Involvement of IGF binding protein 5 in prostaglandin E2-induced cellular senescence in human fibroblasts

The serial cultivation of human diploid cell strains

Hayflick, L., & Moorhead, P. S. (1961) · Experimental Cell Research · doi:10.1016/0014-4827(61)90192-6 · Cited by 8,508 · see citing works

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I., & Pereira-Smith, O. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.20.9363 · Cited by 7,477 · see citing works

Telomere measurement by quantitative PCR

Cawthon, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.10.e47 · Cited by 3,492 · see citing works

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

Campisi, J. (2005) · Cell · doi:10.1016/j.cell.2005.02.003 · Cited by 2,359 · see citing works

Cellular senescence in cancer and aging.

Collado, M., Blasco, M. A., & Serrano, M. (2007) · Cell · doi:10.1016/j.cell.2007.07.003 · Cited by 1,708 · see citing works

Diversity of group types, regulation, and function of phospholipase A2.

Dennis, E. A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36794-7 · Cited by 1,435 · see citing works

Senescence-messaging secretome: SMS-ing cellular stress

Kuilman, T., & Peeper, D. S. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2560 · Cited by 909 · see citing works

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7

Wajapeyee, N., Serra, R. W., Zhu, X., Mahalingam, M., & Green, M. R. (2008) · Cell · doi:10.1016/j.cell.2007.12.032 · Cited by 903 · see citing works

Prostaglandin E2 synthesis and secretion: The role of PGE2 synthases

Park, J. Y., Pillinger, M. H., & Abramson, S. B. (2006) · Clinical Immunology · doi:10.1016/j.clim.2006.01.016 · Cited by 793 · see citing works

Evolutionary medicine: from dwarf model systems to healthy centenarians?

Longo, V. D., & Finch, C. E. (2003) · Science · doi:10.1126/science.1077991 · Cited by 575 · see citing works

A Conserved Regulatory System for Aging

Kenyon, C. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00306-3 · Cited by 529 · see citing works

The role of chondrocyte senescence in osteoarthritis

Price, J. S., Waters, J. G., Darrah, C., Pennington, C., Edwards, D. R., Donell, S. T., & Clark, I. M. (2002) · Aging Cell · doi:10.1046/j.1474-9728.2002.00008.x · Cited by 386 · see citing works

Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against Stress

Yan, L., Vatner, D. E., O’Connor, J. P., Ivessa, A., Ge, H., Chen, W., Hirotani, S., Ishikawa, Y., Sadoshima, J., & Vatner, S. F. (2007) · Cell · doi:10.1016/j.cell.2007.05.038 · Cited by 354 · see citing works

Cyclooxygenases, prostanoids, and tumor progression

Wang, M., Honn, K. V., & Nie, D. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9096-5 · Cited by 344 · see citing works

Human osteoblast-derived insulin-like growth factor (IGF) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF action.

Andress, D. L., & Birnbaum, R. S. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41695-x · Cited by 343 · see citing works

The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene

Valentinis, B., Bhala, A., DeAngelis, T., Baserga, R., & Cohen, P. (1995) · Molecular Endocrinology · doi:10.1210/mend.9.3.7539889 · Cited by 327 · see citing works

Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

Paradis, V., Youssef, N., Dargère, D., Bâ, N., Bonvoust, F., Deschatrette, J., & Bedossa, P. (2001) · Human Pathology · doi:10.1053/hupa.2001.22747 · Cited by 314 · see citing works

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

Coppé, J.-P., Patil, C. K., Rodier, F., Sun, Y., Muñoz, D. P., Goldstein, J., Nelson, P. S., Desprez, P.-Y., & Campisi, J. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060301 · Cited by 302 · cited 2× · see citing works

Molecular inflammation hypothesis of aging based on the anti‐aging mechanism of calorie restriction

Chung, H. Y., Kim, H. J., Kim, K. W., Choi, J. S., & Yu, B. P. (2002) · Microscopy Research and Technique · doi:10.1002/jemt.10203 · Cited by 297 · see citing works

Inflammation-associated cancer: NF-κB is the lynchpin

Li, Q., Withoff, S., & Verma, I. M. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.04.003 · Cited by 268 · see citing works

