Regulatory role of membrane fluidity in gene expression and physiological functions

Los, Dmitry A.; Mironov, Kirill S.; Allakhverdiev, Suleyman I.

doi:10.1007/s11120-013-9823-4

Cited by 254Photosynthetic Processes and MechanismsLipid Membrane Structure and BehaviorLipid metabolism and biosynthesis

Regulatory role of membrane fluidity in gene expression and physiological functions

Los, Dmitry A., Mironov, Kirill S., Allakhverdiev, Suleyman I.·2013·Photosynthesis Research

DOI 10.1007/s11120-013-9823-4

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Abstract

Plants, algae, and photosynthetic bacteria experience frequent changes in environment. The ability to survive depends on their capacity to acclimate to such changes. In particular, fluctuations in temperature affect the fluidity of cytoplasmic and thylakoid membranes. The molecular mechanisms responsible for the perception of changes in membrane fluidity have not been fully characterized. However, the understanding of the functions of the individual genes for fatty acid desaturases in cyanobacteria and plants led to the directed mutagenesis of such genes that altered the membrane fluidity of cytoplasmic and thylakoid membranes. Characterization of the photosynthetic properties of the transformed cyanobacteria and higher plants revealed that lipid unsaturation is essential for protection of the photosynthetic machinery against environmental stresses, such as strong light, salt stress, and high and low temperatures. The unsaturation of fatty acids enhances the repair of the damaged photosystem II complex under stress conditions. In this review, we summarize the knowledge on the mechanisms that regulate membrane fluidity, on putative sensors that perceive changes in membrane fluidity, on genes that are involved in acclimation to new sets of environmental conditions, and on the influence of membrane properties on photosynthetic functions.

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A decrease in the culture temperature leads to the shift of desaturases activity and an increase in the unsaturation level in fatty acids, which ensure the cell membrane fluidity under temperature stress conditions.
“Besides, a decrease in the culture temperature leads to the shift of desaturases activity and an increase in the unsaturation level in FAs, which ensure the cell membrane fluidity under temperature stress conditions [155–158].”
From Microalgae biofuels: illuminating the path to a sustainable future amidst challenges and opportunities (2024) · cites this paper as [158]
The molecular motion of cyanobacterial glycerolipids is mostly determined by the degree of unsaturation of the fatty acids esterified to the glycerol backbones.
“The molecular motion of these glycerolipids is mostly determined by the degree of unsaturation of the fatty acids esterified to the glycerol backbones [42].”
From Spirulina/Arthrospira/Limnospira—Three Names of the Single Organism (2024) · cites this paper as [42]

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“Besides, a decrease in the culture temperature leads to the shift of desaturases activity and an increase in the unsaturation level in FAs, which ensure the cell membrane fluidity under temperature stress conditions [155–158].”
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“The molecular motion of these glycerolipids is mostly determined by the degree of unsaturation of the fatty acids esterified to the glycerol backbones [42].”
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�ber die Dreidimensionale gestaltung des Thylakoidsystems in den Chloroplasten
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Authors: Los, D. A., Mironov, K. S., & Allakhverdiev, S. I.
Affiliations: Russian Academy of Sciences (RU)
Corresponding author: Los, Dmitry A.
ORCID: Los, Dmitry A.
Mironov, Kirill S.
Allakhverdiev, Suleyman I.
Venue: Photosynthesis Research
Publisher: Springer Science and Business Media LLC
Published: 2013-04-20
Volume: 116
Issue: 2-3
Pages: 489-509
ISSN: 0166-8595 (ISSN-L)
1573-5079
DOI: 10.1007/s11120-013-9823-4
OpenAlex: W1980155153
Cited by: 254
References: 150
Citations by year: 2026: 9 · 2025: 16 · 2024: 33 · 2023: 21 · 2022: 17 · 2021: 32 · 2020: 23 · 2019: 15 · 2018: 15 · 2017: 22 · 2016: 16 · 2015: 20 · 2014: 14 · 2013: 1
FWCI: 1.60
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Photosynthesis Research (publishedVersion)
PubMed (publishedVersion)
Funders: Russian Foundation for Basic Research
Russian Science Foundation
Russian Academy of Sciences
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Keywords: membrane fluidity, lipid unsaturation, fatty acid desaturase, thylakoid membranes, plasma membrane, photosynthetic acclimation, temperature stress, light stress, salt stress, photosystem II repair, cyanobacteria, plants, algae, gene expression regulation
MeSH terms: Fatty Acids, Membrane Fluidity, Membrane Lipids, Plants, Temperature, Gene Expression Regulation, Plant

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Regulatory role of membrane fluidity in gene expression and physiological functions

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