Oncogenic human papillomavirus is not helpful for cytology screening of the precursor lesions of anal cancers in Taiwanese men who are infected with human immunodeficiency virus.

Cheng, Shu-Hsing; Wang, Chi-Chao; Chang, Shih-Lung; Chu, Fang-Yeh; Hsueh, Yu-Mei

doi:10.1007/s10147-015-0804-9

Cited by 23Cervical Cancer and HPV ResearchColorectal and Anal CarcinomasViral-associated cancers and disorders

Oncogenic human papillomavirus is not helpful for cytology screening of the precursor lesions of anal cancers in Taiwanese men who are infected with human immunodeficiency virus.

Cheng, Shu-Hsing, Wang, Chi-Chao, Chang, Shih-Lung, Chu, Fang-Yeh, Hsueh, Yu-Mei·2015·International Journal of Clinical Oncology

DOI 10.1007/s10147-015-0804-9

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Abstract

Background Homosexual men infected with human immunodeficiency virus (HIV) are at increased risk of developing anal cancer. The aim of this study was to assess the clinical sensitivity of anal cytology analysis and oncogenic human papillomavirus (HPV) detection for predicting histological anal intraepithelial neoplasia.Methods Between March 2011 and December 2013, we enrolled 196 HIV-positive men in Taoyuan General Hospital, Taiwan. We analyzed the results of thin-preparation anal Pap smears, HPV genotyping, and histology of anoscopic biopsy samples.Results The mean age (±standard deviation) was 31.43 (±8.74) years. The proportion (95 % confidence interval) with abnormal thin-preparation anal cytology was 36.2 % (29.8-43.2 %): 16.8 % (12.2-22.7 %) atypical squamous cells of undetermined significance, 14.8 % (10.5-20.4 %) low-grade squamous intraepithelial lesions, and 4.6 % (2.4-8.5 %) high-grade squamous intraepithelial lesions. At least one HPV genotype was detected in 90.8 % of subjects, and the mean number of HPV infection types was 4.41 (±3.24).The frequency of histological high-grade anal intraepithelial lesions was 7.14 % (95 % confidence interval 4.3-11.6 %). Anal cytology yielding atypical squamous cells of undetermined significance or higher grades resulted in a sensitivity of 64.3 %, specificity of 65.9 %, positive predictive value of 12.7 %, and negative predictive value of 96 %. Using both oncogenic HPV and cytology did not provide better performance.Conclusions Anal cytology yielding atypical squamous cells of undetermined significance or higher grades could detect two-thirds of high-grade anal intraepithelial neoplasias in HIV-infected men and should be promoted for anal cancer prevention.

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Sensitivity and specificity of anal cytology to detect HSIL are limited (sensitivity 55%-89% and specificity 40%-67%).
“Sensitivity and specificity of anal cytology to detect HSIL are limited (sensitivity 55%–89% and specificity 40%–67%) (1286–1291).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1290]
HPV tests (using high-risk HPV types) are not clinically useful for anal cancer screening because of a high prevalence of anal HPV infection among populations at high risk, particularly MSM.
“HPV tests (using high-risk HPV types) are not clinically useful for anal cancer screening because of a high prevalence of anal HPV infection among populations at high risk, particularly MSM (1278,1289,1290).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1290]

