Increased urinary 8-hydroxy-2′-deoxyguanosine levels in workers exposed to di-(2-ethylhexyl) phthalate in a waste plastic recycling site in China
Abstract
Background Di-(2-ethylhexyl) phthalate (DEHP) is a common plasticizer used in industrial and diverse consumer products. Animal studies indicate DEHP caused developmental, reproductive, and hepatic toxicities. However, human studies of the potential effects of DEHP are limited.Methods The exposed site with a history of over 20 years of waste plastic recycling was located in Hunan Province, China. The reference site without known DEHP pollution source was about 50 km far away from the exposed site. In this study, 181 workers working in plastic waste recycling and 160 gender-age matched farmers were recruited. DEHP concentrations in water and cultivated soil samples, serum thyroid-stimulating hormone, malondialdehyde (MDA), superoxide dismutase (SOD), urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), and micronuclei frequency in human capillary blood lymphocytes were analyzed.Results Mean levels of DEHP were greater in environment at the recycling site than at reference site (industry wastewater for the exposed: 42.43 μg/l; well water: 14.20 vs. 0.79 μg/l, pond water: 135.68 vs. 0.37 μg/l, cultivated soil: 13.07 vs. 0.81 mg/kg, p < 0.05 for all). The workers had higher median levels of MDA (3.80 vs. 3.14 nmol/ml) and urinary 8-OHdG (340.37 vs. 268.18 μmol/mol creatinine) and decreased SOD activities (112.15 vs. 123.82 U/ml) than the reference group (p < 0.01 for all). Multivariate analysis revealed that the history of working in waste plastic recycling was an independent risk factor for the increased urinary 8-OHdG levels in the male workers (p < 0.01).Conclusions The occupational DEHP exposure might contribute to oxidative deoxyribonucleic acid damage in the male workers.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Additional phthalates may be added in reprocessing recycled plastics as well as in a later stage of production, and these are generally not removed from recycling of household plastic waste.
“Additional phthalates may be added in reprocessing recycled plastics (Hahladakis et al., 2018) as well as in a later stage of production (e.g.labelling and gluing), which are generally not removed from recycling of household plastic waste (Wang et al., 2011).”
From Packaging design for the circular economy: A systematic review (2022) · cites this paper as Wang et al., 2011
Cites
Synthetic polymers in the marine environment: A rapidly increasing, long-term threat
Moore, C. J. (2008) · Environmental Research · doi:10.1016/j.envres.2008.07.025 · Cited by 2,130 · see citing works
Marnett, L. J. (2000) · Carcinogenesis · doi:10.1093/carcin/21.3.361 · Cited by 1,887 · see citing works
Phthalates: Toxicology and exposure
Heudorf, U., Mersch‐Sundermann, V., & Angerer, J. (2007) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2007.07.011 · Cited by 1,494 · see citing works
Nielsen, F., Mikkelsen, B. B., Nielsen, J. B., Andersen, H. R., & Grandjean, P. (1997) · Clinical Chemistry · doi:10.1093/clinchem/43.7.1209 · Cited by 1,017 · see citing works
Environmental chemicals and thyroid function
Boas, M., Feldt‐Rasmussen, U., Skakkebæk, N. E., & Main, K. M. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02128 · Cited by 514 · see citing works
Peroxisome proliferator activated receptor-alpha expression in human liver.
