Validation of an Acoustic Gastrointestinal Surveillance Biosensor for Postoperative Ileus
Abstract
Background Postoperative ileus (POI) can worsen outcomes, increase cost, and prolong hospitalization. An objective marker could help identify POI patients who should not be prematurely fed. We developed a disposable, non-invasive acoustic gastro-intestinal surveillance (AGIS) biosensor. We tested whether AGIS can distinguish healthy controls from patients recovering from abdominal surgery.Study design AGIS is a disposable plastic device embedded with a microphone that adheres to the abdominal wall and connects to a computer that measures acoustic event rates. We compared intestinal rates of healthy subjects using AGIS for 60 min after a standardized meal to recordings of two postoperative groups: (1) patients tolerating standardized feeding and (2) POI patients. We compared intestinal rates among groups using ANOVA and t tests.Results There were 8 healthy controls, 7 patients tolerating feeding, and 25 with POI; mean intestinal rates were 0.14, 0.03, and 0.016 events per second, respectively (ANOVA p < 0.001). AGIS separated patients from controls with 100 % sensitivity and 97 % specificity. Among patients, rates were higher in fed versus POI subjects (p = 0.017).Conclusion Non-invasive, abdominal acoustic monitoring distinguishes POI from non-POI subjects. Future research will test whether AGIS can identify patients at risk for development of POI and assist with postoperative feeding decisions.
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The Gastrointestinal Logic AbStats system provides real-time digestive telemetry via noninvasive vibration and sound sensing to assess postsurgery GI tract re-engagement.
“The Gastrointestinal Logic AbStats system (CA, USA) provides real-time digestive telemetry via noninvasive vibration and sound sensing to assess postsurgery GI tract re-engagement [23].”
From Wearables and the Medical Revolution (2018) · cites this paper as [23]
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- Authors
- Spiegel, B. M. R., Kaneshiro, M., Russell, M. M., Lin, A., Patel, A., Tashjian, V. C., Zegarski, V., Singh, D., Cohen, S. E., Reid, M. W., Whitman, C. B., Talley, J., Martinez, B. M., & Kaiser, W.
- Affiliations
- VA Greater Los Angeles Healthcare System (US)
- University of California, Los Angeles (US)
- Cedars-Sinai Medical Center (US)
- Corresponding author
- Spiegel, Brennan M.R.
- Kaiser, William
- ORCID
- Venue
- Journal of Gastrointestinal Surgery
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 18
- Issue
- 10
- Pages
- 1795-1803
- ISSN
- 1091-255X (ISSN-L)
- OpenAlex
- W2029065884
- Cited by
- 50
- References
- 22
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 4 · 2023: 2 · 2022: 8 · 2021: 7 · 2020: 5 · 2019: 1 · 2018: 5 · 2017: 2 · 2016: 2 · 2015: 4
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Gastrointestinal Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
- Keywords
- postoperative ileus, biosensors, intestinal motility, non-invasive monitoring, abdominal surgery, postoperative feeding, early enteral nutrition, diagnostic accuracy
- MeSH terms
- Acoustics, Adult, Aged, Cross-Sectional Studies, Equipment Design, Female, Gastrointestinal Motility, Humans, Male, Middle Aged, Monitoring, Physiologic, Postoperative Period, Reproducibility of Results, Biosensing Techniques, Ileus
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