The 2001 Bethesda System<SUBTITLE>Terminology for Reporting Results of Cervical Cytology</SUBTITLE>
Solomon, D. (2002) · JAMA · doi:10.1001/jama.287.16.2114 · Cited by 3,104 · see citing works
Natural History of Cervicovaginal Papillomavirus Infection in Young Women
Ho, G. Y. F., Bierman, R., Beardsley, L., Chang, C. J., & Burk, R. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380703 · Cited by 2,329 · see citing works
NATURAL HISTORY OF CERVICOVAGINAL PAPILLOMAVIRUS INFECTION IN YOUNG WOMEN
Loria, G. R., Ierman, R. O. B., Eardsley, L. E. B., & Hang, H. J. C. (1998) · Cited by 1,887 · see citing works
The Pap Test and Bethesda 2014
Nayar, R., & Wilbur, D. C. (2015) · Journal of the American Society of Cytopathology · doi:10.1016/j.jasc.2015.03.003 · Cited by 1,149 · see citing works
Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
Machalek, D. A., Poynten, M., Jin, F., Fairley, C. K., Farnsworth, A., Garland, S. M., Hillman, R. J., Petoumenos, K., Roberts, J. M., Tabrizi, S. N., et al. (2012) · The Lancet Oncology · doi:10.1016/s1470-2045(12)70080-3 · Cited by 970 · see citing works
Incidence of Types of Cancer among HIV-Infected Persons Compared with the General Population in the United States, 1992–2003
Patel, P., Hanson, D. L., Sullivan, P. S., Novak, R. M., Moorman, A. C., Tong, T. C., Holmberg, S. D., Brooks, J. T., & for the Adult and Adolescent Spectrum of Disease Project and HIV Outpatient Study Investigators* (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-10-200805200-00005 · Cited by 940 · see citing works
Risk of Anal Cancer in HIV-Infected and HIV-Uninfected Individuals in North America
Silverberg, M. J., Lau, B., Justice, A. C., Engels, E. A., Gill, M. J., Goedert, J. J., Kirk, G. D., DʼSouza, G., Bosch, R. J., Brooks, J. T., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cir1012 · Cited by 518 · see citing works
Incidence and Epidemiology of Anal Cancer in the Multicenter AIDS Cohort Study
DʼSouza, G., Wiley, D. J., Li, X., Chmiel, J. S., Margolick, J. B., Cranston, R., & Jacobson, L. P. (2008) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31817aebfe · Cited by 341 · see citing works
Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy
Piketty, C., Selinger‐Leneman, H., Grabar, S., Duvivier, C., Bonmarchand, M., Abramowitz, L., Costagliola, D. G., & Mary‐Krause, M. (2008) · AIDS · doi:10.1097/qad.0b013e3283023f78 · Cited by 277 · see citing works
Anal Cancer Incidence: Genital Warts, Anal Fissure or Fistula, Hemorrhoids, and Smoking
Holly, E. A., Whittemore, A. S., Aston, D. A., Ahn, D. K., Nickoloff, B. J., & Kristiansen, J. J. (1989) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/81.22.1726 · Cited by 262 · see citing works
Anal cancer and cervical cancer screening: Key differences
Darragh, T. M., & Winkler, B. (2010) · Cancer Cytopathology · doi:10.1002/cncy.20126 · Cited by 219 · see citing works
Anal cancers among HIV-infected persons: HAART is not slowing rising incidence
Crum‐Cianflone, N. F., Hullsiek, K. H., Marconi, V. C., Ganesan, A., Weintrob, A., Barthel, R., & Agan, B. K. (2010) · AIDS · doi:10.1097/qad.0b013e328331f6e2 · Cited by 195 · see citing works
Performance Characteristics of Anal Cytology and Human Papillomavirus Testing in Patients with High-Resolution Anoscopy-Guided Biopsy of High-Grade Anal Intraepithelial Neoplasia
Berry, J. M., Palefsky, J. M., Jay, N., Cheng, S., Darragh, T. M., & Chin-Hong, P. V. (2009) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e31819793d9 · Cited by 191 · see citing works
Risk factors for genital HPV DNA in men resemble those found in women: a study of male attendees at a Danish STD clinic
Svare, E. I. (2002) · Sexually Transmitted Infections · doi:10.1136/sti.78.3.215 · Cited by 188 · see citing works
Anal carcinoma in human immunodeficiency virus-positive men: results of a prospective study from Germany
Kreuter, A., Potthoff, A. V., Brockmeyer, N. H., Gambichler, T., Swoboda, J., Stücker, M., Schmitt, M., Pfister, H., Wieland, U., & German Competence Network HIV/AIDS (2010) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.09712.x · Cited by 179 · see citing works
Chapter 6: Immunosuppression and Co-infection with HIV
Palefsky, J. M., & Holly, E. A. (2003) · JNCI Monographs · doi:10.1093/oxfordjournals.jncimonographs.a003481 · Cited by 179 · see citing works
The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening
Salit, I. E., Lytwyn, A., Raboud, J., Sano, M., Chong, S., Diong, C. C., Chapman, W. B., Mahony, J. B., & Tinmouth, J. (2010) · AIDS · doi:10.1097/qad.0b013e328339e592 · Cited by 170 · see citing works
Increased Incidence of Squamous Cell Anal Cancer Among Men With AIDS in the Era of Highly Active Antiretroviral Therapy
Diamond, C. A., Taylor, T. H., Aboumrad, T. L., Bringman, D., & Anton‐Culver, H. (2005) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000162366.60245.02 · Cited by 164 · see citing works
HAART and Progression to High-Grade Anal Intraepithelial Neoplasia in Men Who Have Sex with Men and Are Infected with HIV
de Pokomandy, A., Rouleau, D., Ghattas, G., Trottier, H., Vézina, S., Cote, P., Macleod, J., Allaire, G. S., Hadjeres, R., Franco, E. L., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir064 · Cited by 161 · see citing works
The value of anal cytology and human papillomavirus typing in the detection of anal intraepithelial neoplasia: a review of cases from an anoscopy clinic
Fox, P. A. (2005) · Sexually Transmitted Infections · doi:10.1136/sti.2003.008318 · Cited by 153 · see citing works
HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues
Stanley, M., Winder, D. M., Sterling, J. C., & Goon, P. K. C. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-398 · Cited by 97 · see citing works
Self-Collected Versus Clinician-Collected Anal Cytology Specimens to Diagnose Anal Intraepithelial Neoplasia in HIV-Positive Men
