CoChat
Sign Up
Cited by 11

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The synthesis and characterization of glutathione-modified superparamagnetic iron oxide nanoparticles and their distribution in rat brains after injection in substantia nigra

Han, Guihua, Zhang, Baolin, Zhang, Hao, Han, Dong, Tan, Jie, Yang, Boning·2019·Journal of Materials Science: Materials in Medicine
DOI 10.1007/s10856-018-6209-3
Open this paper in CoChat — free account

Abstract

Glutathione-modified superparamagnetic iron oxide nanoparticles (GSH-SPIONs) were prepared by conjugating glutathione (GSH) on the surface of the PEG (Polyethylene glycol)/PEI (polyethyleneimine)-SPIONs which were synthesized by thermal decomposition method. Thermogravimetric analysis showed that the mass fraction of GSH on the surface of SPIONs was 30.64 wt%. GSH-SPIONs in PBS were injected into the substantia nigra of rat brains. The subcellular distributions of the nanoparticles in the brains was examined by the transmission electron microscope (TEM). A remarkable amount of GSH-SPIONs were found in vesicles inside cell bodies and axons, and in mitochondria. TEM pictures show that GSH-SPIONs enter the neuronal cells by endocytosis and travel through axoplasmic transport. GSH-SPIONs have great potential as drug delivery agents in the brain to treat diseases or study brain function via mitochondria-targeting way or axoplasmic transport way.

