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Cited by 210Attention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional DevelopmentAutism Spectrum Disorder Research

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Predictors of persistence of ADHD into adulthood: a systematic review of the literature and meta-analysis

Caye, Arthur, Spadini, Alex V., Karam, Rafael G., Grevet, Eugenio H., Rovaris, Diego L, Bau, Claiton H. D., Rohde, Luis A., Kieling, Christian·2016·European Child & Adolescent Psychiatry
DOI 10.1007/s00787-016-0831-8
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Abstract

Attention-deficit/hyperactivity disorder (ADHD) is traditionally conceptualized as a neurodevelopmental disorder that continues into adulthood in up to half of diagnosed cases. In light of current evidence, factors associated with the course of the disorder remain unknown. We performed a systematic review of the literature searching for risk markers from childhood that predicted the persistence of ADHD into adulthood. We reviewed 26,168 abstracts and selected 72 for full-text review. We identified data from 16 studies, comprising 6 population-based retrospective samples and 10 clinical follow-ups. We performed meta-analyses of factors evaluated by at least three studies. Severity of ADHD (OR 2.33, 95 % CI = 1.6-3.39, p < 0.001), treatment for ADHD (OR 2.09, 95 % CI = 1.04-4.18, p = 0.037), comorbid conduct disorder (OR 1.85, 95 % CI = 1.06-3.24, p = 0.030), and comorbid major depressive disorder (OR 1.8, 95 % CI = 1.1-2.95, p = 0.019) emerged as predictors already presented in childhood for ADHD persistence into adulthood. Further, we suggest that cohort studies should be designed to clarify such an important question for research and clinical practice.

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Metadata

Authors
Caye, A., Spadini, A. V., Karam, R. G., Grevet, E. H., Rovaris, D. L., Bau, C. H. D., Rohde, L. A., & Kieling, C.
Affiliations
Universidade Federal do Rio Grande do Sul (BR)
Corresponding author
Kieling, Christian
ORCID
Venue
European Child & Adolescent Psychiatry
Publisher
Springer Science and Business Media LLC
Published
2016-03-28
Volume
25
Issue
11
Pages
1151-1159
ISSN
  • 1018-8827 (ISSN-L)
  • 1435-165X
DOI
10.1007/s00787-016-0831-8
OpenAlex
W2315535560
Cited by
210
References
38
Citations by year
2026: 24 · 2025: 20 · 2024: 14 · 2023: 18 · 2022: 27 · 2021: 29 · 2020: 23 · 2019: 14 · 2018: 18 · 2017: 16 · 2016: 6
FWCI
2.57
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • European Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
  • Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords
attention deficit hyperactivity disorder, ADHD persistence into adulthood, risk factors, ADHD symptom severity, ADHD treatment, major depressive disorder comorbidity
MeSH terms
Adolescent, Adult, Attention Deficit Disorder with Hyperactivity, Child, Humans, Comorbidity

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