Aging, Longevity, Inflammation, and Cancer

Caruso, C., Lio, D., Cavallone, L., & Franceschi, C. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1322.001 · Cited by 219 · see citing works

Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism

Kim, K. S., Seu, Y. B., Baek, S.-H., Kim, M. J., Kim, K. J., Kim, J. H., & Kim, J.-R. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-03-0280 · Cited by 199 · see citing works

Wound chronicity and fibroblast senescence – implications for treatment

Harding, K. G., Moore, K., & Phillips, T. J. (2005) · International Wound Journal · doi:10.1111/j.1742-4801.2005.00149.x · Cited by 169 · see citing works

Rapid techniques for DNA extraction from routinely processed archival tissue for use in PCR.

Sepp, R., Szabó, I., Uda, H., & Sakamoto, H. (1994) · Journal of Clinical Pathology · doi:10.1136/jcp.47.4.318 · Cited by 167 · see citing works

Inflammatory signaling and cellular senescence

Ren, J., Pan, J., Lu, Y.-P., Sun, P., & Han, J. (2008) · Cellular Signalling · doi:10.1016/j.cellsig.2008.10.011 · Cited by 149 · see citing works

Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology

Yoon, I. K., Kim, H. K., Kim, W., Song, I., Kim, W., Kim, S., Baek, S.-H., Kim, J. H., & Kim, J. (2004) · Experimental Gerontology · doi:10.1016/j.exger.2004.07.002 · Cited by 123 · see citing works

Gingival crevicular fluid interleukin‐1β, prostaglandin E2 and periodontal status in a community population

Zhong, Y., Slade, G. D., Beck, J. D., & Offenbacher, S. (2007) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2007.01057.x · Cited by 107 · see citing works

Success of prostaglandin E 2 in structure–function is a challenge for structure-based therapeutics

Serhan, C. N., & Levy, B. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1733589100 · Cited by 98 · see citing works

Regulation of replicative senescence by insulin‐like growth factor‐binding protein 3 in human umbilical vein endothelial cells

Kim, K. S., Kim, M., Seu, Y. B., Chung, H. Y., Kim, J. H., & Kim, J. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00315.x · Cited by 87 · see citing works

Prostaglandin E2 as a mediator of fever: the role of prostaglandin E (EP) receptors

Oka, T. (2004) · Frontiers in bioscience · doi:10.2741/1458 · Cited by 81 · see citing works

Evaluation of three methods for effective extraction of DNA from human hair

Suenaga, E., & Nakamura, H. (2005) · Journal of Chromatography B · doi:10.1016/j.jchromb.2004.11.028 · Cited by 80 · see citing works

[Endothelial cell senescence in human atherosclerosis: role of telomeres in endothelial dysfunction].

Minamino, T., Miyauchi, H., Yoshida, T., & Komuro, I. (2003) · PubMed · Cited by 75 · see citing works

Fountain of youth

Sage, L. J. (2007) · Nature Physics · doi:10.1038/nphys663 · Cited by 74 · see citing works

Normal or stress-induced fibroblast senescence involves COX-2 activity

Zdanov, S., Bernard, D., Debacq‐Chainiaux, F., Martien, S., Gosselin, K., Vercamer, C., Chelli, F., Toussaint, O., & Abbadie, C. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.04.033 · Cited by 68 · see citing works

Induction of Cellular Senescence by Secretory Phospholipase A2 in Human Dermal Fibroblasts through an ROS-Mediated p53 Pathway

Kim, H. J., Kim, K. S., Kim, S. H., Baek, S.-H., Kim, H. Y., Lee, C., & Kim, J. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/gln055 · Cited by 50 · see citing works

Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata

Pearson, W., Fletcher, R. S., Kott, L. S., & Hurtig, M. (2010) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-10-19 · Cited by 46 · see citing works

Impaired cAMP-mediated gene expression and decreased cAMP response element binding protein in senescent cells

Chin, J. H., Okazaki, M., Frazier, J. S., Hu, Z., & Hoffman, B. B. (1996) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1996.271.1.c362 · Cited by 43 · see citing works