Cranston, R., Darragh, T. M., Holly, E. A., Jay, N., Berry, J. M., Costa, M. D., Efird, J. T., & Palefsky, J. M. (2004) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200408010-00004 · Cited by 94 · see citing works
The pathology and molecular biology of anal intraepithelial neoplasia: comparisons with cervical and vulvar intraepithelial carcinoma
Zbar, A. P., Fenger, C., Efron, J., Beer-Gabel, M., & Wexner, S. D. (2002) · International Journal of Colorectal Disease · doi:10.1007/s00384-001-0369-0 · Cited by 92 · see citing works
Cost-effectiveness of screening for anal precancers in HIV-positive men
Lam, J. M., Hoch, J. S., Tinmouth, J., Sano, M., Raboud, J., & Salit, I. E. (2010) · AIDS · doi:10.1097/qad.0b013e3283434594 · Cited by 89 · see citing works
NATURAL HISTORY OF ANAL CYTOLOGIC ABNORMALITIES AND PAPILLOMAVIRUS INFECTION AMONG HOMOSEXUAL MEN WITH GROUP IV HIV DISEASE
Palefsky, J. M., Holly, E. A., Gonzales, J., Lamborn, K. R., & Hollander, H. (1992) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-199212000-00009 · Cited by 82 · see citing works
Human papillomavirus genotyping, human papillomavirus mRNA expression, and p16/Ki-67 cytology to detect anal cancer precursors in HIV-infected MSM
Wentzensen, N., Follansbee, S., Borgonovo, S., Tokugawa, D., Schwartz, L. M., Lorey, T. S., Sahasrabuddhe, V. V., LaMere, B. J., Gage, J. C., Fetterman, B. J., et al. (2012) · AIDS · doi:10.1097/qad.0b013e328359f255 · Cited by 76 · see citing works
Human Papillomavirus Genotype Attribution and Estimation of Preventable Fraction of Anal Intraepithelial Neoplasia Cases Among HIV-Infected Men Who Have Sex With Men
Sahasrabuddhe, V. V., Castle, P. E., Follansbee, S., Borgonovo, S., Tokugawa, D., Schwartz, L. M., Lorey, T. S., LaMere, B. J., Gage, J. C., Fetterman, B. J., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis694 · Cited by 60 · see citing works
Anal intraepithelial neoplasia: review and recommendations for screening and management
Smyczek, P., Singh, A. E., & Romanowski, B. (2013) · International Journal of STD & AIDS · doi:10.1177/0956462413481527 · Cited by 46 · see citing works
Anal condylomas in men. 1. Histopathological and virological assessment.
Syrjänen, S., von Krogh, G., & Syrjänen, K. J. (1989) · Sexually Transmitted Infections · doi:10.1136/sti.65.4.216 · Cited by 44 · see citing works
Detection of Oncogenic Human Papillomavirus and Other Predictors of Anal High-Grade Dysplasia in Men Who Have Sex with Men with Abnormal Cytology
Goldstone, S. E., Enyinna, C. S., & Davis, T. W. (2009) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e31819736aa · Cited by 43 · see citing works
Detection of Oncogenic Human Papillomavirus Impacts Anal Screening Guidelines in Men Who Have Sex With Men
Goldstone, S. E., & Moshier, E. L. (2010) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e3181e10842 · Cited by 42 · see citing works
Anal cytological abnormalities and epidemiological correlates among men who have sex with men at risk for HIV-1 infection
Donà, M. G., Benevolo, M., Vocaturo, A., Palamara, G., Latini, A., Giglio, A., Moretto, D., Rollo, F., Impara, G., Ensoli, F., et al. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-476 · Cited by 33 · see citing works
Anal cytology as a predictor of anal intraepithelial neoplasia in HIV‐positive men and women
Betancourt, E. M., Wahbah, M. M., Been, L. C., Chiao, E. Y., Citron, D. R., & Laucirica, R. (2013) · Diagnostic Cytopathology · doi:10.1002/dc.22941 · Cited by 33 · see citing works
Ubiquitination and proteasome degradation of the E6 proteins of human papillomavirus types 11 and 18
Stewart, D. (2004) · Journal of General Virology · doi:10.1099/vir.0.19679-0 · Cited by 31 · see citing works
High Prevalence of Anal Human Papillomavirus Infection and Associated Risky Behaviors in Men Infected with Human Immunodeficiency Virus in Taiwan
Yu, C.-T., Chao, S., Lee, H., Chou, C.-Y., Ko, W., Liu, H.-Y., Lai, Y.-Y., Lee, N., Chang, C., & Ko, N. (2012) · AIDS and Behavior · doi:10.1007/s10461-012-0173-6 · Cited by 25 · see citing works
Distribution of human papillomavirus genotypes, assessment of HPV 16 and 18 viral load and anal related lesions in HIV positive patients: A cross‐sectional analysis
Tamalet, C., Obry‐Roguet, V., Ressiot, E., Brégigeon, S., Grande, J. D., & Poizot‐Martin, I. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23831 · Cited by 23 · see citing works
Screening und Therapie der analen intraepithelialen Neoplasie (AIN) und des Analkarzinoms bei HIV-Infektion
Kreuter, A., Reimann, G., Eßer, S., Rasokat, H., Hartmann, M., Swoboda, J., Conant, M. A., Tschachler, E., Arasteh, K., Altmeyer, P., et al. (2003) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-2003-42360 · Cited by 17 · see citing works
Screening and risk factors for anal cancer precursors in men infected with HIV in Taiwan
Cheng, S., Chu, F., Wang, C., & Hsueh, Y. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23825 · Cited by 16 · see citing works
Influence of age and CD4+ T cell counts on the prevalence of genital human papillomavirus infection among HIV‐seropositive men who have sex with men in Taiwan
Cheng, S., Chu, F., Lin, Y., & Hsueh, Y. (2012) · Journal of Medical Virology · doi:10.1002/jmv.23413 · Cited by 14 · see citing works
Prevalence and predictors of high-grade anal intraepithelial neoplasia in a community-based sample of homosexual men
Hillman, R. J., van Leeuwen, M. T., Vajdic, C. M., McHugh, L. C., Prestage, G., Botes, L. P., Zablotska, I., Medley, G., Tabrizi, S. N., Grulich, A. E., et al. (2012) · Sexual Health · doi:10.1071/sh11139 · Cited by 13 · see citing works
14. Natural history of high-grade squamous intraepithelial lesions (HSIL) in homosexual men: early evidence from the Study of the Prevention of Anal Cancer (SPANC)
Grulich, A. E., Jin, F., Poynten, I. M., Roberts, J. M., Farnsworth, A., Templeton, D. J., Tabrizi, S. N., Garland, S. M., Fairley, C. K., & Hillman, R. J. (2013) · Sexual Health · doi:10.1071/shv10n6ab14 · Cited by 4 · see citing works

