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Gender and 5-years course of psychosis patients: focus on clinical and social variables
Abstract
Most studies on gender and psychosis have focused on gender differences at illness onset or on the long-term outcome, whereas little is known about the impact of gender on the first years after psychosis onset. A total of 185 first episode psychosis (FEP) patients were followed for 5 years after psychosis onset, and gender differences were explored in psychopathology (PANSS), needs for care (CAN), and insight (SAI-E). Male patients showed more negative symptoms than females over time, whereas female patients showed higher levels of depressive symptoms than males throughout the study period. In addition, female patients presented more functioning unmet needs for care, but higher levels of insight into illness than males. Therapy and rehabilitative programs for FEP patients should be gender-targeted, as gender has proved to impact on psychopathology, needs for care, and insight in the very first years following psychosis onset.
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Sex/gender differences are found in psychiatric comorbidities, with aggressive behavior and substance use disorder in men contrasting with eating disorders and depression in women.
“In some cases, sex/gender differences are found in the psychiatric comorbidities associated with a predominant mental disorder -e.g., aggressive behavior and substance use disorder in men, contrasting with eating disorders and depression in women (26–30).”
From Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness (2022) · cites this paper as [28]
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Sorted by citations
Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness
Christiansen, D. M., McCarthy, M. M., & Seeman, M. V. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.856436 · Cited by 65
Metadata
- Authors
- the PICOS Veneto Group, Comacchio, C., Lasalvia, A., Bonetto, C., Cristofalo, D., Miglietta, E., Petterlini, S., De Santi, K., Tosato, S., Riolo, R., Cremonese, C., Ceccato, E., Zanatta, G., & Ruggeri, M.
- Affiliations
- University of Verona (IT)
- Corresponding author
- Comacchio, Carla
- ORCID
- Venue
- Archives of Women's Mental Health
- Published
- 2019-02-04
- Volume
- 23
- Issue
- 1
- Pages
- 63-70
- ISSN
- 1434-1816 (ISSN-L)
- 1435-1102
- OpenAlex
- W2911915827
- Cited by
- 18
- References
- 1
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 1
- FWCI
- 1.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Archives of Women s Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System (Università degli Studi di Trento) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Keywords
- gender differences, first-episode psychosis, negative symptoms, depressive symptoms, insight into illness, long-term follow-up
- MeSH terms
- Adolescent, Adult, Demography, Female, Follow-Up Studies, Health Services Needs and Demand, Humans, Italy, Male, Mental Health Services, Middle Aged, Psychiatric Status Rating Scales, Psychotic Disorders, Sex Factors, Social Adjustment, Time Factors, Cohort Studies, Young Adult
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