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Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare
Open accessAbstract
Artificial intelligence-based (AI) technologies such as machine learning (ML) systems are playing an increasingly relevant role in medicine and healthcare, bringing about novel ethical and epistemological issues that need to be timely addressed. Even though ethical questions connected to epistemic concerns have been at the center of the debate, it is going unnoticed how epistemic forms of injustice can be ML-induced, specifically in healthcare. I analyze the shortcomings of an ML system currently deployed in the USA to predict patients’ likelihood of opioid addiction and misuse (PDMP algorithmic platforms). Drawing on this analysis, I aim to show that the wrong inflicted on epistemic agents involved in and affected by these systems’ decision-making processes can be captured through the lenses of Miranda Fricker’s account of hermeneutical injustice. I further argue that ML-induced hermeneutical injustice is particularly harmful due to what I define as an automated hermeneutical appropriation from the side of the ML system. The latter occurs if the ML system establishes meanings and shared hermeneutical resources without allowing for human oversight, impairing understanding and communication practices among stakeholders involved in medical decision-making. Furthermore and very much crucially, an automated hermeneutical appropriation can be recognized if physicians are strongly limited in their possibilities to safeguard patients from ML-induced hermeneutical injustice. Overall, my paper should expand the analysis of ethical issues raised by ML systems that are to be considered epistemic in nature, thus contributing to bridging the gap between these two dimensions in the ongoing debate.
Overview
CoChat Summary
TL;DR
The paper argues that machine-learning-based Prescription Drug Monitoring Programs (PDMPs) used in the USA to predict opioid misuse can inflict hermeneutical injustice on patients by imposing an unwarranted epistemic privilege, impairing understanding and communication, and disadvantaging hermeneutically marginalized groups. It names this ML-induced wrong “automated hermeneutical appropriation,” arguing that it also constrains physicians’ ability to safeguard patients.
Key findings
- The paper claims PDMP risk-scoring systems such as NarxCare meet three conditions for hermeneutical injustice: (1) the system holds an unwarranted epistemic privilege, (2) it impairs understanding and communication between patients and physicians, and (3) it produces hermeneutical disadvantage, especially for minorities, disadvantaged socio-economic groups, and patients with complex medical histories.
- It identifies “automated hermeneutical appropriation” as the ML system’s takeover of meaning-making and shared hermeneutical resources without human oversight, causing a misalignment between the system’s risk score and the patient’s own knowledge or the medically grounded meaning of addiction/substance use disorder.
- Drawing on Oliva (2022), the paper notes that risk scores use proxies such as distance traveled to a physician/pharmacy, number of specialists consulted, payment method, number of prescribers, history of sexual abuse or trauma, and criminal history; these can raise scores for innocuous reasons and can stigmatize or discriminate against already disadvantaged groups.
- The paper argues physicians are also affected: because PDMP outputs are legally enforced and hard to contest, physicians are expected to act on scores they cannot meaningfully influence, which undermines their stakeholder rights and limits their ability to counteract patients’ hermeneutical injustice through virtuous behavior.
Methods
- Conceptual and philosophical analysis applying Miranda Fricker’s account of hermeneutical injustice to ML systems in healthcare.
- Case study of automated PDMPs, especially NarxCare (Appriss/Bamboo Health), using secondary sources including Oliva (2022), Szalavitz (2021), Hildebran et al. (2014, 2016), Picco et al. (2021), and Haines et al. (2022).
- The argument proceeds by specifying and testing three conditions for hermeneutical injustice and by introducing “automated hermeneutical appropriation” as an explanatory concept.
Limitations
- The paper states that its focus is limited to whether patients in situations like Kathryn’s can be considered victims of hermeneutical injustice, setting aside other ethically problematic aspects such as privacy and informed consent.
- The paper states that more needs to be said about how these issues take shape in epistemic practices involving ML systems and that it hopes to encourage further research toward technically feasible solutions.