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Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies
Wei, F., Gaisa, M. M., DʼSouza, G., Xia, N., Giuliano, A. R., Hawes, S. E., Gao, L., Cheng, S., Donà, M. G., Goldstone, S. E., et al. (2021) · The Lancet HIV · doi:10.1016/s2352-3018(21)00108-9 · Cited by 220 · see citing works
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for Anal Squamous Cell Cancers (Revised 2018)
Stewart, D. B., Gaertner, W. B., Glasgow, S. C., Herzig, D. O., Feingold, D. L., & Steele, S. R. (2018) · Diseases of the Colon & Rectum · doi:10.1097/dcr.0000000000001114 · Cited by 188 · see citing works
Anal cancer and intraepithelial neoplasia screening: A review
Leeds, I. L. (2016) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v8.i1.41 · Cited by 162 · see citing works
A systematic review and meta‐analysis of cytology and HPV‐related biomarkers for anal cancer screening among different risk groups
Clarke, M. A., Deshmukh, A. A., Suk, R., Roberts, J. M., Gilson, R. J. C., Jay, N., Stier, E. A., & Wentzensen, N. (2022) · International Journal of Cancer · doi:10.1002/ijc.34199 · Cited by 136 · see citing works
Strategies for screening and early detection of anal cancers: A narrative and systematic review and meta‐analysis of cytology, HPV testing, and other biomarkers
Clarke, M. A., & Wentzensen, N. (2018) · Cancer Cytopathology · doi:10.1002/cncy.22018 · Cited by 105 · see citing works
Anal Cancer Screening and Prevention: Summary of Evidence Reviewed for the 2021 Centers for Disease Control and Prevention Sexually Transmitted Infection Guidelines
Barroso, L. F., Stier, E. A., Hillman, R. J., & Palefsky, J. M. (2022) · Clinical Infectious Diseases · doi:10.1093/cid/ciac044 · Cited by 66 · see citing works
The Accuracy of Anal Swab–Based Tests to Detect High-Grade Anal Intraepithelial Neoplasia in HIV-Infected Patients: A Systematic Review and Meta-analysis
Lima, F. D. G., Viset, J. D., Leeflang, M., Limpens, J., Prins, J. M., & de Vries, H. J. C. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz191 · Cited by 31 · see citing works
Human Papillomavirus Genotypes Predict Progression of Anal Low-Grade Squamous Intraepithelial Lesions
Liu, Y., Sigel, K. M., & Gaisa, M. M. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiy463 · Cited by 29 · see citing works
Prevalence and Incidence of Human Papillomavirus Infection in Men Having Sex With Men Enrolled in a Pre-exposure Prophylaxis Study: A Sub-study of the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales “Intervention Préventive de l’Exposition aux Risques avec et pour les hommes Gays” Trial
Cotte, L., Veyer, D. L., Charreau, I., Péré, H., Cua, É., Carette, D., Chas, J., Capitant, C., Chidiac, C., Fléjou, J., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa002 · Cited by 23 · see citing works
High-risk human papillomavirus test in anal smears: can it optimize the screening for anal cancer?
Kimura, C. M. S., Nahas, C. S. R., Filho, E. V. D. S., Ribeiro, V. L., Segurado, A. A. C., Alcantara, F. F., Cecconello, I., & Nahas, S. C. (2020) · AIDS · doi:10.1097/qad.0000000000002795 · Cited by 19 · see citing works
Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future
Huang, S., Huang, H., Ku, S. W., Kuo, P.-H., Lin, K., Chen, G., Lee, C., Huang, Y., & Hung, C. (2024) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2024.11.003 · Cited by 18 · see citing works
Anal squamous intraepithelial lesions: an update and proposed management algorithm
Chittleborough, T. J., Tapper, R. I., Eglinton, T. W., & Frizelle, F. (2019) · Techniques in Coloproctology · doi:10.1007/s10151-019-02133-4 · Cited by 17 · see citing works
Multiple types of human papillomavirus infection and anal precancerous lesions in HIV-infected men in Taiwan: a cross-sectional study
Cheng, S., Liao, K., Wang, C., Cheng, C., & Chu, F. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019894 · Cited by 15 · see citing works
Efectividad del genotipado del virus del papiloma humano frente a la citología anal en la identificación de neoplasia intraepitelial de alto grado
Padilla‐España, L., Repiso‐Jiménez, J. B., Sánchez, F. F., Pereda, T., Rivas‐Ruiz, F., Fernández-Morano, T., Lima, J. D. L. T., Palma, F., Redondo, M., & de Troya-Martín, M. (2016) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2016.02.003 · Cited by 10 · see citing works
Human papillomavirus infection and its role in the pathogenesis of anal cancer
Palefsky, J. M. (2017) · Seminars in Colon and Rectal Surgery · doi:10.1053/j.scrs.2017.04.001 · Cited by 8 · see citing works
Human papillomavirus infection and anal cytology in Taiwanese homosexual men with and without HIV infection
Wang, C., Chang, S.-L., Chu, F., Cheng, C., & Cheng, S. (2019) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.11162 · Cited by 8 · see citing works
Prevalence of HPV Infection Among Chinese Males With HPV‐Related Diseases: A Systematic Review and Meta‐Analysis
Tao, Z., Li, Z., Chen, B., Zhang, X., Bian, R., Velicer, C. M., Xu, A., & Sun, X. (2025) · Journal of Medical Virology · doi:10.1002/jmv.70469 · Cited by 6 · see citing works
A cross-sectional pilot study to define anal cancer risk factors in HIV-positive solid organ transplant recipients
Fuertes, I., Chivite, I., Cranston, R., Sánchez, E., de Lazzari, E., Marimón, L., Ordï, J., Miró, J. M., Blanco, J. L., & on behalf of the Hospital Clinic of Barcelona SOT in HIV-infected patients Working Group Investigators (2025) · Scandinavian Journal of Infectious Diseases · doi:10.1080/23744235.2025.2573412 · Cited by 1 · see citing works
Epidemiology and Pathogenesis of Anal Cancer
Roveda, J., & Smith, C. A. (2019) · Springer eBooks · doi:10.1007/978-3-030-20253-8_2 · Cited by 1 · see citing works
Dépistage et prévention du carcinome épidermoïde de l’anus
Gautier, M., & Siproudhis, L. (2017) · Côlon & Rectum · doi:10.1007/s11725-017-0696-4
Reprint of: Human papillomavirus infection and its role in the pathogenesis of anal cancer
Palefsky, J. M. (2018) · Seminars in Colon and Rectal Surgery · doi:10.1053/j.scrs.2018.11.015
O papel do teste de detecção de HPV de alto risco no rastreamento do câncer de ânus
Kimura, C. M. S. (2021) · doi:10.11606/t.5.2021.tde-27082021-114949

