Cited by 148EEG and Brain-Computer InterfacesEmotion and Mood RecognitionTreatment of Major Depression

Classification of depression patients and normal subjects based on electroencephalogram (EEG) signal using alpha power and theta asymmetry

Mahato, Shalini, Paul, Sanchita·2020·Journal of Medical Systems

Abstract

Depression or Major Depressive Disorder (MDD) is a mental illness which negatively affects how a person thinks, acts or feels. MDD has become a major disease affecting millions of people presently. The diagnosis of depression is questionnaire based and is not based on any objective criteria. In this paper, feature extracted from EEG signal are used for the diagnosis of depression. Alpha, alpha1, alpha2, beta, delta and theta power and theta asymmetry was used as feature. Alpha1, alpha2 along with theta asymmetry was also used as a feature. Multi-Cluster Feature Selection (MCFS) was used for feature selection when feature combination was used. The classifiers used were Support Vector Machine (SVM), Logistic Regression (LR), Naïve-Bayesian (NB) and Decision Tree (DT). Alpha2 showed higher classification accuracy than alpha1 and alpha power in all applied classifier. From t-test it was found that there was a significant difference in the theta power of left and right hemisphere of normal subjects, but there was no significant difference in depression patients. Average theta asymmetry in normal subjects is higher than MDD patients but the difference in theta asymmetry in normal subjects and MDD patients is not significant. The combination of alpha2 and theta asymmetry showed the highest classification accuracy of 88.33% in SVM.

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Crossref · 10.1007/s10916-019-1486-z

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  • Asymmetries in the alpha2 and theta bands, particularly when analyzed with a Support Vector Machine (SVM), achieved an accuracy rate of 88.33% for depression diagnosis.

    “Notably, findings suggest that asymmetries in the alpha2 and theta bands, particularly when analyzed with a Support Vector Machine (SVM), lead to higher diagnostic precision, with an accuracy rate of 88.33%.”

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Authors
Mahato, S., & Paul, S.
Affiliations
Birla Institute of Technology, Mesra (IN)
Corresponding author
Mahato, Shalini
Venue
Journal of Medical Systems
Published
2019-12-13
Volume
44
Issue
1
Pages
28-28
ISSN
  • 0148-5598 (ISSN-L)
  • 1573-689X
OpenAlex
W2996393987
Cited by
148
References
28
Citations by year
2026: 19 · 2025: 25 · 2024: 24 · 2023: 30 · 2022: 25 · 2021: 17 · 2020: 8
FWCI
7.27
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Medical Systems (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Emotion and Mood Recognition
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
major depressive disorder, depression diagnosis, EEG features, alpha power, theta power, feature selection, support vector machine, brain asymmetry
MeSH terms
Adult, Bayes Theorem, Depressive Disorder, Major, Major Depressive Disorder, Electroencephalography, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Logistic Models, Support Vector Machine

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