The DOI matches its Crossref record; 84 of the 87 references it cites were found in a registry or an index.
Anxiety, Sensory Over-Responsivity, and Gastrointestinal Problems in Children with Autism Spectrum Disorders
Abstract
Children with autism spectrum disorders (ASD) experience high rates of anxiety, sensory processing problems, and gastrointestinal (GI) problems; however, the associations among these symptoms in children with ASD have not been previously examined. The current study examined bivariate and multivariate relations among anxiety, sensory over-responsivity, and chronic GI problems in a sample of 2,973 children with ASD enrolled in the Autism Treatment Network (ages 2-17 years, 81.6 % male). Twenty-four percent of the sample experienced at least one type of chronic GI problem (constipation, abdominal pain, bloating, diarrhea, and/or nausea lasting three or more months). Children with each type of GI problem had significantly higher rates of both anxiety and sensory over-responsivity. Sensory over-responsivity and anxiety were highly associated, and each provided unique contributions to the prediction of chronic GI problems in logistic regression analyses. The results indicate that anxiety, sensory over-responsivity and GI problems are possibly interrelated phenomenon for children with ASD, and may have common underlying mechanisms.
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“Furthermore, a generalized increase in the stress response is also characteristic of those with ASD relative to typically-developing individuals (Ming et al., 2005; Mazurek et al., 2013; Spratt et al., 2012).”
From Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder (2016) · cites this paper as Mazurek et al., 2013
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“Anxiety has been highly associated with chronic GI problems in children with ASD 32.”
From Gastrointestinal Issues and Autism Spectrum Disorder (2020) · cites this paper as [32]
Citations
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Nutritional characteristics of children with autism spectrum disorder
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Metadata
- Authors
- Mazurek, M. O., Vasa, R. A., Kalb, L. G., Kanne, S. M., Rosenberg, D., Keefer, A., Murray, D. S., Freedman, B., & Lowery, L. A.
- Affiliations
- University of Missouri (US)
- Kennedy Krieger Institute (US)
- Baylor College of Medicine (US)
- Emmes (United States) (US)
- Cincinnati Children's Hospital Medical Center (US)
- University of Delaware (US)
- Corresponding author
- Mazurek, Micah O.
- ORCID
- Venue
- Journal of Abnormal Child Psychology
- Published
- 2012-08-01
- Volume
- 41
- Issue
- 1
- Pages
- 165-176
- ISSN
- 0091-0627 (ISSN-L)
- 1573-2835
- OpenAlex
- W2035020487
- Cited by
- 419
- References
- 87
- Citations by year
- 2026: 26 · 2025: 18 · 2024: 46 · 2023: 28 · 2022: 33 · 2021: 38 · 2020: 55 · 2019: 28 · 2018: 26 · 2017: 29 · 2016: 33 · 2015: 20 · 2014: 22 · 2013: 16
- FWCI
- 9.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Research on Child and Adolescent Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Autism Speaks
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- autism spectrum disorder, anxiety, sensory hypersensitivity, gastrointestinal problems, chronic constipation, abdominal pain, bloating, diarrhea, nausea, children, comorbidities
- MeSH terms
- Adolescent, Anxiety, Child, Child Development Disorders, Pervasive, Child, Preschool, Chronic Disease, Constipation, Diarrhea, Female, Gastrointestinal Diseases, Humans, Male, Regression Analysis, Sensation Disorders, Abdominal Pain, Multivariate Analysis
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