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The Nuts and Bolts of Low-level Laser (Light) Therapy
Open accessAbstract
Soon after the discovery of lasers in the 1960s it was realized that laser therapy had the potential to improve wound healing and reduce pain, inflammation and swelling. In recent years the field sometimes known as photobiomodulation has broadened to include light-emitting diodes and other light sources, and the range of wavelengths used now includes many in the red and near infrared. The term “low level laser therapy” or LLLT has become widely recognized and implies the existence of the biphasic dose response or the Arndt-Schulz curve. This review will cover the mechanisms of action of LLLT at a cellular and at a tissular level and will summarize the various light sources and principles of dosimetry that are employed in clinical practice. The range of diseases, injuries, and conditions that can be benefited by LLLT will be summarized with an emphasis on those that have reported randomized controlled clinical trials. Serious life-threatening diseases such as stroke, heart attack, spinal cord injury, and traumatic brain injury may soon be amenable to LLLT therapy.
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Cites
A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530
Cited by
Near‐infrared light is neuroprotective in a monkey model of Parkinson disease
Darlot, F., Moro, C., El Massri, N., Chabrol, C., Johnstone, D. M., Reinhart, F., Agay, D., Torres, N., Bekha, D., Auboiroux, V., et al. (2016) · Annals of Neurology · doi:10.1002/ana.24542 · Cited by 114
Non‐mammalian Hosts and Photobiomodulation: Do All Life‐forms Respond to Light?
Hamblin, M. R., Huang, Y., & Heiskanen, V. (2019) · Photochemistry and Photobiology · doi:10.1111/php.12951 · Cited by 58
Self-citationMignon, C., Tobin, D. J., Zeitouny, M., & Uzunbajakava, N. E. (2018) · Biomedical Optics Express · doi:10.1364/boe.9.000852 · Cited by 43
Metadata
- Authors
- Chung, H., Dai, T., Sharma, S. K., Huang, Y.-Y., Carroll, J. D., & Hamblin, M. R.
- Venue
- Annals of Biomedical Engineering
- Published
- 2011-11-02
- Volume
- 40
- Issue
- 2
- Pages
- 516-533
- ISSN
- 0090-6964 (ISSN-L)
- 1573-9686
- OpenAlex
- W2132672239
- Cited by
- 1,624
- References
- 1
- FWCI
- 22.52
- Type
- journal article
- Language
- en
- Open access
- green
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- Chung, H., Dai, T., Sharma, S. K., Huang, Y.-Y., Carroll, J. D., & Hamblin, M. R. (2012). The Nuts and Bolts of Low-level Laser (Light) Therapy. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-011-0454-7
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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