- Evident from the text: the analysis is conceptual and relies on secondary reports and literature rather than original empirical data, and it does not provide a technical validation or independent audit of NarxCare.
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Claims the paper makes
1 Valid · 2 Not valid · 41 Not checked · 94 Own results and interpretations
Every source the paper cites for this claim was checked and supports it.
In the paper
“That is to say, standard, non-ML-mediated epistemic practices between patients and physicians are already prone to put the patient in a position of epistemic weakness (Carel & Kidd, 2014; Carel et al., 2017).”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Epistemic injustice
What the sources say
- Supportedcites Carel & Kidd, 2014 source
Carel & Kidd (2014) argue throughout that ordinary, non-exceptional healthcare epistemic practices structurally disadvantage patients: the Introduction states that health professionals are considered epistemically privileged and 'decide which patient testimonies and interpretations to act upon', and that what patients say 'will therefore be assigned a deflated epistemic status'; Section 3 ('Epistemic privilege') describes 'an asymmetry in the relationship owing to an implicit hierarchy assigning the health professional (normally a physician) a high epistemic status' and claims the structures and discourses of contemporary healthcare practice 'privilege certain styles of articulating testimonies... in a way that structurally disables certain testimonial and hermeneutical activities'. The 'non-ML-mediated' qualifier is the citing paper's own contrast frame, not something attributed to this source; the substance of the claim (standard patient-physician epistemic practices already tend to place the patient in an epistemically weak position) is what our copy states, including the vicious-circle passage in Section 2. (LLM, conf=0.88)
- Supportedcites Carel et al., 2017 source
The paper states as its general thesis that ordinary clinical epistemic practices place patients at a disadvantage: 'A growing body of work has suggested that individuals suffering from ill health are more vulnerable to testimonial injustice, and this vulnerability exists across the different stages and epistemic practices of medical work' (Testimonial injustice, p. 3), and 'it is patients who have most to lose from the effects of such epistemic skewing' (Testimonial injustice, p. 4). It also notes that deferring to standard consultation roles — 'authoritative doctor' and 'submissive patient' — 'can on its own be epistemically unjust' (Evidence from patients, p. 7), and the Abstract (p. 1) holds patients to be 'particularly vulnerable to epistemic injustice'. The claim's hedged wording ('prone to', 'position of epistemic weakness') matches the source's level of confidence; the 'non-ML-mediated' contrast is the citing paper's own framing, not an attribution. (LLM, conf=0.85)
hedgedstates a possible cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Supported
In the paper
“As already mentioned, being NarxCare a proprietary algorithm, the possibilities to get meaningful insight into how it works and which criteria were decisive in estimating a patient’s high-risk score are very much constrained.”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Defining hermeneutical injustice in ML > Condition 2: Understanding and communication impairments
What the sources say
- Not matchedcites Oliva, 2022
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plainstates a cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, patients are confronted with a risk score that is treated as grounded knowledge that reliably mirrors their drug consumption levels.”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Defining hermeneutical injustice in ML > Condition 1: PDMPs and unwarranted epistemic privilege
plainstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Through careful consideration of the current flaws identified in this system's functioning, I show that it fulfills three fundamental conditions to identify forms of hermeneutical injustice suffered by patients affected by PDMPs' decision-making (“Defining epistemic injustice in ML” section).”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Introduction
boostedstates a cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
In the paper
“As a matter of fact, a study conducted by Picco et al. (2021, p. 8) reports that the number of patients being refused medical assistance and medication supply and of patients being discharged from practice has considerably increased due to the role taken up by PDMP platforms.”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Injustice in the production of knowledge: the case of PDMPs
What the sources say
- Not checked yetcites Picco et al., 2021 source
plainstates a cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
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Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Introduction
“i.e., Prediction Drug Monitoring Programs (PDMPs, see “Injustice in the production of knowledge: the case of PDMPs” section)”
§ Automated opioid risk scores: a case for machine learning-induced epistemic injustice in healthcare > Epistemic injustice
“ML-based Prescription Drug Monitoring Programs (PDMPs) are currently deployed throughout the US”
Citations
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High-performance medicine: the convergence of human and artificial intelligence
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Epistemic Injustice: Power and the Ethics of Knowing
Fricker, M. (2007) · doi:10.1093/acprof:oso/9780198237907.001.0001 · Cited by 9,198
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A guide to deep learning in healthcare
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The ethics of algorithms: Mapping the debate
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“…opacity translates into ethically relevant questions that concern, among others, the degree of trust we are justified to attribute to the outputs produced by these systems and under which circumstances we are epistemically and morally justified in acting upon them (Mittelstadt et al., 2016).”
