The DOI matches its Crossref record.
Dental and oral anomalies in incontinentia pigmenti: a systematic review
Abstract
Objectives Incontinentia pigmenti (IP) is an X-linked genodermatosis caused by a mutation of the IKBKG gene. The objective of this study was to present a systematic review of the dental and oral types of anomalies, to determine the total number and sex distribution of the anomalies, and to analyze possible therapies. Materials and methods We analyzed the literature data from 1,286 IP cases from the period 1993-2010. Results Dental and/or oral anomalies were diagnosed for 54.38% of the investigated IP patients. Most of the anomaly types were dental, and the most frequent of these were dental shape anomalies, hypodontia, and delayed dentition. The most frequent oral anomaly types were cleft palate and high arched palate. IKBKG exon 4-10 deletion was present in 86.36% of genetically confirmed IP patients. Conclusions According to the frequency, dental and/or oral anomalies represent the most frequent and important IP minor criteria. The most frequent mutation was IKBKG exon 4-10 deletion. The majority of dental anomalies and some of the oral anomalies could be corrected. Clinical relevance Because of the presence of cleft palate and high arched palate in IP patients, these two anomalies may be considered as diagnostic IP minor criteria as well.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Dental and oral anomalies like delayed dentition, pegged or conical teeth, anodontia or hypodontia, and cleft or high-arched palate occur in almost all patients with incontinentia pigmenti.
“Dental and oral anomalies like delayed dentition, pegged or conical teeth, anodontia or hypodontia, and cleft or high-arched palate occur in almost all patients.[32]”
From Ectodermal Dysplasia – An Overview and Update (2024) · cites this paper as [32]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 38
- Berlin A, Paller AS, Chan LS (2002) Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology. J Am Acad Dermatol 47:169–187. doi: 10.1067/mjd.2002.125949 · DOI
- Smahi A, Courtois G, Vabres P, Yamaoka S, Heuertz S, Munnich A, Israël A, Heiss NS, Klauck SM, Kioschis P, Wiemann S, Poustka A, Esposito T, Bardaro T, Gianfrancesco F, Ciccodicola A, D’Urso M, Woffendin H, Jakins T, Donnai D, Stewart H, Kenwrick SJ, Aradhya S, Yamagata T, Levy M, Lewis RA, Nelson DL (2000) Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature 405:466–472. doi: 10.1038/35013114 · DOI
- Courtois G, Gilmore TD (2006) Mutations in the NF-κB signaling pathway: implication for human disease. Oncogene 25:6831–6843. doi: 10.1038/sj.onc.1209939 · DOI
- Orange JS, Levy O, Geha RS (2005) Human disease resulting from gene mutations that interfere with appropriate nuclear factor-κB activation. Immunol Rev 203:21–37. doi: 10.1111/j.0105-2896.2005.00221.x · DOI
- Scheuerle A, Ursini MV. Incontinentia pigmenti (Bloch–Sulzberger syndrome). University of Washington, Seattle (WA): GeneReviews 2008 Feb, 22 pp. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=i-p . Accessed 28 Oct 2010
- Fusco F, Paciolla M, Napolitano F, Pescatore A, D’Addario I, Bal E, Lioi MB, Smahi A, Miano MG, Ursini MV (2012) Genomic architecture at the incontinentia pigmenti locus favours de novo pathological alleles through different mechanisms. Hum Mol Genet 1:1260–1271. doi: 10.1093/hmg/ddr556 · DOI
- Fusco F, Bardaro T, Fimiani G, Mercadante V, Miano MG, Falco G, Israël A, Courtois G, D’Urso M, Ursini MV (2004) Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-κB activation. Hum Mol Genet 13:1763–1773. doi: 10.1093/hmg/ddh192 · DOI
- Landy SJ, Donnai D (1993) Incontinentia pigmenti (Bloch–Sulzberger syndrome). J Med Genet 30:53–59 · DOI · Paper page