Screening and risk factors for anal cancer precursors in men infected with HIV in Taiwan
Cheng, S., Chu, F., Wang, C., & Hsueh, Y. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23825 · Cited by 16 · see citing works
Human papillomavirus infection and anal cytology in Taiwanese homosexual men with and without HIV infection
Wang, C., Chang, S.-L., Chu, F., Cheng, C., & Cheng, S. (2019) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.11162 · Cited by 8 · see citing works
Cytology as a screening tool for anal squamous intraepithelial lesion for HIV positive men: 10-year experience in an inner city hospital
Johnson, G., Nguyen, M. L., Krishnamurti, U., Seydafkan, S., Flowers, L., Ehdaivand, S., & Mošunjac, M. (2015) · Journal of the American Society of Cytopathology · doi:10.1016/j.jasc.2015.08.003 · Cited by 11 · see citing works
The role of oncogenic human papillomavirus determination for diagnosis of high-grade anal intraepithelial neoplasia in HIV-infected MSM.
Burgos, J., Hernández-Losa, J., Landolfi, S., Guelar, A., Dinares, M., Villar, J., Navarro, J., Ribera, E., Falcó, V., & Curran, A. (2017) · AIDS · doi:10.1097/qad.0000000000001605 · Cited by 32 · see citing works
The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening
Salit, I. E., Lytwyn, A., Raboud, J., Sano, M., Chong, S., Diong, C. C., Chapman, W. B., Mahony, J. B., & Tinmouth, J. (2010) · AIDS · doi:10.1097/qad.0b013e328339e592 · Cited by 170 · see citing works