Promoter-dependent and -independent Activation of Insulin-like Growth Factor Binding Protein-5 Gene Expression by Prostaglandin E2 in Primary Rat Osteoblasts

McCarthy, T. L., Casinghino, S. R., Mittanck, D. W., Ji, C.-H., & Rotwein, P. S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.12.6666 · Cited by 39 · see citing works

Prostaglandin E2promotes cell proliferationviaprotein kinase C/extracellular signal regulated kinase pathway‐dependent induction of c‐Myc expression in human esophageal squamous cell carcinoma cells

Yu, L., Wu, W. K. K., Li, Z. J., Li, H. T., Wu, Y. C., & Cho, C. H. (2009) · International Journal of Cancer · doi:10.1002/ijc.24607 · Cited by 36 · see citing works

Prognostic Factors in Arthrocentesis of the Temporomandibular Joint: Comparison of Bradykinin, Leukotriene B4, Prostaglandin E2, and Substance P Level in Synovial Fluid Between Successful and Unsuccessful Cases

Kaneyama, K., Segami, N., Sato, J., Fujimura, K., Nagao, T., & Yoshimura, H. (2007) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.joms.2005.10.068 · Cited by 36 · see citing works

Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts

Han, J. H., Roh, M. S., Park, C., Park, K. C., Cho, K. H., Kim, K. H., Eun, H. C., & Chung, J. H. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.02.002 · Cited by 35 · see citing works

PGE2 stimulates vascular smooth muscle cell proliferation via the EP2 receptor

Yau, L., & Zahradka, P. C. (2003) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(03)00096-0 · Cited by 35 · see citing works

Antinociceptive Effects of AS1892802, a Novel Rho Kinase Inhibitor, in Rat Models of Inflammatory and Noninflammatory Arthritis

Yoshimi, E., Kumakura, F., Hatori, C., Hamachi, E., Iwashita, A., Ishii, N., Terasawa, T., Shimizu, Y., & Takeshita, N. (2010) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.167924 · Cited by 34 · see citing works

Transcriptional regulation of insulin-like growth factor-binding protein-5 by prostaglandin E2 in osteoblast cells

Pash, J. M., & CANALIS, E. M. (1996) · Endocrinology · doi:10.1210/en.137.6.2375 · Cited by 32 · see citing works

Prostaglandin E2 inhibits the proliferation of human gingival fibroblasts via the EP2 receptor and Epac

Weinberg, E., Zeldich, E., Weinreb, M. M., Moses, O., Nemcovsky, C. E., & Weinreb, M. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22242 · Cited by 29 · see citing works

Age-associated Inflammatory Changes: Role of Nutritional Intervention

Meydani, S. N., & Wu, D. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00365.x · Cited by 24 · see citing works

Inhibition of PGE2 Production by Nimesulide Compared with Diclofenac in the Acutely Inflamed Joint of Patients with Arthritis

Duffy, T., Belton, O., Bresnihan, B., FitzGerald, O., & Fitzgerald, D. J. (2003) · Drugs · doi:10.2165/00003495-200363001-00005 · Cited by 21 · see citing works

Age-associated Inflammatory Changes: Role of Nutritional Intervention

Meydani, S. N., & Wu, D. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.dec.s213-s216 · Cited by 17 · see citing works

Downstream molecular events in the altered profiles of lysophosphatidic acid-induced cAMP in senescent human diploid fibroblasts

Jang, I., Rhim, J. A., Park, S. C., & Yeo, E. (2006) · Experimental & Molecular Medicine · doi:10.1038/emm.2006.17 · Cited by 15 · see citing works

Altered cAMP signaling induced by lysophosphatidic acid in senescent human diploid fibroblasts

Jang, I., Yeo, E., Park, J. A., Ahn, J. S., Park, J., Cho, K. A., Juhnn, Y., & Park, S. C. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00262-6 · Cited by 15 · see citing works

Lysophosphatidic Acid and Adenylyl Cyclase Inhibitor Increase Proliferation of Senescent Human Diploid Fibroblasts by Inhibiting Adenosine Monophosphate-Activated Protein Kinase

Rhim, J.-H., Jang, I., Song, K., Ha, M.-K., Cho, S.-C., Yeo, E., & Park, S. C. (2008) · Rejuvenation Research · doi:10.1089/rej.2008.0709 · Cited by 13 · see citing works

Adenylyl Cyclase 5: A New Clue in the Search for the "Fountain of Youth"?

