Neural Mechanisms of Alarm Pheromone Signaling
Open accessAbstract
Alarm pheromones are important semiochemicals used by many animal species to alert conspecifics or other related species of impending danger. In this review, we describe recent developments in our understanding of the neural mechanisms underlying the ability of fruit flies, zebrafish and mice to mediate the detection of alarm pheromones. Specifically, alarm pheromones are detected in these species through specialized olfactory subsystems that are unique to the chemosensitive receptors, second messenger-signaling and physiology. Thus, the alarm pheromones appears to be detected by signaling mechanisms that are distinct from those seen in the canonical olfactory system.
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There are at least two reasons to believe that rats or mice display social transmission of information about threats: it is described in many other species, and laboratory mice and rats emit alarm calls in different modalities.
“However, there are at least two reasons to believe that they display this form of social behaviors.First, it was described in many other species, including birds, monkeys and zebrafish.148,149 Secondly, laboratory mice and rats do emit alarm calls in different modalities (see below).”
From Ecological validity of social interaction tests in rats and mice (2019) · cites this paper as [148]
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Ecological validity of social interaction tests in rats and mice
Kondrakiewicz, K., Kostecki, M., Szadzińska, W., & Knapska, E. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12525 · Cited by 136 · see citing works
- Authors
- Enjin, A., & Suh, G. S.-B.
- Affiliations
- New York University (US)
- Corresponding author
- Enjin, Anders
- Suh, Greg Seong-Bae
- Venue
- Molecules and Cells
- Publisher
- Elsevier BV
- Published
- 2013-03
- Volume
- 35
- Issue
- 3
- Pages
- 177-181
- ISSN
- 0219-1032 (ISSN-L)
- 1016-8478
- PMC
- PMC3887916
- OpenAlex
- W2013653872
- Cited by
- 28
- References
- 61
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 2 · 2013: 2
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Molecules and Cells (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Funders
- Wenner-Gren Stiftelserna
- National Institutes of Health
- National Institute on Deafness and Other Communication Disorders
- National Institute of General Medical Sciences (R01GM089746)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect Pheromone Research and Control
- Keywords
- alarm pheromone, semiochemicals, odor detection, second messenger signaling, neural mechanisms, fruit flies, zebrafish, mice
- MeSH terms
- Animals, Animal Communication, Chemoreceptor Cells, Pheromones, Smell, Ultrasonography, Second Messenger Systems, Olfactory Perception
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