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Guidance for the prevention and treatment of cancer-associated venous thromboembolism
Open accessAbstract
Venous thromboembolism (VTE) is a highly prevalent complication of malignancy with emerging changes in incidence, diagnosis and treatment paradigms. This manuscript, initiated by the Anticoagulation Forum, provides clinical guidance based on existing guidelines and consensus expert opinion where guidelines are lacking. We address a) the appropriate workup to search for occult malignancy in patients with idiopathic VTE, b) identification of high-risk cancer patients for primary thromboprophylaxis, c) the appropriate immediate and long-term treatment for people with cancer diagnosed with acute thromboembolism, d) the appropriate duration of anticoagulation and e) the appropriate treatment strategy in patients with recurrent VTE on anticoagulation. Areas of controversy and future directions in this field are highlighted.
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Cited by
Arterial thromboembolic events preceding the diagnosis of cancer in older persons
Navi, B. B., Reiner, A. S., Kamel, H., Iadecola, C., Okin, P. M., Tagawa, S. T., Panageas, K. S., & DeAngelis, L. M. (2019) · Blood · doi:10.1182/blood-2018-06-860874 · Cited by 179
How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy
Schulman, S. (2017) · Blood · doi:10.1182/blood-2017-03-742304 · Cited by 62
Platelets in aging and cancer—“double-edged sword”
Faria, A. V. S., Andrade, S. S., Peppelenbosch, M. P., Ferreira-Halder, C. V., & Fuhler, G. M. (2020) · Cancer and Metastasis Reviews · doi:10.1007/s10555-020-09926-2 · Cited by 38
Zarrouk, M., Salim, S., Elf, J., Gottsäter, A., & Acosta, S. (2017) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2016.11.002 · Cited by 35
Metadata
- Authors
- Khorana, A. A., Carrier, M., Garcia, D. A., & Lee, A. Y. Y.
- Venue
- Journal of Thrombosis and Thrombolysis
- Published
- 2016-01
- Volume
- 41
- Issue
- 1
- Pages
- 81-91
- ISSN
- 0929-5305 (ISSN-L)
- 1573-742X
- OpenAlex
- W2259176485
- Cited by
- 210
- References
- 0
- FWCI
- 33.80
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Khorana, A. A., Carrier, M., Garcia, D. A., & Lee, A. Y. Y. (2016). Guidance for the prevention and treatment of cancer-associated venous thromboembolism. Journal of Thrombosis and Thrombolysis. https://doi.org/10.1007/s11239-015-1313-4
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