Chester, J. A., & Watts, V. J. (2007) · Science s STKE · doi:10.1126/stke.4132007pe64 · Cited by 13 · see citing works

H�ufigkeit terminal differenzierter Fibroblasten in der Synovialmembran von Rheumapatienten

Schmid, M., Rodemann, H. P., & Aicher, W. K. (2004) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-004-0634-z · Cited by 7 · see citing works

The senescence-associated secretory phenotype and its regulation

Lopes-Paciencia, S., Saint-Germain, E., Rowell, M.-C., Ruiz, A. F., Kalegari, P., & Ferbeyre, G. (2019) · Cytokine · doi:10.1016/j.cyto.2019.01.013 · Cited by 601 · see citing works

Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis

Wiley, C. D., Sharma, R., Davis, S. S., Lopez-Dominguez, J. A., Mitchell, K. P., Wiley, S., Alimirah, F., Kim, D. E., Payne, T., Rosko, A., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.03.008 · Cited by 173 · see citing works

Signaling Pathways of the Insulin-like Growth Factor Binding Proteins

Baxter, R. C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad008 · Cited by 157 · see citing works

Vascular aging: Chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease

Bachschmid, M. M., Schildknecht, S., Matsui, R., Zee, R. S., Haeussler, D. J., Cohen, R. A., Pimental, D. R., & van der Loo, B. (2012) · Annals of Medicine · doi:10.3109/07853890.2011.645498 · Cited by 154 · see citing works

COVID-19 and cellular senescence

Schmitt, C. A., Tchkonia, T., Niedernhofer, L. J., Robbins, P. D., Kirkland, J. L., & Lee, S. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-022-00785-2 · Cited by 153 · see citing works

The Cyclooxygenase-2–Prostaglandin E2 Pathway Maintains Senescence of Chronic Obstructive Pulmonary Disease Fibroblasts

Dagouassat, M., Gagliolo, J.-M., Chrusciel, S., Bourin, M.-C., Duprez, C., Caramelle, P., Boyer, L., Hue, S., Stern, J.-B., Validire, P., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201208-1361oc · Cited by 120 · see citing works

Role of PGE-2 and Other Inflammatory Mediators in Skin Aging and Their Inhibition by Topical Natural Anti-Inflammatories

Fuller, B. B. (2019) · Cosmetics · doi:10.3390/cosmetics6010006 · Cited by 69 · see citing works

The ATF6α arm of the Unfolded Protein Response mediates replicative senescence in human fibroblasts through a COX2/prostaglandin E 2 intracrine pathway

Cormenier, J., Martin, N., Deslé, J., Salazar-Cardozo, C., Pourtier, A., Abbadie, C., & Pluquet, O. (2018) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2017.08.003 · Cited by 64 · see citing works

Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence

Alessio, N., Squillaro, T., Di Bernardo, G., Galano, G., De Rosa, R., Melone, M. A., Peluso, G., & Galderisi, U. (2020) · eLife · doi:10.7554/elife.54523 · Cited by 51 · see citing works

Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts

Martien, S., Pluquet, O., Vercamer, C., Malaquin, N., Martin, N., Gosselin, K., Pourtier, A., & Abbadie, C. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.04.005 · Cited by 50 · see citing works

Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47phox pathway

Tsai, M.-H., Lin, Z., Liang, C., Yen, F., Chiang, Y., & Lee, C. (2014) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2014.06.012 · Cited by 42 · see citing works

Local production of activated factor X in atherosclerotic plaque induced vascular smooth muscle cell senescence

Sanada, F., Muratsu, J., Otsu, R., Shimizu, H., Koibuchi, N., Uchida, K., Taniyama, Y., Yoshimura, S., Rakugi, H., & Morishita, R. (2017) · Scientific Reports · doi:10.1038/s41598-017-17508-6 · Cited by 41 · see citing works

Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5

Sanada, F., Taniyama, Y., Muratsu, J., Otsu, R., Iwabayashi, M., Carracedo, M., Rakugi, H., & Morishita, R. (2016) · Scientific Reports · doi:10.1038/srep35580 · Cited by 35 · see citing works

WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion

Lehmann, J., Narcisi, R., Franceschini, N., Chatzivasileiou, D., Boer, C. G., Koevoet, W. J. L. M., Putavet, D. A., Drabek, D., van Haperen, R., de Keizer, P. L. J., et al. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-04035-x · Cited by 35 · see citing works

Research update of adipose tissue-based therapies in regenerative dermatology

Bellei, B., Migliano, E., & Picardo, M. (2022) · Stem Cell Reviews and Reports · doi:10.1007/s12015-022-10328-w · Cited by 18 · see citing works

Cutaneous Redox Senescence

Sarandy, M. M., Gonçalves, R. V., & Valacchi, G. (2024) · Biomedicines · doi:10.3390/biomedicines12020348 · Cited by 16 · see citing works

Effects of SW033291 on the myogenesis of muscle-derived stem cells and muscle regeneration

Dong, Y., Li, Y., Zhang, C., Chen, H., Liu, L., & Chen, S. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-1574-5 · Cited by 14 · see citing works

Palmitate induces COX-2 expression via the sphingolipid pathway-mediated activation of NF-κB, p38, and ERK in human dermal fibroblasts

Oh, E., Yun, M., Kim, S. K., Seo, G., Bae, J. S., Joo, K. W., Chae, G. T., & Lee, S. (2013) · Archives of Dermatological Research · doi:10.1007/s00403-013-1434-6 · Cited by 10 · see citing works

Multiple Integrated Complementary Healing Approaches: Energetics & Light for bone

Gray, M. G., Lackey, B. R., Patrick, E. F., Gray, S. L., & Hurley, S. G. (2015) · Medical Hypotheses · doi:10.1016/j.mehy.2015.10.030 · Cited by 6 · see citing works

Meeting Report: International Symposium on the Genetics of Aging and Life History II

Artan, M., Hwang, A. B., Lee, S., & Nam, H. G. (2015) · Aging · doi:10.18632/aging.100762 · Cited by 4 · see citing works

Bulk RNA Barcode Sequencing Reveals Role of RNA Splicing in Aging Dermal Stem Cell Modulation by a Botanical Extract

Baumann, J., Vocat, V., Nowak, K., Zülli, F., Cuddapah, C., & Wandrey, F. (2024) · Cosmetics · doi:10.3390/cosmetics11050167

Noninvasive transdermal delivery of recombinant human elastin restores extracellular matrix homeostasis and repairs aged skin

Zhu, L., Huang, W., Shi, J., Wang, X., Li, F., Xiao, J., & Sun, X. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.179691

IGF Binding Protein-5 Induces Cell Senescence

Sanada, F., Taniyama, Y., Muratsu, J., Otsu, R., Shimizu, H., Rakugi, H., & Morishita, R. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00053 · Cited by 67 · see citing works

Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism

Kim, K. S., Seu, Y. B., Baek, S.-H., Kim, M. J., Kim, K. J., Kim, J. H., & Kim, J.-R. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-03-0280 · Cited by 199 · see citing works

Induction of Cellular Senescence by Secretory Phospholipase A2 in Human Dermal Fibroblasts through an ROS-Mediated p53 Pathway

Kim, H. J., Kim, K. S., Kim, S. H., Baek, S.-H., Kim, H. Y., Lee, C., & Kim, J. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/gln055 · Cited by 50 · see citing works

Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts

Mičutková, L., Diener, T., Li, C., Rogowska-Wrzesińska, A., Mück, C., Hütter, E., Weinberger, B., Grubeck‐Loebenstein, B., Roepstorff, P., Zeng, R., et al. (2011) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2011.07.005 · Cited by 39 · see citing works

Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts

Nojima, I., Hosoda, R., Toda, Y., Saito, Y., Ueda, N., Horimoto, K., Iwahara, N., Horio, Y., & Kuno, A. (2022) · Aging · doi:10.18632/aging.203999 · Cited by 22 · see citing works