Overview

Integrity signals

Registry

Crossref · 10.1007/s10856-018-6209-3

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 43

  1. Abbasi Pour S, Shaterian HR. Design and characterization of lisinopril-loaded superparamagnetic nanoparticles as a new contrast agent for in vitro, in vivo MRI imaging, diagnose the tumors and drug delivery system. J Mater Sci Mater Med. 2017;28:91. · DOI
  2. Islam MS, Haque P, Rashid TU, Khan MN, Mallik AK, Khan MN, et al. Core-shell drug carrier from folate conjugated chitosan obtained from prawn shell for targeted doxorubicin delivery. J Mater Sci Mater Med. 2017;28:55. · DOI
  3. Huang Y, Mao K, Zhang B, Zhao Y. Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics. Mater Sci Eng C Mater Biol Appl. 2017;70:763–71. · DOI
  4. Lee CM, Jeong HJ, Kim SL, Kim EM, Kim DW, Lim ST, et al. SPION-loaded chitosan-linoleic acid nanoparticles to target hepatocytes. Int J Pharm. 2009;371:163–9. · DOI
  5. Xiong F, Huang S, Gu N. Magnetic nanoparticles: recent developments in drug delivery system. Drug Dev Ind Pharm. 2018;44:697–706. · DOI
  6. Xu HL, Mao KL, Huang YP, Yang JJ, Xu J, Chen PP, et al. Glioma-targeted superparamagnetic iron oxide nanoparticles as drug-carrying vehicles for theranostic effects. Nanoscale. 2016;8:14222–36. · DOI
  7. Hudson R. Coupling the magnetic and heat dissipative properties of Fe3O4 particles to enable applications in catalysis, drug delivery, tissue destruction and remote biological interfacing. RSC Adv. 2016;6:4262–70. · DOI
  8. Xie J, Gu N, Zhang Y. Controlled synthesis and surface modification of magnetic nanoparticles with high performance for cancer theranostics combining targeted MR imaging and hyperthermia. In: Dai Z, editor. Advances in nanotheranostics II: cancer theranostic nanomedicine. Singapore: Springer Singapore; 2016, 39–73. · DOI
  9. Lachowicz D, Szpak A, Malek-Zietek KE, Kepczynski M, Muller RN, Laurent S, et al. Biocompatible and fluorescent superparamagnetic iron oxide nanoparticles with superior magnetic properties coated with charged polysaccharide derivatives. Colloids Surf B Biointerfaces. 2017;150:402–7. · DOI
  10. Luchini A, Heenan RK, Paduano L, Vitiello G. Functionalized SPIONs: the surfactant nature modulates the self-assembly and cluster formation. Phys Chem Chem Phys. 2016;18:18441–9. · DOI
  11. Luchini A, Vitiello G, Rossi F, Ruiz De Ballesteros O, Radulescu A, D’Errico G, et al. Developing functionalized Fe3O4-Au nanoparticles: a physico-chemical insight. Phys Chem Chem Phys. 2015;17:6087–97. · DOI
  12. Chen R, Romero G, Christiansen MG, Mohr A, Anikeeva P. Wireless magnetothermal deep brain stimulation. Science. 2015;347:1477–80. · DOI
  13. Stanley SA, Gagner JE, Damanpour S, Yoshida M, Dordick JS, Friedman JM. Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science. 2012;336:604–8. · DOI
  14. Liu Y, Li J, Xu K, Gu J, Huang L, Zhang L et al. Characterization of superparamagnetic iron oxide nanoparticle-induced apoptosis in PC12 cells and mouse hippocampus and striatum. Toxicol Lett. 2018;292:151–61. · DOI
  15. Luchini A, Gerelli Y, Fragneto G, Nylander T, Palsson GK, Appavou MS, et al. Neutron Reflectometry reveals the interaction between functionalized SPIONs and the surface of lipid bilayers. Colloids Surf B Biointerfaces. 2017;151:76–87. · DOI
  16. Zhao F, Zhao Y, Liu Y, Chang X, Chen C, Zhao Y. Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small. 2011;7:1322–37. · DOI
  17. Santos MC, Seabra AB, Pelegrino MT, Haddad PS. Synthesis, characterization and cytotoxicity of glutathione- and PEG-glutathione-superparamagnetic iron oxide nanoparticles for nitric oxide delivery. Appl Surf Sci. 2016;367:26–35. · DOI
  18. Rahantaniaina MS, Li S, Chatel-Innocenti G, Tuzet A, Mhamdi A, Vanacker H, et al. Glutathione oxidation in response to intracellular H2O2: key but overlapping roles for dehydroascorbate reductases. Plant Signal Behav. 2017;12:e1356531. · DOI
  19. He C, Jiang S, Jin H, Chen S, Lin G, Yao H, et al. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity. Biomaterials. 2016;83:102–14. · DOI
  20. Yu M, Zhou C, Liu J, Hankins JD, Zheng J. Luminescent gold nanoparticles with pH-dependent membrane adsorption. J Am Chem Soc. 2011;133:11014–7. · DOI
  21. Vinluan RD 3rd, Liu J, Zhou C, Yu M, Yang S, Kumar A, et al. Glutathione-coated luminescent gold nanoparticles: a surface ligand for minimizing serum protein adsorption. ACS Appl Mater Interfaces. 2014;6:11829–33. · DOI
