Cited by 55Antibiotic Use and ResistancePharmaceutical Economics and PolicyAntibiotic Resistance in Bacteria

Assessing the impact of national antibiotic campaigns in Europe

Open access
Filippini, M., Ortiz, L. G. González, Masiero, G.·2013·The European Journal of Health Economics

Abstract

Because of evidence of causal association between antibiotic use and bacterial resistance, the implementation of national policies has emerged as a interesting tool for controlling and reversing bacterial resistance. The aim of this study was to assess the impact of public policies on antibiotic use in Europe using a differences-in-differences approach. Comparable data on systemic antibiotics administered in 21 European countries are available for a 11-year period between 1997 and 2007. Data on national campaigns are drawn from the public health literature. We estimate an econometric model of antibiotic consumption with country fixed effects and control for the main socioeconomic and epidemiological factors. Lagged values and the instrumental variables approach are applied to address endogeneity aspects of the prevalence of infections and the adoption of national campaigns. We find evidence that public campaigns significantly reduce the use of antimicrobials in the community by 1.3-5.6 defined daily doses per 1,000 inhabitants yearly. This represents an impact of roughly 6.5-28.3 % on the mean level of antibiotic use in Europe between 1997 and 2007. The effect is robust across different measurement methods. Further research is needed to investigate the effectiveness of policy interventions targeting different social groups such as general practitioners or patients.

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Crossref · 10.1007/s10198-012-0404-9

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Authors
Filippini, M., Ortiz, L. G. G., & Masiero, G.
Affiliations
  • Università della Svizzera italiana (CH)
  • University of Bergamo (IT)
Corresponding author
Masiero, G.
Venue
The European Journal of Health Economics
Published
2012-06-17
Volume
14
Issue
4
Pages
587-599
ISSN
  • 1439-3972 (ISSN-L)
  • 1618-7598
  • 1618-7601
OpenAlex
W1984771562
Cited by
55
References
41
Citations by year
2026: 2 · 2025: 4 · 2024: 5 · 2023: 1 · 2022: 3 · 2021: 9 · 2020: 5 · 2019: 6 · 2018: 4 · 2016: 5 · 2015: 2 · 2014: 7 · 2013: 2
FWCI
3.83
Type
journal article
Language
en
Open access
Locations
  • The European Journal of Health Economics (publishedVersion)
  • PubMed (publishedVersion)
  • reroDoc Digital Library (submittedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • Aisberg (University of Bergamo) (submittedVersion, other-oa)
  • Aisberg (University of Bergamo) (submittedVersion)
  • Repository for Publications and Research Data (ETH Zurich) (submittedVersion, other-oa)
  • ETH Zürich Research Collection
Topics
  • Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Pharmaceutical Economics and Policy
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
Keywords
antibiotic use, antimicrobial resistance, public health policy, defined daily doses, policy impact assessment, European countries
MeSH terms
Anti-Bacterial Agents, Europe, Health Policy, Humans, Models, Theoretical, Practice Patterns, Physicians', Program Evaluation

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