doi:10.1007/s00268-018-4784-6 · Cited by 32 · see citing works
Liu, L., Shao, Z., Yu, H. J., Zhang, W., Wang, H., & Mei, Z. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233470 · Cited by 32 · see citing works
Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China
Zhou, Y., & Cen, L.-S. (2020) · World Journal of Clinical Cases · doi:10.12998/wjcc.v8.i19.4349 · Cited by 30 · see citing works
Georgiou, G. K., Bali, C. D., Theodorou, S. J., Zioga, A., & Fatouros, M. (2011) · Hernia · doi:10.1007/s10029-011-0822-0 · Cited by 29 · see citing works
Hussain, A., Mahmood, H., Singhal, T., Balakrishnan, S., & El‐Hasani, S. (2009) · PubMed · Cited by 29 · see citing works
Carcinoid Tumors of the Appendix: Are These Tumors Identifiable Prospectively on Preoperative CT?
Coursey, C. A., Nelson, R. C., Moreno, R. D., Dodd, L. G., Patel, M. B., & Vaslef, S. N. (2010) · The American Surgeon · doi:10.1177/000313481007600306 · Cited by 29 · see citing works
Xu, H., Yang, S., Xing, J., Wang, Y., Sun, W., Rong, L., & liu, H. (2023) · BMC Surgery · doi:10.1186/s12893-023-02108-1 · Cited by 28 · see citing works
Slotboom, T., Hamminga, J. T. H., Hofker, H. S., Heineman, E., Haveman, J.-W., & For the Apple Study Group; Appendicitis and Laparoscopic evaluation (2014) · Scandinavian Journal of Surgery · doi:10.1177/1457496913519771 · Cited by 28 · see citing works
Laparoscopic right hemicolectomy for mucocele due to a low-grade appendiceal mucinous neoplasm.
Palanivelu, C., Rangarajan, M., John, S. J., Senthilkumar, K., & Annapoorni, S. (2008) · PubMed Central · Cited by 27 · see citing works
Hamminga, J. T. H., Hofker, H. S., Broens, P. M. A., Kluin, P. M., Heineman, E., & Haveman, J. W. (2012) · Surgical Endoscopy · doi:10.1007/s00464-012-2634-4 · Cited by 27 · see citing works
Autophagy Suppression by Appendicitis and Appendectomy Protects Against Colitis
Cheluvappa, R., Luo, A. S., & Grimm, M. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000034 · Cited by 27 · see citing works
Histopathological examination of appendicectomy specimens at a district hospital of Saudi Arabia
Jat, M. A., Alswailmi, F. K., Mehmood, Y., Alrowaili, M., & Alanazi, S. (2015) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.314.7453 · Cited by 27 · see citing works
Surgical treatment of mucocele of the appendix: a systematic review and case report
Saad, E., Elsamani, E. Y., Abdelrahim, W. E., Elsiddig, K. E., & Khalil, E. A. G. (2018) · Journal of Surgical Case Reports · doi:10.1093/jscr/rjy102 · Cited by 27 · see citing works
The Incidence of Benign and Malignant Neoplasia Presenting as Acute Appendicitis
Sieren, L. M., Collins, J. N., Weireter, L. J., Britt, R. C., Reed, S. F., Novosel, T. J., & Britt, L. D. (2010) · The American Surgeon · doi:10.1177/000313481007600822 · Cited by 26 · see citing works
Goblet cell carcinoid neoplasm of the appendix: Clinical and CT features
Lee, K. S., Tang, L. H., Shia, J., Paty, P. B., Weiser, M. R., Guillem, J. G., Temple, L. K. F., Nash, G. M., Reidy, D., Saltz, L. B., et al. (2012) · European Journal of Radiology · doi:10.1016/j.ejrad.2012.05.038 · Cited by 26 · see citing works
Histopathological correlations of appendectomies: a clinical audit of a single center.