BackgroundEhteshami Bejnordi, B., Veta, M., Johannes van Diest, P., van Ginneken, B., Karssemeijer, N., Litjens, G., van der Laak, J. A. W. M., and the CAMELYON16 Consortium, Hermsen, M., Manson, Q. F., et al. (2017) · JAMA · doi:10.1001/jama.2017.14585 · Cited by 3,293
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Research works printed but not linked: 3
- Hao, K (2020). Doctors are using AI to triage covid-19 patients. The tools may be here to stay. In MIT Technology Review. Retrieved July 27, 2021.
- Pozzi, G. & Durán, J. M. (under review). Informativeness and epistemic injustice in explanatory medical machine learning.
- Van den Hoven, J. (1998). Moral responsibility, public office and information technology. In: Public administration in an information age: a handbook (pp. 97–112).
Cited by
Epistemic Injustice in Generative AI
Kay, J., Kasirzadeh, A., & Mohamed, S. (2024) · Proceedings of the AAAI/ACM Conference on AI, Ethics, and Society · doi:10.1609/aies.v7i1.31671 · Cited by 76
Autonomy by Design: Preserving Human Autonomy in AI Decision-Support
Buijsman, S., Carter, S. E., & Bermúdez, J. P. (2025) · Philosophy & Technology · doi:10.1007/s13347-025-00932-2 · Cited by 43
Dirty Data Labeled Dirt Cheap: Epistemic Injustice in Machine Learning Systems
Hull, G. (2022) · Ethics and Information Technology · doi:10.1007/s10676-023-09712-y · Cited by 32
Mollema, W. J. T. (2025) · AI and Ethics · doi:10.1007/s43681-025-00801-w · Cited by 24
“As Pozzi [43] has carefully worked out regarding the example of machine learning (ML) systems mediating opioid (medical drugs) subscriptions, AI systems based on ML “hermeneutically appropriate” the resources it regulates and thereby “deprives human agents of understanding and hinders their…”
Socially disruptive technologies and epistemic injustice
Hopster, J. K. G. (2024) · Ethics and Information Technology · doi:10.1007/s10676-024-09747-9 · Cited by 22
Metadata
- Authors
- Pozzi, G.
- Affiliations
- Delft University of Technology (NL)
- Corresponding author
- Pozzi, Giorgia
- ORCID
- Pozzi, Giorgia
- Venue
- Ethics and Information Technology
- Published
- 2023-01-23
- Volume
- 25
- Issue
- 1
- Pages
- 3-3
- ISSN
- 1388-1957 (ISSN-L)
- 1572-8439
- PMC
- PMC9869303
- OpenAlex
- W4317739165
- Cited by
- 66
- References
- 42
- Citations by year
- 2026: 24 · 2025: 22 · 2024: 15 · 2023: 4
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- creativecommons.org/licenses/by/4.0 (tdm)
- creativecommons.org/licenses/by/4.0 (vor)
- Locations
- Ethics and Information Technology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Repository (Delft University of Technology) (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Horizon2020 (871042)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Ethics and Social Impacts of AI
- Social Sciences › Sociology and Political Science › Feminist Epistemology and Gender Studies
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- epistemic injustice, hermeneutical injustice, machine learning in healthcare, prescription drug monitoring programs, Miranda Fricker, algorithmic decision-making, physician oversight, medical ethics, AI ethics
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