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Clonal Hematopoiesis and Myeloid Neoplasms in the Context of Telomere Biology Disorders
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“However, individuals with biallelic mutations in ERCC6L6 (ref. 28) and telomere biology disorders29 are known to be prone to acute myeloid leukemia (AML) driven by mutations in the DDR pathway, including TP53 and PPM1D.”
From Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy (2025) · cites this paper as [29]
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Cites
Telomeres and telomerase: three decades of progress
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Telomere dysfunction in ageing and age-related diseases
Rossiello, F., Jurk, D., Passos, J. F., & d’Adda di Fagagna, F. (2022) · Nature Cell Biology · doi:10.1038/s41556-022-00842-x · Cited by 754
Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study
Takahashi, K., Wang, F., Kantarjian, H., Doss, D., Khanna, K., Thompson, E., Zhao, L., Patel, K., Neelapu, S., Gumbs, C., et al. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(16)30626-x · Cited by 399
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Cited by
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy
Liu, J., Tran, D., Xue, L., Wiley, B. J., Vlasschaert, C., Watson, C. J., MacGregor, H. A. J., Zong, X., Chan, I. C. C., Das, I., et al. (2025) · Nature Genetics · doi:10.1038/s41588-025-02250-x · Cited by 33
Metadata
- Authors
- Ferrer, A., Mangaonkar, A. A., & Patnaik, M. M.
- Venue
- Current Hematologic Malignancy Reports
- Published
- 2022-05-07
- Volume
- 17
- Issue
- 3
- Pages
- 61-68
- ISSN
- 1558-8211
- 1558-822X
- PMC
- PMC9077347
- Cited by
- 30
- References
- 3
- Language
- en
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- Ferrer, A., Mangaonkar, A. A., & Patnaik, M. M. (2022). Clonal Hematopoiesis and Myeloid Neoplasms in the Context of Telomere Biology Disorders. Current Hematologic Malignancy Reports. https://doi.org/10.1007/s11899-022-00662-8