Palmer, C. N., Hsu, M. H., Griffin, K. J., Raucy, J. L., & Johnson, E. F. (1998) · PubMed · Cited by 448 · see citing works
Peroxisome Proliferator Activated Receptor-α Expression in Human Liver
Palmer, C. N. A., Hsu, M.-H., Griffin, K. J., Raucy, J. L., & Johnson, E. F. (1998) · Molecular Pharmacology · doi:10.1124/mol.53.1.14 · Cited by 416 · see citing works
Hauser, R. B., Meeker, J. D., Singh, N. P., Silva, M. J., RYAN, L. M., Duty, S., & Calafat, A. M. (2006) · Human Reproduction · doi:10.1093/humrep/del428 · Cited by 405 · see citing works
Olusi, S. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0802066 · Cited by 390 · see citing works
trans-Activation of PPARα and PPARγ by Structurally Diverse Environmental Chemicals
Maloney, E. K., & Waxman, D. J. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8809 · Cited by 375 · see citing works
Pan, G., Hanaoka, T., Yoshimura, M., Zhang, S., Wang, P., Tsukino, H., Inoue, K., Nakazawa, H., Tsugane, S., & Takahashi, K. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9016 · Cited by 353 · see citing works
Occurrence of phthalate esters in the environment of the Netherlands
Peijnenburg, W. J. G. M., & Struijś, J. (2005) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2005.07.023 · Cited by 334 · see citing works
Seitz, H. K., & Stickel, F. (2006) · Biological Chemistry · doi:10.1515/bc.2006.047 · Cited by 326 · see citing works
Modes of Action and Species-Specific Effects of Di-(2-ethylhexyl)Phthalate in the Liver
Rusyn, I., Peters, J. M., & Cunningham, M. L. (2006) · Critical Reviews in Toxicology · doi:10.1080/10408440600779065 · Cited by 302 · see citing works
Antioxidative enzyme activities in human erythrocytes
Andersen, H. R., Nielsen, J. B., Nielsen, F., & Grandjean, P. (1997) · Clinical Chemistry · doi:10.1093/clinchem/43.4.562 · Cited by 301 · see citing works
Di(2-ethylhexyl) Phthalate Metabolites May Alter Thyroid Hormone Levels in Men
Meeker, J. D., Calafat, A. M., & Hauser, R. B. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.9852 · Cited by 300 · see citing works
Xu, G., Li, F., & Wang, Q. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.01.001 · Cited by 278 · see citing works
Self-citationvan Wezel, A. P., van Vlaardingen, Posthumus, R., Gh, C., & Sijm, D. T. H. M. (2000) · Ecotoxicology and Environmental Safety · doi:10.1006/eesa.2000.1930 · Cited by 262 · see citing works
Piconi, L., Quagliaro, L., & Ceriello, A. (2003) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2003.177 · Cited by 255 · see citing works
Zeng, F., Cui, K., Xie, Z., Liu, M., Li, Y., Lin, Y., Zeng, Z., & Li, F. (2007) · Environment International · doi:10.1016/j.envint.2007.09.002 · Cited by 241 · see citing works
Hines, E. P., Calafat, A. M., Silva, M. J., Mendola, P., & Fenton, S. E. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.11610 · Cited by 232 · see citing works
Distribution of phthalate esters in urban soils of subtropical city, Guangzhou, China
Zeng, F., Cui, K., Xie, Z., Wu, L., Luo, D., Chen, L., Lin, Y., Liu, M., & Sun, G. (2008) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2008.09.029 · Cited by 228 · see citing works
Meeker, J. D., Calafat, A. M., & Hauser, R. B. (2009) · Journal of Andrology · doi:10.2164/jandrol.108.006403 · Cited by 228 · see citing works
Phthalates and Children’s Health
Sathyanarayana, S. (2008) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2007.11.001 · Cited by 211 · see citing works
Grande, S. W., Martino‐Andrade, A. J., Talsness, C. E., Grote, K., Golombiewski, A., Sterner‐Kock, A., & Chahoud, I. (2006) · Toxicology · doi:10.1016/j.tox.2006.10.005 · Cited by 209 · see citing works
Talsness, C. E. (2008) · Environmental Research · doi:10.1016/j.envres.2008.08.008 · Cited by 207 · see citing works
Distribution of Phthalic Acid Esters in Wuhan section of the Yangtze River, China
Wang, F., Xia, X., & Sha, Y. (2007) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2007.10.028 · Cited by 206 · see citing works
Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis
Reddy, J. K., & Rao, M. S. R. (1989) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(89)90198-x · Cited by 194 · see citing works
Phthalates and nonylphenols in profiles of differently dressed soils
Vikelsøe, J., Thomsen, M., & Carlsen, L. (2002) · The Science of The Total Environment · doi:10.1016/s0048-9697(02)00063-3 · Cited by 191 · see citing works
Oehlmann, J., Oetken, M., & Schulte‐Oehlmann, U. (2008) · Environmental Research · doi:10.1016/j.envres.2008.07.016 · Cited by 179 · see citing works
Role of PPARα in mediating the effects of phthalates and metabolites in the liver
Lapinskas, P. J., Brown, S. S., Leesnitzer, L. M., Blanchard, S. G., Swanson, C., Cattley, R. C., & Corton, J. C. (2004) · Toxicology · doi:10.1016/j.tox.2004.09.008 · Cited by 173 · see citing works
