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Role of thermal history on the thermal behavior of poly(L-lactic acid) studied by DSC and optical microscopy
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The high-temperature exothermic peak observed before the main melting peak in PLLA has been attributed to recrystallization or to the formation of a more stable crystalline phase.
“The one at high temperatures has been previously observed for PLLA homopolymers of different molecular weights during heating scans and has been attributed to recrystallization 49 -51 or to the formation of a more stable crystalline phase; see below. 14,52 -57”
From Crystallization Kinetics and Morphology of Biodegradable Double Crystalline PLLA- b -PCL Diblock Copolymers (2010) · cites this paper as [50]
The higher the crystallization rates, the more likely small and imperfect crystals change successively into more stable crystals through a melt-recrystallization mechanism or by a phase transition, giving rise to the exothermic signal before the melting peak.
“The higher the crystallization rates, the more likely it will be for small and imperfect crystals to change successively into more stable crystals through a melt-recrystallization mechanism or by a phase transition, giving rise to the exothermic signal before the melting peak. 49,50”
From Crystallization Kinetics and Morphology of Biodegradable Double Crystalline PLLA- b -PCL Diblock Copolymers (2010) · cites this paper as [50]
The appearance and intensity of the small exotherm observed before the main melting peak depend on cooling and heating rates.
“Theappearance and intensity of the small exotherm observed before the main melting peak have been reported as being dependent on cooling and heating rates. 49,50”
From Crystallization Kinetics and Morphology of Biodegradable Double Crystalline PLLA- b -PCL Diblock Copolymers (2010) · cites this paper as [50]
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Castillo, R. V., Müller, A. J., Raquez, J.-M., & Dubois, P. (2010) · Macromolecules · doi:10.1021/ma100201g · Cited by 175
Influence of melting conditions on the thermal behaviour of poly(l-lactic acid)
Wang, Y., & Mano, J. F. (2005) · European Polymer Journal · doi:10.1016/j.eurpolymj.2005.04.030 · Cited by 113
Self-citationMartino, V. P., Ruseckaite, R. A., & Jiménez, A. (2006) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-006-7897-3 · Cited by 103
Crosslinked blends of poly(lactic acid) and polyacrylates: AFM, DSC and XRD studies
Kaczmarek, H., Nowicki, M., Vuković‐Kwiatkowska, I., & Nowakowska, S. K. (2013) · Journal of Polymer Research · doi:10.1007/s10965-013-0091-y · Cited by 84
“PLA is a semicrystalline polymer, which means that both phases: amorphous and ordered exist together but the crystallinity degree depends strongly on the conditions of sample preparation [14, 15].”
BackgroundResultEpoxidized soybean oil‐plasticized poly(lactic acid) films performance as impacted by storage
Xing, C., & Matuana, L. M. (2015) · Journal of Applied Polymer Science · doi:10.1002/app.43201 · Cited by 60
Malmgren, T., Mays, J., & Pyda, M. (2006) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-005-7066-0 · Cited by 61
Thermal analysis of the multiple melting behavior of poly(butylene succinate‐co‐adipate)
Wang, Y., Bhattacharya, M., & Mano, J. F. (2005) · Journal of Polymer Science Part B Polymer Physics · doi:10.1002/polb.20589 · Cited by 56
Self-citationSong, P., Chen, G., Wei, Z., Zhang, W., & Liang, J. (2012) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-012-2502-4 · Cited by 38
Dobreva, T., Pereña, J., Perez, E., Benavente, R., & Garcia, M. (2010) · Polymer Composites · doi:10.1002/pc.20882 · Cited by 30
Effect of nanosilver on the photodegradation of poly(lactic acid)
Mucha, M., Białas, S., & Kaczmarek, H. (2013) · Journal of Applied Polymer Science · doi:10.1002/app.40144 · Cited by 33
Carmagnola, I., Nardo, T., Gentile, P., Tonda‐Turo, C., Mattu, C., Cabodi, S., Defilippi, P., & Chiono, V. (2014) · International Journal of Polymeric Materials · doi:10.1080/00914037.2014.886247 · Cited by 32
Drumond, W. S., Mothé, C. G., & Wang, S. H. (2006) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-005-7341-0 · Cited by 22
Wongrakpanich, A., Khunkitchai, N., Achayawat, Y., & Suksiriworapong, J. (2023) · Polymers · doi:10.3390/polym15020266 · Cited by 20
“Interestingly, all of the ketorolac-loaded PLA-containing microparticles had double cold crystallization and melting events, suggesting that the encapsulation of the drug interfered with the cold crystallization of the polymer, leading to heterogeneous and homogeneous nucleation [34,35].”
BackgroundPLLA‐HA vs. PLGA‐HA characterization and comparative analysis
Albano, C., González, G., Palacios, J. K., Karam, A. R., & Covis, M. (2013) · Polymer Composites · doi:10.1002/pc.22445 · Cited by 17
Isothermal crystallization kinetics and melting behavior of PLLA/f-MWNTs composites
Shi, J., Xiu-ping, L., Li, H., & Li, D. (2014) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-014-3885-1 · Cited by 17
“These distinct melting behaviors are analogous with some earlier reports for melt-crystallized PLLA with a slight difference in temperature range [49, 50].”
