Abies koreana Essential Oil Inhibits Drug‐Resistant Skin Pathogen Growth and LPS‐Induced Inflammatory Effects of Murine Macrophage
Abstract
Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), IL-6, NO and PGE(2) in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Abies koreana essential oil inhibitory effects on NO and PGE2 are related to modulation of iNOS and COX-2 expression, with reduced iNOS and COX-2 mRNA and protein.
“The inhibitory effects of Abies koreana Horstmann’s Silberlocke essential oil, mainly constituted by bornyl acetate, limonene and α-pinene, on pro-inflammatory mediators (NO and PGE2) were related to the modulation of iNOS and COX-2 expression, since the expression of iNOS and COX-2 mRNA and iNOS and COX-2 protein was reduced [143].”
From Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review (2010) · cites this paper as [143]
The citation lists haven’t been fetched yet
References 24 · Cited by 83
- Authors
- Yoon, W., Kim, S., Oh, T., Lee, N. H., & Hyun, C.
- Affiliations
- Research Group for Cosmetic Materials Jeju Biodiversity Research Institute (JBRI), Jeju High‐Tech Development Institute (HiDI) Jeju 697‐943 Korea
- Jeju National University (KR)
- Corresponding author
- Hyun, Chang‐Gu
- Venue
- Lipids
- Publisher
- Wiley
- Published
- 2009-04-07
- Volume
- 44
- Issue
- 5
- Pages
- 471-476
- ISSN
- 0024-4201 (ISSN-L)
- 1558-9307
- OpenAlex
- W1997579620
- Cited by
- 83
- References
- 24
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 6 · 2021: 6 · 2020: 4 · 2019: 1 · 2018: 4 · 2017: 10 · 2016: 2 · 2015: 5 · 2014: 5 · 2013: 6 · 2012: 1
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Lipids (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- acne, Propionibacterium acnes, Staphylococcus epidermidis, antibiotic resistance, antibacterial activity, anti-inflammatory activity, lipopolysaccharide-induced inflammation, macrophages, inflammatory cytokines, nitric oxide, prostaglandin E2, skin health
- MeSH terms
- Acne Vulgaris, Animals, Anti-Inflammatory Agents, Anti-Bacterial Agents, Cell Line, Drug Resistance, Inflammation, Lipopolysaccharides, Macrophages, Microbial Sensitivity Tests, Oils, Volatile, Propionibacterium acnes, Staphylococcus epidermidis, Biomarkers, Abies, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