Omiyale, A. O., & Adjepong, S. (2015) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2305-5839.2015.05.02 · Cited by 25 · see citing works
T helper type 17 pathway suppression by appendicitis and appendectomy protects against colitis
Cheluvappa, R., Luo, A. S., & Grimm, M. (2013) · Clinical & Experimental Immunology · doi:10.1111/cei.12237 · Cited by 25 · see citing works
Puig, S., Staudenherz, A., Felder-Puig, R., & Paya, K. (2007) · Seminars in Roentgenology · doi:10.1053/j.ro.2007.08.004 · Cited by 25 · see citing works
Teixeira, P. G., & Δημητριάδης, Δ. (2013) · Advances in Surgery · doi:10.1016/j.yasu.2013.02.002 · Cited by 23 · see citing works
Laparoscopic accuracy in prediction of appendiceal pathology: oncologic and inflammatory aspects
Sadot, E., Keidar, A., Shapiro, R., & Wasserberg, N. (2013) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2013.05.002 · Cited by 23 · see citing works
Howell, E. C., Keeley, J. A., Kaji, A. H., Deane, M. R., Kim, D. Y., Putnam, B. A., Lee, S. L., Woods, A. L., & Neville, A. L. (2019) · Trauma Surgery & Acute Care Open · doi:10.1136/tsaco-2018-000264 · Cited by 21 · see citing works
Carcinoid Tumors in Children and Adolescents
Fernández, K. S., Aldrink, J. H., Ranalli, M. A., Ruymann, F. B., & Caniano, D. A. (2014) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0000000000000280 · Cited by 21 · see citing works
Acute appendicitis in South Africa: a systematic review.
Yang, E., Kahn, D. R., & Cook, C. (2015) · PubMed · Cited by 20 · see citing works
Cheluvappa, R. (2014) · International Journal of Colorectal Disease · doi:10.1007/s00384-014-1936-5 · Cited by 19 · see citing works
Cheluvappa, R. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy332 · Cited by 19 · see citing works
Bickel, A., Ganam, S., Shakra, I. A., Farkash, I., Francis, R., Karra, N., Merei, F., Cohen, I., & Kakiashvili, E. (2022) · BMC Gastroenterology · doi:10.1186/s12876-021-02024-9 · Cited by 19 · see citing works
Bolmers, M. D. M., de Jonge, J., van Rossem, C. C., van Geloven, A. A. W., Bemelman, W. A., Van Acker, G. J., Akkermans, B., Akkersdijk, G. J., Algie, G. D., Allema, J. H., et al. (2020) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-019-04345-3 · Cited by 18 · see citing works
Ingested Foreign Bodies Can Cause Appendicitis and Perforation: A Multi-Institutional Case Series
Fuller, M. Y., Leino, D. G., Reyes‐Múgica, M., Kovach, A. E., Vega, J. E. V., Caltharp, S. A., Bhatti, T. R., & González, R. S. (2022) · Pediatric and Developmental Pathology · doi:10.1177/10935266221083188 · Cited by 18 · see citing works
Protective pathways against colitis mediated by appendicitis and appendectomy
Cheluvappa, R., Luo, A. S., Palmer, C. S., & Grimm, M. (2011) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2011.04434.x · Cited by 18 · see citing works
Tartaglia, D., Bertolucci, A., Galatioto, C., Palmeri, M., Franco, G. D., Fantacci, R., Furbetta, N., & Chiarugi, M. (2016) · International Journal of Surgery · doi:10.1016/j.ijsu.2016.02.085 · Cited by 18 · see citing works
Rainer, T. H., Leung, L. Y., Chan, C. P.-Y., Leung, Y., Cheng, N., Lai, P., Cheung, Y. S., & Graham, C. A. (2017) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2017.02.010 · Cited by 18 · see citing works
Nationwide overview of survival and management of appendiceal tumors in children
Parikh, P. P., Perez, E. A., Neville, H. L., Hogan, A. R., & Sola, J. E. (2018) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2018.02.080 · Cited by 18 · see citing works
Practice of surgeons regarding examination of pathological specimens in operating room.