Yuan, J., Chen, L., Chen, D., Guo, H., Bi, X., Ju, Y., Jiang, P., Shi, J., Yu, Z., Yang, J., et al. (2008) · Environmental Science & Technology · doi:10.1021/es702295f · Cited by 172 · see citing works
Self-citationPhthalate Esters in Human Milk: Concentration Variations over a 6-Month Postpartum Time
Zhu, J., Phillips, S. P., Feng, Y., & Yang, X. (2006) · Environmental Science & Technology · doi:10.1021/es060356w · Cited by 155 · see citing works
Ito, Y., Yamanoshita, O., Asaeda, N., Tagawa, Y., Lee, C., Aoyama, T., Ichihara, G., Furuhashi, K., Kamijima, M., Gonzalez, F. J., et al. (2007) · Journal of Occupational Health · doi:10.1539/joh.49.172 · Cited by 141 · see citing works
Chauvigné, F., Menuet, A., Lesné, L., Chagnon, M., Chevrier, C., Regnier, J.-F., Angerer, J., & Jégou, B. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11870 · Cited by 123 · see citing works
Survey of phthalate pollution in arable soils in China
Hu, X., Wen, B., & Shan, X.-Q. (2003) · Journal of Environmental Monitoring · doi:10.1039/b304669a · Cited by 117 · see citing works
Urinary phthalate metabolites and semen quality: a review of a potential biomarker of susceptibility
Hauser, R. B. (2007) · International Journal of Andrology · doi:10.1111/j.1365-2605.2007.00844.x · Cited by 109 · see citing works
Seo, K. W., Kim, K., Kim, Y. J., Choi, J. Y., Lee, K., & Choi, K. S. (2003) · Food and Chemical Toxicology · doi:10.1016/j.fct.2003.08.010 · Cited by 106 · see citing works
HASHIZUME, K., Nanya, J., Toda, C., Yasui, T., Nagano, H., & Kojima, N. (2002) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.25.209 · Cited by 98 · see citing works
Howarth, J. A., Price, S. C., Dobrota, M., Kentish, P., & Hinton, R. H. (2001) · Toxicology Letters · doi:10.1016/s0378-4274(01)00313-7 · Cited by 94 · see citing works
Takagi, A., Sai, K., Umemura, T., Hasegawa, R., & Kurokawa, Y. (1990) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1990.tb02551.x · Cited by 94 · see citing works
Occurrence of endocrine-disrupting compounds in reclaimed water from Tianjin, China
Wang, Y., Hu, W., Cao, Z., Fu, X., & Zhu, T. (2005) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-005-0082-x · Cited by 91 · see citing works
Modulation of iodide uptake by dialkyl phthalate plasticisers in FRTL-5 rat thyroid follicular cells
Wenzel, A., Franz, C., Breous, E., & Loos, U. (2005) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.02.008 · Cited by 86 · see citing works
Gender-Related Differences in Muscle Injury, Oxidative Stress, and Apoptosis
Kerksick, C. M., Taylor, L. W., Harvey, A. E., & Willoughby, D. S. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31817d1cce · Cited by 83 · see citing works
Health effects of long-term mercury exposure among chloralkali plant workers
Frumkin, H., Letz, R., Williams, P. L., Gerr, F., Pierce, M., Sanders, A., Elon, L., Manning, C. C., Woods, J. S., Hertzberg, V., et al. (2001) · American Journal of Industrial Medicine · doi:10.1002/1097-0274(200101)39:1 · Cited by 78 · see citing works
PPARα‐ and DEHP‐Induced Cancers
Ito, Y., & Nakajima, T. (2008) · PPAR Research · doi:10.1155/2008/759716 · Cited by 52 · see citing works
Isenberg, J. S. (2000) · Toxicological Sciences · doi:10.1093/toxsci/56.1.73 · Cited by 51 · see citing works
Di(2-ethylhexyl)phthalate stimulates Ca2+ entry, chemotaxis and ROS production in human granulocytes
Palleschi, S., Rossi, B., Diana, L., & Silvestroni, L. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.01.031 · Cited by 33 · see citing works
Effect of the dietary exposure of rat to di(2-ethyl hexyl) phthalate on their metabolic efficiency
Bernal, C., Martinelli, M., & Mocchiutti, N. O. (2002) · Food Additives & Contaminants · doi:10.1080/02652030210157709 · Cited by 23 · see citing works
European Union Summary Risk Assessment Report - Bis (2-ethylhexyl) Phthalate (DEHP)
Sazan, P., Karin, A., Orna, C., Bert-Ove, L., Ana, P. P., & Stefania, V. (2008) · Joint Research Centre (European Commission) · Cited by 10 · see citing works
Tian, Y., Ishikawa, H., Piao, F. Y., Yamamoto, H., Yamauchi, T., Duan, Z. W., Zhang, Y. M., Ma, M., & Cui, J. S. (2003) · Journal of Occupational Health · doi:10.1539/joh.45.408 · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Velis, C. A., & Cook, E. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.0c08536 · Cited by 316 · see citing works
Packaging design for the circular economy: A systematic review
Zhu, Z., Liu, W., Ye, S., & Batista, L. (2022) · Sustainable Production and Consumption · doi:10.1016/j.spc.2022.06.005 · Cited by 204 · see citing works
“Additional phthalates may be added in reprocessing recycled plastics (Hahladakis et al., 2018) as well as in a later stage of production (e.g. labelling and gluing), which are generally not removed from recycling of household plastic waste (Wang et al., 2011).”