Authors: Cheng, S.-H., Wang, C.-C., Chang, S.-L., Chu, F.-Y., & Hsueh, Y.-M.
Affiliations: Tao Yuan General Hospital (TW)
Far Eastern Memorial Hospital (TW)
Taipei Medical University (TW)
Corresponding author: Hsueh, Yu-Mei
ORCID: Cheng, Shu-Hsing
Chu, Fang-Yeh
Hsueh, Yu-Mei
Venue: International Journal of Clinical Oncology
Publisher: Springer Science and Business Media LLC
Published: 2015-02-25
Volume: 20
Issue: 5
Pages: 943-951
ISSN: 1341-9625 (ISSN-L)
1437-7772
DOI: 10.1007/s10147-015-0804-9
OpenAlex: W2016071321
Cited by: 23
References: 42
Citations by year: 2025: 2 · 2024: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 5 · 2017: 2 · 2016: 2
FWCI: 2.36
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: International Journal of Clinical Oncology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
Health Sciences › Medicine › Surgery › Colorectal and Anal Carcinomas
Health Sciences › Medicine › Oncology › Viral-associated cancers and disorders
Keywords: anal cancer, anal intraepithelial neoplasia, anal cytology, oncogenic human papillomavirus, HIV infection, men who have sex with men, HPV genotyping, squamous intraepithelial lesions, cancer screening, anal cancer prevention
MeSH terms: Adult, Anus Neoplasms, Cytodiagnosis, Humans, Male, Precancerous Conditions, Taiwan, HIV Infections, Papillomaviridae, Papillomavirus Infections, Early Detection of Cancer, Young Adult

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Oncogenic human papillomavirus is not helpful for cytology screening of the precursor lesions of anal cancers in Taiwanese men who are infected with human immunodeficiency virus.

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