Haq, R. N. U., Khan, B. A., & Chaudhry, I. A. (2009) · PubMed · Cited by 17 · see citing works
Istl, A. C., Gage, M. M., Esquivel, J., Ahuja, N., Greer, J. B., & Johnston, F. M. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-020-09312-w · Cited by 17 · see citing works
Liang, T., Liu, S., Tsai, C., Kang, C., Huang, W., Chang, H., & Chen, I.-S. (2016) · Medicine · doi:10.1097/md.0000000000003159 · Cited by 17 · see citing works
Allaway, M. G. R., Eslick, G. D., Kwok, G., & Cox, M. R. (2017) · International Journal of Surgery · doi:10.1016/j.ijsu.2017.05.045 · Cited by 17 · see citing works
Goulart, R. N., Silvério, G. D. S., Moreira, M. B., & Franzon, O. (2012) · ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) · doi:10.1590/s0102-67202012000200005 · Cited by 17 · see citing works
Case of an appendiceal mucinous adenocarcinoma presenting as a left adnexal mass
Hajiran, A. J., Baker, K., Jain, P. R., & Hashmi, M. (2014) · International Journal of Surgery Case Reports · doi:10.1016/j.ijscr.2013.12.008 · Cited by 16 · see citing works
Damjanov, I., Vranić, S., & Skenderi, F. (2015) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-015-1801-0 · Cited by 16 · see citing works
Unexpected finding of laparoscopic appendectomy: appendix MALT lymphoma in children
Marte, A., Sabatino, M. D., CAUTIERO, P., Accardo, M., Romano, M., & Parmeggiani, P. (2007) · Pediatric Surgery International · doi:10.1007/s00383-007-1957-z · Cited by 16 · see citing works
Sørensen, A. K., Bang-Nielsen, A., Levic-Souzani, K., Pommergaard, H., Jørgensen, A. B., Tolstrup, M., Rud, B., Kovacevic, B., & Bulut, O. (2019) · International Journal of Surgery · doi:10.1016/j.ijsu.2019.02.001 · Cited by 16 · see citing works
Foreign body causing perforation of the appendix in an African boy
Hulme, P. (2010) · Pan African Medical Journal · doi:10.4314/pamj.v5i1.56193 · Cited by 15 · see citing works
Elfaedy, O., Benkhadoura, M., Elshaikhy, A. I., & Elgazwi, K. (2019) · Turkish Journal of Surgery · doi:10.5578/turkjsurg.4253 · Cited by 15 · see citing works
Review of the Pathologic Diagnoses of Appendectomy Specimens
Zulfikar, I., Khanzada, T. W., Sushel, C., & Samad, A. R. (2009) · Annals of King Edward Medical University · doi:10.21649/akemu.v15i4.61 · Cited by 15 · see citing works
Tran, N., Emuakhagbon, V.-S., Baker, B. T., & Huerta, S. (2020) · Journal of Surgical Case Reports · doi:10.1093/jscr/rjaa543 · Cited by 14 · see citing works
Can d-dimer become a new diagnostic parameter for acute appendicitis?
Menteş, Ö., Eryılmaz, M., Harlak, A., Özer, T., Balkan, M., Kozak, O., & Tufan, T. (2009) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2008.06.001 · Cited by 14 · see citing works
Collision tumor of the appendix: mucinous cystadenoma and carcinoid. A case report.