- Garcia-Dorado J, de Unamuno P, Fernandez-Lopez E, Salazar Veloz J, Armijo M (1990) Incontinentia pigmenti: XXY male with a family history. Clin Genet 38:128–138 · DOI
- Hadj-Rabia S, Rimella A, Smahi A, Fraitag S, Hamel-Teillac D, Bonnefont JP, de Prost Y, Bodemer C (2011) Clinical and histologic features of incontinentia pigmenti in adults with nuclear factor-κB essential modulator gene mutations. J Am Acad Dermatol 64:508–515. doi: 10.1016/j.jaad.2010.01.045 · DOI · Paper page
- Garrod AE (1906) Peculiar pigmentation of the skin of an infant. Trans Clin Soc London 39:216
- Carney RG (1976) Incontinentia pigmenti: a world statistical analysis. Arch Dermatol 112:535–542 · DOI
- Parrish JE, Scheuerle AE, Lewis RA, Levy ML, Nelson DL (1996) Selection against mutant alleles in blood leukocytes is a consistent feature in incontinentia pigmenti type 2. Hum Mol Genet 5:1777–1783. doi: 10.1093/hmg/5.11.1777 · DOI
- Minić S, Novotny GEK, Trpinac D, Obradović M (2006) Clinical features of incontinentia pigmenti with emphasis on oral and dental abnormalities. Clin Oral Invest 10:343–347. doi: 10.1007/s00784-006-0066-z · DOI
- Phan TA, Wargon O, Turner AM (2005) Incontinentia pigmenti case series: clinical spectrum of incontinentia pigmenti in 53 female patients and their relatives. Clin Exp Dermatol 30:474–480. doi: 10.1111/j.1365-2230.2005.01848.x · DOI
- Holmström G, Bergendal B, Hallberg G, Marcus S, Hallén A, Dahl N (2002) Incontinentia pigmenti—a rare disease with many symptoms. Lakartidningen 99:1345–1350
- Hadj-Rabia S, Froidevaux D, Bodak N, Hamel-Teillac D, Smahi A, Touil Y, Fraitag S, de Prost Y, Bodemer C (2003) Clinical study of 40 cases of incontinentia pigmenti. Arch Dermatol 139:1163–1170 · DOI
- Sachs L (1984) Applied statistics, 2nd edn. Springer, New York · DOI
- Mansour S, Woffendin H, Mitton S, Jeffery I, Jakins T, Kenwrick S, Murday VA (2001) Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection. Am J Med Genet 99:172–177. doi:10.1002/1096-8628(2001) 9999:9999<::AID-AJMG1155>3.0.CO;2-Y · DOI
- Dupuis-Girod S, Corradini N, Hadj-Rabia S, Fournet JC, Faivre L, Le Deist F, Durand P, Döffinger R, Smahi A, Israël A, Courtois G, Brousse N, Blanche S, Munnich A, Fischer A, Casanova JL, Bodemer C (2002) Osteopetrosis, lymphedema, anhidrotic ectodermal dysplasia, and immunodeficiency in a boy and incontinentia pigmenti in his mother. Pediatrics 109:e97. doi: 10.1542/peds.109.6.e97 · DOI
- Rola M, Martins T, Melo MJ, Gomes R, Roseira J, Souto A (2004) Incontinence of pigment. An Pediatr (Barc) 60:601–602 · DOI
- Zou CC, Zhao ZY (2007) Clinical and molecular analysis of NF-κB essential modulator in Chinese incontinentia pigmenti patients. Int J Dermatol 46:1017–1022. doi: 10.1111/j.1365-4632.2007.03365.x · DOI
- Yonezu T, Hayashi Y, Sasaki J, Machida Y (1997) Prevalence of congenital dental anomalies of the deciduous dentition in Japanese children. Bull Tokyo Dent Coll 38:27–32
- Polder BJ, Van’t Hof MA, Van der Linden FPGM, Kuijpers-Jagtman AM (2004) A meta-analysis of the prevalence of dental agenesis of permanent teeth. Community Dent Oral Epidemiol 32:217–226. doi: 10.1111/j.1600-0528.2004.00158.x · DOI
- Himelhoch DA, Scott BJ, Olsen RA (1987) Dental defects in incontinentia pigmenti: case report. Pediatr Dent 9:236–239
- Macey-Dare LV, Goodman JR (1999) Incontinentia pigmenti: seven cases with dental manifestations. Int J Paediatr Dent 9:293–297 · DOI
- Bentolila R, Rivera H, Sanchez-Quevedo MC (2006) Incontinentia pigmenti: a case report. Pediatr Dent 28:54–57
- Psoter WJ, Zhang H, Pendrys DG, Morse DE, Mayne ST (2003) Classification of dental caries patterns in the primary dentition: a multidimensional scaling analysis. Community Dent Oral Epidemiol 31:231–238. doi: 10.1034/j.1600-0528.2003.00044.x · DOI
