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The clinical epicondylar axis is not the functional flexion axis of the human knee
Abstract
Background The functional flexion axis (FFA) is the principal axis around which the knee moves and thus, by definition, does not move in vertical displacement relative to the tibia. The transepicondylar axis (TEA) has been reported to coincide with the FFA. If that is not true, the TEA should show vertical displacement during motion, and this hypothesis was investigated. Methods Three-dimensional knee kinematics of 20 healthy volunteers were determined during a squatting motion via a 3-dimensional to 2-dimensional image registration technique by calculating the vertical displacement of the clinical epicondylar axis (CEA) through the full range of motion. Results From 0° to 90° knee flexion, the average vertical displacement of the lateral end of the CEA was <3 mm, whereas that of the medial end was large (7.6 mm). Discussion The large vertical displacement of the medial end of the CEA suggests that the CEA is not the FFA. This finding implies that the CEA may not be an appropriate axis for a TKA prosthesis having a "single radius" design. Evidence level Level IV.
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Knee-joint motions vary widely due to subject-specific differences, measurement approaches, and functional flexion axis (FFA) selection.
“knee265 joint motions vary widely due to subject-specific differences, measurement 266 approaches, and FFA selection ( e.g., [37, 38]).”
From Computational study of kinematics of the anterior cruciate ligament double-bundle structure during passive knee flexion-extension (2020) · cites this paper as [38]
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Otani, T., Kobayashi, Y., & Tanaka, M. (2020) · Medical Engineering & Physics · doi:10.1016/j.medengphy.2020.07.015 · Cited by 7
Metadata
- Authors
- Mochizuki, T., Sato, T., Watanabe, S., Koga, Y., Blaha, J. D., Tanifuji, O., Yamagiwa, H., Endo, N., Kobayashi, K., & Omori, G.
- Affiliations
- University of Michigan (US)
- Niigata Medical Center (JP)
- Niigata University (JP)
- Corresponding author
- Mochizuki, Tomoharu
- ORCID
- Venue
- Journal of Orthopaedic Science
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 19
- Issue
- 3
- Pages
- 451-456
- ISSN
- 0949-2658 (ISSN-L)
- OpenAlex
- W1990475800
- Cited by
- 34
- References
- 0
- Citations by year
- 2025: 2 · 2023: 3 · 2022: 2 · 2021: 8 · 2020: 3 · 2019: 4 · 2018: 5 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 1
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Orthopaedic Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Japan Society for the Promotion of Science (24246025)
- Topics
- Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
- Health Sciences › Medicine › Surgery › Total Knee Arthroplasty Outcomes
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Keywords
- transepicondylar axis, knee kinematics, squatting motion, vertical displacement, total knee arthroplasty
- MeSH terms
- Adult, Algorithms, Biomechanical Phenomena, Female, Humans, Knee Joint, Male, Middle Aged, Reference Values, Tomography, X-Ray Computed, Range of Motion, Articular, Imaging, Three-Dimensional
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