Dellaportas, D., Vlahos, N., Polymeneas, G., Gkiokas, G., Dastamani, C., Carvounis, E. E., & Theodosopoulos, T. (2014) · PubMed · Cited by 14 · see citing works
Four mucinous cystadenoma of the appendix treated by different approaches
Kilic, M. O., İnan, A., & Bozer, M. (2014) · Turkish Journal of Surgery · doi:10.5152/ucd.2014.2397 · Cited by 14 · see citing works
Dohner, E., Kierdorf, F. J., Langer, R., Zuber, M., & Fahrner, R. (2024) · BMC Surgery · doi:10.1186/s12893-024-02412-4 · Cited by 13 · see citing works
Zarandi, N. P., Parsijani, P. J., Bolandparvaz, S., Paydar, S., & Abbasi, H. (2014) · Europe PMC (PubMed Central) · Cited by 13 · see citing works
Cheluvappa, R., Eri, R. D., Luo, A. S., & Grimm, M. (2014) · International Journal of Colorectal Disease · doi:10.1007/s00384-014-1974-z · Cited by 13 · see citing works
Appendiceal Mucocele in an Elderly Patient: How Much Surgery?
Kim-Fuchs, C., Kuruvilla, Y. C. K., Angst, E., Weimann, R., Gloor, B., & Candinas, D. (2011) · Case Reports in Gastroenterology · doi:10.1159/000331438 · Cited by 13 · see citing works
Clinicopathologic findings in gynecologic proliferations of the appendix
Noor, M., Chen, A., & González, R. S. (2019) · Human Pathology · doi:10.1016/j.humpath.2019.08.004 · Cited by 13 · see citing works
Large mucinous neoplasm of the appendix mimicking adnexal mass in a postmenopausal woman
Akman, L., Hurşitoğlu, B. S., Hortu, İ., Sezer, T. Ö., Öztekin, K., & Avsargil, B. D. (2014) · International Journal of Surgery Case Reports · doi:10.1016/j.ijscr.2014.11.050 · Cited by 13 · see citing works
Kinnear, N., Heijkoop, B., Bramwell, E., Frazzetto, A., Noll, A., Patel, P., Hennessey, D., Otto, G., Dobbins, C., Sammour, T., et al. (2019) · International Journal of Surgery · doi:10.1016/j.ijsu.2019.10.025 · Cited by 12 · see citing works
Jedrzkiewicz, J., Tateishi, Y., Kirsch, R., Conner, J., Bischof, D. A., McCart, A., Riddell, R. H., Pollett, A. F., Taylor, E. L., & Govindarajan, A. (2019) · Archives of Pathology & Laboratory Medicine · doi:10.5858/arpa.2019-0214-oa · Cited by 12 · see citing works
Rassi, R., Muse, F., Sánchez-Martínez, J., & Cuestas, E. (2021) · European Journal of Pediatric Surgery · doi:10.1055/s-0041-1722860 · Cited by 12 · see citing works
- Authors
- Marudanayagam, R., Williams, G. T., & Rees, B. I.
- Affiliations
- University Hospital of Wales (GB)
- ORCID
- Marudanayagam, Ravi
- Venue
- Journal of Gastroenterology
- Published
- 2006-09-19
- Volume
- 41
- Issue
- 8
- Pages
- 745-749
- ISSN
- 0944-1174 (ISSN-L)
- 1435-5922
- OpenAlex
- W1966647446
- Cited by
- 291
- References
- 22
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 17 · 2023: 10 · 2022: 27 · 2021: 15 · 2020: 21 · 2019: 19 · 2018: 22 · 2017: 17 · 2016: 19 · 2015: 7 · 2014: 23 · 2013: 15 · 2012: 16
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Appendicitis Diagnosis and Management
- Health Sciences › Medicine › Surgery › Intraperitoneal and Appendiceal Malignancies
- Health Sciences › Medicine › Rheumatology › Omental and Epiploic Conditions
- Keywords
- appendicitis, appendectomy, pathological diagnosis, acute appendicitis, appendiceal perforation, appendiceal neoplasms, appendiceal carcinoid, appendiceal adenocarcinoma, mucinous cystadenoma, age-related incidence, seasonal variation, laparoscopic appendectomy
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Appendectomy, Appendicitis, Appendix, Child, Female, Humans, Male, Middle Aged, Laparoscopy, Retrospective Studies, Age Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