- Wang X, Shaffer JR, Weyant RJ, Cuenco KT, DeSensi RS, Crout R, McNeil DW, Marazita ML (2010) Genes and their effects on dental caries may differ between primary and permanent dentitions. Caries Res 44:277–284. doi: 10.1159/000314676 · DOI
- Kurczynski TW, Berns JS, Johnson WE (1982) Studies of a family with incontinentia pigmenti variably expressed in both sexes. J Med Genet 19:447–451 · DOI
- Mossey PA, Little J, Munger RG, Dixon MJ, Shaw WC (2009) Cleft lip and palate. Lancet 374:1773–1785. doi: 10.1016/S0140-6736(09)60695-4 · DOI
- Minić S, Obradović M, Kovačević I, Trpinac D (2010) Ocular anomalies in Incontinentia pigmenti—literature review and meta-analysis. Srp Arh Celok Lek 138:408–413. doi: 10.2298/SARH1008408M · DOI
- Thesleff I (2006) The genetic basis of tooth development and dental defects. Am J Med Genet A 140A:2530–2535. doi: 10.1002/ajmg.a.31360 · DOI
- Kouskoura T, Fragou N, Alexiou M, John N, Sommer L, Graf D, Katsaros C, Mitsiadis TA (2011) The genetic basis of craniofacial and dental abnormalities. Schweiz Monatsschr Zahnmed 121:636–646
- Jacobsen P (2008) Restorative dentistry. An integrative approach, 2nd edn. Wiley-Blackwell, Oxford
- Jensen JL, Album B (2011) Tooth transplantation in cherubism and incontinentia pigmenti: report of two unusual cases. Oral Surg 4:39–43. doi: 10.1111/j.1752-248X.2010.01105.x · DOI
- Ciminello FS, Morin RJ, Nguyen TJ, Wolfe SA (2009) Cleft lip and palate: review. Compr Ther 35:37–43
- Martinez-Pomar N, Munoz-Saa I, Heine-Suner D, Martin A, Smahi A, Matamoros N (2005) A new mutation in exon 7 of NEMO gene: late skewed X-chromosome inactivation in an incontinentia pigmenti female patient with immunodeficiency. Hum Genet 118:458–465. doi: 10.1007/s00439-005-0068-y · DOI
Cited by
Sorted by citations
Incontinentia pigmenti diagnostic criteria update
Minić, S., Trpinac, D., & Obradović, M. (2014) · Clinical Genetics · doi:10.1111/cge.12223 · Cited by 164
“To obtain consistent and comparable data on the frequency of hair and ocular anomalies in the IP literature for the period 1993–2012, we carried out the meta-analysis of these anomalies in a manner similar to that used in systematic reviews of central nervous system (CNS), dental, and oral anomalies (4, 7).”
BackgroundMethodInfluentialSelf-citationKubala, E., Strzelecka, P. M., Grzegocka, M., Lietz–Kijak, D., Gronwald, H., Skomro, P., & Kijak, E. (2018) · BioMed Research International · doi:10.1155/2018/6572381 · Cited by 152
Incontinentia pigmenti (Bloch-Sulzberger syndrome).
Narayanan, M., Rangasamy, S., & Narayanan, V. (2015) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-62702-5.00020-2 · Cited by 108
Systematic review of central nervous system anomalies in incontinentia pigmenti
Minić, S., Trpinac, D., & Obradović, M. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-25 · Cited by 111
“38% (279/513) of the investigated IP patients [43].”
Self-citationIncontinentia Pigmenti: A Comprehensive Review and Update.
Swinney, C., Han, D. P., & Karth, P. (2015) · Ophthalmic Surgery Lasers and Imaging Retina · doi:10.3928/23258160-20150610-09 · Cited by 85
Mosaic Neurocutaneous Disorders and Their Causes
Ruggieri, M., & Praticò, A. D. (2015) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2015.11.001 · Cited by 92
The epidemiology of supernumerary teeth and the associated molecular mechanism
Lu, X., Yu, F., Liu, J.-J., Cai, W.-P., Zhao, Y., Zhao, S.-L., & Liu, S.-F. (2017) · Organogenesis · doi:10.1080/15476278.2017.1332554 · Cited by 80
“[85] Mini c S, Trpinac D, Gabriel H, Gencik M, Obradovi c M.”
BackgroundOrodental manifestations in ectodermal dysplasia—A review
Bergendal, B. (2014) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36571 · Cited by 71
“A recent systematic review on oral anomalies in IP used data from the literature published 1993 to 2010 and reported oral anomalies in 54.4% in 513 cases of IP [Minic et al., 2013].”
