The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Antimicrobial effect of photodynamic therapy using a highly pure chlorin e6
Abstract
The aim of the present study is to evaluate the antimicrobial effect of photodynamic therapy (PDT) using a highly pure chlorin e(6) (Ce(6)), against various pathogenic bacteria. To examine the antimicrobial effect of Ce(6)-mediated PDT against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Salmonella enterica serovar Typhimurium, inhibition zone formation, CFU quantification, and bacterial viability were evaluated. Inhibition zone analysis showed that Ce(6)-mediated PDT is very effective to inhibit the growth of S. aureus and P. aeruginosa, but has only minor effect to E. coli and S. Typhimurium, which was dependent on the energy density of laser and dose of Ce(6). Ce(6)-mediated PDT also nearly inhibited the colony formation of S. aureus and P. aeruginosa, and partially inhibited that of E. coli and S. Typhimurium. In addition, the number of viable bacteria decreased greatly after PDT application with LS-chlorin e6 of 10 microM and laser and energy density of 20 J/cm(2). These results show that Ce(6)-mediated PDT can be an effective alternative for antimicrobial treatment.
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In the citing paper
“However, the Ce6-mediated PDT showed a lesser effect on Escherichia coli and Salmonella enterica serovar Typhimurium even with 20 μM of Ce6 and a laser of energy density greater than 30 J/cm2.”
From Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp. (2023) · cites this paper as [147]
In the citing paper
“Ce6 derived from Chlorella ellipsoidea effectively inhibited the growth of S. aureus and Pseudomonas aeruginosa after PDT application with 10 μM of Ce6 and a laser of energy density of 20 J/cm2 [147].”
From Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp. (2023) · cites this paper as [147]
Citations
Cites
Photodynamic therapy: a new antimicrobial approach to infectious disease?
Hamblin, M. R., & Hasan, T. G. (2004) · Photochemical & Photobiological Sciences · doi:10.1039/b311900a · Cited by 2,040
Photodynamic antimicrobial chemotherapy (PACT)
WAINWRIGHT, M. S. (1998) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/42.1.13 · Cited by 1,241
Jori, G., Fabris, C., Soncin, M., Ferro, S., Coppellotti, O., Dei, D., Fantetti, L., Chiti, G., & Roncucci, G. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20361 · Cited by 829
INACTIVATION OF GRAM‐NEGATIVE BACTERIA BY PHOTOSENSITIZED PORPHYRINS
Nitzan, Y., Gutterman, M., Malik, Z., & Ehrenberg, B. (1992) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1992.tb04213.x · Cited by 340
Malik, Z., Hanania, J., & Nitzan, Y. (1990) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/1011-1344(90)85044-w · Cited by 317
Hamblin, M. R. (2002) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkf053 · Cited by 269
Photodynamic therapy in oncology
Kinsella, T. J., Colussi, V., Oleinick, N. L., & Sibata, C. H. (2001) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2.6.917 · Cited by 218
Phage Therapy of Local and Systemic Disease Caused by Vibrio vulnificus in Iron-Dextran-Treated Mice
Cerveny, K. E., DePaola, A., Duckworth, D. H., & Gulig, P. A. (2002) · Infection and Immunity · doi:10.1128/iai.70.11.6251-6262.2002 · Cited by 182
Tegos, G. P., Anbe, M., Yang, C., et al. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.4.1402-1410.2006 · Cited by 173
Peloi, L. S., Soares, R. R. S., Biondo, C. E. G., de Souza, V. R., Hioka, N., & Kimura, E. M. (2008) · Journal of Biosciences · doi:10.1007/s12038-008-0040-9 · Cited by 132
Cited by
Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp.
Abreu, A. P., Martins, R., & Nunes, J. (2023) · Bioengineering · doi:10.3390/bioengineering10080955 · Cited by 119
Metadata
- Authors
- Park, J.-H., Moon, Y.-H., Bang, I.-S., Kim, Y.-C., Kim, S.-A., Ahn, S.-G., & Yoon, J.-H.
- Affiliations
- Konyang University (KR)
- Chosun University (KR)
- Gwangju Institute of Science and Technology (KR)
- Dongguk University (KR)
- Corresponding author
- Ahn, Sang-Gun
- Yoon, Jung-Hoon
- Venue
- Lasers in Medical Science
- Published
- 2010-04-23
- Volume
- 25
- Issue
- 5
- Pages
- 705-710
- ISSN
- 0268-8921 (ISSN-L)
- 1435-604X
- OpenAlex
- W2075626728
- Cited by
- 78
- References
- 22
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 6 · 2022: 3 · 2021: 6 · 2020: 3 · 2019: 6 · 2018: 6 · 2017: 10 · 2016: 2 · 2015: 6 · 2014: 5 · 2013: 6 · 2012: 7
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Lasers in Medical Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Photodynamic Therapy Research Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
- Keywords
- photodynamic therapy, chlorin e6, antimicrobial activity, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella typhimurium, bacterial viability, laser fluence, antimicrobial photodynamic therapy
- MeSH terms
- Bacteria, Chlorophyllides, Escherichia coli, Photochemotherapy, Porphyrins, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, Photosensitizing Agents, Microbial Viability, Bacterial Load
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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