Pressurized liquids as an alternative green process to extract antiviral agents from the edible seaweed Himanthalia elongata

Algae are a good source of dietary fibers because of non-digestible polysaccharides in the algal cell wall, which possess antioxidant, hypoglycemic, antiviral, antitumor, and anti-inflammatory activities due to fucoidan and laminarin.

“Algae are considered as a good source of dietary fibers because of the presence of non-digestible polysaccharides in the algal cell wall (Figure 3) [11]. It has been shown that they possess activities, like antioxidant [12], hypoglycemic [13], antiviral [14,15], antitumor [16], and anti-inflammatory due to the presence of fucoidan and laminarin [17].”

According to published studies, SWE is the most promising technique for extraction of bioactive compounds.

“According to published studies [14,31,36], this is the most promising technique for the extraction of bioactive compounds.”

Extracts and bioactive compounds from SWE have shown bioactivity such as antioxidant, antiviral, antimicrobial, and anti-hyaluronidase activity.

“The extracts and bioactive compounds have shown bioactivity such as antioxidant, antiviral, antimicrobial and anti-hyaluronidase activity [14,34,58,59].”

The polysaccharide compounds in SWE extracts exhibited antiviral activity when the extracts were added previously to virus or simultaneously with virus.

“These compounds exhibited antiviral activity when the extracts were added previously to virus or simultaneously with virus.”

SWE extracts against Herpes simplex virus type 1 consist mostly of polysaccharides.

“After that, the extracts were analyzed by GC-MS, and it was shown that they consist mostly of polysaccharides.”