InfluentialBodemer, C., Diociaiuti, A., Hadj‐Rabia, S., Robert, M. P., Desguerre, I., Manière, M. ‐., de la Dure‐Molla, M., De Liso, P., Federici, M., Galeotti, A., et al. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.16403 · Cited by 59
“12 31 – 33 Dental anomalies are constant in IP, and careful tooth investigation is mandatory.”
BackgroundOptimization of pH and dispersant amount of Y-TZP suspension for colloidal stability
Chin, C., Muchtar, A., Azhari, C., Razali, M., & Aboras, M. (2015) · doi:10.1016/j.ceramint.2015.04.073 · Cited by 35
Unraveling incontinentia pigmenti: A comparison of phenotype and genotype variants.
Wang, R., Lara-Corrales, I., Kannu, P., & Pope, E. (2019) · Journal of American Academy of Dermatology · doi:10.1093/pch/pxy054.083 · Cited by 22
Color stability of mineral trioxide aggregate and calcium enriched mixture cement.
Eghbal, M., Torabzadeh, H., Bagheban, A. A., Shamszadeh, S., Marvasti, L., & Asgary, S. (2016) · Journal of Investigative and Clinical Dentistry · doi:10.1111/jicd.12164 · Cited by 19
Pengelly, R. J., Upstill‐Goddard, R., Arias, L., Martínez, J., Gibson, J., Knut, M., Collins, A., Ennis, S., Collins, A., & Briceno, I. (2014) · Clinical Genetics · doi:10.1111/cge.12547 · Cited by 19
Ectodermal Dysplasia – An Overview and Update
Dev, A., Malhi, K., & Mahajan, R. (2024) · Indian Dermatology Online Journal · doi:10.4103/idoj.idoj_599_23 · Cited by 19
“[32] è Breast and nipple hypoplasia and aplasia, supernumerary nipples can occur. è Ocular anomalies like proliferative retinopathy, [33] microaneurysms, macular occlusive disease, non‑perfusion, and rarely microphthalmia. è Neurologic symptoms include lethargy, poor feeding, seizures,…”
BackgroundGru, A. A., & Salavaggione, A. L. (2017) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2017.02.002 · Cited by 16
Avascular Peripheral Retina in Infants
Özdek, Ş., Zeydanlı, E. Ö., Baumal, C., Hoyek, S., Patel, N. A., Berrocal, A., López-Cañizares, A., Al-khersan, H., Kusaka, S., Mano, F., et al. (2023) · Turkish journal of ophthalmology · doi:10.4274/tjo.galenos.2022.76436 · Cited by 15
Incontinentia pigmenti and the eye
Islam, Y. F. K., & Khurshid, S. G. (2022) · Current Opinion in Ophthalmology · doi:10.1097/icu.0000000000000863 · Cited by 19
“shape, delayed dental eruption, and hypodontia [4].”
BackgroundChen, A., & Chen, K. (2017) · European Journal of Dentistry · doi:10.4103/ejd.ejd_95_17 · Cited by 14
“2% that was much higher than the prevalence in different ethnic groups, both males and females.[4] In the maxillary arch, the most common missing teeth were the lateral incisors followed by the second premolars”
BackgroundInfluentialHuman Genetic Diseases Linked to the Absence of NEMO: An Obligatory Somatic Mosaic Disorder in Male
Pescatore, A., Spinosa, E., Casale, C., Lioi, M. B., Ursini, M. V., & Fusco, F. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031179 · Cited by 11
“Clinical phenotype includes: ophthalmologic defects present in 36–30% of IP female (reviewed in a meta-analysis by [28] and reported by [11] in the largest case report, respectively) such as: retinal detachments, retinal vascular anomalies, cataracts and strabismus/vision defect, microphthalmia, optic nerve atrophy; o…”
BackgroundSun, S., Li, F., Liu, Y., Qu, H., Wong, S., Zeng, L., Yu, M., Feng, H., Liu, H.-C., & Han, D. (2019) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2019.03.013 · Cited by 10
Dental anomalies in 14 patients with IP: clinical and radiological analysis and review
Santa-Maria, F. D., Mariath, L. M., Poziomczyk, C. S., Maahs, M., Rosa, R., Zen, P. R. G., Schüller-Faccini, L., & Kiszewski, A. E. (2016) · Clinical Oral Investigations · doi:10.1007/s00784-016-1977-y · Cited by 10
Incontinentia Pigmenti: A Case Report of a Complex Systemic Disease
Gianfaldoni, S., Tchernev, G., Wollina, U., & Lotti, T. (2017) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2017.128 · Cited by 9
“delayed dentition, partial anodontia, hypodontia, abnormally shaped teeth) are the most commonly reported, occurring in more than 80% of all patients [16,17].”
