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Cited by 1,214

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

The Generation R Study: design and cohort update 2017

Open access
Kooijman, Marjolein N., Kruithof, Claudia J., van Duijn, Cornelia M., Duijts, Liesbeth, Franco, Oscar H., van IJzendoorn, Marinus H., de Jongste, Johan C., Klaver, Caroline C. W., van der Lugt, Aad, Mackenbach, Johan P., Moll, Henriëtte A., Peeters, Robin P., Raat, Hein, Rings, Edmond H. H. M., Rivadeneira, Fernando, van der Schroeff, Marc P., Steegers, Eric A. P., Tiemeier, Henning, Uitterlinden, André G., Verhulst, Frank C., Wolvius, Eppo, Felix, Janine F., Jaddoe, Vincent W. V.·2016·European Journal of Epidemiology
DOI 10.1007/s10654-016-0224-9
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Abstract

The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their parents. Main exposures of interest include environmental, endocrine, genomic (genetic, epigenetic, microbiome), lifestyle related, nutritional and socio-demographic determinants. In total, 9778 mothers with a delivery date from April 2002 until January 2006 were enrolled in the study. Response at baseline was 61%, and general follow-up rates until the age of 10 years were around 80%. Data collection in children and their parents includes questionnaires, interviews, detailed physical and ultrasound examinations, behavioural observations, lung function, Magnetic Resonance Imaging and biological sampling. Genome and epigenome wide association screens are available. Eventually, results from the Generation R Study contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.

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Metadata

Authors
Kooijman, M. N., Kruithof, C. J., van Duijn, C. M., Duijts, L., Franco, O. H., van IJzendoorn, M. H., de Jongste, J. C., Klaver, C. C. W., van der Lugt, A., Mackenbach, J. P., Moll, H. A., Peeters, R. P., Raat, H., Rings, E. H. H. M., Rivadeneira, F., van der Schroeff, M. P., Steegers, E. A. P., Tiemeier, H., Uitterlinden, A. G., Verhulst, F. C., Wolvius, E., Felix, J. F., & Jaddoe, V. W. V.
Venue
European Journal of Epidemiology
Publisher
Springer Science and Business Media LLC
Published
2016-12
Volume
31
Issue
12
Pages
1243-1264
ISSN
  • 0393-2990 (ISSN-L)
  • 1573-7284
DOI
10.1007/s10654-016-0224-9
OpenAlex
W4210761116
Cited by
1,214
References
28
FWCI
111.02
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: The Generation R Study: design and cohort update 2017. https://app.cochat.ai/papers/10.1007/s10654-016-0224-9
The paper
Kooijman, M. N., Kruithof, C. J., van Duijn, C. M., Duijts, L., Franco, O. H., van IJzendoorn, M. H., de Jongste, J. C., Klaver, C. C. W., van der Lugt, A., Mackenbach, J. P., Moll, H. A., Peeters, R. P., Raat, H., Rings, E. H. H. M., Rivadeneira, F., van der Schroeff, M. P., Steegers, E. A. P., Tiemeier, H., Uitterlinden, A. G., . . . Jaddoe, V. W. V. (2016). The Generation R Study: design and cohort update 2017. European Journal of Epidemiology. https://doi.org/10.1007/s10654-016-0224-9

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.