  22. Yoffe S, Leshuk T, Everett P, Gu F. Superparamagnetic iron oxide nanoparticles (SPIONs): synthesis and surface modification techniques for use with MRI and other biomedical applications. Curr Pharm Des. 2013;19:493–509. · DOI
  23. Zhang Y, Kohler N, Zhang M. Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake. Biomaterials. 2002;23:1553–61. · DOI
  24. Muthiah M, Park IK, Cho CS. Surface modification of iron oxide nanoparticles by biocompatible polymers for tissue imaging and targeting. Biotechnol Adv. 2013;31:1224–36. · DOI
  25. Zhao F, Zhang B, Feng L. Preparation and magnetic properties of magnetite nanoparticles. Mater Lett. 2012;68:112–4. · DOI
  26. Gogoi M, Deb P, Vasan G, Keil P, Kostka A, Erbe A. Direct monophasic replacement of fatty acid by DMSA on SPION surface. Appl Surf Sci. 2012;258:9685–91. · DOI
  27. Xu P, Shen Z, Zhang B, Wang J, Wu R. Synthesis and characterization of superparamagnetic iron oxide nanoparticles as calcium-responsive MRI contrast agents. Appl Surf Sci. 2016;389:560–6. · DOI
  28. Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol. 2004;16:437–45. · DOI · Paper page
  29. Brown A. Axonal transport of membranous and nonmembranous cargoes: a unified perspective. J Cell Biol. 2003;160:817–21. · DOI
  30. Xu S, Olenyuk BZ, Okamoto CT, Hamm-Alvarez SF. Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances. Adv Drug Deliv Rev. 2013;65:121–38. · DOI
  31. Su L, Zhang B, Huang Y, Zhang H, Xu Q, Tan J. Superparamagnetic iron oxide nanoparticles modified with dimyristoylphosphatidylcholine and their distribution in the brain after injection in the rat substantia nigra. Mater Sci Eng C Mater Biol Appl. 2017;81:400–6. · DOI
  32. Su L, Zhang B, Huang Y, Fan Z, Zhao Y. Enhanced cellular uptake of iron oxide nanoparticles modified with 1,2-dimyristoyl-sn-glycero-3-phosphocholine. RSC Adv. 2017;7:38001–7. · DOI
  33. Kim Y-K, Zhang M, Lu J-J, Xu F, Chen B-A, Xing L, et al. PK11195-chitosan-graft-polyethylenimine-modified SPION as a mitochondria-targeting gene carrier. J Drug Target. 2016;24:457–67. · DOI
  34. Chakraborty A, Jana NR. Design and synthesis of triphenylphosphonium functionalized nanoparticle probe for mitochondria targeting and imaging. J Phys Chem C. 2015;119:2888–95. · DOI
  35. Ghasemi A, Jafari S, saeidi J, Mohtashami M, Salehi I. Synthesis and characterization of polyglycerol coated superparamagnetic iron oxide nanoparticles and cytotoxicity evaluation on normal human cell lines. Colloids Surf A Physicochem Eng Asp. 2018;551:128–36. · DOI
  36. Milane L, Trivedi M, Singh A, Talekar M, Amiji M. Mitochondrial biology, targets, and drug delivery. J Control Release. 2015;207:40–58. · DOI
  37. Wang B, Feng WY, Wang M, Shi JW, Zhang F, Ouyang H, et al. Transport of intranasally instilled fine Fe2O3 particles into the brain: micro-distribution, chemical states, and histopathological observation. Biol Trace Elem Res. 2007;118:233–43. · DOI
  38. Lasek RJ, Garner JA, Brady ST. Axonal transport of the cytoplasmic matrix. J Cell Biol. 1984;99:212–21. · DOI
  39. Jinlu Z, Qing C, Junpeng Z, Mingfu L, Yilin S, Bing W, et al. Ultrastructure of the nervous system. 1st edn. Beijing. 2011; Peking Union Medical College Press.
  40. Davis BM, Tian K, Pahlitzsch M, Brenton J, Ravindran N, Butt G, et al. Topical Coenzyme Q10 demonstrates mitochondrial-mediated neuroprotection in a rodent model of ocular hypertension. Mitochondrion. 2017;36:114–23. · DOI
  41. Li WQ, Wang Z, Hao S, He H, Wan Y, Zhu C, et al. Mitochondria-targeting polydopamine nanoparticles to deliver doxorubicin for overcoming drug resistance. ACS Appl Mater Interfaces. 2017;9:16793–802. · DOI
  42. Castle MJ, Gershenson ZT, Giles AR, Holzbaur EL, Wolfe JH. Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport. Hum Gene Ther. 2014;25:705–20. · DOI
  43. Salegio EA, Streeter H, Dube N, Hadaczek P, Samaranch L, Kells AP, et al. Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy. Front Neuroanat. 2014;8:9. · DOI

Cited by

Sorted by citations

See all 11

Metadata

Authors
Han, G., Zhang, B., Zhang, H., Han, D., Tan, J., & Yang, B.
ORCID
Zhang, Baolin
Venue
Journal of Materials Science: Materials in Medicine
Publisher
Springer Science and Business Media LLC
Published
2018-12-19
Volume
30
Issue
1
ISSN
  • 0957-4530
  • 1573-4838
DOI
10.1007/s10856-018-6209-3
Cited by
11
References
2
Language
en
Licence
www.springer.com/tdm (tdm)
Funders
the National Natural Science Foundation of China (51562007)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review