Salgado, A. J., Wang, Y., Mano, J. F., & Reis, R. L. (2006) · Materials science forum · doi:10.4028/www.scientific.net/msf.514-516.1020 · Cited by 16
Self-citationMultiple melting behaviour of poly(l-lactide-co-glycolide) investigated by DSC
Wang, Y., & Mano, J. F. (2009) · Polymer Testing · doi:10.1016/j.polymertesting.2009.03.006 · Cited by 14
Self-citationEffect of in situ reaction on thermal and mechanical properties of polylactide/talc composites
Hong, Y., Chen, L., Song, G., Bassir, D., Cheng, S., Shi, X., Liu, H., & Tang, G. (2017) · Polymer Composites · doi:10.1002/pc.24530 · Cited by 13
Influence of Thermal Treatment on the Thermal Behavior of Poly‐ L ‐lactide
Zhou, Z. (2007) · Journal of Macromolecular Science Part B · doi:10.1080/00222340701629364 · Cited by 8
“In addition to crystallization from the melt, PLLA may crystallize from the glassy state.([11]) The cold crystallization of PLLA has not been appropriately addressed,”
BackgroundResultLuo, J., Huo, F., Lin, H. M., Lin, Z., Chen, Z., Fang, Y., Jiang, H., Wang, H., Tu, K., Liu, D., et al. (2012) · Journal of Polymer Science Part B Polymer Physics · doi:10.1002/polb.23127 · Cited by 6
Palacios, J. K., Albano, C., González, G., Castillo, R. V., Karam, A. R., & Covis, M. (2014) · Polymer Engineering and Science · doi:10.1002/pen.23936 · Cited by 5
On the enthalpy of melting of poly(l-lactide)
Suljovrujić, E., & Miličević, D. (2019) · IJPAC. International journal of polymer analysis and characterization · doi:10.1080/1023666x.2019.1598635 · Cited by 4
Albano, C., González, G., Palacios, J. K., Karam, A. R., Castillo, R. V., & Covis, M. (2013) · Revista de la Facultad de Ingeniería Universidad Central de Venezuela · Cited by 5
Nasser, F. T., Elsissy, A. R., & Farouk, W. M. (2025) · The International Journal of Advanced Manufacturing Technology · doi:10.1007/s00170-025-16369-y · Cited by 4
“This can lead to two competing crystallization mechanisms during heating: one initiated from existing nuclei and the other from spontaneous nucleation within the amorphous matrix [66].”
Comparison of Photochemical and Thermal Degradation of Poly (Lactic Acid) Doped by Nanosilver
Mucha, M., & Książek, S. (2015) · Journal of Chemistry and Chemical Engineering · doi:10.17265/1934-7375/2015.01.003 · Cited by 4
Sensing the melting transition of semicrystalline polymers via a novel fluorescence technique
Nile, R. G., Rajput, H., Sims, C., & Jin, K. (2021) · Polymer · doi:10.1016/j.polymer.2021.124070 · Cited by 4
Characterization and phase transformation study of TlSbSe2 crystals
Chrissafis, K., Özer, M., Vinga, E. S., Polychroniadis, E. K., Chatzistavrou, X., & Paraskevopoulos, K. M. (2006) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-005-7213-7 · Cited by 3
Miličević, D. S., & Suljovrujić, E. H. (2017) · Polymer International · doi:10.1002/pi.5382 · Cited by 2
Su, Y., Wu, B., Wang, C., Zhou, J., Sun, H., Cao, W., & Yu, H. (2026) · Journal of Applied Physics · doi:10.1063/5.0316676 · Cited by 1
Avaliação dos efeitos da radiação ionizante em compósitos de PCL/PLLA com fibra de coco
Kodama, Y. (2011) · doi:10.11606/t.85.2011.tde-30062011-161356 · Cited by 1
Shih, T.-C., Lin, C.-T., Lee, S., Chang, W., Teng, N., Ou, K., & Tseng, H. (2013) · Biomedical Engineering Applications Basis and Communications · doi:10.4015/s1016237213400036
Nongyai, N., Intranuwong, J., Shin, S. K., Kim, M., & Kwon, Y. K. (2025) · Journal of Polymers and the Environment · doi:10.1007/s10924-025-03678-2
“Moreover, the observed decrease in melting tem - perature in the DSC thermograms (not shown here) further supports the chain confinement effect that disrupts the regu - lar crystalline packing of PVL and PCL within the triblock structure [ 29, 30 ].”
Nouri, M., Belhabib, S., Tahlaiti, M., Vijayakumar, J., Boller, E., & Guessasma, S. (2026) · Polymers · doi:10.3390/polym18070836
“In addition, Wang and Mano [40] observed that the endothermic peak corresponding to PLA melting does https://doi.org/10.3390/polym18070836 not appear at heating rates below 40 ◦ C/min.”
Influential
Metadata
- Authors
- Wang, Y., & Mano, J. F.
- Affiliations
- 3B's Research Group (PT)
- University of Minho (PT)
- ORCID
- Venue
- Journal of Thermal Analysis and Calorimetry
- Published
- 2005-03
- Volume
- 80
- Issue
- 1
- Pages
- 171-175
- ISSN
- 1388-6150 (ISSN-L)
- 1572-8943
- OpenAlex
- W2028999056
- Cited by
- 33
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 1 · 2021: 1 · 2019: 1 · 2017: 2 · 2015: 2 · 2014: 3 · 2013: 5 · 2012: 2
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Thermal Analysis and Calorimetry (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer crystallization and properties
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Materials Science › Materials Chemistry › Thermal and Kinetic Analysis
- Keywords
- poly(L-lactic acid), thermal history, cold crystallization, melting behavior, amorphous polymers, metastable phases, melt recrystallization, heating rate effects, polymer crystallization
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