BackgroundRocha, B. A., Asimakopoulos, A. G., Barbosa, F., & Kannan, K. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.01.193 · Cited by 162 · see citing works
Dibutyl phthalate induced oxidative stress and genotoxicity on adult zebrafish (Danio rerio) brain
Jiang, N., Song, P., Li, X., Zhu, L., Wang, J., Yin, X., & Wang, J. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127749 · Cited by 159 · see citing works
Self-citationMeng, X., Wang, Y., Xiang, N., Chen, L., Liu, Z., Wu, B., Dai, X., Zhang, Y., Xie, Z., & Ebinghaus, R. (2014) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2014.01.007 · Cited by 149 · see citing works
Guo, Y., Weck, J., Sundaram, R., Goldstone, A. E., Louis, G. M. B., & Kannan, K. (2014) · Environmental Science & Technology · doi:10.1021/es5024898 · Cited by 103 · see citing works
Yu, Y., Peng, M., Liu, Y., Ma, J., Wang, N., Ma, S., Feng, N., & Lu, S. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123390 · Cited by 98 · see citing works
Self-citationZhang, B., Zhang, T., Duan, Y., Zhao, Z., Huang, X., Bai, X., Xie, L., He, Y., Ouyang, J., Yang, Y., et al. (2019) · Environment International · doi:10.1016/j.envint.2018.12.035 · Cited by 93 · see citing works
Li, J., Zhang, J., Yadav, M. P., & Li, X. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.02.194 · Cited by 90 · see citing works
Degradation of di-2-ethylhexyl phthalate (DEHP) by an indigenous isolate Acinetobacter sp. SN13
Xu, J., Lu, Q., de Toledo, R. A., & Shim, H. (2017) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2017.01.004 · Cited by 78 · see citing works
Wang, Y., Zhan, W., Ren, Q., Cheng, S., Wang, J., Ma, X., Zhang, C., & Wang, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.06.459 · Cited by 70 · see citing works
Self-citationLee, I., Alakeel, R. A., Kim, S., Al‐Sheikh, Y. A., Al-Mandeel, H. M., Alyousef, A. A., Kho, Y., & Choi, K. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.11.025 · Cited by 55 · see citing works
Hansen, J. F., Bendtzen, K., Boas, M., Frederiksen, H. W., Nielsen, C. H., Rasmussen, Å. K., & Feldt‐Rasmussen, U. (2015) · PLoS ONE · doi:10.1371/journal.pone.0120083 · Cited by 51 · see citing works
Cook, E., Derks, M., & Velis, C. A. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.160385 · Cited by 49 · see citing works
Qu, R., Feng, M., Sun, P., & Wang, Z. (2014) · Environmental Toxicology · doi:10.1002/tox.21985 · Cited by 48 · see citing works
de Oliveira, B. F. A., Chacra, A. P. M., Frauches, T. S., Vallochi, A. L., & Hacon, S. D. S. (2014) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2014.976893 · Cited by 47 · see citing works
Lo, D., Wang, Y., & WU, M. C. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.05.005 · Cited by 46 · see citing works
Environmental Contamination and Human Exposure to Select Endocrine-Disrupting Chemicals: A Review
Sangeetha, S., Vimalkumar, K., & Loganathan, B. G. (2021) · Sustainable Chemistry · doi:10.3390/suschem2020020 · Cited by 39 · see citing works
Wang, X., Wang, L., Zhang, J., Yin, W., Hou, J., Zhang, Y., Hu, C., Wang, G., Zhang, R., Tao, Y., et al. (2018) · Environmental Research · doi:10.1016/j.envres.2018.04.004 · Cited by 35 · see citing works
Self-citationMeng, X., Liu, Q., & Ding, Y. (2016) · Electrophoresis · doi:10.1002/elps.201600439 · Cited by 31 · see citing works
Li, P., Jia, H.-Y., Wang, Y., Li, T., Wang, L., Li, Q., Yang, M., Yue, J.-J., Yi, X., & Guo, L. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.12.246 · Cited by 31 · see citing works
Self-citationHou, J., Yin, W., Li, P., Huang, Y., Wan, Y., Hu, C., Xu, T., Cheng, J., Wang, L., Yu, Z., et al. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.07.113 · Cited by 31 · see citing works
Self-citationLarsen, E. L., Weimann, A., & Poulsen, H. E. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.09.030 · Cited by 30 · see citing works