BackgroundMorandini, A. C., Adeogun, O., Black, M., Holman, E., Collins, K., James, W., Lally, L., Fordyce, A., Dobbs, R., McDaniel, E., et al. (2025) · Frontiers in Pediatrics · doi:10.3389/fped.2025.1523313 · Cited by 7
“IKBKG activates NF-κ B, and its highest level of expression is in the CNS, which suggests why seizures are common in patients with incontinentia pigmenti (53, 54).”
Rosser, T. (2024) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2024.101156 · Cited by 6
Intrafamilial clinical variability in four families with incontinentia pigmenti
Mariath, L. M., Santa-Maria, F. D., Poziomczyk, C. S., Travi, G. M., Wachholz, G., de Souza, S. R., Kiszewski, A. E., & Schuler-Faccini, L. (2018) · American Journal of Medical Genetics. Part A · doi:10.1002/ajmg.a.40497 · Cited by 6
“phenotypic expression, encompassing skin, teeth, and other neuroectodermal defects (Minić et al., 2013).”
BackgroundMinić, S., Cerovac, N., Novaković, I. V., Gazikalović, S., Popadić, S., & Trpinac, D. (2023) · Diagnostics · doi:10.3390/diagnostics13071300 · Cited by 6
Self-citationReliability and Accuracy of Digital Impression Obtained from CS-3500 Intraoral Scanner
Kim, S.-H., Kim, J., & Kim, C.-K. (2015) · Journal of dental hygiene science · doi:10.17135/jdhs.2015.15.5.673 · Cited by 5
Blaschko line analogies in the central nervous system: a hypothesis.
Minić, S., Trpinac, D., & Obradović, M. (2013) · Medical Hypotheses · doi:10.1016/j.mehy.2013.07.024 · Cited by 5
Self-citationFirst IKBKG gene mutation study in Serbian incontinentia pigmenti patients.
Minić, S., Trpinac, D., Gabriel, H., Genčík, M., & Obradović, M. (2013) · Srpski Arhiv za Celokupno Lekarstvo · doi:10.2298/sarh1308490m · Cited by 3
“38% of IP patients and comprise dental shape anomalies, hypodontia, and delayed dentition [9].”
BackgroundSelf-citationOrthodontic Treatment for Bloch-Sulzberger Syndrome in Patient with Cleft Lip and Palate.
Nojima, K., Onoda, M., Nishii, Y., & Sueishi, K. (2017) · The Bulletin of Tokyo Dental College · doi:10.2209/tdcpublication.2016-0051 · Cited by 3
NEMO Gene Mutations in Two Chinese Females with Incontinentia Pigmenti
Jiang, J., Zeng, J., He, Q., Yang, J., Wang, S., & Zhang, Z.-Z. (2022) · Clinical, Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s363683 · Cited by 2
“This phenomenon might be a result of X-chromosome inactivation.(15) Although the classic phenotype is most common in females, sometimes 46, XY males present an IP phenotype.”
BackgroundSanta-Maria, F. D., Barros, S. E., Chiqueto, K., Mariath, L. M., Schuler-faccini, L., & Kiszewski, A. E. (2021) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2020.03.033 · Cited by 2
Incontinentia pigmenti: A case report and literature review
Puranik, C., & Redford-Badwal, D. (2017) · doi:10.4103/jpd.jpd_48_17 · Cited by 2
“[4,8] History of multiple male miscarriages, histopathologic features of IP, IKBKG mutation, and family history of similar condition could be used as additional criteria for IP diagnosis.”
BackgroundIncontinentia pigmenti with neurologic and oculodental disorders
Fierro, J., & Aviña, D. H. H. (2016) · doi:10.4103/2319-7250.173154 · Cited by 2
“[9] The dental abnormalities are hypodontia and partial anodontia, delayed eruption and the presence of dental teeth in peg’s deformation or conical‐shaped teeth.[10] There is no treatment for this generalized disorder, and the multisystem manifestations of the disease require that the management of the patient must b…”
BackgroundCase report: Variability in clinical manifestations within a family with incontinentia pigmenti
Belysheva, T., Nasedkina, T., Kletskaya, I., Volchek, D., Barinova, I., Semenova, V., Gadzhigoroeva, A., Zelenova, E., Valiev, T., Sharapova, E., et al. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1402577 · Cited by 1
Ergin, F., Tekin, M., Güneş, M., Güneş, B., Baysun, Ş., & Akar, N. (2022) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-022-00215-x · Cited by 1
A Report of Incontinentia Pigmenti in an 11-year-old Girl
Azarbayjani, Z., Enshaei, Z., & Eshghi, A. (2021) · doi:10.5812/ijp.103348 · Cited by 1
Otsuka, Y., & Suda, N. (2017) · doi:10.1016/j.odw.2017.09.006 · Cited by 1
“Dental abnormalities such as hypodontia, tooth shape anomalies (cone- or peg-shaped teeth), and delayed tooth eruption are associated with IP [4,5].”
