The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study
Open accessAbstract
This study investigated the outcome of a 5-day headache-specific multidisciplinary treatment program (MTP) and the adherence to treatment recommendations in 295 prospectively recruited consecutive headache patients [210 migraine, 17 tension-type headache (TTH), 68 combination headache, including 56 medication-overuse headache (MOH)]. Headache frequency decreased from 13.4 (±8.8) to 8.8 (±8.0) days per month after 12-18 months. Forty-three percent of the participants fulfilled the primary outcome (reduction of headache frequency of ≥50%), which was less likely in patients with combination of migraine and TTH compared to migraine (OR = 3.136, p = 0.002) or TTH (OR = 1.029, n.s.). Increasing number of headache days per month (OR = 1.092, p ≤ 0.0001) and adherence to lifestyle modifications (OR = 1.269, p = 0.004) predicted primary outcome. 51 of 56 MOH patients were treated successfully. Thirty-five percent of the patients were adherent to pharmacological prophylaxis, 61% to relaxation therapy, and 72% to aerobic endurance sports. MTP is effective in headache treatment. Adherence to therapy was associated with better outcome.
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“A person-centered approach that integrates various intervention components is more effective [28,29] and may enhance personal control and efficacy in headache management [14].”
From Development and Evaluation of a Smartphone-Based Chatbot Coach to Facilitate a Balanced Lifestyle in Individuals With Headaches (BalanceUP App): Randomized Controlled Trial (2024) · cites this paper as [28]
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Citations
Cites
The International Classification of Headache Disorders: 2nd edition
Olesen, J., Goadsby, P. J., & Steiner, T. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00590-8 · Cited by 5,046
The global burden of headache: A documentation of headache prevalence and disability worldwide
Stovner, L., Hagen, K., Jensen, R., Katsarava, Z., Lipton, R., Scher, A., Steiner, T., & Zwart, J.-A. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01288.x · Cited by 2,444 · cited 1×
“Primary headaches, in particular migraine and tensiontype headache (TTH) cause severe burden of disease and create high costs in the health care system [1, 2].”
BackgroundSelf-citationOlesen, J. (2004) · Cephalalgia · doi:10.1111/j.1468-2982.2003.00824.x · Cited by 2,056
Interventions for enhancing medication adherence
Haynes, R. B., Ackloo, E., Sahota, N., McDonald, H. P., & Yao, X. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000011.pub3 · Cited by 1,244 · cited 1×
“Increasing the effectiveness of adherence might have more substantial impact on clinical outcome than improvement in specific medical treatments [27].”
Guidelines for Controlled Trials of Prophylactic Treatment of Chronic Migraine in Adults
Silberstein, S. D., Tfelt‐Hansen, P. C., Dodick, D., Limmroth, V., Lipton, R. B., Pascual, J., & Wang, S. J. (2008) · Cephalalgia · doi:10.1111/j.1468-2982.2008.01555.x · Cited by 303
Bigal, M., Rapoport, A., Sheftell, F., Tepper, S., & Lipton, R. (2004) · Cephalalgia · doi:10.1111/j.1468-2982.2004.00691.x · Cited by 275 · cited 1×
“Overuse of acute medication is responsible for the development or maintenance of chronic daily headache (CDH) and successful detoxification results in a 70% return to an episodic pattern of migraine [19].”
BackgroundClinical features, pathophysiology, and treatment of medication-overuse headache
Evers, S., & Marziniak, M. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70008-9 · Cited by 233 · cited 2×
“Longitudinal studies in academic headache clinics reported relapse rates from 30 to 41% 1 year after initial outpatient withdrawal treatment in MOH [5–8].”
BackgroundMedication Overuse Headache: Rates and Predictors for Relapse in a 4-year Prospective Study
Katsarava, Z., Muessig, M., Dzagnidze, A., Fritsche, G., Diener, H., & Limmroth, V. (2004) · Cephalalgia · doi:10.1111/j.1468-2982.2004.00789.x · Cited by 226 · cited 2×
“Longitudinal studies in academic headache clinics reported relapse rates from 30 to 41% 1 year after initial outpatient withdrawal treatment in MOH [5–8].”
BackgroundSelf-citationHolroyd, K. A., & Penzien, D. B. (1990) · Pain · doi:10.1016/0304-3959(90)91085-w · Cited by 223
Behavioral Management of Recurrent Headache: Three Decades of Experience and Empiricism
Penzien, D. B., Rains, J. C., & Andrasik, F. (2002) · Applied Psychophysiology and Biofeedback · doi:10.1023/a:1016247811416 · Cited by 162 · cited 1×
“The prophylactic effect of relaxation training in headache treatment is already proven in several studies [21–23].”
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Systematic Review of Migraine Prophylaxis Adherence and Persistence
Hepp, Z., Bloudek, L. M., & Varon, S. F. (2014) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2014.20.1.22 · Cited by 334
Ashina, S., Mitsikostas, D. D., Lee, M. J., Yamani, N., Wang, S., Messina, R., Ashina, H., Buse, D. C., Pozo‐Rosich, P., Jensen, R., et al. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00257-2 · Cited by 290
Self-citationPathophysiology, prevention, and treatment of medication overuse headache
Diener, H., Dodick, D. W., Evers, S., Holle, D., Jensen, R., Lipton, R. B., Porreca, F., Silberstein, S. D., & Schwedt, T. J. (2019) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30146-2 · Cited by 226
Self-citationLuedtke, K., Allers, A., Schulte, L. H., & May, A. (2015) · Cephalalgia · doi:10.1177/0333102415597889 · Cited by 232
Kaiser, U., Sabatowski, R., & Azad, S. C. (2015) · Der Schmerz · doi:10.1007/s00482-015-0030-4 · Cited by 160
Metadata
- Authors
- Gaul, C., van Doorn, C., Webering, N., Dlugaj, M., Katsarava, Z., Diener, H.-C., & Fritsche, G.
- Affiliations
- Essen University Hospital (DE)
- Corresponding author
- Gaul, Charly
- Venue
- The Journal of Headache and Pain
- Published
- 2011-05-05
- Volume
- 12
- Issue
- 4
- Pages
- 475-483
- ISSN
- 1129-2369 (ISSN-L)
- 1129-2377
- PMC
- PMC3139052
- OpenAlex
- W2017444456
- Cited by
- 156
- References
- 30
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 8 · 2023: 10 · 2022: 14 · 2021: 7 · 2020: 8 · 2019: 13 · 2018: 13 · 2017: 12 · 2016: 6 · 2015: 13 · 2014: 17 · 2013: 8 · 2012: 10
- FWCI
- 8.97
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- The Journal of Headache and Pain (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Keywords
- migraine, tension-type headache, medication overuse headache, medication adherence, headache frequency, lifestyle modification, pharmacological prophylaxis, relaxation training, headache centers
- MeSH terms
- Adolescent, Adult, Aged, Exercise Therapy, Female, Headache, Humans, Male, Middle Aged, Patient Compliance, Relaxation Therapy, Treatment Outcome, Pain Clinics, Young Adult
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