8-Hydroxyguanine, an Oxidative DNA and RNA Modification
Kasai, H., & Kawai, K. (2016) · RNA technologies · doi:10.1007/978-3-319-34175-0_7 · Cited by 26 · see citing works
Wang, C., Chen, W., Lin, C., Lai, C., Loh, C., Chen, H., & Liou, S.-H. (2016) · Environmental Science and Pollution Research · doi:10.1007/s11356-016-6898-4 · Cited by 26 · see citing works
Environmental endocrine disruptor concentrations in urine samples from Mexican Indigenous women
Rodríguez‐Báez, A. S., Medellín‐Garibay, S. E., Rodríguez‐Aguilar, M., Sagahón‐Azúa, J., Milán‐Segovia, R. D. C., & Flores‐Ramírez, R. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-18197-5 · Cited by 23 · see citing works
Swinnerton, S., Kurtz, K., Neba Nforsoh, S., Craver, V., & Tsai, C. (2024) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2024.143818 · Cited by 19 · see citing works
Hansen, J. F., Brorson, M. M., Boas, M., Frederiksen, H. W., Nielsen, C. H., Lindström, E. S., Hofman-Bang, J., Hartoft‐Nielsen, M., Frisch, T., Main, K. M., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151192 · Cited by 19 · see citing works
Wu, C., Hsiung, C. A., Tsai, H.-J., Cheng, C., Chen, B., Hu, C., Huang, Y., & Wu, M. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115204 · Cited by 13 · see citing works
Rafiee, A., Delgado-Saborit, J. M., Sly, P. D., Amiri, H. M., Mosallaei, S., & Hoseini, M. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.152832 · Cited by 12 · see citing works
Feng, R., Xu, H., Liu, L., Zhou, J., Zhang, H., Shen, Z., Yang, M., Sun, J., Ho, S. S. H., & Cao, J. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126410 · Cited by 6 · see citing works
Chao, U. H. K., de Toledo, R. A., & Shim, H. (2018) · Energy Procedia · doi:10.1016/j.egypro.2018.10.053 · Cited by 2 · see citing works
Tangestani, M., Yazdi, N. B., Arfaeinia, H., Soleimani, F., Zanganeh, Z., Afrashteh, S., Farhadi, A., Moftian, N., Mansouri, M., & Zare, S. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.127494 · Cited by 1 · see citing works
Occupational health and safety in the waste sector: a scoping review and bibliometric analysis
Leonardi, N., Giacomello, G., Caffaro, F., & Pampuro, N. (2026) · Environment Development and Sustainability · doi:10.1007/s10668-026-08275-4
- Authors
- Wang, Q., Wang, L., Chen, X., Rao, K. M., Lu, S. Y., Ma, S. T., Jiang, P., Zheng, D., Xu, S. Q., Zheng, H. Y., Wang, J. S., Yu, Z. Q., Zhang, R., Tao, Y., & Yuan, J.
- Affiliations
- Huazhong University of Science and Technology (CN)
- Chinese Center For Disease Control and Prevention (CN)
- Chinese Academy of Sciences (CN)
- Corresponding author
- Yu, Zhi Qiang
- Zhang, Rong
- Yuan, Jing
- Venue
- Environmental Science and Pollution Research
- Published
- 2011-02-06
- Volume
- 18
- Issue
- 6
- Pages
- 987-996
- ISSN
- 0944-1344 (ISSN-L)
- 1614-7499
- OpenAlex
- W2004487054
- Cited by
- 35
- References
- 51
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 5
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Environmental Science and Pollution Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Environmental Protection Agency
- National Natural Science Foundation of China
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Keywords
- DEHP, occupational exposure, urinary 8-hydroxy-2'-deoxyguanosine, oxidative DNA damage, malondialdehyde, superoxide dismutase, occupational health, plasticizers, environmental contamination, occupational risk factors
- MeSH terms
- 8-Hydroxy-2'-Deoxyguanosine, Adult, China, Cross-Sectional Studies, Deoxyguanosine, Diethylhexyl Phthalate, Environmental Monitoring, Female, Humans, Industrial Waste, Interviews as Topic, Male, Malondialdehyde, Middle Aged, Plasticizers, Plastics, Surveys and Questionnaires, Soil, Superoxide Dismutase, Thyrotropin, Water, Biomarkers, Case-Control Studies, Occupational Exposure, Recycling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