BackgroundDental findings and management in a child with hypomelanosis of Ito
Hasegawa, T., Akazawa, Y., Kitamura, T., Sugimoto, A., Ueda, K., & Iwamoto, T. (2014) · doi:10.1016/j.pdj.2014.08.002 · Cited by 1
Sartori‐Valinotti, J. C., & Hand, J. L. (2019) · Springer eBooks · doi:10.1007/978-3-030-10863-2_11 · Cited by 1
Kiray, G., de Souza, C. D., Kalitzeos, A., Michaelides, M., & Wong, S.-C. (2026) · AJO International · doi:10.1016/j.ajoint.2026.100306
A case of Incontinentia Pigmenti associated with concurrent IKBKG/NEMO and MED13L mutations
Spinosa, E., Rosain, J., Picascia, S., Salvia, M., Pescatore, A., Torella, A., Piluso, G., Nigro, V., Piccolo, V., Diociaiuti, A., et al. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1819035
Incontinentia pigmenti: exploring the oral manifestations
Jain, Y., Ajıla, V., Babu, G., & Smrithy Sivadas, K. (2026) · BMJ Case Reports · doi:10.1136/bcr-2025-267478
Anaesthesia and orphan disease: A child with incontinentia pigmenti.
Sugur, T., Kavakli, A. S., & Metinyurt, H. F. (2020) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000001136
Raising the Self Esteem with the Oral Rehabilitation of a Child with Incontinentia Pigmenti Syndrome
Smhc, Á. D. A. (2017) · doi:10.26420/austinjdent.2017.1091
“Some of these anomalies may greatly influence the quality of life causing psychological and feeding problems [7].”
BackgroundPoliak, N., Le, A., & Rainey, A. (2016) · Case Reports in Pediatrics · doi:10.1155/2016/9512627
dos Reis, L. R., Diffini, F., Maria, S., Fabiano, R., Rosa, M., Schermann, C., Kiszewski, A. E., Goetze, T. B., Angélica, M., Maahs, P., et al. (2015) · doi:10.1590/s2317-64312015000100001502
“One advantage is that it is visible since birth, in contrast to dental anomalies that are detectable only after 1 year((16)).”
BackgroundInfluentialKieswetter, L., & Pope, E. (2022) · Neurocutaneous Disorders · doi:10.1007/978-3-030-87893-1_8
Biological Basis of Craniofacial Soft Tissue Malformations
Wermker, K. (2021) · Fundamentals of Craniofacial Malformations · doi:10.1007/978-3-030-46024-2_12
Metadata
- Authors
- Minić, S., Trpinac, D., Gabriel, H., Gencik, M., & Obradović, M.
- Affiliations
- University of Belgrade (RS)
- Corresponding author
- Minić, Snežana
- Venue
- Clinical Oral Investigations
- Published
- 2012-03-28
- Volume
- 17
- Issue
- 1
- Pages
- 1-8
- ISSN
- 1432-6981 (ISSN-L)
- 1436-3771
- OpenAlex
- W2116728509
- Cited by
- 64
- References
- 0
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 9 · 2016: 4 · 2015: 9 · 2014: 6 · 2013: 4
- FWCI
- 0.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Clinical Oral Investigations (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Genetic and rare skin diseases.
- Health Sciences › Dentistry › General Dentistry › dental development and anomalies
- Health Sciences › Dentistry › Oral Surgery › Cleft Lip and Palate Research
- Keywords
- incontinentia pigmenti, dental anomalies, oral anomalies, genodermatosis, tooth agenesis, cleft palate, high-arched palate, sex distribution
- MeSH terms
- Anodontia, Cleft Palate, Exons, Humans, Incontinentia Pigmenti, Mouth Abnormalities, Palate, Tooth Abnormalities, Tooth Eruption, Gene Deletion, I-kappa B Kinase
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
