Primary Care Patients with Opioid Use Disorder Have a High Prevalence of Pain and Mental Health and Other Substance Use Disorders
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Anxiety and chronic pain diagnoses co-occur at a high rate, particularly among the OUD population.
“Anxiety and chronic pain diagnoses co-occur at a high rate, particularly among the OUD population”
From Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study (2023) · cites this paper as [50]
The Results and Table 1 report high rates of pain and anxiety among primary care patients with OUD, and the Discussion describes pain and mental-health comorbidity in this group. The paper does not report the rate at which anxiety and chronic pain diagnoses occur together; its measured pain category is not limited to chronic pain. It also does not compare that co-occurrence rate with people without OUD. (LLM, conf=0.85)
Experimental — accuracy not yet measuredAnxiety disorders can increase risk of relapse among patients undergoing buprenorphine/naloxone treatment.
“anxiety disorders can increase risk of relapse among patients undergoing buprenorphine/naloxone treatment 49,50.”
From Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study (2023) · cites this paper as [50]
Table 2 reports the prevalence of anxiety among primary care patients with opioid use disorder, and the Methods describe a cross-sectional analysis of comorbidities. The paper does not address whether anxiety increases relapse risk during buprenorphine/naloxone treatment (searched: anxiety relapse buprenorphine/naloxone; risk of relapse during medication treatment). (LLM, conf=0.78)
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Cites
Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017
Scholl, L., Seth, P., Kariisa, M., Wilson, N. O., & Baldwin, G. T. (2018) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm675152e1 · Cited by 1,734 · see citing works
Swendsen, J. D., Conway, K. P., Degenhardt, L. J., Glantz, M. D., Jin, R., Merikangas, K. R., Sampson, N. A., & Kessler, R. C. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.02902.x · Cited by 599 · see citing works
Prevention and Treatment of Opioid Misuse and Addiction: A Review
Volkow, N. D., Jones, E. B., Einstein, E. B., & Wargo, E. M. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.3126 · Cited by 596 · see citing works
Primary Care–Based Models for the Treatment of Opioid Use Disorder
Korthuis, P. T., McCarty, D. W., Weimer, M. B., Bougatsos, C., Blazina, I., Zakher, B., Grusing, S., Devine, B., & Chou, R. (2016) · Annals of Internal Medicine · doi:10.7326/m16-2149 · Cited by 296 · see citing works
Glass, J. E., Bobb, J. F., Lee, A. K., Richards, J. A., Lapham, G. T., Ludman, E. J., Achtmeyer, C. E., Caldeiro, R. M., Parrish, R. S., Williams, E. C., et al. (2018) · Implementation Science · doi:10.1186/s13012-018-0795-9 · Cited by 72 · see citing works
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Schuman‐Olivier, Z., Fatkin, T., Creedon, T. B., Samawi, F., Moore, S. K., Okst, K., Fredericksen, A. (., Oxnard, A. (., Roll, D., Smith, L., et al. (2023) · The American Journal on Addictions · doi:10.1111/ajad.13364 · Cited by 15 · see citing works
- Authors
- Simon, C. B., Klein, J. W., Bradley, K. A., & Oliver, M.
- Affiliations
- University of Washington (US)
- Kaiser Permanente Washington Health Research Institute (US)
- Corresponding author
- Simon, Claire B.
- Venue
- Journal of General Internal Medicine
- Published
- 2020-05-29
- Volume
- 36
- Issue
- 6
- Pages
- 1799-1801
- ISSN
- 0884-8734 (ISSN-L)
- 1525-1497
- PMC
- PMC8175533
- OpenAlex
- W3031071466
- Cited by
- 8
- References
- 5
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of General Internal Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Agency for Healthcare Research and Quality (R18 HS023173)
- National Institute on Alcohol Abuse and Alcoholism (K24 AA022128)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- opioid use disorder, comorbidities, pain disorders, insomnia, mental illness, substance use disorders, alcoholism, cannabis use disorder, stimulant use disorder, behavioral health integration, primary care, buprenorphine, Kaiser Permanente Washington
- MeSH terms
- Analgesics, Opioid, Mental Disorders, Humans, Mental Health, Opioid-Related Disorders, Pain, Primary Health Care, Prevalence, Substance-Related Disorders
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